Preservation of a critical epitope core region is associated with the high degree of flaviviral cross-reactivity exhibited by a dengue-specific CD4+ T cell clone

European Journal of Immunology

Volumn 38, Issue 4, 2008, Pages 1050-1057

  Moran, Edward ^a,d   Simmons, Cameron ^b   Chau, Nguyen Vinh ^c   Luhn, Kerstin ^a   Wills, Bridget ^b,b   Dung, Nguyen Phuong ^b   Thao, Le Thi Thu ^c   Hien, Tran Tinh ^c,c   Farrar, Jeremy ^b   Rowland Jones, Sarah ^a   Dong, Tao ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Dengue; Epitope; T cell

Indexed keywords

GAMMA INTERFERON; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NONSTRUCTURAL PROTEIN 3; T LYMPHOCYTE RECEPTOR; EPITOPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVITY; CELL CLONE; CONTROLLED STUDY; CROSS REACTION; CYTOKINE PRODUCTION; DENGUE; FLAVIVIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; PRIORITY JOURNAL; CELL CULTURE; CELL SEPARATION; CHEMISTRY; IMMUNOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; CELLS, CULTURED; CROSS REACTIONS; EPITOPES, T-LYMPHOCYTE; FLAVIVIRUS; HUMANS; MOLECULAR SEQUENCE DATA;

EID: 44849139919     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737699     Document Type: Article

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