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Volumn 158, Issue 6, 2008, Pages 793-801

Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; MESSENGER RNA; METFORMIN; ROSIGLITAZONE; TESTOSTERONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANDROGEN; ANTIDIABETIC AGENT;

EID: 44949152536     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/EJE-07-0857     Document Type: Article
Times cited : (41)

References (56)
  • 3
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W & Dobrjansky A. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 1989 38 1165.
    • (1989) Diabetes , vol.38 , pp. 1165
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 4
    • 0031787388 scopus 로고    scopus 로고
    • A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome
    • Legro RS, Finegood D & Dunaif A. A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 1998 83 2694-2698.
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , pp. 2694-2698
    • Legro, R.S.1    Finegood, D.2    Dunaif, A.3
  • 8
    • 0026699302 scopus 로고
    • Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome
    • Dunaif A, Segal KR, Shelley DR, Green G, Dobrjansky A & Licholai T. Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes 1992 41 1257-1266.
    • (1992) Diabetes , vol.41 , pp. 1257-1266
    • Dunaif, A.1    Segal, K.R.2    Shelley, D.R.3    Green, G.4    Dobrjansky, A.5    Licholai, T.6
  • 10
    • 0029119085 scopus 로고
    • Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome
    • Dunaif A, Xia J, Book CB, Schenker E & Tang Z. Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome. Journal of Clinical Investigations 1995 96 801-810.
    • (1995) Journal of Clinical Investigations , vol.96 , pp. 801-810
    • Dunaif, A.1    Xia, J.2    Book, C.B.3    Schenker, E.4    Tang, Z.5
  • 13
    • 0027450302 scopus 로고
    • Insulin resistance in polycystic ovary syndrome: Decreased expression of GLUT-4 glucose transporters in adipocytes
    • Rosenbaum D, Haber RS & Dunaif A. Insulin resistance in polycystic ovary syndrome: decreased expression of GLUT-4 glucose transporters in adipocytes. American Journal of Physiology 1993 264 197-202.
    • (1993) American Journal of Physiology , vol.264 , pp. 197-202
    • Rosenbaum, D.1    Haber, R.S.2    Dunaif, A.3
  • 14
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
    • Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocrine Reviews 1997 18 774-800.
    • (1997) Endocrine Reviews , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 16
    • 0034892698 scopus 로고    scopus 로고
    • Metformin directly inhibits androgen production in human thecal cells
    • Attia GR, Rainey WE & Carr BR. Metformin directly inhibits androgen production in human thecal cells. Fertility and Sterility 2001 76 517-524.
    • (2001) Fertility and Sterility , vol.76 , pp. 517-524
    • Attia, G.R.1    Rainey, W.E.2    Carr, B.R.3
  • 18
    • 34248593022 scopus 로고    scopus 로고
    • Effects of metformin treatment in women with polycystic ovary syndrome depends on insulin resistance
    • Nawrocka J & Starczewski A. Effects of metformin treatment in women with polycystic ovary syndrome depends on insulin resistance. Gynecological Endocrinology 2007 23 231-237.
    • (2007) Gynecological Endocrinology , vol.23 , pp. 231-237
    • Nawrocka, J.1    Starczewski, A.2
  • 19
    • 0038392806 scopus 로고    scopus 로고
    • Descriptive review of the evidence for the use of metformin in polycystic ovary syndrome
    • Harborne L, Fleming R, Lyall H, Norman J & Sattar N. Descriptive review of the evidence for the use of metformin in polycystic ovary syndrome. Lancet 2003 361 1894-1901.
    • (2003) Lancet , vol.361 , pp. 1894-1901
    • Harborne, L.1    Fleming, R.2    Lyall, H.3    Norman, J.4    Sattar, N.5
  • 20
    • 0142247208 scopus 로고    scopus 로고
    • Metformin in polycystic ovary syndrome: Systematic review and meta-analysis
    • Lord JM, Flinght IH & Norman RJ. Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMI 2003 327 951-953.
    • (2003) BMI , vol.327 , pp. 951-953
    • Lord, J.M.1    Flinght, I.H.2    Norman, R.J.3
  • 22
    • 34447096147 scopus 로고    scopus 로고
    • Metformin versus oral contraceptive pill in polycystic ovary syndrome: A Cochrane review
    • Costello MF, Shrestha B, Eden J, Johnson NP & Sjoblom P. Metformin versus oral contraceptive pill in polycystic ovary syndrome: a Cochrane review. Human Reproduction 2007 22 1200-1209.
    • (2007) Human Reproduction , vol.22 , pp. 1200-1209
    • Costello, M.F.1    Shrestha, B.2    Eden, J.3    Johnson, N.P.4    Sjoblom, P.5
  • 25
    • 29144477303 scopus 로고    scopus 로고
    • Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study
    • Tang T, Glanville J, Hayden CJ, White D, Barth JH & Balen AH. Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study. Human Reproduction 2006 21 80-89.
    • (2006) Human Reproduction , vol.21 , pp. 80-89
    • Tang, T.1    Glanville, J.2    Hayden, C.J.3    White, D.4    Barth, J.H.5    Balen, A.H.6
  • 27
    • 0002861937 scopus 로고    scopus 로고
    • Free fatty acids - do they play a central role in type 2 diabetes?
    • Arner P. Free fatty acids - do they play a central role in type 2 diabetes? Diabetes, Obesity and Metabolism 2001 3 S11-S19.
    • (2001) Diabetes, Obesity and Metabolism , vol.3
    • Arner, P.1
  • 31
    • 0002893369 scopus 로고    scopus 로고
    • The endocrine of obesity in eumenorrheic women
    • Eds R Azziz, JE Nestler & D Dewailly, Philadelphia: Lippincott- Raven Publishers
    • Pasquali R. The endocrine of obesity in eumenorrheic women. In Androgen Excess Disorders in Women, pp 507-518. Eds R Azziz, JE Nestler & D Dewailly, Philadelphia: Lippincott- Raven Publishers, 1997.
    • (1997) Androgen Excess Disorders in Women , pp. 507-518
    • Pasquali, R.1
  • 32
    • 0029795871 scopus 로고    scopus 로고
    • The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome
    • Dunaif A, Scott D, Finegood D, Quintana B & Whitcomb R. The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 1996 81 3299-3306.
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , pp. 3299-3306
    • Dunaif, A.1    Scott, D.2    Finegood, D.3    Quintana, B.4    Whitcomb, R.5
  • 33
    • 0035041906 scopus 로고    scopus 로고
    • Azziz R, Ehrmann D, Legro RS, Whitcomb RW, Hanley R, Fereshetian AG, O'Keefe M & Ghazzi MN. PCOS/Troglitazone Study Group. Troglitazone improves ovulation and hirsutism in the potycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial. Journal of Clinical Endocrinology and Metabolism 2001 86 1626-1632.
    • Azziz R, Ehrmann D, Legro RS, Whitcomb RW, Hanley R, Fereshetian AG, O'Keefe M & Ghazzi MN. PCOS/Troglitazone Study Group. Troglitazone improves ovulation and hirsutism in the potycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial. Journal of Clinical Endocrinology and Metabolism 2001 86 1626-1632.
  • 34
    • 0037380581 scopus 로고    scopus 로고
    • Azziz R, Ehrmann DA, Legro RS, Fereshetian AG, O'Keefe M & Ghazzi MN. PCOS/Troglitazone Study Group. Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome. Fertility and Sterility 2003 79 932-937.
    • Azziz R, Ehrmann DA, Legro RS, Fereshetian AG, O'Keefe M & Ghazzi MN. PCOS/Troglitazone Study Group. Troglitazone decreases adrenal androgen levels in women with polycystic ovary syndrome. Fertility and Sterility 2003 79 932-937.
  • 35
    • 0034755129 scopus 로고    scopus 로고
    • Improvement in insulin sensitivity followed by ovulation and pregnancy in a woman with polycystic ovary syndrome who was treated with rosiglitazone
    • Cataldo NA, Abbasi F, McLaughlin TL, Lamendola C & Reaven GM. Improvement in insulin sensitivity followed by ovulation and pregnancy in a woman with polycystic ovary syndrome who was treated with rosiglitazone. Fertility and Sterility 2001 76 1057-1059.
    • (2001) Fertility and Sterility , vol.76 , pp. 1057-1059
    • Cataldo, N.A.1    Abbasi, F.2    McLaughlin, T.L.3    Lamendola, C.4    Reaven, G.M.5
  • 36
    • 0037336327 scopus 로고    scopus 로고
    • Effect of rosiglitazone on spontaneous and clomiphene citrate-induced ovulation in women with polycystic ovary syndrome
    • Ghazeeri G, Kutteh WH, Bryer-Ash M, Haas D & Ke RW. Effect of rosiglitazone on spontaneous and clomiphene citrate-induced ovulation in women with polycystic ovary syndrome. Fertility and Sterility 2003 79 562-566.
    • (2003) Fertility and Sterility , vol.79 , pp. 562-566
    • Ghazeeri, G.1    Kutteh, W.H.2    Bryer-Ash, M.3    Haas, D.4    Ke, R.W.5
  • 37
    • 12244251426 scopus 로고    scopus 로고
    • Effects of rosiglitazone in obese women with polycystic ovary syndrome and severe insulin resistance
    • Sepilian V & Nagamani M. Effects of rosiglitazone in obese women with polycystic ovary syndrome and severe insulin resistance. Journal of Clinical Endocrinology and Metabolism 2005 90 60-65.
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , pp. 60-65
    • Sepilian, V.1    Nagamani, M.2
  • 38
    • 29144444654 scopus 로고    scopus 로고
    • Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome
    • Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice LC & Reaven GM. Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome. Human Reproduction 2006 21 109-120.
    • (2006) Human Reproduction , vol.21 , pp. 109-120
    • Cataldo, N.A.1    Abbasi, F.2    McLaughlin, T.L.3    Basina, M.4    Fechner, P.Y.5    Giudice, L.C.6    Reaven, G.M.7
  • 39
    • 33749035259 scopus 로고    scopus 로고
    • Endocrine and metabolic effects of rosiglitazone in overweight women with PCOS: A randomized placebo-controlled study
    • Rautio K, Tapanainen JS, Ruokonen A & Morin-Papunen LC. Endocrine and metabolic effects of rosiglitazone in overweight women with PCOS: a randomized placebo-controlled study. Human Reproduction 2006 21 1400-1407.
    • (2006) Human Reproduction , vol.21 , pp. 1400-1407
    • Rautio, K.1    Tapanainen, J.S.2    Ruokonen, A.3    Morin-Papunen, L.C.4
  • 41
    • 0001217801 scopus 로고
    • Diagnostic criteria for polycystic ovary syndrome
    • Eds A Dunaif, F Haseltine & GR Merriam, Boston: Blackwell Scientific Publications
    • Zawadzki JK & Dunaif A. Diagnostic criteria for polycystic ovary syndrome. In Polycystic Ovary Syndrome, pp 377-384. Eds A Dunaif, F Haseltine & GR Merriam, Boston: Blackwell Scientific Publications, 1992.
    • (1992) Polycystic Ovary Syndrome , pp. 377-384
    • Zawadzki, J.K.1    Dunaif, A.2
  • 42
    • 77951697875 scopus 로고    scopus 로고
    • Definition, diagnosis, and epidemiology of the polycystic ovary syndrome
    • Ed, New York: Springer Science, Business Media, LCC
    • Azziz R. Definition, diagnosis, and epidemiology of the polycystic ovary syndrome. In The Polycystic Ovary Syndrome: Current Concepts on Pathogenesis and Clinical Care, p 5. Ed. R Azziz, New York: Springer Science + Business Media, LCC, 2007.
    • (2007) The Polycystic Ovary Syndrome: Current Concepts on Pathogenesis and Clinical Care , pp. 5
    • Azziz, R.1
  • 43
    • 0035195629 scopus 로고    scopus 로고
    • Subcutaneous abdominal, but not femoral fat expression of plasminogen activator inhibitor-1 (PAI-I) is related to plasma PAI-1 levels and insulin resistance and decreases after weight loss
    • Mavri A, Alessi MC, Bastelica D, Geel-Georgelin O, Fina F, Sentocnik IT, Stegnar M & Juhan-Vague I. Subcutaneous abdominal, but not femoral fat expression of plasminogen activator inhibitor-1 (PAI-I) is related to plasma PAI-1 levels and insulin resistance and decreases after weight loss. Diabetologia 2001 44 2025-2031.
    • (2001) Diabetologia , vol.44 , pp. 2025-2031
    • Mavri, A.1    Alessi, M.C.2    Bastelica, D.3    Geel-Georgelin, O.4    Fina, F.5    Sentocnik, I.T.6    Stegnar, M.7    Juhan-Vague, I.8
  • 44
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 45
    • 0034061181 scopus 로고    scopus 로고
    • Relation between insulin resistance and carotid intima-media thickness and stenosis in non-diabetic subjects. Results from a cross-sectional study in Malmo, Sweden
    • Hedblad B, Nilsson P, Janzon L & Berglund G. Relation between insulin resistance and carotid intima-media thickness and stenosis in non-diabetic subjects. Results from a cross-sectional study in Malmo, Sweden. Diabetic Medicine 2000 17 299-307.
    • (2000) Diabetic Medicine , vol.17 , pp. 299-307
    • Hedblad, B.1    Nilsson, P.2    Janzon, L.3    Berglund, G.4
  • 46
    • 5144220551 scopus 로고    scopus 로고
    • Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity
    • Baillargeon JP, Jakubowicz DJ, Iuorno MJ, Jakubowicz S & Nestler JE. Effects of metformin and rosiglitazone, alone and in combination, in nonobese women with polycystic ovary syndrome and normal indices of insulin sensitivity. Fertility and Sterility 2004 82893-902.
    • (2004) Fertility and Sterility , pp. 82893-82902
    • Baillargeon, J.P.1    Jakubowicz, D.J.2    Iuorno, M.J.3    Jakubowicz, S.4    Nestler, J.E.5
  • 49
    • 34347362939 scopus 로고    scopus 로고
    • Metformin and glitazones: Do they really help PCOS patients?
    • Pillai A, Bang H & Green C. Metformin and glitazones: do they really help PCOS patients? Journal of Family Practice 2007 56 444-453.
    • (2007) Journal of Family Practice , vol.56 , pp. 444-453
    • Pillai, A.1    Bang, H.2    Green, C.3
  • 51
    • 0037302009 scopus 로고    scopus 로고
    • Reduced production rates of testosterone and dihydrotestosterone in healthy men treated with rosiglitazone
    • Vierhapper H, Nowomy P & Waldhausl W. Reduced production rates of testosterone and dihydrotestosterone in healthy men treated with rosiglitazone. Metabolism 2003 52 230-232.
    • (2003) Metabolism , vol.52 , pp. 230-232
    • Vierhapper, H.1    Nowomy, P.2    Waldhausl, W.3
  • 54
    • 0035907330 scopus 로고    scopus 로고
    • Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 39-hydroxysteroid dohydrogenase
    • Arlt W Auchus RJ & Miller WL. Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 39-hydroxysteroid dohydrogenase. Journal of Biological Chemistry 2001 276 16767-16771.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 16767-16771
    • Arlt, W.1    Auchus, R.J.2    Miller, W.L.3
  • 55
    • 0033963473 scopus 로고    scopus 로고
    • Metformin treatment reduces ovarian cytochrome P-450c17alpha response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome
    • la Marca A, Egbe TO, Morgante G, Paglia T, Cianci A & De Leo V Metformin treatment reduces ovarian cytochrome P-450c17alpha response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome. Human Reproduction 2000 15 21-23.
    • (2000) Human Reproduction , vol.15 , pp. 21-23
    • la Marca, A.1    Egbe, T.O.2    Morgante, G.3    Paglia, T.4    Cianci, A.5    De Leo, V.6
  • 56
    • 45249092382 scopus 로고    scopus 로고
    • Strategies for ovulation induction in the management of anovulatory polycystic ovary syndrome
    • Ed, New York: Springer Science, Business Media, LCC
    • Balen A. Strategies for ovulation induction in the management of anovulatory polycystic ovary syndrome. In The Polycystic Ovary Syndrome: Current Concepts on Pathogenesis and Clinical Care, p 110. Ed. R Azziz, New York: Springer Science + Business Media, LCC, 2007.
    • (2007) The Polycystic Ovary Syndrome: Current Concepts on Pathogenesis and Clinical Care , pp. 110
    • Balen, A.1


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