In vitro effect of cyclosporin A, mitomycin C and prednisolone on cell kinetics in cultured human umbilical vein endothelial cells

Thrombosis Research

Volumn 115, Issue 3, 2005, Pages 219-228

  Seki, Yoshinobu ^a   Toba, Ken ^a   Fuse, Ichiro ^a   Sato, Naoaki ^a   Niwano, Hiroe ^b   Takahashi, Hoyu ^c   Tanabe, Naohito ^d   Aizawa, Yoshifusa ^a  

^a NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Niigata Prefectural Kamo Hospital   (Japan)

^d NIIGATA UNIVERSITY   (Japan)

Author keywords

Cell cycle; Cyclosporin A; Endothelial cell damage; Human umbilical vein endothelial cells; Mitomycin C; Prednisolone

Indexed keywords

CYCLOSPORIN A; MITOMYCIN C; PREDNISOLONE; RETINOBLASTOMA PROTEIN; THROMBOMODULIN;

ARTICLE; CELL ACTIVITY; CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DAMAGE; CELL KINETICS; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG ANTAGONISM; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYBRID CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SUPERNATANT; UMBILICAL VEIN;

BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FLOW CYTOMETRY; HUMANS; KINETICS; MITOMYCIN; NUCLEIC ACID SYNTHESIS INHIBITORS; PREDNISOLONE; UMBILICAL VEINS;

EID: 11144313725     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2004.09.001     Document Type: Article

References (47)

1. B.D. Kahan Cyclosporine N. Engl. J. Med. 321 1989 1725 1738
2. P. Kalhs, S. Brugger, I. Schwarzinger, H.T. Greinix, F. Keil, and P.A. Kyrle Microangiopathy following allogenic marrow transplantation Transplantation 60 1995 949 957
3. E. Holler, H.J. Kolb, E. Hiller, W. Mraz, W. Lehmacher, and B. Gleixner Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation Blood 73 1989 2018 2024
4. Z.R. Zeigler, R.K. Shadduck, J. Nemunaitis, D.F. Andrews, and C.S. Rosenfeld Bone marrow transplant-associated thrombotic microangiopathy: a case series Bone Marrow Transplant. 15 1995 247 253
5. A.R. Pettitt, and R.E. Clark Thrombotic microangiopathy following bone marrow transplantation Bone Marrow Transplant. 14 1994 495 504
6. K.J. Wojno, G.B. Vogelsang, W.E. Beschorner, and G.W. Santos Pulmonary hemorrhage as a cause of death in allogenic bone marrow recipients with severe acute graft-versus-host disease Transplantation 57 1994 88 92
7. C. Agusti, J. Ramirez, C. Picado, A. Xaubet, E. Carreras, and E. Ballester Diffuse alveolar hemorrhage in allogenic bone marrow transplantation. A postmortem study Am. J. Respir. Crit. Care Med. 151 1995 1006 1010
8. S.T. Crooke, and W.T. Bradner Mitomycin C: a review Cancer Treat. Rev. 3 1976 121 139
9. W. Szybalski, and V.N. Iyer Crosslinking of DNA by enzymatically or chemically activated mitomycins and porfiromycins, bifunctionally "alkylating" antibiotics Fed. Proc. 23 1964 946 957
10. A.M. Dulhanty, M. Li, and G.F. Whitmore Isolation of Chinese hamster ovary cell mutants deficient in excision repair and mitomycin C bioactivation Cancer Res. 49 1989 117 122
11. K.H. Antman, A.T. Skarin, R.J. Mayer, H.K. Hargreaves, and G.P. Canellos Microangiopathic hemolytic anemia and cancer: a review Medicine 58 1979 377 384
12. R. Sheldon, and D. Slaughter A syndrome of microangiopathic hemolytic anemia, renal impairment, and pulmonary edema in chemotherapy-treated patients with adenocarcinoma Cancer 58 1986 1428 1436
13. S.C. Gulati, P. Sordillo, S. Kempin, L. Reich, G.B. Magill, and E. Scheiner Microangiopathic hemolytic anemia observed after treatment of epidermoid carcinoma with mitomycin C and 5-fluorouracil Cancer 45 1980 2252 2257
14. I.D. Lewis, T. DeFor, and D.J. Weisdorf Increasing incidence of diffuse alveolar hemorrhage following allogeneic bone marrow transplantation: cryptic etiology and uncertain therapy Bone Marrow Transplant. 26 5 2000 539 543
15. D. Mitra, E.A. Jaffe, B. Weksler, K.A. Hajjar, C. Soderland, and J. Laurence Thrombotic thrombocytopenic purpura (TTP) and adult/sporadic hemolytic-uremic syndrome (HUS) plasma induce apoptosis in restricted lineage of human microvascular endothelial cells Blood 89 1997 1224 1234
16. P.W. Collins, C.N. Gutteridge, A. O'Driscoll, S. Blair, L. Jones, and R. Aitchison von Willebrand factor as a marker of endothelial cell activation following BMT Bone Marrow Transplant. 10 1992 499 506
17. P. Collins, M. Wilkie, K. Razak, S. Abbot, S. Harley, and C. Bax Cyclosporine and cremaphor modulate von Willebrand factor release from cultured human endothelial cells Transplantation 56 1993 1218 1223
18. S. Richard, M. Seigneur, A. Blann, R. Adams, M. Renard, and M. Puntous Vascular endothelial lesion in patients undergoing bone marrow transplantation Bone Marrow Transplant. 18 1996 955 959
19. H. Takatsuka, Y. Takemoto, T. Okamoto, Y. Fujimori, A. Suehiro, and E. Kakishita The levels of soluble P-selectin, von Willebrand factor and thrombomodulin in patients with neurological complications after allogeneic bone marrow transplantation Bone Marrow Transplant. 21 1998 809 813
20. K. Toba, E.F. Winton, T. Koike, and A. Shibata Simultaneous three-color analysis of the surface phenotype and DNA-RNA quantitation using 7-amino-actinomysin D and pyronin Y J. Immunol. Methods 182 1995 193 207
21. K. Toba, E.F. Winton, and R. Bray Improved staining method for the simultaneous flow cytofluorometric analysis of DNA content, S-phase fraction, and surface phenotype using single laser instrumentation Cytometry 13 1992 60 67
22. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
23. D.S. Beardsley, J.E. Spiegel, M.M. Jacobs, R.I. Handin, and S.E. Lux Platelet membrane glycoprotein IIa contains target antigens that bind anti-platelet antibodies in immune thrombocytopenia J. Clin. Invest. 74 1984 1701 1707
24. T.L. Yue, P.J. McKenna, J.L. Gu, H.Y. Cheng, R.E. Ruffolo Jr., and G.Z. Feuerstein Carvedilol, a new vasodilating beta adrenoceptor blocker antihypertensive drug, protects endothelial cells from damage initiated by xanthine-xanthine oxidase and neutrophils Cardiovasc. Res. 28 1994 400 406
25. H. Ishii, M. Nakano, J. Tsubouchi, T. Ishikawa, H. Uchiyama, and S. Hiraishi Establishment of enzyme immunoassay of human thrombomodulin in plasma and urine using monoclonal antibodies Thromb. Haemost. 63 1990 157 162
26. A. Almasan, S.P. Linke, T.G. Paulson, L.C. Huang, and G.M. Wahl Genetic instability as a consequence of inappropriate entry into and progression through S-phase Cancer Metastasis Rev. 14 1995 59 73
27. L. Delavaine, and N.B. La Thangue Control of E2F activity by p21 Waf1/Cip1 Oncogene 18 1999 5381 5392
28. T. Karashima, H. Hachisuka, and Y. Sasai FK506 and cyclosporin A inhibit growth factor-stimulated human keratinocyte proliferation by blocking cells in the G0/G1 phase of the cell cycle J. Dermatol. Sci. 12 1996 246 254
29. F. Dolbeare, H. Gratzner, M.G. Pallavicini, and J.W. Gray Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine Proc. Natl. Acad. Sci. U. S. A. 80 1983 5573 5577
30. R. Moran, Z. Darzynkiewicz, L. Staiano-Coico, and M.R. Melamed Detection of 5-Bromodeoxyuridine (BrdUrd) incorporation by monoclonal antibodies: role of the DNA denaturation step J. Histochem. Cytochem. 33 1985 821 827
31. B. Schutte, M.M.J. Reynders, C.L.M.V.J. van Assche, P.S. Hupperets, F.T. Bosman, and G.H. Blijham An improved method for the immunocytochemical detection of bromodeoxyuridine labeled nuclei using flow cytometry Cytometry 8 1987 372 376
32. D.J. Riley, E.Y. Lee, and W.H. Lee The retinoblastoma protein: more than a tumor suppressor Cell Biol. 10 1994 1 29
33. R.E. Hollingsworth, P.L. Chen, and W.H. Lee Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein Curr. Opin. Cell Biol. 5 1993 194 200
34. C. Cordon-Cardo, G. Dalbagni, and V.M. Richon Significance of the retinoblastoma gene in human cancer Princ. Pract. Oncol. 6 1992 1 9
35. D.M. Livingston Functional analysis of the retinoblastoma gene product and of Rb-SV40T antigen complexes Cancer Surv. 12 1992 153 160
36. N.L. Esmon Thrombomodulin Semin. Thromb. Hemost. 13 1987 454 463
37. H.V. Jakubowski, M.D. Kline, and W.G. Owen The effect of bovine thrombomodulin on the specificity of bovine thrombin J. Biol. Chem. 261 1986 3876 3882
38. C.T. Esmon The roles of protein C and thrombomodulin in the regulation of blood coagulation J. Biol. Chem. 264 1989 4743 4746
39. W.A. Dittman, and P.W. Majerus Structure and function of thrombomodulin: a natural anticoagulant Blood 75 1990 329 336
40. K. Suzuki, H. Kusumoto, Y. Deyashiki, J. Nishioka, I. Maruyama, and M. Zushi Structure and expression of human thrombomodulin, a thrombin receptor on endothelium actina as a cofactor for protein C activation EMBO J. 6 1987 1891 1897
41. H. Ishii, H. Uchiyama, and M. Kazama Soluble thrombomodulin antigen in conditioned medium is increased by damage of endothelial cells Thromb. Haemost. 65 1991 618 623
42. C. Zoja, L. Furci, F. Ghilardi, P. Zilio, A. Benigni, and G. Remuzzi Cyclosporin-induced endothelial cell injury Lab. Invest. 55 1986 455 462
43. A. Benigni, M. Morigi, N. Perico, C. Zoja, C.S. Amuchastegui, and A. Piccinelli The acute effect of FK506 and cyclosporine of endothelial cell function and renal vascular resistance Transplantation 54 1992 775 780
44. P. Roberts, D. Follette, R. Allen, S. Katznelson, and T. Albertson Cyclosporin A-associated thrombotic thrombocytopenic purpura following lung transplantation Transplant. Proc. 30 1988 1512 1513
45. R.L. Paquette, L. Tran, and E.M. Landaw Thrombotic microangiopathy following allogenic bone marrow transplantation is associated with intensive graft-versus-host disease prophylaxis Bone Marrow Transplant. 22 1998 351 357
46. J.P. Hand, E.R. Lawlor, C.K. Young, and J.H. Davis Successful use of cyclosporine A in the treatment of refractory thrombocytopenic purpura Br. J. Haematol. 100 1998 597 599
47. D. Pasquale, R. Vidhya, K. DaSilva, M.F. Tsan, L. Lansing, and G. Chikkappa Chronic relapsing thrombocytopenic purpura: role of therapy with cyclosporine Am. J. Hematol. 57 1998 57 61