Mechanism and regulation of the two-component FMN-dependent monooxygenase ActVA-ActVB from Streptomyces coelicolor

Journal of Biological Chemistry

Volumn 283, Issue 16, 2008, Pages 10287-10296

  Valton, Julien ^a   Mathevon, Carole ^b,c,d   Fontecave, Marc ^b,c,d   Nivière, Vincent ^b,c,d   Ballou, David P ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b CEA GRENOBLE   (France)

^c CNRS   (France)

^d UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; CATALYSIS; HYDROXYLATION; PROTEINS; SPECTROPHOTOMETRY;

ANTIBIOTIC ACTINORHODIN; FLAVIN OXIDOREDUCTASE; FLAVIN-DEPENDENT MONOOXYGENASE; MONOOXYGENASE ACTIVITIES; MONOOXYGENASES; PROTEIN COMPLEXES; STOPPED-FLOW SPECTROPHOTOMETRY; STREPTOMYCES COELICOLOR;

REACTION INTERMEDIATES;

ACTVA ENZYME; ACTVB ENZYME; BACTERIAL ENZYME; DIHYDROKALAFUNGIN; FLAVINE MONONUCLEOTIDE REDUCTASE; HYDROPEROXIDE; KALAFUNGIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; MIXED FUNCTION OXIDASE; OXYGEN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SPECTROPHOTOMETRY; STREPTOMYCES COELICOLOR; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; KINETICS; METABOLISM; METHODOLOGY; PH; PROTEIN BINDING; TEMPERATURE; TIME;

STREPTOMYCES COELICOLOR;

BINDING SITES; FMN REDUCTASE; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN-ION CONCENTRATION; KINETICS; MIXED FUNCTION OXYGENASES; MODELS, BIOLOGICAL; MODELS, CHEMICAL; OXYGEN; PROTEIN BINDING; SPECTROPHOTOMETRY; STREPTOMYCES COELICOLOR; SUBSTRATE SPECIFICITY; TEMPERATURE; TIME FACTORS;

EID: 44849143455     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709730200     Document Type: Article

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