Identification of amino acids involved in recognition by dengue virus NS3-specific, HLA-DR15-restricted cytotoxic CD4+ T-cell clones

Journal of Virology

Volumn 70, Issue 5, 1996, Pages 3108-3117

  Zeng, Lingling ^a   Kurane, Ichiro ^b   Okamoto, Yuji ^b   Ennis, Francis A ^b   Brinton, Margo A ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID METABOLISM; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; DENGUE VIRUS; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; SEROTYPE; VIRUS EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CERCOPITHECUS AETHIOPS; CLONE CELLS; CROSS REACTIONS; CYTOTOXICITY, IMMUNOLOGIC; DENGUE; DENGUE VIRUS; EPITOPES; HISTOCOMPATIBILITY TESTING; HLA-DR ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RNA HELICASES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SEROTYPING; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRAL VACCINES;

EID: 0029879040     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.5.3108-3117.1996     Document Type: Article

References (39)

1. Anderson, D. C., W. C. A. van Schooten, A. Janson, M. E. Barry, and R. R. P. de Vires. 1990. Molecular mapping of interactions between a Mycobactertum leprae-specific T cell epitope. the restricting HLA-DR2 molecule and two specific T cell receptors. J. Immunol. 144:2459-2464.
2. Blackwell, J. L., and M. A. Brinton. Unpublished data.
3. Bodmer, J. G., S. G. E. Marsh, E. D. Albert, W. F. Bodmer, B. Dupont, H. A. Erlich, B. Mach, W. R. Mayr, P. Parham, T. Sasazuki, G. M. T. Schreuder, J. L. Strominger, A. Svejgaard, and P. I. Terasaki. 1994. Nomenclature for factors of the HLA system, 1994. Hum. Immunol. 41:1-20.
4. + human cytotoxic T lymphocytes. J. Virol. 63:5086-5091.
5. Cahour, A., B. Falgout, and C.-J. Lai. 1992. Cleavage of the dengue virus polyprotein at the NS3VNS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3. whereas NS4A/NS4B may be processed by a cellular protease. J. Virol. 66:1535-1542.
6. Celis, E., and R. W. Karr. 1989. Presentation of an immunodominant T-cell epitope of hepatitis B surface antigen by the HLA-DPw4 molecule J Virol. 63:747-752.
7. Chambers, T. J., C. S. Hahn, R. Galler, and C. M. Rice. 1990. Flavivirus genome organization, expression, and replication, Annu. Rev. Microbiol. 44:649-688.
8. Chicz, R. M., R. G. Urban, J. C. Gorga, D. A. Vignali, W. S. Lane, and J. L. Strominger. 1993. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 178:27-47.
9. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
10. Fu, J., B. Tan, E. Yap, Y. Chan, and Y. Tan. 1992. Full-length cDNA sequence of dengue type 1 virus (Singapore strain S275/90). Virology 188:953-958.
11. Halstead, S. B. 1980. Immunological parameters of togavirus disease syndromes, p. 107-173 In R. W. Schlesinger (ed.). The toga-viruses: biology, structure, replication. Academic Press, Inc., New York.
12. Halstead, S. B. 1988. Pathogenesis of dengue: challenges to molecular biology. Science 239:476-481.
13. Halstead, S. B. 1989. Antibody, macrophages, dengue virus infection, shock, and hemorrhage, a pathogenic cascade. Rev. Infect. Dis. 11:3830-5834
14. Halstead, S. B. 1990. Global epidemiology of dengue hemorrhagic fever. Asian J. Trop. Med. Pub Health 21:636-641.
15. Hammond, S. A., E. Obah, P. Stanhope, C. R. Monell, M. Strand, F. M. Robbins, W. B. Bias, R. W. Karr, S. Koenig, and R. F. Siliciano. 1991. Characterization of a conserved T cell epitope in HIV-1 gp41 recognized by vaccine-induced human cytolytic T cells. J. Immunol. 146:1470-1477.
16. Harris, P. E., A. Maffei, Z. Liu, I. Colovai, E. F. Reed, G. Inghirami, and N. Suciu-Foca. 1993 Naturally processed cytokine-derived peptide bound to HLA-class II molecules J. Immunol. 151:5975-5983.
17. d. Science 256:1817-1820.
18. Irie, K., P. Mohan, Y. Sasaguri, R. Putnak, and R. Padmanabhan. 1989. Sequence analysis of cloned dengue virus type 2 genome (New Guinea-C strain) Gene 75:197-211.
19. + cytotoxic T-cell clones multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clones J. Virol. 65:1823-1828.
20. +, cytotoxic T-cell clone J Virol. 67:6285-6288.
21. Kurane, I., and F. A. Ennis. Unpublished data.
22. Kurane, I., and F. A. Ennis. 1992. Immunity and immunopathology in dengue virus infections. Semin. Immunol. 4:121-127.
23. Kurane, I., B. L. Innis, S. Nimmannitya, A. Nisalak, A. Meager, J. Janus, and F. A. Ennis. 1991. Activation of T lymphocytes in dengue virus intections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2 and interferon-gamma in children with dengue. J Clin. Invest. 88:1473-1480
24. Kurane, I., B. L. Innis, A. Nisalak, C. Hoke, S. Nimmannitya, A. Meager, and F. A. Ennis. 1989. Human responses to dengue virus antigens. Proliferaitive responses and interferon gamma production. J. Clin. Invest. 83:506-513
25. Kurane, I., A. Meager, and F. A. Ennis. 1989. Dengue virus-specific human T cell clones. Serotype cross-reactive proliferation, interferon γ production, and cytotoxic activity. J. Exp. Med. 170:763-775.
26. + cytotoxic T lymphocyte clones. J. Gen Virol. 76:2243-2249.
27. Livingston, P. G., I. Kurane, L.-C. Dai, Y. Okamoto, C.-J. Lai, R. Men, S. Karaki, M. Takiguchi, and F. A. Ennis. 1995. Dengue virus-specific, HLA-B35-resiricted, human CD+ cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities. J. Immunol 154:1287-1295.
28. Mackett, M., G. L. Smith, and B. Moss. 1984. General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes. J. Virol. 49:857-864
29. Mackow, E., Y. Makino, B. Zhao, Y. Zhang, L. Markoff, A. Buckler-White, M. Guiler, R. Chanock, and C.-J. Lai. 1987. The nucleotide sequence of dengue type 4 virus, analysis of genes coding for nonstructural proteins. Virology 159:217-228
30. Monath, T. P. 1994. Dengue, the risk to developed and developing countries Proc. Natl. Acad. Sci. USA 91:2395-2400
31. Osatomi, K., and H. Sumiyoshi. 1990. Complete nucleotide sequence of dengue type 3 virus genome RNA. Virology 176:643-647
32. Rico-Hesse, R. 1990. Molecular evolution and distribution of dengue virus type 1 and 2 in nature. Virology 174:479-493.
33. Rothman, A. L., I. Kurane, Y. M. Zhang, C.-J. Lai, and F. A. Ennis. 1989. Dengue virus-specific murine T-lymphocyte proliferation, serotype specificity and response to recombinant viral proteins. J. Virol. 63:2486-2491.
34. Rudensky, A. Y., S. Rath, P. Preston-Hurlburt, D. B. Murphy, and C. A. Janeway. 1991. On the complexity of self. Nature (London) 353:660-662.
35. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci USA 74:5463-5467.
36. Trent, D. W., J. A. Grant, L. Rosen, and T. P. Monath. 1983. Genetic variation among dengue 2 viruses of different geographic origin. Virology 128:271-284.
37. Tussey, L. G., M. Matsui, S. Rowland-Jones, R. Warburton, J. A. Frelinger, and A. McMichael. 1994. Analysis of mutant HLA-A2 molecules. Differential effects on peptide binding and CTL recognition. J. Immunol. 152:1213-1221.
38. Whitton, J. L., A. Tishon, H. Lewicki, J. Gebhard, T. Cook, M. Salvato, E. Joly, and M. B. A. Oldstone. 1989. Molecular analysis of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity. J. Virol. 63:4303-4310.
39. + human cytotoxic T lymphocyte clones of heterogeneous serotype specificities. J. Exp. Med. 182:853-863