-
1
-
-
27744440147
-
Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein
-
den Besten W, Kuo ML, Williams RT, Sherr CJ. Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein. Cell Cycle 2005; 4: 1593-1598.
-
(2005)
Cell Cycle
, vol.4
, pp. 1593-1598
-
-
den Besten, W.1
Kuo, M.L.2
Williams, R.T.3
Sherr, C.J.4
-
2
-
-
36348993742
-
The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence
-
Cheng K, Grisendi S, Clohessy JG, Majid S, Bernardi R, Sportoletti P et al. The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence. Oncogene 2007; 22: 7391-7400.
-
(2007)
Oncogene
, vol.22
, pp. 7391-7400
-
-
Cheng, K.1
Grisendi, S.2
Clohessy, J.G.3
Majid, S.4
Bernardi, R.5
Sportoletti, P.6
-
3
-
-
33645526300
-
Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant
-
Colombo E, Martinelli P, Zamponi R, Shing DC, Bonetti P, Luzi L et al Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant. Cancer Res 15; 66: 3044-3050.
-
Cancer Res
, vol.15
, Issue.66
, pp. 3044-3050
-
-
Colombo, E.1
Martinelli, P.2
Zamponi, R.3
Shing, D.C.4
Bonetti, P.5
Luzi, L.6
-
4
-
-
26444561851
-
Nucleophosmin is required for DNA integrity and p19 Arf protein stability
-
Colombo E, Bonetti P, Lazzerini Denchi E, Martinelli P, Zamponi R, Marine JC et al. Nucleophosmin is required for DNA integrity and p19 Arf protein stability. Mol Cell Biol 2005; 25: 8874-8886.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8874-8886
-
-
Colombo, E.1
Bonetti, P.2
Lazzerini Denchi, E.3
Martinelli, P.4
Zamponi, R.5
Marine, J.C.6
-
5
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281-1284.
-
(1994)
Science
, vol.263
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
Dittmer, K.G.4
Shapiro, D.N.5
Saltman, D.L.6
-
6
-
-
0030022316
-
The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion
-
Redner RL, Rush EA, Faas S, Rudert WA, Corey SJ. The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion. Blood 1996; 87: 882-886.
-
(1996)
Blood
, vol.87
, pp. 882-886
-
-
Redner, R.L.1
Rush, E.A.2
Faas, S.3
Rudert, W.A.4
Corey, S.J.5
-
7
-
-
0030071926
-
The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukaemia produces a novel fusion gene, NPM-MLF1
-
Yoneda-Kato N, Look AT, Kirstein MN, Valentine MB, Raimondi SC, Cohen KJ et al. The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukaemia produces a novel fusion gene, NPM-MLF1. Oncogene 1996; 12: 265-275.
-
(1996)
Oncogene
, vol.12
, pp. 265-275
-
-
Yoneda-Kato, N.1
Look, A.T.2
Kirstein, M.N.3
Valentine, M.B.4
Raimondi, S.C.5
Cohen, K.J.6
-
8
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 2005; 332: 254-266.
-
(2005)
N Engl J Med
, vol.332
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
Alcalay, M.4
Rosati, R.5
Pasqualucci, L.6
-
9
-
-
28444449081
-
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
-
Schnittger S, Schoch C, Kern W, Mecucci C, Tschulik C, Martelli MF et al. Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype. Blood 2005; 106: 3733-3739.
-
(2005)
Blood
, vol.106
, pp. 3733-3739
-
-
Schnittger, S.1
Schoch, C.2
Kern, W.3
Mecucci, C.4
Tschulik, C.5
Martelli, M.F.6
-
10
-
-
28444446313
-
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
Verhaak RG, Goudswaard CS, van Putten W, Bijl MA, Sanders MA, Hugens W et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood 2005; 106: 3747-3754.
-
(2005)
Blood
, vol.106
, pp. 3747-3754
-
-
Verhaak, R.G.1
Goudswaard, C.S.2
van Putten, W.3
Bijl, M.A.4
Sanders, M.A.5
Hugens, W.6
-
11
-
-
28444473100
-
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: Interaction with other gene mutations
-
Dohner K, Schlenk RF, Habdank M, Scholl C, Rucker FG, Corbacioglu A et al. Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations. Blood 2005; 106: 3740-3746.
-
(2005)
Blood
, vol.106
, pp. 3740-3746
-
-
Dohner, K.1
Schlenk, R.F.2
Habdank, M.3
Scholl, C.4
Rucker, F.G.5
Corbacioglu, A.6
-
12
-
-
24144494881
-
Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia
-
Suzuki T, Kiyoi H, Ozeki K, Tomita A, Yamaji S, Suzuki R et al. Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. Blood 2005; 106: 2854-2861.
-
(2005)
Blood
, vol.106
, pp. 2854-2861
-
-
Suzuki, T.1
Kiyoi, H.2
Ozeki, K.3
Tomita, A.4
Yamaji, S.5
Suzuki, R.6
-
13
-
-
34547954572
-
The incidence and clinical significance of nucleophosmin mutations in childhood AML
-
Brown P, McIntyre E, Rau R, Meshinchi S, Lacayo N, Dahl G et al. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood 2007; 110: 979-985.
-
(2007)
Blood
, vol.110
, pp. 979-985
-
-
Brown, P.1
McIntyre, E.2
Rau, R.3
Meshinchi, S.4
Lacayo, N.5
Dahl, G.6
-
14
-
-
0036234459
-
Missing pieces in the NF-kB puzzle
-
Ghosh S, Karin M. Missing pieces in the NF-kB puzzle. Cell 2002; 109: 81-96.
-
(2002)
Cell
, vol.109
, pp. 81-96
-
-
Ghosh, S.1
Karin, M.2
-
15
-
-
0742324492
-
-
Turco MC, Romano MF, Petrella A, Bisogni R, Tassone P, Venuta S. NF-kB/ Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors. Leukemia 2003; 18: 1-7.
-
Turco MC, Romano MF, Petrella A, Bisogni R, Tassone P, Venuta S. NF-kB/ Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors. Leukemia 2003; 18: 1-7.
-
-
-
-
16
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001; 98: 2301-2307.
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
-
17
-
-
85047699198
-
Nuclear transcription factor-kB as a target for cancer drug development
-
Garg A, Aggarwal BB. Nuclear transcription factor-kB as a target for cancer drug development. Leukemia 2002; 16: 1053-1068.
-
(2002)
Leukemia
, vol.16
, pp. 1053-1068
-
-
Garg, A.1
Aggarwal, B.B.2
-
19
-
-
3142579966
-
Identification of nucleophosmin as an NF-kappaB co-activator for the induction of the human SOD2 gene
-
Dhar SK, Lynn BC, Daosukho C, St Clair DK. Identification of nucleophosmin as an NF-kappaB co-activator for the induction of the human SOD2 gene. J Biol Chem 2004; 279: 28209-28219.
-
(2004)
J Biol Chem
, vol.279
, pp. 28209-28219
-
-
Dhar, S.K.1
Lynn, B.C.2
Daosukho, C.3
St Clair, D.K.4
-
20
-
-
0032757710
-
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia
-
van Dongen JJ, Macintyre EA, Gabert JA, Delabesse E, Rossi V, Saglio G et al. Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia. Leukemia 1999; 13: 1901-1928.
-
(1999)
Leukemia
, vol.13
, pp. 1901-1928
-
-
van Dongen, J.J.1
Macintyre, E.A.2
Gabert, J.A.3
Delabesse, E.4
Rossi, V.5
Saglio, G.6
-
21
-
-
27144501134
-
Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin
-
Quentmeier H, Martelli MP, Dirks WG, Bolli N, Liso A, Macleod RA et al. Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin. Leukemia 2005; 19: 1760-1767.
-
(2005)
Leukemia
, vol.19
, pp. 1760-1767
-
-
Quentmeier, H.1
Martelli, M.P.2
Dirks, W.G.3
Bolli, N.4
Liso, A.5
Macleod, R.A.6
-
22
-
-
33644968734
-
The NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance
-
Cilloni D, Messa F, Arruga F, Defilippi I, Morotti A, Messa E et al The NF-kappaB pathway blockade by the IKK inhibitor PS1145 can overcome Imatinib resistance. Leukemia 2007; 20: 61-67.
-
(2007)
Leukemia
, vol.20
, pp. 61-67
-
-
Cilloni, D.1
Messa, F.2
Arruga, F.3
Defilippi, I.4
Morotti, A.5
Messa, E.6
-
23
-
-
33846876123
-
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): Biologic and clinical features
-
Falini B, Nicoletti I, Martelli MF, Mecucci C. Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): Biologic and clinical features. Blood 2007; 109: 874-885.
-
(2007)
Blood
, vol.109
, pp. 874-885
-
-
Falini, B.1
Nicoletti, I.2
Martelli, M.F.3
Mecucci, C.4
-
24
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within cancer
-
Aggarwall BB. Nuclear factor-kappaB: The enemy within cancer. Cancer Cell 2004; 6: 203-208.
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwall, B.B.1
-
25
-
-
0037675869
-
NF-kappaB-dependent induction of cyclin D1 by retinoblastoma protein (pRB) family proteins and tumor derived pRB mutants
-
Takebayashi T, Higashi H, Sudo H, Ozawa H, Suzuki E, Shirado O et al NF-kappaB-dependent induction of cyclin D1 by retinoblastoma protein (pRB) family proteins and tumor derived pRB mutants. J Biol Chem 2003; 278: 14897-14905.
-
(2003)
J Biol Chem
, vol.278
, pp. 14897-14905
-
-
Takebayashi, T.1
Higashi, H.2
Sudo, H.3
Ozawa, H.4
Suzuki, E.5
Shirado, O.6
-
26
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: From innocent bystander to major culprit. Nat Rev Cancer 2002; 2: 301-310.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
27
-
-
0346505340
-
The IKK NF-κB system: A treasure trove for drug development
-
Karin M, Yamamoto Y, Wang QM. The IKK NF-κB system: A treasure trove for drug development. Nat Rev 2004; 3: 17-26.
-
(2004)
Nat Rev
, vol.3
, pp. 17-26
-
-
Karin, M.1
Yamamoto, Y.2
Wang, Q.M.3
-
28
-
-
19944427042
-
Targeting NF-kappaB activation via pharmacologic inhibition of IKK2 induced apoptosis of human acute myeloid leukaemia cells
-
Frelin C, Imbert V, Griessinger E. Peyron AC, Rochet N. Philip P et al. Targeting NF-kappaB activation via pharmacologic inhibition of IKK2 induced apoptosis of human acute myeloid leukaemia cells. Blood 2005; 105: 804-811.
-
(2005)
Blood
, vol.105
, pp. 804-811
-
-
Frelin, C.1
Imbert, V.2
Griessinger, E.3
Peyron, A.C.4
Rochet, N.5
Philip, P.6
-
29
-
-
36348988506
-
Nuclear factor kappakappaB as a target for new drug development in myeloid malignancies
-
Cilloni D, Martinelli G, Messa F, Baccarani M, Saglio G. Nuclear factor kappakappaB as a target for new drug development in myeloid malignancies. Haematologica 2007; 92: 1224-1229.
-
(2007)
Haematologica
, vol.92
, pp. 1224-1229
-
-
Cilloni, D.1
Martinelli, G.2
Messa, F.3
Baccarani, M.4
Saglio, G.5
-
30
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective anti-tumor agents
-
Adams J, Palombella VJ, Sausville EA, Johnson J, Destree A, Lazarus DD et al. Proteasome inhibitors: A novel class of potent and effective anti-tumor agents. Cancer Res 1999; 59: 2615-2622.
-
(1999)
Cancer Res
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
|