Glycine propionyl-L-carnitine increases plasma nitrate/nitrite in resistance trained men

Journal of the International Society of Sports Nutrition

Volumn 4, Issue , 2007, Pages

  Bloomer, Richard J ^a   Smith, Webb A ^a   Fisher Wellman, Kelsey H ^a  

^a UNIVERSITY OF MEMPHIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 45249114711     PISSN: None     EISSN: 15502783     Source Type: Journal    
DOI: 10.1186/1550-2783-4-22     Document Type: Article

References (32)

1. Maiorana A O'Driscoll G Taylor R Green D Exercise and the nitric oxide vasodilator system Sports Med 2003, 33(14):1013-1035 10.2165/ 00007256-200333140-00001 14599231
2. Collier J Vallance P Physiological importance of nitric oxide BMJ 1991, 32:1289-1290
3. Joannides R Haefeli WE Linder L Richard V Bakkali EH Thuillez C Luscher TF Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo Circulation 1995, 91(5):1314-1319 7867167
4. Hickner RC Fisher JS Ehsani AA Kohrt WM Role of nitric oxide in skeletal muscle blood flow at rest and during dynamic exercise in humans Am J Physiol 1997, 273(1 Pt 2):H405-410 9249515
5. Duffy SJ Castle SF Harper RW Meredith IT Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation Circulation 1999, 100:1951-1957 10556220
6. Dyke CK Proctor DN Dietz NM Joyner MJ Role of nitric oxide in exercise hyperemia during prolonged rhythmic handgripping in humans J Physiol (Lond) 1995, 488:259-265 1156719 8568663
7. Gilligan DM Panza JA Kilcoyne CM Waclawiw MA Casino PR Quyyumi AA Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation Circulation 1994, 90:2853-2858 7994830
8. Ambring A Benthin G Petersson AS Jungerstenm L Wennmalm A Indirect evidence of increased expression of NO synthase in marathon runners, and up regulation of NO synthase activity during running Circulation 90, I-137 (abstract)
9. Bode-Boger SM Boger RH Scroder EP Frolich JC Exercise increases systemic nitric oxide production in men J Cardiovasc Risk 1994, 1:173-178 7606631
10. Clarkson P Montgomery HE Mullen MJ Donald AE Powe AJ Bull T Jubb M World M Deanfield JE Exercise training enhances endothelial function in young men J Am Coll Cardiol 1999 33 1379 1385 10.1016/S0735-1097(99)00036-4 10193742
11. DeSouza CA Shapiro LF Clevenger C Dinenno F Monahan M Tanka H Seals DR Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men Circulation 2000, 102:1351-1357 10993851
12. Di Massimo C Scarpelli P Tozzi-Ciancarelli MG Possible involvement of oxidative stress in exercise-mediated platelet activation Clin Hemorheol Microcirc 2004, 30(3-4):313-316 15258360
13. Tozzi-Ciancarelli MG Penco M Di Massimo C Influence of acute exercise on human platelet responsiveness: Possible involvement of exercise-induced oxidative stress Eur J Appl Physiol 2002, 86(3):266-272 10.1007/ s00421-001-0542-8 11990737
14. Edwards DG Schofield RS Lennon SL Pierce GL Nichol WW Braith RW Effect of exercise training on endothelial function in men with coronary artery disease Am J Cardiol 2004, 93(5):617-20 10.1016/j.amjcard.2003.11.032 14996592
15. Tordi N Colin E Mourot L Bouhaddi M Regnard J Laurant P Effects of resuming endurance training on arterial stiffness and nitric oxide production during exercise in elite cyclists Appl Physiol Nutr Metab 2006, 31(3):244-249 10.1139/H05-033 16770351
16. Poveda JJ Riestra A Salas E Cagigas ML Lopez-Somoza C Amado JA Berrazueta JR Contribution of nitric oxide to exercise-induced changes in healthy volunteers: Effects of acute exercise and long-term physical training Eur J Clin Invest 1997. 27(11):967-971 10.1046/ j.1365-2362.1997.2220763.x 9395795
17. Burgaud JL Ongini E Del Soldato P Nitric oxide-releasing drugs: A novel class of effective and safe therapeutic agents Ann N Y Acad Sci 2002, 962:360-71 12076987
18. Bloomer RJ Tschume LC Smith WA Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects Int J Vitam Nutr Res
19. Loffredo L Marcoccia A Pignatelli P Andreozzi P Borgia MC Cangemi R Chiarotti F Violi F Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease Eur Heart J 2007, 28(5):608-612 10.1093/eurheartj/ehl533 17298965
20. Cipolla MJ Nicoloff A Rebello T Amato A Porter JM Propionyl-L-carnitine dilates human subcutaneous arteries through an endothelium-dependent mechanism J Vasc Surg 1999, 29(6):1097-1103 10.1016/ S0741-5214(99)70251-X 10359944
21. Hafidi ME Perez I Banos G Is glycine effective against elevated blood pressure? Curr Opin Clin Nutr Metab Care 2006, 9:26-31 16444815
22. Stephens FB Constantin-Teodosiu D Laithwaite D Simpson EJ Greenhaff PL Insulin stimulates L-carnitine accumulation in human skeletal muscle FASEB J 2006, 20(2):377-379 16368715
23. Stephens FB Evans CE Constantin-Teodosiu D Greenhaff PL Carbohydrate ingestion augments L-carnitine retention in humans J Appl Physiol 2007, 102(3):1065-1070 10.1152/japplphysiol.01011.2006 17138832
24. Doshi SN Naka KK Payne N Jones CJ Ashton M Lewis MJ Goodfellow J Flow-mediated dilatation following wrist and upper arm occlusion in humans: The contribution of nitric oxide Clin Sci (Lond) 2001, 101(6):629-635 11724650
25. Engelke KA Halliwill JR Proctor DR Dietz NM Joyner MJ Contribution of nitric oxide and prostaglandins to reactive hyperemia in the human forearm J Appl Physiol 1996, 81(4):1807-1814 8904603
26. Meredith IT Currie KE Anderson TJ Roddy MA Ganz P Creager MA Postischemic vasodilation in human forearm is dependent on endothelium-derived nitric oxide Am J Physiol 1996, 270(4 Pt 2):H1435-1440 8967386
27. Mullen MJ Kharbanda RK Cross J Donald AE Taylor M Vallance P Deanfield JE MacAllister RJ Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: Relevance to endothelial dysfunction in hypercholesterolemia Circ Res 2001, 88(2):145-151 11157665
28. Miyachi M Iemitsu M Okutsu M Onodera S Effects of endurance training on the size and blood flow of the arterial conductance vessels in humans Acta Physiol Scand 1998, 163(1):13-6 10.1046/j.1365-201x.1998.0337f.x 9648618
29. Killewich LA Tuvdendorj D Bahadorani J Hunter GC Wolfe RR Amino acids stimulate leg muscle protein synthesis in peripheral arterial disease J Vasc Surg 2007, 45(3):554-559 discussion 559-60 10.1016/ j.jvs.2006.11.033 17321342
30. Pignatelli P Lenti L Sanguigni V Frati G Simeoni I Gazzaniga PP Pulcinelli FM Violi F Carnitine inhibits arachidonic acid turnover, platelet function, and oxidative stress Am J Physiol Heart Circ Physiol 2003, 284(1):H41-8 12388290
31. Zalba G San Jose G Moreno MU Fortuno MA Fortuno A Beaumont FJ Diez J Oxidative stress in arterial hypertension: Role of NAD(P)H oxidase Hypertension 2001, 38(6):1395-9 10.1161/hy1201.099611 11751724
32. de Sotomayor MA Mingorance C Rodriguez-Rodriguez R Marhuenda E Herrera MD l-carnitine and its propionate improvement of endothelial function in SHR through superoxide dismutase-dependent mechanisms Free Radic Res 2007, 41(8):884-891 10.1080/10715760701416467 17654045