메뉴 건너뛰기




Volumn 52, Issue 4, 2008, Pages 323-332

Loss of Sox9 function results in defective chondrocyte differentiation of mouse embryonic stem cells in vitro

Author keywords

Chondrogenesis; In vitro differentiation; Mesenchymal condensations; Sox9

Indexed keywords

TRANSCRIPTION FACTOR SOX5; TRANSCRIPTION FACTOR SOX8;

EID: 44849141765     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.072490gh     Document Type: Article
Times cited : (28)

References (44)
  • 1
    • 0041662164 scopus 로고    scopus 로고
    • SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes
    • AIGNER, T., GEBHARD, P.M., SCHMID, E., BAU, B., HARLEY, V. and POSCHL, E. (2003). SOX9 expression does not correlate with type II collagen expression in adult articular chondrocytes. Matrix Biol. 22: 363-372.
    • (2003) Matrix Biol , vol.22 , pp. 363-372
    • AIGNER, T.1    GEBHARD, P.M.2    SCHMID, E.3    BAU, B.4    HARLEY, V.5    POSCHL, E.6
  • 2
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • AKIYAMA, H., CHABOISSIER, M.C., MARTIN, J.F., SCHEDL, A. and DE CROMBRUGGHE, B. (2002). The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 16: 2813-2828.
    • (2002) Genes Dev , vol.16 , pp. 2813-2828
    • AKIYAMA, H.1    CHABOISSIER, M.C.2    MARTIN, J.F.3    SCHEDL, A.4    DE CROMBRUGGHE, B.5
  • 3
    • 0032476590 scopus 로고    scopus 로고
    • Serum response factor is essential for mesoderm formation during mouse embryogenesis
    • ARSENIAN, S., WEINHOLD, B., OELGESCHLAGER, M., RUTHER, U. and NORDHEIM, A. (1998). Serum response factor is essential for mesoderm formation during mouse embryogenesis. EMBO J. 17: 6289-6299.
    • (1998) EMBO J , vol.17 , pp. 6289-6299
    • ARSENIAN, S.1    WEINHOLD, B.2    OELGESCHLAGER, M.3    RUTHER, U.4    NORDHEIM, A.5
  • 7
    • 0034669139 scopus 로고    scopus 로고
    • Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators
    • BOWLES, J., SCHEPERS, G. and KOOPMAN, P. (2000). Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Dev. Biol. 227: 239-255.
    • (2000) Dev. Biol , vol.227 , pp. 239-255
    • BOWLES, J.1    SCHEPERS, G.2    KOOPMAN, P.3
  • 8
    • 0032511081 scopus 로고    scopus 로고
    • Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer
    • BRIDGEWATER, L.C., LEFEBVRE, V. and DE CROMBRUGGHE, B. (1998). Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer. J. Biol. Chem. 273: 14998-15006.
    • (1998) J. Biol. Chem , vol.273 , pp. 14998-15006
    • BRIDGEWATER, L.C.1    LEFEBVRE, V.2    DE CROMBRUGGHE, B.3
  • 9
    • 0032735947 scopus 로고    scopus 로고
    • Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis
    • BROWN, D., WAGNER, D., LI, X., RICHARDSON, J.A. and OLSON, E.N. (1999). Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. Development 126: 4317-4329.
    • (1999) Development , vol.126 , pp. 4317-4329
    • BROWN, D.1    WAGNER, D.2    LI, X.3    RICHARDSON, J.A.4    OLSON, E.N.5
  • 11
    • 0035574614 scopus 로고    scopus 로고
    • Regulatory mechanisms in the pathways of cartilage and bone formation
    • DE CROMBRUGGHE, B., LEFEBVRE, V. and NAKASHIMA, K. (2001). Regulatory mechanisms in the pathways of cartilage and bone formation. Curr. Opin. Cell Biol. 13: 721-727.
    • (2001) Curr. Opin. Cell Biol , vol.13 , pp. 721-727
    • DE CROMBRUGGHE, B.1    LEFEBVRE, V.2    NAKASHIMA, K.3
  • 12
    • 0033835868 scopus 로고    scopus 로고
    • Cellular interactions and signaling in cartilage development
    • DELISE, A.M., FISCHER, L. and TUAN, R.S. (2000). Cellular interactions and signaling in cartilage development. Osteoarthritis. Cartilage. 8: 309-334.
    • (2000) Osteoarthritis. Cartilage , vol.8 , pp. 309-334
    • DELISE, A.M.1    FISCHER, L.2    TUAN, R.S.3
  • 15
    • 0020615253 scopus 로고    scopus 로고
    • HOUSTON, C.S., OPITZ, J.M., SPRANGER, J.W., MACPHERSON, R.I., REED, M.H., GILBERT, E.F., HERRMANN, J. and SCHINZEL, A. (1983). The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux et al. in 1971. Am. J. Med. Genet. 15: 3-28.
    • HOUSTON, C.S., OPITZ, J.M., SPRANGER, J.W., MACPHERSON, R.I., REED, M.H., GILBERT, E.F., HERRMANN, J. and SCHINZEL, A. (1983). The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux et al. in 1971. Am. J. Med. Genet. 15: 3-28.
  • 16
    • 0035793055 scopus 로고    scopus 로고
    • The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones
    • HUANG, W., CHUNG, U.I., KRONENBERG, H.M. and DE CROMBRUGGHE, B. (2001). The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proc. Natl. Acad. Sci. USA 98: 160-165.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 160-165
    • HUANG, W.1    CHUNG, U.I.2    KRONENBERG, H.M.3    DE CROMBRUGGHE, B.4
  • 17
    • 0036195191 scopus 로고    scopus 로고
    • Conditional inactivation of Sox9: A mouse model for campomelic dysplasia
    • KIST, R., SCHREWE, H., BALLING, R. and SCHERER, G. (2002). Conditional inactivation of Sox9: a mouse model for campomelic dysplasia. Genesis. 32: 121-123.
    • (2002) Genesis , vol.32 , pp. 121-123
    • KIST, R.1    SCHREWE, H.2    BALLING, R.3    SCHERER, G.4
  • 18
    • 0034176844 scopus 로고    scopus 로고
    • Embryonic stem cell-derived chondrogenic differentiation in vitro: Activation by BMP-2 and BMP-4
    • KRAMER, J., HEGERT, C., GUAN, K., WOBUS, A.M., MÜLLER, P.K. and ROHWEDEL, J. (2000). Embryonic stem cell-derived chondrogenic differentiation in vitro: activation by BMP-2 and BMP-4. Mech. Dev. 92: 193-205.
    • (2000) Mech. Dev , vol.92 , pp. 193-205
    • KRAMER, J.1    HEGERT, C.2    GUAN, K.3    WOBUS, A.M.4    MÜLLER, P.K.5    ROHWEDEL, J.6
  • 20
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • KUHN, R., RAJEWSKY, K. and MÜLLER, W. (1991). Generation and analysis of interleukin-4 deficient mice. Science 254: 707-710.
    • (1991) Science , vol.254 , pp. 707-710
    • KUHN, R.1    RAJEWSKY, K.2    MÜLLER, W.3
  • 22
    • 0035093218 scopus 로고    scopus 로고
    • Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity
    • LEFEBVRE, L., DIONNE, N., KARASKOVA, J., SQUIRE, J.A. and NAGY, A. (2001). Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity. Nat. Genet. 27: 257-258.
    • (2001) Nat. Genet , vol.27 , pp. 257-258
    • LEFEBVRE, L.1    DIONNE, N.2    KARASKOVA, J.3    SQUIRE, J.A.4    NAGY, A.5
  • 23
    • 0030899814 scopus 로고    scopus 로고
    • SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
    • LEFEBVRE, V., HUANG, W., HARLEY, V.R., GOODFELLOW, P.N. and DE CROMBRUGGHE, B. (1997). SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol. Cell Biol. 17: 2336-2346.
    • (1997) Mol. Cell Biol , vol.17 , pp. 2336-2346
    • LEFEBVRE, V.1    HUANG, W.2    HARLEY, V.R.3    GOODFELLOW, P.N.4    DE CROMBRUGGHE, B.5
  • 24
    • 0032189223 scopus 로고    scopus 로고
    • A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene
    • LEFEBVRE, V., LI, P. and DE CROMBRUGGHE, B. (1998). A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J. 17: 5718-5733.
    • (1998) EMBO J , vol.17 , pp. 5718-5733
    • LEFEBVRE, V.1    LI, P.2    DE CROMBRUGGHE, B.3
  • 25
    • 8944238474 scopus 로고    scopus 로고
    • An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes
    • LEFEBVRE, V., ZHOU, G., MUKHOPADHYAY, K., SMITH, C.N., ZHANG, Z., EBERSPAECHER, H., ZHOU, X., SINHA, S., MAITY, S.N. and DE CROMBRUGGHE, B. (1996). An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Mol. Cell Biol. 16: 4512-4523.
    • (1996) Mol. Cell Biol , vol.16 , pp. 4512-4523
    • LEFEBVRE, V.1    ZHOU, G.2    MUKHOPADHYAY, K.3    SMITH, C.N.4    ZHANG, Z.5    EBERSPAECHER, H.6    ZHOU, X.7    SINHA, S.8    MAITY, S.N.9    DE CROMBRUGGHE, B.10
  • 26
    • 0029033699 scopus 로고
    • A clinical and genetic study of campomelic dysplasia
    • MANSOUR, S., HALL, C.M., PEMBREY, M.E. and YOUNG, I.D. (1995). A clinical and genetic study of campomelic dysplasia. J. Med. Genet. 32: 415-420.
    • (1995) J. Med. Genet , vol.32 , pp. 415-420
    • MANSOUR, S.1    HALL, C.M.2    PEMBREY, M.E.3    YOUNG, I.D.4
  • 27
    • 0002701075 scopus 로고    scopus 로고
    • Production of Targeted Embryonic Stem Cell Clones
    • JOYNER, A. L, ed, Oxford University Press, Oxford, pp
    • MATISE, M. P., AUERBACH, W., and JOYNER, A. L. 2000. Production of Targeted Embryonic Stem Cell Clones. In Gene Targeting: A Practical Approach(JOYNER, A. L., ed.). Oxford University Press, Oxford, pp.101-132.
    • (2000) Gene Targeting: A Practical Approach , pp. 101-132
    • MATISE, M.P.1    AUERBACH, W.2    JOYNER, A.L.3
  • 28
    • 0025949448 scopus 로고
    • Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing
    • METSÄRANTA, M., TOMAN, D., DE CROMBRUGGHE, B. and VUORIO, E. (1991). Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. J. Biol. Chem. 266: 16862-16869.
    • (1991) J. Biol. Chem , vol.266 , pp. 16862-16869
    • METSÄRANTA, M.1    TOMAN, D.2    DE CROMBRUGGHE, B.3    VUORIO, E.4
  • 29
    • 0036384136 scopus 로고    scopus 로고
    • Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2
    • MOFTAH, M.Z., DOWNIE, S.A., BRONSTEIN, N.B., MEZENTSEVA, N., PU, J., MAHER, P.A. and NEWMAN, S.A. (2002). Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2. Dev. Biol. 249: 270-282.
    • (2002) Dev. Biol , vol.249 , pp. 270-282
    • MOFTAH, M.Z.1    DOWNIE, S.A.2    BRONSTEIN, N.B.3    MEZENTSEVA, N.4    PU, J.5    MAHER, P.A.6    NEWMAN, S.A.7
  • 32
    • 0028107165 scopus 로고
    • Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis
    • OBERLENDER, S.A. and TUAN, R.S. (1994). Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 120: 177-187.
    • (1994) Development , vol.120 , pp. 177-187
    • OBERLENDER, S.A.1    TUAN, R.S.2
  • 33
    • 13944260928 scopus 로고    scopus 로고
    • Normal lung development and function after Sox9 inactivation in the respiratory epithelium
    • PERL, A.K., KIST, R., SHAN, Z., SCHERER, G. and WHITSETT, J.A. (2005). Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis. 41: 23-32.
    • (2005) Genesis , vol.41 , pp. 23-32
    • PERL, A.K.1    KIST, R.2    SHAN, Z.3    SCHERER, G.4    WHITSETT, J.A.5
  • 34
    • 0034646703 scopus 로고    scopus 로고
    • SOX9 enhances aggrecan gene promoter/enhancer activity and is up- regulated by retinoic acid in a cartilage-derived cell line, TC6
    • SEKIYA, I., TSUJI, K., KOOPMAN, P., WATANABE, H., YAMADA, Y., SHINOMIYA, K., NIFUJI, A. and NODA, M. (2000). SOX9 enhances aggrecan gene promoter/enhancer activity and is up- regulated by retinoic acid in a cartilage-derived cell line, TC6. J. Biol. Chem. 275: 10738-10744.
    • (2000) J. Biol. Chem , vol.275 , pp. 10738-10744
    • SEKIYA, I.1    TSUJI, K.2    KOOPMAN, P.3    WATANABE, H.4    YAMADA, Y.5    SHINOMIYA, K.6    NIFUJI, A.7    NODA, M.8
  • 35
    • 0029977067 scopus 로고    scopus 로고
    • Sex reversal by loss of the C-terminal transactivation domain of human SOX9
    • SÜDBECK, P., SCHMITZ, M.L., BAEUERLE, P.A. and SCHERER, G. (1996). Sex reversal by loss of the C-terminal transactivation domain of human SOX9. Nat. Genet. 13: 230-232.
    • (1996) Nat. Genet , vol.13 , pp. 230-232
    • SÜDBECK, P.1    SCHMITZ, M.L.2    BAEUERLE, P.A.3    SCHERER, G.4
  • 36
    • 0032518164 scopus 로고    scopus 로고
    • Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: A transient gene-integration marker for ES cells
    • TANIGUCHI, M., SANBO, M., WATANABE, S., NARUSE, I., MISHINA, M. and YAGI, T. (1998). Efficient production of Cre-mediated site-directed recombinants through the utilization of the puromycin resistance gene, pac: a transient gene-integration marker for ES cells. Nucleic Acids Res. 26: 679-680.
    • (1998) Nucleic Acids Res , vol.26 , pp. 679-680
    • TANIGUCHI, M.1    SANBO, M.2    WATANABE, S.3    NARUSE, I.4    MISHINA, M.5    YAGI, T.6
  • 38
    • 0033559518 scopus 로고    scopus 로고
    • From head to toes: The multiple facets of Sox proteins
    • WEGNER, M. (1999). From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res. 27: 1409-1420.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1409-1420
    • WEGNER, M.1
  • 42
    • 0022553946 scopus 로고
    • Epithelial effects on limb chondrogenesis involve extracellular matrix and cell shape
    • ZANETTI, N.C. and SOLURSH, M. (1986). Epithelial effects on limb chondrogenesis involve extracellular matrix and cell shape. Dev. Biol. 113: 110-118.
    • (1986) Dev. Biol , vol.113 , pp. 110-118
    • ZANETTI, N.C.1    SOLURSH, M.2
  • 43
    • 0030855005 scopus 로고    scopus 로고
    • Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis
    • ZHAO, Q., EBERSPAECHER, H., LEFEBVRE, V. and DE CROMBRUGGHE, B. (1997). Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Dev. Dyn. 209: 377-386.
    • (1997) Dev. Dyn , vol.209 , pp. 377-386
    • ZHAO, Q.1    EBERSPAECHER, H.2    LEFEBVRE, V.3    DE CROMBRUGGHE, B.4
  • 44
    • 0032511091 scopus 로고    scopus 로고
    • Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo
    • ZHOU, G., LEFEBVRE, V., ZHANG, Z., EBERSPAECHER, H. and DE CROMBRUGGHE, B. (1998). Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo. J. Biol. Chem. 273: 14989-14997.
    • (1998) J. Biol. Chem , vol.273 , pp. 14989-14997
    • ZHOU, G.1    LEFEBVRE, V.2    ZHANG, Z.3    EBERSPAECHER, H.4    DE CROMBRUGGHE, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.