Polyamine-polycarboxylate metal complexes with different biological effectiveness as nitric oxide scavengers. Clues for drug design

Journal of Medicinal Chemistry

Volumn 51, Issue 11, 2008, Pages 3250-3260

  Bambagioni, Valentina ^a   Bani, Daniele ^a   Bencini, Andrea ^a   Biver, Tarita ^b   Cantore, Miriam ^a   Chelli, Riccardo ^a   Cinci, Lorenzo ^a   Failli, Paola ^a   Ghezzi, Lisa ^b   Giorgi, Claudia ^a   Nappini, Silvia ^a   Secco, Fernando ^b   Tinè, Maria Rosaria ^b   Valtancoli, Barbara ^a   Venturini, Marcella ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID; ETHYLENE BISGLYCOL TETRAACETIC ACID; IRON COMPLEX; LIGAND; MANGANESE; METAL COMPLEX; N (2 HYDROXYETHYL) ETHYLENEDIAMINE N,N',N' TRIACETIC ACID; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; POLYAMINE; RUTHENIUM COMPLEX; SCAVENGER;

AB INITIO CALCULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; MACROPHAGE; MOUSE; NONHUMAN; POTENTIOMETRY; SEPTIC SHOCK; SPECTROPHOTOMETRY; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANIMALS; CELL LINE; CHELATING AGENTS; COBALT; CRYSTALLOGRAPHY, X-RAY; EDETIC ACID; EGTAZIC ACID; IRON; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MANGANESE; MICE; MODELS, MOLECULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; POTENTIOMETRY; RUTHENIUM; S-NITROSO-N-ACETYLPENICILLAMINE; SHOCK; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 44949222483     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm701553u     Document Type: Article

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