Coherent optical imaging and guided interventions in breast cancer: Translating technology into clinical applications

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 6991, Issue , 2008, Pages

  Boppart, Stephen A ^a,c,e,f   Nguyen, Freddy T ^a,b,d   Zysk, Adam M ^a,b   Chaney, Eric J ^a,b   Kotynek, Jan G ^e,f   Oliphant, Uretz J ^e,f   Bellafiore, Frank J ^e,f   Rowland, Kendrith M ^e,f   Johnson, Patricia A ^e,f  

^a Biophotonics Imaging Laboratory   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c University of Illinois at Urbana Champaign   (United States)

^d Medical Scholars Program   (United States)

^e UNIVERSITY OF ILLINOIS   (United States)

^f CARLE FOUNDATION HOSPITAL   (United States)

Author keywords

Biomedical optics; Breast cancer; Clinical imaging; Image guided surgery; Lymph node; Metastasis; Optical coherence tomography

Indexed keywords

BODY FLUIDS; CELLS; COHERENT LIGHT; COMPUTER NETWORKS; DECISION MAKING; DIAGNOSTIC RADIOGRAPHY; ELECTROACUPUNCTURE; HEALTH; HEALTH CARE; MEDICAL IMAGING; NANOSTRUCTURED MATERIALS; OPTICAL IMAGE STORAGE; OPTICAL TESTING; OPTICAL TOMOGRAPHY; OPTICS; PLANNING; RESOURCE ALLOCATION; SOFTWARE TESTING; STANDARDS; SURGERY; TECHNOLOGY; THERMOGRAPHY (TEMPERATURE MEASUREMENT); TISSUE; TOMOGRAPHY; TRANSPLANTATION (SURGICAL); TUMORS;

(OTDR) TECHNOLOGY; APPLIED (CO); BIO PHOTONICS; BREAST CANCERS; BREAST TISSUES; CANCER CELLS; CLINICAL APPLICATIONS; COHERENT OPTICAL IMAGING; DIFFUSE OPTICAL TOMOGRAPHY (DOT); FEASIBILITY STUDIES; INTRA-OPERATIVE; LOW COHERENCE INTERFEROMETRY (LCI); LYMPH NODE (LN); LYMPHATIC SYSTEMS; NUMEROUS APPLICATIONS; OPTICAL MAMMOGRAPHY; OPTICAL-COHERENCE TOMOGRAPHY (OCT); PHOTONIC; PRE-CLINICAL TESTING; SURGICAL RESECTION; TUMOR CELLS; TUMOR MASS; X RAY MAMMOGRAPHY;

IMAGING TECHNIQUES;

EID: 44949144062     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.780168     Document Type: Conference Paper

References (22)

1. Cancer Facts &Figures 2008. American Cancer Society, 2008.
2. Breast Cancer Facts & Figures 2007-2008, American Cancer Society, 2008
3. rd, and Sclafani, L. M., "Influence of frozen-section analysis of sentinel lymph node and lumpectomy margin status on reoperation rates in patients undergoing breast-conserving therapy," J. Am. Coll. Surg. 206, 76-82 (2008).
4. Bakhshandeh, M., Tutuncuoglu, S. O., Fischer, G., and Masood, S., "Use of imprint cytology for assessment of surgical margins in lumpectomy specimens in breast cancer patients," Diagn. Cytopathol. 35, 656-659 (2007).
5. Clare, S. E., Sener, S. F., Wilkens, W., Goldschmidt, R., Merkel, D., and Winchester, D. J., "Prognostic significance of occult lymph node metastases in node-negative breast cancer," Ann. Surg. Oncol. 4, 447-451 (1997).
6. Cote, R. J., Peterson, H. F., Chaiwun, B., Gelber, R. D., Goldhirsch, A., Castiglione-Gertsch, M., Gusterson, B., and Neville, A. M., "Role of immunohistochemical detection of lymph-node metastases in management of breast cancer," Lancet 354, 896-900 (1999).
7. Boppart, S. A., Luo, W., Marks, D. L., and Singletary, K. W., "Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer," Breast Cancer Res. Treat. 84, 85-97 (2004).
8. Zysk, A. M. and Boppart, S. A., "Computational methods for analysis of human breast tumor tissue in optical coherence tomography images," J. Biomed. Opt. 11, 054015 (2006).
9. Zysk, A. M., Chaney, E. J., and Boppart, S. A., "Refractive index of carcinogen-induced rat mammary tumours," Phys. Med. Biol. 51, 2165-2177 (2006)
10. Zysk, A. M., Adie, S. G., Armstrong, J. J., Leigh, M. S., Paduch, A., Sampson, D. D., Nguyen, F. T., and Boppart, S. A., "Needle-based refractive index measurement using low coherence interferometry," Opt. Lett. 32, 385-387 (2007).
11. Hsiung, P. L., Phatak, D. R., Chen, Y., Aguirre, A, D., Fujimoto, J. G., and Connolly, J. L., "Benign and malignant lesions in the human breast depicted with ultrahigh resolution and three-dimensional optical coherence tomography," Radiology 244, 865-874 (2007).
12. Zysk, A. M., Nguyen, F. T., Oldenburg, A. L., Marks, D, L., and Boppart, S. A., "Optical coherence tomography: a review of clinical development from bench to bedside," J. Biomed. Opt. 12, 051403 (2007).
13. Nguyen, F. T., Zysk, A. M., Kotynek, J. G., Oliphant, U. J., Bellafiore, F. J., Rowland, K. M., Johnson, P. A., Chaney, E. J., and Boppart, S. A., "Real-time optical coherence tomography for the intraoperative microscopic assessment of surgical margins in breast cancer," Paper 6847-66, SPIE Proceedings, Photonics West - Biomedical Optics, San Jose, CA, January 19-24, 2008
14. Greene, F. L., Fleming, I. D., Fritz, A. G., Balch, C. M., Haller, D. G., and Morrow, M., eds., American Joint Committee on Cancer Staging Manual. 6th ed., New York, NY: Springer (2002).
15. Cancer Prevention & Early Detection Facts & Figures, American Cancer Society (2006).
16. Luo, W., Nguyen, F. T., Zysk, A. M., Ralston, T. S., Brockenbrough, J., Marks, D. L., Oldenburg, A. L, and Boppart, S. A., "Optical biopsy of lymph node morphology using optical coherence tomography," Technol. Cancer Res. Treat. 4, 539-548 (2005).
17. Nguyen, F. T., Zysk, A. M., Kotynek, J. G., Oliphant, U. J., Brockenbrough, J., Bellafiore, F. J., Rowland, K. M., Johnson, P. A., Chaney, E. J., and Boppart, S. A., "Real-time lymph node assessment using optical coherence tomography for the staging of breast cancer," Paper 6847-107, SPIE Proceedings, Photonics West -Biomedical Optics, San Jose, CA, January 19-24, 2008
18. Meeske, K. A., Sullivan-Halley, J., Smith, A. W., McTiernan, A., Baumgartner, K. B., Harlan, L. C., and Bernstein, L., "Risk factors for arm lymphedema following breast cancer diagnosis in black women and white women," Breast Cancer Res. Treat., eprint, February 24, 2008.
19. Zysk, A. M., Marks, D. L., Liu, D. Y., and Boppart, S. A., "Needle-based reflection refractometry of scattering samples using coherence-gated detection," Optics Express 15, 4787-4794 (2007).
20. Iftimia, N.V., Bouma, B. E., Pitman, M. B., Goldberg, B. Bressner, J., and Tearney, G. J., "A portable, low coherence interferometry based instrument for fine needle aspiration biopsy guidance," Rev. Sci. Instr. 76, 064301 (2005).
21. Goldberg, B. D., Iftimia, N. V., Bressner, J. E., Pitman, M. B., Halpern, E., Bouma, B. E., Tearney, G. J., "Automated algorithm for differentiation of human breast tissue using low coherence interferometry for fine needle aspiration biopsy guidance," J. Biomed. Opt. 13, 014014 (2008).
22. Ralston, T. S., Marks, D. L., Carney, P. S., and Boppart, S. A., "Interferometric synthetic aperture microscopy," Nature Physics 3, 129-134 (2007).