Mechanism and substrate specificity of the flavin reductase ActVB from Streptomyces coelicolor

Journal of Biological Chemistry

Volumn 278, Issue 1, 2003, Pages 296-303

  Filisetti, Laurent ^a   Fontecave, Marc ^a   Nivière, Vincent ^a  

^a CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; PROTEINS; REDUCTION;

SYNTHETIC FLAVINS;

BIOCHEMICAL ENGINEERING;

FLAVIN REDUCTASE; FLAVOPROTEIN; OXIDOREDUCTASE; PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; RIBITOL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ISOLATION PROCEDURE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; REDUCTION; STREPTOMYCES COELICOLOR;

BINDING SITES; FLAVIN MONONUCLEOTIDE; FLAVINS; FMN REDUCTASE; KINETICS; MOLECULAR STRUCTURE; NAD; NUCLEOTIDES; OXIDATION-REDUCTION; STREPTOMYCES; SUBSTRATE SPECIFICITY;

ACTINOBACTERIA (CLASS); STREPTOMYCES; STREPTOMYCES COELICOLOR; UNCULTURED ACTINOMYCETE;

EID: 0037414756     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209689200     Document Type: Article

References (30)

1. Fontecave, M., Covès, J., and Pierre, J. L. (1994) BioMetals 7, 3-8
2. Nivière, V., Vanoni, M. A., Zanetti, G., and Fontecave, M. (1998) Biochemistry 37, 11879-11887
3. Ingelman, M., Ramaswamy, S., Nivière, V., Fontecave, M., and Eklund, H. (1999) Biochemistry 38, 7040-7049
4. Covès, J., and Fontecave, M. (1993) Eur. J. Biochem. 211, 635-641
5. Zenno, S., Saigo, K., Kanoh, H., and Inouye, S. (1994) J. Bacteriol. 176, 3536-3543
6. Jeffers, C. E., and Tu, S.-C. (2001) Biochemistry, 40, 1749-1754
7. Kendrew, S. G., Harding, S. E., Hopwood, D. A., and Marsh, E. N. G. (1995) J. Biol. Chem. 270, 17339-17343
8. Thibaut, D., Ratet, N., Bish, D., Faucher, D., Debussche, L., and Blanche, F. (1995) J. Bacteriol. 177, 5199-5205
9. Parry, R. J., and Li, W. (1997) J. Biol. Chem. 272, 23303-23311
10. Galan, E. D., Prieto, M. A., and Garcia, J. L. (2000) J. Bacteriol. 182, 627-636
11. Gray, K. A., Pogrebinsky, O. S., Mrachko, G. T., Xi, L., Monticello, D. J., and Squires, C. H. (1996) Nat. Biotechnol. 14, 1705-1709
12. Uetz, T., Schneider, R., Snozzi, M., and Egli, T. (1992) J. Bacteriol. 174, 1179-1188
13. Witschel, M., Nagel, S., and Egli, T. (1997) J. Bacteriol. 179, 6937-6943
14. Fieschi, F., Nivière, V., Frier, C., Décout, J. L., and Fontecave, M. (1995) J. Biol. Chem. 270, 30392-30400
15. Eschenbrenner, M., Covès, J., and Fontecave, M. (1995) J. Biol. Chem. 270, 20550-20555
16. Nivière, V., Fieschi, F., Décout, J. L., and Fontecave, M. (1996) J. Biol. Chem. 271, 16656-16661
17. Nivière, V., Fieschi, F., Décout, J. L., and Fontecave, M. (1999) J. Biol. Chem. 274, 18252-18260
18. Fontecave, M., Eliasson, R., and Reichard, P. (1987) J. Biol. Chem. 262, 12325-12331
19. Zenno, S., and Saigo, K. (1994) J. Bacteriol. 176, 3544-3551
20. Bruns, C. M., and Karplus, P. A. (1995) J. Mol. Biol. 247, 125-145
21. Vadas, A., Monbouquette, H. G., Johnson, E., and Schröder, I. (1999) J. Biol. Chem. 274, 36715-36721
22. Chiu, H. J., Johnson, E., Schröder, I., and Rees, D. C. (2001) Structure 9, 311-319
23. Laemmli, U. K. (1970) Nature 227, 680-685
24. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
25. Segel, I. H. (1975) Enzyme Kinetics, John Wiley & Sons, Inc., New York
26. Massey, V., Matthews, R. G., Foust, G. P., Howell, L. G., Williams, C. H., Zanetti, G., and Ronchi, S. (1970) in Pyridine Nucleotide-Dependent Dehydrogenases (Sund, H., ed) pp. 393-409, Springer-Verlag, Berlin
27. Zanetti, G., and Aliverti, A. (1991) in Chemistry and Biochemistry of Flavoproteins, Vol. II (Muller, F., ed) pp. 306-312, CRC Press, Inc., Boca Raton, FL
28. Rudolph, F. B., and Fromm, H. J. (1979) Methods Enzymol. 63, 139-159
29. Dalziel, K. (1973) in The Enzymes, 3rd Ed. (Boyer, P. D., ed) Vol. XI, pp. 2-59, Academic Press, Inc., New York
30. Spector, T., and Cleland, W. W. (1981) Biochem. Pharmacol. 30, 1-7