Iron chelates bind nitric oxide and decrease mortality in an experimental model of septic shock

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 17, 1996, Pages 9138-9141

  Kazmierski, Wieslaw M ^a,e   Wolberg, Gerald ^b   Wilson, Joan G ^b   Smith, Sheila R ^c   Williams, Darryl S ^c   Thorp, H Holden ^c   Molina, Luis ^d  

^a Division of Chemistry   (United States)

^b Division of Experimental Therapy   (United States)

^c University of North Carolina at Chapel Hill   (United States)

^d Molichem Medicines   (United States)

^e GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; FERRIOXAMINE; IRON CHELATE; IRON COMPLEX; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PENTETIC ACID; SCAVENGER;

ANIMAL MODEL; ARTICLE; CATALYSIS; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; DRUG MECHANISM; ELECTROCHEMISTRY; IRON CHELATION; MALE; MORTALITY; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SEPTIC SHOCK;

ANIMALS; CORYNEBACTERIUM INFECTIONS; DEFEROXAMINE; ELECTRIC CONDUCTIVITY; FERRIC COMPOUNDS; IRON CHELATING AGENTS; MALE; MICE; NITRIC OXIDE; PENTETIC ACID; PROPIONIBACTERIUM ACNES; SHOCK, SEPTIC;

ANIMALIA; BACTERIA (MICROORGANISMS); CORYNEBACTERIUM PARVUM;

EID: 0029831073     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.17.9138     Document Type: Article

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