메뉴 건너뛰기




Volumn 45, Issue 4, 2008, Pages 333-342

mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells

Author keywords

Adhesion molecules; Calcineurin inhibitors; E selectin; ICAM 1; mTOR inhibitors; VCAM 1

Indexed keywords

CALCINEURIN INHIBITOR; CASPASE 3; CASPASE 7; CELL ADHESION MOLECULE; CYCLOSPORIN A; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; RAPAMYCIN; TACROLIMUS; TUMOR NECROSIS FACTOR;

EID: 44849104570     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000119199     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0030823697 scopus 로고    scopus 로고
    • Cardiac allograft vasculopathy: A review
    • Weis M, von Scheidt W: Cardiac allograft vasculopathy: a review. Circulation 1997;96:2069-2077.
    • (1997) Circulation , vol.96 , pp. 2069-2077
    • Weis, M.1    von Scheidt, W.2
  • 2
    • 0142154057 scopus 로고    scopus 로고
    • Value of circulating adhesion molecules in assessing cardiac allograft vasculopathy
    • Wu YW, Lee CM, Lee YT, Wang SS, Huang PJ: Value of circulating adhesion molecules in assessing cardiac allograft vasculopathy. J Heart Lung Transplant 2003;22:1284-1287.
    • (2003) J Heart Lung Transplant , vol.22 , pp. 1284-1287
    • Wu, Y.W.1    Lee, C.M.2    Lee, Y.T.3    Wang, S.S.4    Huang, P.J.5
  • 3
    • 0035659395 scopus 로고    scopus 로고
    • Nephrotoxicity of immunosuppressive drugs: New insight and preventive strategies
    • Olyaei AJ, de Mattos AM, Bennett WM: Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. Curr Opin Crit Care 2001;7:384-389.
    • (2001) Curr Opin Crit Care , vol.7 , pp. 384-389
    • Olyaei, A.J.1    de Mattos, A.M.2    Bennett, W.M.3
  • 5
    • 0034654015 scopus 로고    scopus 로고
    • Association of glucocorticoids and cyclosporin A or rapamycin prevents Eselectin and IL-8 expression during LPSand TNF-mediated endothelial cell activation
    • Charreau B, Coupel S, Goret F, Pourcel C, Soulillou JP: Association of glucocorticoids and cyclosporin A or rapamycin prevents Eselectin and IL-8 expression during LPSand TNF-mediated endothelial cell activation. Transplantation 2000;69:945-953.
    • (2000) Transplantation , vol.69 , pp. 945-953
    • Charreau, B.1    Coupel, S.2    Goret, F.3    Pourcel, C.4    Soulillou, J.P.5
  • 6
    • 11144301278 scopus 로고    scopus 로고
    • The impact of immunosuppression on endothelial function
    • Trapp A, Weis M: The impact of immunosuppression on endothelial function. J Cardiovasc Pharmacol 2005;45:81-87.
    • (2005) J Cardiovasc Pharmacol , vol.45 , pp. 81-87
    • Trapp, A.1    Weis, M.2
  • 8
    • 25144476013 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of the endothelium
    • Aird WC: Spatial and temporal dynamics of the endothelium. J Thromb Haemost 2005;3:1392-1406.
    • (2005) J Thromb Haemost , vol.3 , pp. 1392-1406
    • Aird, W.C.1
  • 10
    • 0141799707 scopus 로고    scopus 로고
    • Expression of adhesion molecules and cytokines in vitro by endothelial cells seeded on various polymer surfaces coated with titaniumcarboxonitride
    • Lehle K, Buttstaedt J, Birnbaum DE: Expression of adhesion molecules and cytokines in vitro by endothelial cells seeded on various polymer surfaces coated with titaniumcarboxonitride. J Biomed Mater Res 2003;65:393-401.
    • (2003) J Biomed Mater Res , vol.65 , pp. 393-401
    • Lehle, K.1    Buttstaedt, J.2    Birnbaum, D.E.3
  • 11
    • 0028358367 scopus 로고
    • Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function
    • De Clerck LS, Bridts CH, Mertens AM, Moens MM, Stevens WJ: Use of fluorescent dyes in the determination of adherence of human leucocytes to endothelial cells and the effect of fluorochromes on cellular function. J Immunol Methods 1994;172:115-124.
    • (1994) J Immunol Methods , vol.172 , pp. 115-124
    • De Clerck, L.S.1    Bridts, C.H.2    Mertens, A.M.3    Moens, M.M.4    Stevens, W.J.5
  • 14
    • 0030756152 scopus 로고    scopus 로고
    • Different inhibitory effects of immunosuppressive drugs on human and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor
    • Mohacsi PJ, Tuller D, Hulliger B, Wijngaard PL: Different inhibitory effects of immunosuppressive drugs on human and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor. J Heart Lung Transplant 1997;16:484-492.
    • (1997) J Heart Lung Transplant , vol.16 , pp. 484-492
    • Mohacsi, P.J.1    Tuller, D.2    Hulliger, B.3    Wijngaard, P.L.4
  • 15
    • 0033064431 scopus 로고    scopus 로고
    • Effect of cyclosporin A or tacrolimus on the function of blood-brain barrier cells
    • Kochi S, Takanaga H, Matsuo H, Naito M, Tsuruo T, Sawada Y: Effect of cyclosporin A or tacrolimus on the function of blood-brain barrier cells. Eur J Pharmacol 1999;372:287-295.
    • (1999) Eur J Pharmacol , vol.372 , pp. 287-295
    • Kochi, S.1    Takanaga, H.2    Matsuo, H.3    Naito, M.4    Tsuruo, T.5    Sawada, Y.6
  • 16
    • 0032210023 scopus 로고    scopus 로고
    • Cyclosporine, but not FK 506 and rapamycin, enhances cell proliferation in mouse medullary thick ascending cultured cells
    • Wu MS, Yu HM, Hong JJ, Lai BC, Huang CC, Vandewalle A: Cyclosporine, but not FK 506 and rapamycin, enhances cell proliferation in mouse medullary thick ascending cultured cells. Transplant Proc 1998;30:3565-3566.
    • (1998) Transplant Proc , vol.30 , pp. 3565-3566
    • Wu, M.S.1    Yu, H.M.2    Hong, J.J.3    Lai, B.C.4    Huang, C.C.5    Vandewalle, A.6
  • 17
    • 33646242034 scopus 로고    scopus 로고
    • Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines
    • Garweg JG, Wegmann-Burns M, Goldblum D: Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines. Graefes Arch Clin Exp Ophthalmol 2006;244:382-389.
    • (2006) Graefes Arch Clin Exp Ophthalmol , vol.244 , pp. 382-389
    • Garweg, J.G.1    Wegmann-Burns, M.2    Goldblum, D.3
  • 18
    • 11144313725 scopus 로고    scopus 로고
    • In vitro effect of cyclosporin A, mitomycin C and prednisolone on cell kinetics in cultured human umbilical vein endothelial cells
    • Seki Y, Toba K, Fuse I, Sato N, Niwano H, Takahashi H, Tanabe N, Aizawa Y: In vitro effect of cyclosporin A, mitomycin C and prednisolone on cell kinetics in cultured human umbilical vein endothelial cells. Thromb Res 2005;115:219-228.
    • (2005) Thromb Res , vol.115 , pp. 219-228
    • Seki, Y.1    Toba, K.2    Fuse, I.3    Sato, N.4    Niwano, H.5    Takahashi, H.6    Tanabe, N.7    Aizawa, Y.8
  • 19
    • 0036136821 scopus 로고    scopus 로고
    • In vitro effects of cyclosporin A on the expression of adhesion molecules on human umbilical vein endothelial cells
    • Markovic S, Raab M, Daxecker H, Griesmacher A, Karimi A, Müller MM: In vitro effects of cyclosporin A on the expression of adhesion molecules on human umbilical vein endothelial cells. Clin Chim Acta 2002;316:25-31.
    • (2002) Clin Chim Acta , vol.316 , pp. 25-31
    • Markovic, S.1    Raab, M.2    Daxecker, H.3    Griesmacher, A.4    Karimi, A.5    Müller, M.M.6
  • 20
    • 0032244550 scopus 로고    scopus 로고
    • Cyclosporin A decreases lymphocyte migration to the heart allograft through suppression of their L-selectin expression
    • Maksymowicz M, Lukomska B, Ziolkowska A, Janczewska S, Cybulska E, Olszewski WL: Cyclosporin A decreases lymphocyte migration to the heart allograft through suppression of their L-selectin expression. Ann Transplant 1998;3:34-36.
    • (1998) Ann Transplant , vol.3 , pp. 34-36
    • Maksymowicz, M.1    Lukomska, B.2    Ziolkowska, A.3    Janczewska, S.4    Cybulska, E.5    Olszewski, W.L.6
  • 21
    • 18544389096 scopus 로고    scopus 로고
    • Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS: Paradoxical proinflammatory effect on the microvascular endothelium
    • Rafiee P, Johnson CP, Li MS, Ogawa H, Heidemann J, Fisher PJ, Lamirand TH, Otterson MF, Wilson KT, Binion DG: Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS: paradoxical proinflammatory effect on the microvascular endothelium. J Biol Chem 2002;277:35605-35615.
    • (2002) J Biol Chem , vol.277 , pp. 35605-35615
    • Rafiee, P.1    Johnson, C.P.2    Li, M.S.3    Ogawa, H.4    Heidemann, J.5    Fisher, P.J.6    Lamirand, T.H.7    Otterson, M.F.8    Wilson, K.T.9    Binion, D.G.10
  • 22
    • 0343052748 scopus 로고    scopus 로고
    • FK506 suppresses the mitogen-induced increase in lymphocyte adhesiveness to endothelial cells, but does not affect endothelial cell activation in response to inflammatory stimuli
    • Karlsson H, Nassberger L: FK506 suppresses the mitogen-induced increase in lymphocyte adhesiveness to endothelial cells, but does not affect endothelial cell activation in response to inflammatory stimuli. Transplantation 1997;64:1217-1220.
    • (1997) Transplantation , vol.64 , pp. 1217-1220
    • Karlsson, H.1    Nassberger, L.2
  • 24
    • 34247340098 scopus 로고    scopus 로고
    • mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells
    • Schreml S, Lehle K, Birnbaum DE, Preuner JG: mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells. Int Immunopharmacol 2007;7:781-791.
    • (2007) Int Immunopharmacol , vol.7 , pp. 781-791
    • Schreml, S.1    Lehle, K.2    Birnbaum, D.E.3    Preuner, J.G.4
  • 25
    • 1642266620 scopus 로고    scopus 로고
    • Cardiac allograft vasculopathy: Advances in understanding its pathophysiology, prevention, and treatment
    • Pinney SP, Mancini D: Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment. Curr Opin Cardiol 2004;19:170-176.
    • (2004) Curr Opin Cardiol , vol.19 , pp. 170-176
    • Pinney, S.P.1    Mancini, D.2
  • 26
    • 0141544969 scopus 로고    scopus 로고
    • Cardiac allograft vasculopathy: Central role of endothelial injury leading to transplant 'atheroma'
    • Valantine HA: Cardiac allograft vasculopathy: central role of endothelial injury leading to transplant 'atheroma'. Transplantation 2003;76:891-899.
    • (2003) Transplantation , vol.76 , pp. 891-899
    • Valantine, H.A.1
  • 27
    • 16244377483 scopus 로고    scopus 로고
    • Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place
    • Lehle K, Birnbaum DE, Preuner JG: Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place. Transplant Proc 2005;37:159-161.
    • (2005) Transplant Proc , vol.37 , pp. 159-161
    • Lehle, K.1    Birnbaum, D.E.2    Preuner, J.G.3
  • 28
    • 3042572347 scopus 로고    scopus 로고
    • Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells
    • Riesterer O, Zingg D, Hummerjohann J, Bodis S, Pruschy M: Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells. Oncogene 2004;23:4624-4635.
    • (2004) Oncogene , vol.23 , pp. 4624-4635
    • Riesterer, O.1    Zingg, D.2    Hummerjohann, J.3    Bodis, S.4    Pruschy, M.5
  • 29
    • 13544249982 scopus 로고    scopus 로고
    • Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors
    • Sugatani T, Hruska KA: Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors. J Biol Chem 2005;280:3583-3589.
    • (2005) J Biol Chem , vol.280 , pp. 3583-3589
    • Sugatani, T.1    Hruska, K.A.2
  • 31
    • 0033984273 scopus 로고    scopus 로고
    • Acute and chronic tissue response to coronary stent implantation: Pathologic findings in human specimen
    • Grewe PH, Deneke T, Machraoui A, Barmeyer J, Muller KM: Acute and chronic tissue response to coronary stent implantation: pathologic findings in human specimen. J Am Coll Cardiol 2000;35:157-163.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 157-163
    • Grewe, P.H.1    Deneke, T.2    Machraoui, A.3    Barmeyer, J.4    Muller, K.M.5
  • 32
    • 26444533216 scopus 로고    scopus 로고
    • Persistently increased systemic, but not cardiac-specific, adhesion molecule expression and coronary endothelial dysfunction in human cardiac allografts
    • Wildhirt SM, Schulze C, Conrad N, Bauernschmitt R, Lange R, von Scheidt W: Persistently increased systemic, but not cardiac-specific, adhesion molecule expression and coronary endothelial dysfunction in human cardiac allografts. J Thorac Cardiovasc Surg 2005;130:1175.
    • (2005) J Thorac Cardiovasc Surg , vol.130 , pp. 1175
    • Wildhirt, S.M.1    Schulze, C.2    Conrad, N.3    Bauernschmitt, R.4    Lange, R.5    von Scheidt, W.6
  • 33
    • 0028841260 scopus 로고
    • Rapamycin inhibits transplant vasculopathy in long-surviving rat heart allografts
    • Schmid C, Heemann U, Azuma H, Tilney NL: Rapamycin inhibits transplant vasculopathy in long-surviving rat heart allografts. Transplantation 1995;60:729-733.
    • (1995) Transplantation , vol.60 , pp. 729-733
    • Schmid, C.1    Heemann, U.2    Azuma, H.3    Tilney, N.L.4
  • 34
    • 29544452676 scopus 로고    scopus 로고
    • Calcineurin-inhibitor-sparing immunosuppressive protocols
    • Bestard O, Cruzado JM, Grinyo JM: Calcineurin-inhibitor-sparing immunosuppressive protocols. Transplant Proc 2005;37:3729-3732.
    • (2005) Transplant Proc , vol.37 , pp. 3729-3732
    • Bestard, O.1    Cruzado, J.M.2    Grinyo, J.M.3
  • 35
    • 16444362802 scopus 로고    scopus 로고
    • Combating chronic renal allograft dysfunction: Optimal immunosuppressive regimens
    • Merville P: Combating chronic renal allograft dysfunction: optimal immunosuppressive regimens. Drugs 2005;65:615-631.
    • (2005) Drugs , vol.65 , pp. 615-631
    • Merville, P.1
  • 36
    • 0030917425 scopus 로고    scopus 로고
    • Selective expression of adhesion molecules on human brain microvascular endothelial cells
    • Stins MF, Gilles F, Kim KS: Selective expression of adhesion molecules on human brain microvascular endothelial cells. J Neuroimmunol 1997;76:81-90.
    • (1997) J Neuroimmunol , vol.76 , pp. 81-90
    • Stins, M.F.1    Gilles, F.2    Kim, K.S.3
  • 37
    • 0035998992 scopus 로고    scopus 로고
    • Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression
    • Haubitz M, Brunkhorst M: Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression. Transplant Proc 2002;34:1124-1126.
    • (2002) Transplant Proc , vol.34 , pp. 1124-1126
    • Haubitz, M.1    Brunkhorst, M.2
  • 38
    • 33745870161 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin modulates expression of adhesion molecules in endothelial cells
    • Wood SC, Bushar G, Tesfamariam B: Inhibition of mammalian target of rapamycin modulates expression of adhesion molecules in endothelial cells. Toxicol Lett 2006;165:242-249.
    • (2006) Toxicol Lett , vol.165 , pp. 242-249
    • Wood, S.C.1    Bushar, G.2    Tesfamariam, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.