Experimental models of β-cell regeneration

Biochemical Society Transactions

Volumn 36, Issue 3, 2008, Pages 286-289

  Bonal, Claire ^a   Avril, Isabelle ^a   Herrera, Pedro L ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

cell regeneration; Diabetes; Glucose metabolism; Pancreas; Transgenic model

Indexed keywords

ALLOXAN; STREPTOZOCIN;

ACINAR CELL; ALLOXAN DIABETES MELLITUS; APOPTOSIS; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL REGENERATION; CELL STRUCTURE; CONFERENCE PAPER; DIABETOGENESIS; EXPERIMENTAL MODEL; GENETIC DISORDER; HOMEOSTASIS; INNER CELL MASS; INSULIN DEPENDENT DIABETES MELLITUS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS DUCT; PANCREAS DUCT LIGATION; PANCREAS ISLET BETA CELL; PANCREAS RESECTION; PRIORITY JOURNAL; STEM CELL; STREPTOZOCIN DIABETES; SURGICAL INJURY;

ANIMALS; HUMANS; INSULIN-SECRETING CELLS; MODELS, BIOLOGICAL; REGENERATION;

RODENTIA;

EID: 45249091263     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0360286     Document Type: Conference Paper

References (40)

1. Berrocal, T., Luque, A.A., Pinilla, I. and Lassaletta, L. (2005) Pancreatic regeneration after near-total pancreatectomy in children with nesidioblastosis. Pediatr. Radiol. 35, 1066-1070
2. Schonau, E., Deeg, K.H., Huemmer, H.P., Akcetin, Y.Z. and Bohles, H.J. (1991) Pancreatic growth and function following surgical treatment of nesidioblastosis in infancy. Eur. J. Pediatr. 150, 550-553
3. Weir, G.C. and Bonner-Weir, S. (2004) Five stages of evolving β-cell dysfunction during progression to diabetes. Diabetes 53 (Suppl. 3), S16-S21
4. Prentki, M. and Nolan, C.J. (2006) Islet β-cell failure in type 2 diabetes. J. Clin. Invest. 116, 1802-1812
5. Meier, J.J., Lin, J.C., Butler, A.E., Galasso, R., Martinez, D.S. and Butler, P.C. (2006) Direct evidence of attempted β-cell regeneration in an 89-year-old patient with recent-onset type 1 diabetes. Diabetologia 49, 1838-1844
6. Kodama, S., Toyonaga, T., Kondo, T., Matsumoto, K., Tsuruzoe, K., Kawashima, J., Goto, H., Kume, K., Kume, S., Sakakida, M. and Araki, E. (2005) Enhanced expression of PDX-1 and Ngn3 by exendin-4 during β-cell regeneration in STZ-treated mice. Biochem. Biophys. Res. Commun. 327, 1170-1178
7. Holland, A.M., Hale, M.A., Kagami, H., Hammer, R.E. and MacDonald, R.J. (2002) Experimental control of pancreatic development and maintenance. Proc. Natl. Acad. Sci. U.S.A. 99, 12236-12241
8. Holland, A.M., Gonez, L.J., Naselli, G., Macdonald, R.J. and Harrison, L.C. (2005) Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of β-cells in the adult pancreas. Diabetes 54, 2586-2595
9. Okamoto, H. (1999) The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic β-cells. J. Hepatobiliary Pancreat. Surg. 6, 254-262
10. ATP channel. Proc. Natl. Acad. Sci. U.S.A. 94, 11969-11973
11. Oyama, K., Minami, K., Ishizaki, K., Fuse, M., Miki, T. and Seino, S. (2006) Spontaneous recovery from hyperglycemia by regeneration of pancreatic β-cells in Kir6.2G132S transgenic mice. Diabetes 55, 1930-1938
12. 11a Nir, T., Melton, D.A. and Dor, Y. (2007) Recovery from diabetes in mice by β-cell regeneration. J. Clin. Invest. 117, 2553-2561
13. Lenzen, S. (2008) The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 51, 216-226
14. Bolzan, A.D. and Bianchi, M.S. (2002) Genotoxicity of streptozotocin. Mutat. Res. 512, 121-134
15. Like, A.A. and Rossini, A.A. (1976) Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science 193, 415-417
16. Li, L., Yi, Z., Seno, M. and Kojima, I. (2004) Activin A and betacellulin: effect on regeneration of pancreatic β-cells in neonatal streptozotocin-treated rats. Diabetes 53, 608-615
17. Thyssen, S., Arany, E. and Hill, D.J. (2006) Ontogeny of regeneration of β-cells in the neonatal rat after treatment with streptozotocin. Endocrinology 147, 2346-2356
18. Fernandes, A., King, L.C., Guz, Y., Stein, R., Wright, C.V. and Teitelman, G. (1997) Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology 138, 1750-1762
19. Kim, B.M., Han, Y.M., Shin, Y.J., Min, B.H. and Park, I.S. (2001) Clusterin expression during regeneration of pancreatic islet cells in streptozotocin-induced diabetic rats. Diabetologia 44, 2192-2202
20. Aughsteen, A.A. (2002) Immunofluorescence and electron-microscopic observations of intermediate cells in the pancreas of mice, rats and humans. Cells Tissues Organs 170, 21-28
21. De Haro-Hernandez, R., Cabrera-Munoz, L. and Mendez, J.D. (2004) Regeneration of β-cells and neogenesis from small ducts or acinar cells promote recovery of endocrine pancreatic function in alloxan-treated rats. Arch. Med. Res. 35, 114-120
22. Bonner-Weir, S. and Sharma, A. (2002) Pancreatic stem cells. J. Pathol. 197, 519-526
23. Peshavaria, M., Larmie, B.L., Lausier, J., Satish, B., Habibovic, A., Roskens, V., Larock, K., Everill, B., Leahy, J.L. and Jetton, T.L. (2006) Regulation of pancreatic β-cell regeneration in the normoglycemic 60% partial-pancreatectomy mouse. Diabetes 55, 3289-3298
24. Dor, Y., Brown, J., Martinez, O.I. and Melton, D.A. (2004) Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41-46
25. Hardikar, A.A., Karandikar, M.S. and Bhonde, R.R. (1999) Effect of partial pancreatectomy on diabetic status in BALB/c mice. J. Endocrinol. 162, 189-195
26. Liu, Y.Q., Montanya, E. and Leahy, J.L. (2001) Increased islet DNA synthesis and glucose-derived lipid and amino acid production in association with β-cell hyperproliferation in normoglycaemic 60% pancreatectomy rats. Diabetologia 44, 1026-1033
27. Liu, Y.Q., Nevin, P.W. and Leahy, J.L. (2000) β-cell adaptation in 60% pancreatectomy rats that preserves normoinsulinemia and normoglycemia. Am. J. Physiol. Endocrinol. Metab. 279, E68-E73
28. tee, C.S., De Leon, D.D., Kaestner, K.H. and Stoffers, D.A. (2006) Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes 55, 269-272
29. Jetton, T.L., Liu, Y.Q., Trotman, W.E., Nevin, P.W., Sun, X.J. and Leahy, J.L. (2001) Enhanced expression of insulin receptor substrate-2 and activation of protein kinase B/Akt in regenerating pancreatic duct epithelium of 60%-partial pancreatectomy rats. Diabetologia 44, 2056-2065
30. Brockenbrough, J.S., Weir, G.C. and Bonner-Weir, S. (1988) Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats. Diabetes 37, 232-236
31. Bonner-Weir, S., Baxter, L.A., Schuppin, G.T. and Smith, F.E. (1993) A second pathway for regeneration of adult exocrine and endocrine pancreas: a possible recapitulation of embryonic development. Diabetes 42, 1715-1720
32. Oh, B.K., Seong, J.K., Lee, J.E., Chae, K.J., Roh, K.J., Park, C. and Park, Y.N. (2002) Induction of telomerase activity during an early burst of proliferation in pancreatic regeneration. Cancer Lett. 186, 93-98
33. Sharma, A., Zangen, D.H., Reitz, P., Taneja, M., Lissauer, M.E., Miller, C.P., Weir, G.C., Habener, J.F. and Bonner-Weir, S. (1999) The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 48, 507-513
34. Finegood, D.T., Weir, G.C. and Bonner-Weir, S. (1999) Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats. Am. J. Physiol. 276, E822-E827
35. De Breuck, S., Lardon, J., Rooman, I. and Bouwens, L. (2003) Netrin-1 expression in fetal and regenerating rat pancreas and its effect on the migration of human pancreatic duct and porcine islet precursor cells. Diabetologia 46, 926-933
36. Baeyens, L., De Breuck, S., Lardon, J., Mfopou, J.K., Rooman, I. and Bouwens, L. (2005) In vitro generation of insulin-producing β-cells from adult exocrine pancreatic cells. Diabetologia 48, 49-57
37. De Breuck, S., Baeyens, L. and Bouwens, L. (2006) Expression and function of leukaemia inhibitory factor and its receptor in normal and regenerating rat pancreas. Diabetologia 49, 108-116
38. Xu, X., D'Hoker, J., Stangé, G., Bonné, S., De Leu, N., Xiao, X., Van de Casteele, M., Mellitzer, G., Ling, Z., Pipeleers, D. et al. (2008) β-Cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132, 197-207
39. Rosenberg, L. (1998) Induction of islet cell neogenesis in the adult pancreas: the partial duct obstruction model. Microsc. Res. Tech. 43, 337-346
40. Rosenberg, L., Brown, R.A. and Duguid, W.P. (1983) A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas. J. Surg. Res. 35, 63-72