Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations

FEBS Journal

Volumn 275, Issue 13, 2008, Pages 3375-3387

  Jensen, Frank B ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Deoxyhemoglobin; Nitric oxide; Nitrite; Nitrosylhemoglobin; Oxyhemoglobin

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEOXYHEMOGLOBIN; HEMOGLOBIN; METHEMOGLOBIN; NITRIC OXIDE; NITRITE; OXYHEMOGLOBIN;

ANIMAL EXPERIMENT; ARTICLE; CARP; CONTROLLED STUDY; HYPOXIA; NONHUMAN; OXYGEN AFFINITY; OXYGEN SATURATION; OXYGEN TENSION; PRIORITY JOURNAL; RABBIT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOCHEMISTRY; CARPS; HEMOGLOBINS; MODELS, CHEMICAL; NITRIC OXIDE; NITRITE REDUCTASES; NITRITES; OXYGEN; OXYGEN CONSUMPTION; OXYHEMOGLOBINS; RABBITS; SPECIES SPECIFICITY; TIME FACTORS;

CYPRINIDAE; ORYCTOLAGUS CUNICULUS;

EID: 44949238560     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06486.x     Document Type: Article

References (35)

1. Kleinbongard P, Dejam A, Lauer T, Rassaf T, Schindler A, Picker O, Scheeren T, Gödecke A, Schrader J, Schulz R et al. (2003) Plasma nitrite reflects constitutive nitric oxide synthase activity in mammals. Free Radic Biol Med 35, 790 796.
2. Lundberg JO Weitzberg E (2005) NO generation from nitrite and its role in vascular control. Arterioscler Thromb Vasc Biol 25, 915 922.
3. Jensen FB (2003) Nitrite disrupts multiple physiological functions in aquatic animals. Comp Biochem Physiol 135A, 9 24.
4. Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X et al. (2003) Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med 9, 1498 1505.
5. Gladwin MT, Schechter AN, Kim-Shapiro DB, Patel RP, Hogg N, Shiva S, Cannon RO, Kelm M, Wink DA, Espey GE et al. (2005) The emerging biology of the nitrite anion. Nat Chem Biol 1, 308 314.
6. Zweier JL, Samouilov A Kuppusamy P (1999) Non-enzymatic nitric oxide synthesis in biological systems. Biochim Biophys Acta 1411, 250 262.
7. Millar TM, Stevens CR, Benjamin N, Eisenthal R, Harrison R Blake DR (1998) Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. FEBS Lett 427, 225 228.
8. Kozlov AV, Staniek K Nohl H (1999) Nitrite reductase activity is a novel function of mammalian mitochondria. FEBS Lett 454, 127 130.
9. Nagababu E, Ramasamy S, Abernethy DR Rifkind JM (2003) Active nitric oxide produced in the red cell under hypoxic conditions by deoxyhemoglobin- mediated nitrite reduction. J Biol Chem 278, 46349 46356.
10. Reutov VP (2002) Nitric oxide cycle in mammals and the cyclicity principle. Biochemistry (Mosc.) 67, 293 311.
11. Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH, Xu X, Murphy E, Darley-Usmar VM Gladwin MT (2007) Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circ Res 100, 654 661.
12. Crawford JH, Isbell TS, Huang Z, Shiva S, Chacko BK, Schechter AN, Darley-Usmar VM, Kerby JD, Lang JD Jr., Kraus D et al. (2006) Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood 107, 566 574.
13. Rifkind JM, Nagababu E, Barbiro-Michaely E, Ramasamy S, Pluta RM Mayevsky A (2007) Nitrite infusion increases cerebral blood flow and decreases mean arterial blood pressure in rats: a role for red cell NO. Nitric Oxide 16, 448 456.
14. Isbell TS, Gladwin MT Patel RP (2007) Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays. Am J Heart Circ Physiol 293, H2565 H2572.
15. Kosaka H Tyuma I (1987) Mechanism of autocatalytic oxidation of oxyhemoglobin by nitrite. Environ Health Perspect 73, 147 151.
16. Spagnuolo C, Rinelli P, Coletta M, Chiancone E Ascoli F (1987) Oxidation reaction of human oxyhaemoglobin with nitrite: a reexamination. Biochim Biophys Acta 911, 59 65.
17. Kim-Shapiro DB, Gladwin MT, Patel RP Hogg N (2005) The reaction between nitrite and hemoglobin: the role of nitrite in hemoglobin-mediated hypoxic vasodilation. J Inorg Biochem 99, 237 246.
18. Doyle MP, Pickering RA, DeWeert TM, Hoekstra JW Pater D (1981) Kinetics and mechanism of the oxidation of human deoxyhemoglobin by nitrites. J Biol Chem 256, 12393 12398.
19. Huang Z, Shiva S, Kim-Shapiro DB, Patel RP, Ringwood LA, Irby CE, Huang KT, Ho C, Hogg N, Schechter AN et al. (2005) Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest 115, 2099 2107.
20. Grubina R, Huang Z, Shiva S, Joshi MS, Azarov I, Basu S, Ringwood LA, Jiang A, Hogg N, Kim-Shapiro DB et al. (2007) Concerted nitric oxide formation and release from the simultaneous reactions of nitrite with deoxy- and oxyhemoglobin. J Biol Chem 282, 12916 12927.
21. 2 transport. Acta Physiol Scand 182, 215 227.
22. Jensen FB (2007) Nitric oxide formation from nitrite in zebrafish. J Exp Biol 210, 3387 3394.
23. Kiese M (1974) Methemoglobinemia: A Comprehensive Treatise. CRC Press, Cleveland, OH.
24. Jensen FB (1990) Nitrite and red cell function in carp: control factors for nitrite entry, membrane potassium ion permeation, oxygen affinity and methaemoglobin formation. J Exp Biol 152, 149 166.
25. Huang KT, Keszler A, Patel N, Patel RP, Gladwin MT, Kim-Shapiro DB Hogg N (2005) The reaction between nitrite and deoxyhemoglobin: reassessment of reaction kinetics and stoichiometry. J Biol Chem 280, 31126 31131.
26. Nagababu E, Ramasamy S Rifkind JM (2007) Intermediates detected by visible spectroscopy during the reaction of nitrite with deoxyhemoglobin: the effect of nitrite concentration and diphosphoglycerate. Biochemistry 46, 11650 11659.
27. Taboy CH, Faulkner KM, Kraiter D, Bonaventura C Crumbliss AL (2000) Concentration-dependent effects of anions on the anaerobic oxidation of hemoglobin and myoglobin. J Biol Chem 275, 39048 39054.
28. 0 and hemoglobin S. Implications for interactions of nitric oxide with normal and sickle red blood cells. J Biol Chem 277, 14557 14563.
29. Luchsinger BP, Rich EN, Yan Y, Williams EM, Stamler JS Singel DJ (2005) Assessments of the chemistry and vasodilatory activity of nitrite with haemoglobin under physiologically relevant conditions. J Inorg Biochem 99, 912 921.
30. Herold S Röck G (2005) Mechanistic studies of the oxygen-mediated oxidation of nitrosylhemoglobin. Biochemistry 44, 6223 6231.
31. Singel DJ Stamler JS (2005) Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol 67, 99 145.
32. Kleinschmidt T Sgouros JG (1987) Hemoglobin sequences. Biol Chem Hoppe-Seyler 368, 579 615.
33. Gladwin MT, Raat NJH, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB Patel RP (2006) Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signalling, cytoprotection, and vasodilation. Am J Physiol Heart Circ Physiol 291, H2026 H2035.
34. Robinson JM Lancaster JR Jr. (2005) Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide. Am J Respir Cell Mol Biol 32, 257 261.
35. Weber RE Jensen FB (1988) Functional adaptations in hemoglobins from ectothermic vertebrates. Annu Rev Physiol 50, 161 179.