Peritoneal adhesions: Facing the enemy

International Journal of Surgery

Volumn 6, Issue 3, 2008, Pages 253-260

  Ergul, Emre ^a   Korukluoglu, Birol ^a  

^a ATATURK TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Post surgical intraperitoneal adhesions

Indexed keywords

ANTIBIOTIC PROPHYLAXIS; COST BENEFIT ANALYSIS; PATIENT SAFETY; PERITONEUM ADHESION; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; TISSUE INJURY;

ADHESIONS; ANIMALS; BIOCOMPATIBLE MATERIALS; GENE THERAPY; HEPATOCYTE GROWTH FACTOR; HUMANS; PERITONEAL DISEASES; PERITONEUM; PHARMACEUTICAL PREPARATIONS; POSTOPERATIVE COMPLICATIONS;

EID: 44849144014     PISSN: 17439191     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijsu.2007.05.010     Document Type: Review

References (121)

1. Menzies D., and Ellis H. Intestinal obstruction from adhesion: how big is the problem?. Ann R Coll Surg Engl 72 (1990) 60-63
2. Luijendijk R.W., de Lange D.C., Wauters C.C., Hop W.C., Duron J.J., Pailler J.L., et al. Foreign material in postoperative adhesions. Ann Surg 223 (1996) 242-248
3. Suslavich F.J., Turner N.A., King P.S., and Brown H.K. Intra-abdominal adhesions: intraoperative US. Radiology 172 (1989) 387-389
4. Monk B.J., Berman M.L., and Montz F.J. Adhesions after extensive gynecologic surgery: clinical significance, etiology and prevention. Am J Obstet Gynecol 170 (1994) 1396-1403
5. Luciano A.A. Prevention of postoperative adhesions. In: Nezhat C.R., Berger G.S., Nezhat F.R., et al. (Eds). Endometriosis: advanced management and surgical techniques (1995), Springer, New York 193-199
6. Scovill W. Small bowel obstruction. In: Cameron J.L. (Ed). Current therapy in surgery (1995), Mosby, St.Louis 100-104
7. Ellis H. The causes and prevention of intestinal adhesions. Br J Surg 69 5 (1982) 241-243
8. Hodgkin T. Lectures on the morbid anatomy of the serous and mucous membranes Vol 1 (1836), Simpkin Marshall and Co, London
9. Rokitansky C. A Manual of pathological anatomy Vol 2 (1849), Sydenham Society, London
10. Bryant T. Clinical Lectures on intestinal obstructions. Medical Times Gazette 1 (1872) 363
11. Gibson C.L. A study of 1000 operations for acute intestinal obstruction. Ann Surg 32 (1900) 486
12. Vick R.M. Statistics of acute intestinal obstruction. BMJ 2 (1932) 546
13. McEntee G., Pender D., Mulvin D., McCullough M., Naeeder S., Farah S., et al. Current spectrum of intestinal obstruction. Br J Surg 74 (1987) 976-980
14. Cox M.R., Gunn I.F., Eastman M.C., Hunt R.F., and Heinz A.W. The operative aetiology and types of adhesions causing small bowel obstruction. Aust N Z J Surg 63 (1993) 848-852
15. Soybel D.I. Ileus and bowel obstruction. In: Greenfield L.J. (Ed). Surgery: scientific principles and practice (1997), Lippincott-Raven, Philadelphia 817-831
16. Ellis H. The clinical significance of adhesions: focus on intestinal obstruction. Eur J Surg Suppl 557 (1997) 5-9
17. Menzies D. Peritoneal adhesions: incidence, cause, and prevention. Surg Annu Surg 24 (1992) 27-45
18. Stricker B., Blanco J., and Fox H.E. The gynecologic contribution to intestinal obstruction in females. J Am Coll Surg 178 (1994) 617-620
19. Wilkins B.M., and Spitz L. Incidence of postoperative adhesion obstruction following neonatal laparotomy. Br J Surg 73 (1986) 762-764
20. Solomkin J.S., Wittmann D.W., West M.A., and Barie P.F. Intra-abdominal infection. In: Schwartz S.L., Shires G.T., Spencer F.C., Daly J.M., Ficher J.E., and Galloway A.C. (Eds). Principles of surgery. 7th ed Vol 2 (1999), McGraw-Hill, New York 1515-1534
21. Trompke R., and Siegner R. Ein Beitrag zu den Verhütungsmabnahmen postoperativer interabdomineller Verwachsungen. Arch Klin Chir 281 (1956) 323
22. Buckman Jr. R.F., Buckman P.D., Hufnagel H.V., and Gervin A.S. A physiologic basis for the adhesion-free healing of deperitonealized surfaces. J Surg Res 21 (1976) 67
23. Drolette C.M., and Badawy S.Z.A. Pathophysiology of pelvic adhesions: modern trends in preventing infertility. J Reprod Med 37 (1992) 107-122
24. Di Zerega G.S. The peritoneum: postsurgical repair and adhesion formation. In: Rock J.A., Murphy A.A., and Jones H.W. (Eds). Female reproductive surgery (1992), Williams & Wilkins, Baltimore 2-18
25. Rodgers K.E., and di Zegera G.S. Functions of peritoneal exudate cells after abdominal surgery. J Invest Surg 6 (1993) 9-23
26. Di Zerega G.S. Biochemical events in peritoneal tissue repair. Eur J Surg Suppl 577 (1997) 10-16
27. Liakakos T., Thomakos N., Fine P.M., Dervenis C., and Young R.L. Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Dig Surg 18 (2001) 260-273
28. Saed G.M., and Diamond M.P. Differential expression of alpha smooth muscle cell actin in human fibroblasts isolated from intraperitoneal adhesions and normal peritoneal tissues. Fertil Steril 82 3 (2004) 1188-1192
29. Ellis H. The aetiology of post-operative abdominal adhesions: an experimental study. Br J Surg 50 (1962) 10
30. Buckman Jr. R.F., Buckman P.D., Hufnagel H.V., and Gervin A.S. A unifying pathogenetic mechanism in the etiology of intraperitoneal adhesions. J Surg Res 20 (1976) 1
31. Myhre-Jensen O., Larsen S.B., and Astrup T. Fibrinolytic activity in serosal and synovial membranes. Arch Pathol 20 (1969) 80
32. Porter J.M., McGregor Jr. F.H., Mullen D.C., and Silver D. Fibrinolytic activity of mesothelial surfaces. Surg Forum 88 (1969) 623
33. Raftery A.T. Regeneration of peritoneum: a fibrinolytic study. J Anat 129 (1979) 659
34. Raftery A.T. Effect of peritoneal trauma on peritoneal fibrinolytic activity and intraperitoneal adhesion formation. Eur Surg Res 13 (1981) 397
35. Gomel V., Urman B., and Gurgan T. Pathophysiology of adhesion formation and strategies for prevention. J Reprod Med 41 (1996) 35-41
36. Ryan G.B., Grobety J., and Majno G. Postoperative peritoneal adhesions. Am J Pathol 65 (1971) 117
37. Polubinska A., Winckiewicz M., Staniszewski R., Breborowicz A., and Oreopoulos D.G. Time to reconsider saline as the ideal rinsing solution during abdominal surgery. Am J Surg 192 (2006) 281-285
38. Weibel M.A., and Majno G. Peritoneal adhesions and their relation to abdominal surgery. Am J Surg 126 (1973) 345
39. Ellis H., Harrison W., and Hugh T.B. The healing of the peritoneum under normal and pathological conditions. Br J Surg 52 (1965) 471
40. Down R.H.L., Whitehead R., and Watts J.Mc.K. Do surgical packs cause peritoneal adhesions?. Aust NZ J Surg 49 (1979) 379
41. Holtz G. Adhesion induction by suture of varying tissue reactivity and caliber. Int J Fertil 27 (1982) 134
42. Holtz G. Prevention and management of peritoneal adhesions. Fertil Steril 41 4 (1984) 497-507
43. Sanfilippo J.S., Barrows G.H., and Yussman M.A. Comparison of Avitene, topical thrombin, and Gelfoam as sole haemostatic agents in tuboplasties. Fertil Steril 33 (1980) 660
44. Larsson B., Nisell H., and Grandberg I. Surgicel-an absorbable haemostatic material in prevention of peritoneal adhesions in rats. Acta Chir Scand 133 (1978) 375
45. Raftery A. Absorbable haemostatic materials and intraperitoneal adhesion formation. Br J Surg 67 (1980) 57
46. Tingstedt B., Nehez L., Lindman B., and Andersson R. Efficacy of bioactive polypeptides on bleeding and intra-abdominal adhesions. Eur Surg Res 39 1 (2007) 35-40
47. Goldberg E.P., Sheets J.W., and Habal M.B. Peritoneal adhesions: prevention with the use of hydrophilic polymer coatings. Arch Surg 115 (1980) 776
48. Diamond M.P., and De Cherney A.H. Pathogenesis of adhesion formation/reformation: application to reproductive pelvic surgery. Microsurgery 8 (1987) 103-107
49. Frankfurter D., and De Cherney A.H. Pelvic adhesive disease. Postgrade Obstet Gynecol 16 (1996) 1-5
50. Choe J.K., Dawood M.Y., and Andrews A.H. Conventional versus laser reanastomosis of rabbit ligated uterine horn. Obstet Gynecol 61 (1983) 689
51. 2 laser and electrocautery on postoperative intraperitoneal adhesion formation in rabbits. Fertil Steril 40 (1983) 366
52. Sutton C., and MacDonald R. Laser laparoscopic adhesiolysis. J Gynecol Surg 6 3 (1990) 155-159
53. Erdogan G., Prevention of postoperative intraperitoneal adhesions by Methylene blue, carboxymethyl cellulose with sodium hyaluronic acid [unpublished observation].
54. Phillips J.M. Gynecologic microsurgery, a déjà vu of laparoscopy. J Reprod Med 22 (1979) 135
55. Kothari S.N., Fundell L.J., Lambert P.J., and Mathiason M.A. Use of transabdominal ultrasound to identify intraabdominal adhesions prior to laparoscopy: a prospective blinded study. Am J Surg 192 (2006) 843-847
56. Kavic S.M., and Kavic S.M. Adhesions and adhesiolysis: the role of laparoscopy. JSLS 6 2 (2002) 99-109
57. Brokelman W.J., Holmdahl L., Bergstrom M., Falk P., Klinkenbijl J.H., and Reijnen M.M. Peritoneal fibrinolytic response to various aspects of laparoscopic surgery: a randomized trial. J Surg Res 136 2 (2006) 309-313
58. Di Zerega G.S. Contemporary adhesion prevention. Fertil Steril 61 (1994) 219-235
59. Risberg B.O. Adhesions: preventive strategies. Eur J Surg Suppl 577 (1997) 32-39
60. Gutmann J.N., Penzias A.S., and Diamond M.P. Adhesions in reproductive surgery. In: Wallach E.E., and Zaccur H.A. (Eds). Reproductive medicine and surgery (1995), Mosby, St. Louis 681-693
61. Sarr M.G., and Tito W.A. Intestinal obstruction. In: Zuidema G.D. (Ed). Shackelford's surgery of the alimentary tract. 4th ed Vol 5 (1996), WB Saunders Company, Philadelphia 387-389
62. Blauer K.L., and Collins R.L. The effect of intraperitoneal progesterone on postoperative adhesion formation in rabbits. Fertil Steril 49 1 (1988) 144-149
63. Tulandi T. Adhesion prevention in laparoscopic surgery. Int J Fertil Menopausal Stud 41 (1996) 452-457
64. Turkcapar A.G., Ozarslan C., Erdem E., Bumin C., Erverdi N., and Kutlay J. The effectiveness of LMWH on adhesion formation in experimental rat model. Int Surg 80 1 (1995) 92-94
65. Sahin Y., and Saglam A. Synergistic effects of carboxymethylcellulose a low molecular weight heparin in reducing adhesion formation in the rat uterine horn model. Acta Obstet Gynecol Scand 73 (1994) 70-73
66. Arikan S., Adas G., Barut G., Toklu A.S., Kocakusak A., Uzun H., et al. An evaluation of low molecular weight heparin and hyperbaric oxygen treatment in the prevention of intra-abdominal adhesions and wound healing. Am J Surg 189 (2005) 155-160
67. Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl 75 (1993) 147-153
68. Montz F.J., Fowler J.M., Wolff A.J., Lacey S.M., and Mohler M. The ability of recombinant plasminogen activator to inhibit post-radical pelvic surgery adhesion in the dog model. Am J Obstet Gynecol 43 (1991) 141-145
69. Thompson J.N., Paterson-Brown S., Harbourne T., Whawell S.A., Kalodiki E., and Dudley H.A. Reduced human peritoneal plasminogen activating activity: possible mechanism of adhesion formation. Br J Surg 76 (1989) 382-384
70. Doody K.J., Dunn R.C., and Buttram Jr. V.C. Recombinant tissue plasminogen activator reduces adhesion formation in a rabbit uterine horn model. Fertil Steril 51 (1989) 509-512
71. Sanfilippo J.S., Booth R.J., and Burns C.D. Effect of vitamin E on adhesion formation. J Repro Med 40 4 (1995) 278-282
72. de la Portilla F., Ynfante I., Bejarano D., Conde J., Fernandez A., Ortega J.M., et al. Prevention of peritoneal adhesions by intraperitoneal administration of vitamin E: an experimental study. Dis Colon Rectum 47 12 (2004) 2157-2161
73. Tokmak H., Tibet H.B., Balkanli M., Koksal O., and Aydin R. Postoperatif yapisikliklarin onlenmesinde vitamin E'nin sinerjistik etkileri. Turk J Surg 11 3 (1995) 162-167
74. Salaris S.C., Babbs C., and Voorhees III W.D. Methylene blue as an inhibitor of superoxide generation by xanthine oxidase. A potential new drug for the attenuation of ischemia/reperfusion injury. Biochem Pharmacol 42 3 (1991) 499-506
75. Kelner M.J., Bagnell R., Hale B., and Alexander N.M. Potential of methylene blue to block oxygen radical generation in reperfusion injury. Basic Life Sci 49 (1988) 895-898
76. Kelner M.J., Bagnell R., Hale B., and Alexander N.M. Methylene blue competes with paraquat for reduction by flavo-enzymes resulting in decreased superoxide production in the presence of heme proteins. Arch Biochem Biophys 262 2 (1988) 422-426
77. Ignarro L.J., and Kadowitz P.J. The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation. Annu Rev Pharmacol Toxicol 25 (1985) 171-191
78. Matsuoka I., Sakurai K., Ono T., and Nakanishi H. Involvement of endogenous noradrenaline release in Methylene blue induced contraction of isolated rabbit aorta. Jpn J Pharmacol 44 1 (1987) 23-33
79. Galili Y., Ben-Abraham R., Rabau M., Klausner J., and Kluger Y. Reduction of surgery-induced adhesions by Methylene blue. Am J Surg 175 (1998) 30-32
80. Kluger Y., Weinbroum A., Ben-Avraham R., Galili Y., Klausner J., and Rabau M. Reduction in formation of peritoneal adhesions by methylene blue in rats: a dose response study. Eur J Surg 166 (2000) 568-571
81. Cetin M., Ak D., Duran B., Cetin A., Guvenal T., and Yanar O. Use of methylene blue and N, O-carboxymethylchitosan to prevent postoperative adhesions in rat uterine horn model. Fertil Steril 80 (2003) 698-701
82. Dinc S., Ozaslan C., Kuru B., Karaca S., Ustun H., Alagol H., et al. Methylene blue prevents surgery-induced peritoneal adhesions but impairs the early phase of anastomotic wound healing. Can J Surg 49 5 (2006) 321-328
83. Jarret P.E., Moreland M., and Browse N.L. The effect of oxpentifylline ("Trental") on fibrinolytic activity and plasma fibrinogen levels. Curr Med Res Opin 4 (1977) 492-495
84. Schroer R.H. Antithrombotic potential of pentoxifylline. A hemorheologically active drug. Angiology 36 (1985) 387-398
85. Alkharfy K.M., Kellum J.A., and Matzke G.R. Unintended immunomodulation: part II. Effects of pharmacological agents on cytokine activity. Shock 13 (2000) 346-360
86. Tarhan O.R., Barut I., Sutcu R., Akdeniz Y., and Akturk O. Pentoxifylline, a methyl xanthine derivative, reduces peritoneal adhesions and increases peritoneal fibrinolysis in rats. Tohoku J Exp Med 209 (2006) 249-255
87. Aarons C.B., Cohen P.A., Gower A., Reed K.L., Leeman S.E., Stucchi A.F., et al. Statins (HMG-CoA Reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity. Ann Surg 245 2 (2007) 176-184
88. Holmdahl L. Making and covering of surgical footprints. Lancet 353 (1999) 1456-1457
89. Hosie K., Gilbert J.A., Kerr D., Brown C.B., and Peers E.M. Fluid dynamics in man of an intraperitoneal drug delivery solution: 4% Icodextrin. Drug Delivery 8 (2001) 9-12
90. Gilbert J.A., Peers E.M., and Brown C.B. Intraperitoneal fluid dynamics of 4% icodextrin in non-ESRD patients. Perit Dial Int 19 1 (1999) S79
91. diZerega G.S., Verco S.J., Young P., Kettel M., Kobak W., Martin D., et al. A randomized, controlled pilot study of the safety and efficacy of 4% icodextrin solution in the reduction of adhesions following laparoscopic gynecological surgery. Hum Reprod 7 (2002) 1031-1038
92. van den Tol P., ten Raa S., van Grevenstein H., Marquet R., van Eijck C., and Jeekel H. Icodextrin reduces postoperative adhesion formation in rats without affecting peritoneal metastasis. Surgery 137 (2005) 348-354
93. Wallwiener M., Brucker S., Hierlemann H., Brochhausen C., Solomayer E., and Wallwiener C. Innovative barriers for peritoneal adhesion prevention: liquid or solid? A rat uterine horn model. Fertil Steril 86 3 (2006) 1266-1276
94. Davies D. Kinetics of icodextrin. Perit Dial Int 14 2 (1994) 45-50
95. Belluco C., Meggiolaro F., Pressato D., Pavesio A., Bigon E., Dona M., et al. Prevention of postsurgical adhesions with an autocrosslinked hyaluronan derivate gel. J Surg Res 100 (2001) 217-221
96. Carta G., Cerrone L., and Iovenitti P. Postoperative adhesion prevention in gynecologic surgery with hyaluronic acid. Clin Exp Obstet Gynecol 31 (2004) 39-41
97. Burns J.W., Skinner K., Colt J., Sheidlin A., Bronson R., Yaacobi Y., et al. Prevention of tissue injury and postoperative adhesion by precoating tissues with hyaluronic acid solution. J Surg Res 59 (1995) 644-652
98. Martin-Cartes J.A., Morales-Conde S., Suarez-Grau J.M., Bustos-Jimenez M., Cadet-Dussort H., Socas-Macias M., et al. Prevention of peritoneal adhesions to intraperitoneal prostheses. An experimental study in pigs. Cir Esp 80 4 (2006) 214-219
99. Hills B.A. Role of surfactant in peritoneal dialysis. Perit Dial Int 20 (2000) 503-515
100. Ar'Rajab A., Snoj M., Larsson K., and Bengmark S. Exogenous phospholipid reduces postoperative peritoneal adhesions in rats. Eur J Surg 161 (1995) 341-344
101. Snoj M., Ar'Rajab A., Ahren B., and Bengmark S. Effect of phosphatidylcholine on postoperative adhesions after small bowel anastamosis in the rat. Br J Surg 79 (1992) 427-429
102. Snoj M., Ar'Rajab A., Ahren B., Larsson K., and Bengmark S. Phospholipase-resistant phosphatidylcholine reduces intra-abdominal adhesions induced by bacterial peritonitis. Res Exp Med (Berl) 193 (1993) 177-222
103. Muller S.A., Treutner K.H., Anurov M., Titkova S., Oettinger A.P., and Schumpelick V. Experimental evaluation of phospholipids and icodextrin in re-formation of peritoneal adhesions. Br J Surg 90 (2003) 1604-1607
104. Wallwiener D., Meyer A., and Bastert G. Adhesion formation of the parietal and visceral peritoneum: an explanation for the controversy on the use of autologous and alloplastic barriers?. Fertil Steril 69 (1998) 132-137
105. De Cherney A.H., and di Zerega G.S. Clinical problem of intraperitoneal postsurgical adhesion formation following general surgery and the use of adhesion prevention barriers. Surg Clin North Am 77 (1997) 671-688
106. Elkins T.E., Bury R.J., Ritter J.L., Ling F.W., Ahokas R.A., Homsey C.A., et al. Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat. Fertil Steril 41 (1984) 926-928
107. Fredericks C.M., Kotry I., Holtz G., Askalani A.H., and Serour G.I. Adhesion prevention in the rabbit with carboxymethylcellulose. Am J Obstet Gynecol 155 (1986) 667-670
108. Mediana M., Paddock H.N., Connelly R.J., and Schwaitzberg S.D. Novel antiadhesion barrier does not prevent anastomotic healing in a rabbit model. J Invest Surg 8 3 (1995) 179-186
109. Li T.C., and Cooke I.D. The value of an absorbable adhesion barrier, interceed, in the prevention of the adhesion reformation following microsurgical adhesiolysis. Br J Obstet Gynaecol 101 (1994) 335-339
110. Qeralt C.B., Laguens G., Lozano R., and Morandeira J.R. Prevention of peritonitis with oxidized regenerated celluloses. Infect Surg 12 (1987) 659-660
111. ® surgical membrane) is superior to oxidized regenerated cellulose (Interceed TC7+) in preventing adhesions. Fertil Steril 64 (1995) 668
112. Sawada T., Nishizawa H., Nishio E., and Kadowaki M. Postoperative adhesion prevention with an oxidized regenerated cellulose adhesion barrier in infertile woman. J Reprod Med 45 (2000) 387-389
113. Diamond M.P., Linsky C.B., Cunningham T., Constantine B., diZerega G.S., and DeCherney A.H. A model for sidewall adhesion in the rabbit; reduction by an absorbable barrier. Microsurgery 8 (1987) 197
114. Diamond M.P. Animal adhesion models: design, variables and relevance. Pelvic surgery (1997), Springer Verlag, Heidelberg, Germany p. 65-70.
115. Franklin R.R., and Ovarian study group. Reduction of ovarian adhesions by the use of Interceed. Obstet Gynecol 86 (1995) 335-340
116. Haney A.F. Removal of surgical barriers of expanded polytetrafluoroethylene at second-look laparoscopy was not associated with adhesion formation. Fertil Steril 68 (1997) 721-723
117. Schneider A., Bennek J., Olsen K.O., Weiss J., Schmidt W., and Rolle U. Experimental study evaluating the effect of a barrier method on postoperative intraabdominal adhesions. Digest Disea Sci 51 3 (2006) 566-570
118. Warn R., Harvey P., Warn A., Foley-Comer A., Heldin P., Versnel M., et al. HGF/SF induces mesothelial cell migration and proliferation by autocrine and paracrine pathways. Exp Cell Res 267 (2001) 258-266
119. Duan H.F., Wu C.T., Wu D.L., Lu Y., Liu H.J., Ha X.Q., et al. Treatment of myocardial ischemia with bone marrow derived mesenchymal stem cells overexpressing hepatocyte growth factor. Mol Ther 8 (2003) 467-474
120. Yang J., Dai C., and Liu Y. Systemic administration of naked plasmid encoding Hepatocyte growth factor ameliorates chronic renal fibrosis in mice. Gene Ther 8 (2001) 1470-1479
121. Liu H.J., Wu C.T., Duan H.F., Wu B., Lu Z.Z., and Wang L. Adenoviral-mediated gene expression of Hepatocyte growth factor prevents postoperative peritoneal adhesion in rat model. Surgery 140 3 (2006) 441-447