Enrichment of n-3 polyunsaturated fatty acids into acylglycerols of borage oil via lipase-catalyzed reactions under supercritical conditions

Chemical Engineering Journal

Volumn 141, Issue 1-3, 2008, Pages 318-326

  Lin, Tsao Jen ^a   Chen, Shin Wan ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

Author keywords

Enzyme technology; n 3 polyunsaturated fatty acid; Production kinetics; Supercritical fluid; Trans esterification

Indexed keywords

CARBON DIOXIDE; CATALYST ACTIVITY; ESTERIFICATION; PARAMETER ESTIMATION; SUPERCRITICAL FLUIDS;

ENZYME TECHNOLOGY; PRODUCTION KINETICS; TRANS-ESTERIFICATION;

FATTY ACIDS;

CARBON DIOXIDE; CATALYST ACTIVITY; ESTERIFICATION; FATTY ACIDS; PARAMETER ESTIMATION; SUPERCRITICAL FLUIDS;

BORAGINACEAE; MUCOR; RHIZOMUCOR MIEHEI;

EID: 44749093041     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2008.01.029     Document Type: Article

References (34)

1. Horrobin D.F., and Bennett C.N. Depression and bipolar disorder: relationships to impaired fatty acid and phospholipid metabolism and to diabetes, cardiovascular disease, immunological abnormalities, cancer, ageing and osteoporosis. Possible candidate genes. Prostaglandins Leukot. Essent. Fatty Acids 60 (1999) 217-234
2. Horrobin D.F., and Bennett C.N. New gene targets related to schizophrenia and other psychiatric disorders: enzymes, binding proteins and transport proteins involved in phospholipid and fatty acid metabolism. Prostaglandins Leukot. Essent. Fatty Acids. 60 (1999) 141-167
3. Gunstone F.D. Gamma-linolenic acid occurrence and physical and chemical properties. Prog. Lipid Res. 31 (1992) 145-163
4. Fan Y.Y., and Chapkin R.S. Importance of dietary gamma-linolenic acid in human health and nutrition. J. Nutr. 128 (1998) 1411-1414
5. Bracelli U.O., Weiss M., Beach D., Motz A., and Thompson B. High linoleic acid diets ameliorate diabetic nephropathy in rats. Am. J. Kidney Dis. 16 (1990) 244-251
6. Deferne J.-L., and Leeds A.R. The antihypertensive effects of dietary supplementation with a 6-desaturated essential fatty acid concentrate as compared with sunflower seed oil. J. Hum. Hpertens. 6 (1992) 113-119
7. Kunkel S.L., Ogawa H., Ward P.A., and Zurier R.B. Supression of chronic inflammation by evening primrose oil. Prog. Lipid Res. 20 (1981) 885-888
8. Jensen G.L., and Jensen R.G. Specialty lipids for infant nutrition ii concern, new developments, and future applications. J. Pediatr. Gastroentr. Nutr. 15 (1992) 382-394
9. Kinsella J.E. Food lipids and fatty acids: importance in food quality, nutrition, and health. Food Technol. 42 (1988) 124-145
10. Yehuda S., and Carasso R.L. Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified α-linolenic and linoleic acids: determination of the optional ω3-to-ω6 ratio. Proc. Natl. Acad. Sci. USA 90 (1993) 10345-10349
11. Horrobin D.F., and Manku M.S. In: Horrobin D.F., Alan R., and Liss (Eds). Clinical Biochemistry of Essential Fatty Acids, in Omega-6 Essential Fatty Acid: Pathophysiology and Roles in Clinical Medicine (1990), Inc., New York 21-53
12. Lawson L.D., and Hughes B.G. Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters. Biochem. Biophys. Res. Commun. 152 (1988) 328-335
13. Huang K.H., and Akoh C.C. Lipase-catalyzed incorporation of n-3 polyunsaturated fatty acids into vegetable oils. JAOCS 71 (1994) 1277-1280
14. Lin T.-J., Chen S.-W., and Chang A.-C. Enrichment of n-3 PUFA contents on triglycerides of fish oil by lipase-catalyzed trans-esterification under supercritical conditions. Biochem. Eng. J. 29 (2006) 27
15. Ju Y.-H., Huang F.-C., and Fang C.-H. The incorporation of n-3 polyunsaturated fatty acids into acylglycerols of borage oil via lipase-catalyzed reactions. JAOCS 75 (1998) 961-965
16. Akoh C.C., Jennings B.H., and Lillard D.A. Enzymatic modification of evening primrose oil: incorporation of n-3 poly-unsaturated fatty acids. JAOCS 73 (1996) 1059-1062
17. Jackson M.A., King J.W., List G.R., and Neff W.E. Lipase-catalyzed randomization of fats and oils in flowing supercritical carbon dioxide. JAOCS 74 (1997) 635-639
18. Knez Z., Habulin M., and Krmelj V. Enzyme catalyzed reactions in dense gases. J. Supercrit. Fluids 14 (1998) 17-29
19. Ekart M.P., Bennett K.L., Ekart S.M., Gurdial G.S., Liotta C.L., and Eckert C.A. Co-solvent interactions in supercritical fluid solutions. AIChE J. 39 (1993) 235-248
20. Dooly K.M., and Becnel J.M. Supercritical fluid extraction of polycyclic aromatic hydrocarbon mixtures from contaminated soils. Ind. Eng. Chem. Res. 37 (1998) 584-590
21. Reyes H.R., and Hill Jr. C.G. Kinetic modeling of interesterification reactions catalyzed by immobilized lipase. Biotechnol. Bioeng. 43 (1994) 171-182
22. Garcia T., Sanchez N., Martinez M., and Aracil J. Enzymatic synthesis of fatty esters part I. Kinetic approach. Enzyme Microb. Technol. 25 (1999) 584-590
23. Mukesh D., Jadhav S., Banerji A.A., Thakkar K., and Bevinakatti H.S. Lipase-catalysed esterification reactions-experimental and modeling studies. J. Chem. Tech. Biotechnol. 69 (1997) 179-186
24. Goddard R., Bosley J., and Al-Duri B. Esterification of oleic acid and ethanol in plug flow (packed bed) reactor under supercritical conditions investigation of kinetics. J. Supercrit. Fluids 18 (2000) 121-130
25. Haagsma H., Luten C.M., vanGen J.B., Jong R.W.D., and Doorn V.E. Preparation of an ω3 fatty acids concentrate from cod liver oil. JAOCS 59 (1982) 117-118
26. Rahmatullah M.S.K.S., Shukla V.K.S., and Mukherjee K.D. Enrichment of γ-linolenic acid from evening primrose oil and borage oil via lipase-catalyzed hydrolysis. JAOCS 71 (1994) 569-573
27. Yamauchi A., Matsuzawa Y., Hara Y., Saishin M., Nishioka K., Nakao S., and Kamiya S. Use of poly(vinyl alcohol) hydrogels as a drug carrier, polymer preprints, division of polymer chemistry. Am. Chem. Soc. 20 (1979) 575-576
28. Senanayake S.P.J.N., and Shahidi F. Enzymatic incorporation of docosahexaenoic acid into borage oil. JAOCS 76 (1999) 1009-1015
29. Zagrobelny J., and Bright F.V. In situ studies of conformation in supercritical fluids: trypsin in carbon dioxide. Biotechnol. Prog. 8 (1992) 421-423
30. Erickson J.C., Schyns P., and Cooney C.L. Effect of pressure on an enzymatic reaction in a supercritical fluid. AIChE J. 36 (1990) 299-301
31. Ikushima Y., Saito N., Hatakeda K., and Sato O. Promotion of a lipase-catalyzed esterification in supercritical carbon dioxide in the near-critical region. Chem. Eng. Sci. 51 (1996) 2817-2822
32. Kamat S., Critchley G., Beckman E.J., and Russell A.J. Biocatalytic synthesis of acylates in organic solvents and supercritical fluids, III. Does carbon dioxide covalently modify enzymes?. Biotechnol. Bioeng. 46 (1995) 610-620
33. Dumont T., Barth D., Corbier C., Branlant G., and Perrut M. Enzymatic reaction kinetic: comparison in an organic solvent and in supercritical carbon dioxide. Biotechnol. Bioeng. 39 (1992) 329-333
34. Segel I.H. Enzyme Kinetics (1975), Wiley, New York pp. 826-829