Imaging of central nAChReceptors with 2-[18F]F-A85380: Optimized synthesis and in vitro evaluation in Alzheimer's disease

Applied Radiation and Isotopes

Volumn 61, Issue 6, 2004, Pages 1235-1240

  Schmaljohann, J ^a   Minnerop, M ^a   Karwath, P ^a   Gundisch D ^a   Falkai, P ^a   Guhlke, S ^a   Wullner U ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

2 18F A85380; Alzheimer's disease; Fluorine 18; Nicotinic acetylcholine receptor; PET

Indexed keywords

BRAIN; DIAGNOSIS; OPTIMIZATION; RADIOGRAPHY; RADIOISOTOPES;

AUTORADIOGRAPHY; HUMAN BRAIN; NEURODEGENERATIVE DISORDERS;

IMAGING TECHNIQUES;

2 FLUORO 3 [2 (2 AZETIDINYLMETHOXY)]PYRIDINE F 18; CONTRAST MEDIUM; F A85380; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BABOON; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DIAGNOSTIC IMAGING; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; INCUBATION TIME; NERVE CELL; NONHUMAN; OCCIPITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; THALAMUS;

ALZHEIMER DISEASE; ANIMALS; AZETIDINES; BRAIN; FLUORINE RADIOISOTOPES; HUMANS; ISOTOPE LABELING; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; TISSUE DISTRIBUTION;

EID: 4544243342     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2004.02.026     Document Type: Article

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