메뉴 건너뛰기




Volumn 26, Issue 26, 2008, Pages 3261-3267

Active immunisation with RAMA does not provide protective immunity against Plasmodium yoelii challenge despite its association with protective responses in endemic populations

Author keywords

Antibody response; Invasion inhibition; Malaria; Plasmodium; RAMA; Subunit vaccine

Indexed keywords

ECMSP4 5; ECPYRAMA P40; ECPYRAMAE PROTEIN; MALARIA VACCINE; MEROZOITE SURFACE PROTEIN 4; MEROZOITE SURFACE PROTEIN 5; PARASITE ANTIGEN; RECOMBINANT PROTEIN; RHOPTRY ASSOCIATED MEMBRANE ANTIGEN; SUBUNIT VACCINE;

EID: 44749092352     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.04.002     Document Type: Article
Times cited : (4)

References (43)
  • 1
    • 0037033989 scopus 로고    scopus 로고
    • Malaria in 2002
    • Greenwood B., and Mutabingwa T. Malaria in 2002. Nature 415 February 7 (6872) (2002) 670-672
    • (2002) Nature , vol.415 , Issue.February 7 6872 , pp. 670-672
    • Greenwood, B.1    Mutabingwa, T.2
  • 2
    • 33745424178 scopus 로고    scopus 로고
    • Progress towards the development of malaria vaccines
    • Malkin E., Dubovsky F., and Moree M. Progress towards the development of malaria vaccines. Trends Parasitol 22 July (7) (2006) 292-295
    • (2006) Trends Parasitol , vol.22 , Issue.July 7 , pp. 292-295
    • Malkin, E.1    Dubovsky, F.2    Moree, M.3
  • 3
    • 33745401801 scopus 로고    scopus 로고
    • Vaccine development against malaria
    • Matuschewski K. Vaccine development against malaria. Curr Opin Immunol 18 August (4) (2006) 449-457
    • (2006) Curr Opin Immunol , vol.18 , Issue.August 4 , pp. 449-457
    • Matuschewski, K.1
  • 5
    • 0037033980 scopus 로고    scopus 로고
    • Progress and challenges for malaria vaccines
    • Richie T.L., and Saul A. Progress and challenges for malaria vaccines. Nature 415 February 7 (6872) (2002) 694-701
    • (2002) Nature , vol.415 , Issue.February 7 6872 , pp. 694-701
    • Richie, T.L.1    Saul, A.2
  • 6
    • 11444269466 scopus 로고    scopus 로고
    • Vaccine-induced immunity to malaria parasites and the need for novel strategies
    • Good M.F. Vaccine-induced immunity to malaria parasites and the need for novel strategies. Trends Parasitol 21 January (1) (2005) 29-34
    • (2005) Trends Parasitol , vol.21 , Issue.January 1 , pp. 29-34
    • Good, M.F.1
  • 7
    • 0037015614 scopus 로고    scopus 로고
    • Genome sequence of the human malaria parasite Plasmodium falciparum
    • Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 October 3 (6906) (2002) 498-511
    • (2002) Nature , vol.419 , Issue.October 3 6906 , pp. 498-511
    • Gardner, M.J.1    Hall, N.2    Fung, E.3    White, O.4    Berriman, M.5    Hyman, R.W.6
  • 8
    • 4243071596 scopus 로고    scopus 로고
    • The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
    • Bozdech Z., Llinas M., Pulliam B.L., Wong E.D., Zhu J., and DeRisi J.L. The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol 1 October (1) (2003) E5
    • (2003) PLoS Biol , vol.1 , Issue.October 1
    • Bozdech, Z.1    Llinas, M.2    Pulliam, B.L.3    Wong, E.D.4    Zhu, J.5    DeRisi, J.L.6
  • 9
    • 0141633042 scopus 로고    scopus 로고
    • Discovery of gene function by expression profiling of the malaria parasite life cycle
    • Le Roch K.G., Zhou Y., Blair P.L., Grainger M., Moch J.K., Haynes J.D., et al. Discovery of gene function by expression profiling of the malaria parasite life cycle. Science 301 September 12 (5639) (2003) 1503-1508
    • (2003) Science , vol.301 , Issue.September 12 5639 , pp. 1503-1508
    • Le Roch, K.G.1    Zhou, Y.2    Blair, P.L.3    Grainger, M.4    Moch, J.K.5    Haynes, J.D.6
  • 10
    • 0028985140 scopus 로고
    • Transfection of Plasmodium falciparum within human red blood cells
    • Wu Y., Sifri C.D., Lei H.H., Su X.Z., and Wellems T.E. Transfection of Plasmodium falciparum within human red blood cells. Proc Natl Acad Sci U. S. A. 92 February14 (44) (1995) 973-977
    • (1995) Proc Natl Acad Sci U. S. A. , vol.92 , Issue.February14 44 , pp. 973-977
    • Wu, Y.1    Sifri, C.D.2    Lei, H.H.3    Su, X.Z.4    Wellems, T.E.5
  • 11
    • 1042289743 scopus 로고    scopus 로고
    • Characterization of a membrane-associated rhoptry protein of Plasmodium falciparum
    • Topolska A.E., Lidgett A., Truman D., Fujioka H., and Coppel R.L. Characterization of a membrane-associated rhoptry protein of Plasmodium falciparum. J Biol Chem 279 February 6 (6) (2004) 4648-4656
    • (2004) J Biol Chem , vol.279 , Issue.February 6 6 , pp. 4648-4656
    • Topolska, A.E.1    Lidgett, A.2    Truman, D.3    Fujioka, H.4    Coppel, R.L.5
  • 12
    • 8844254777 scopus 로고    scopus 로고
    • Identification and characterisation of RAMA homologues in rodent, simian and human malaria species
    • Topolska A.E., Black C.G., and Coppel R.L. Identification and characterisation of RAMA homologues in rodent, simian and human malaria species. Mol Biochem Parasitol 138 December (2) (2004) 237-241
    • (2004) Mol Biochem Parasitol , vol.138 , Issue.December 2 , pp. 237-241
    • Topolska, A.E.1    Black, C.G.2    Coppel, R.L.3
  • 13
    • 33745630355 scopus 로고    scopus 로고
    • A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion
    • Sanders P.R., Kats L.M., Drew D.R., O'Donnell R.A., O'Neill M., Maier A.G., et al. A set of glycosylphosphatidyl inositol-anchored membrane proteins of Plasmodium falciparum is refractory to genetic deletion. Infect Immunol 74 July (7) (2006) 4330-4338
    • (2006) Infect Immunol , vol.74 , Issue.July 7 , pp. 4330-4338
    • Sanders, P.R.1    Kats, L.M.2    Drew, D.R.3    O'Donnell, R.A.4    O'Neill, M.5    Maier, A.G.6
  • 14
    • 34547758005 scopus 로고    scopus 로고
    • Polymorphism study of rhoptry associated membrane antigen (RAMA) gene of Plasmodium falciparum - a putative vaccine candidate
    • Kar P., Dash A.P., and Supakar P.C. Polymorphism study of rhoptry associated membrane antigen (RAMA) gene of Plasmodium falciparum - a putative vaccine candidate. Mol Biochem Parasitol 155 October (2) (2007) 156-160
    • (2007) Mol Biochem Parasitol , vol.155 , Issue.October 2 , pp. 156-160
    • Kar, P.1    Dash, A.P.2    Supakar, P.C.3
  • 15
    • 23944462968 scopus 로고    scopus 로고
    • Antibodies to rhoptry-associated membrane antigen predict resistance to Plasmodium falciparum
    • Nixon C.P., Friedman J., Treanor K., Knopf P.M., Duffy P.E., and Kurtis J.D. Antibodies to rhoptry-associated membrane antigen predict resistance to Plasmodium falciparum. J Infect Dis 192 September 1 (5) (2005) 861-869
    • (2005) J Infect Dis , vol.192 , Issue.September 1 5 , pp. 861-869
    • Nixon, C.P.1    Friedman, J.2    Treanor, K.3    Knopf, P.M.4    Duffy, P.E.5    Kurtis, J.D.6
  • 16
    • 2542610005 scopus 로고    scopus 로고
    • Associations between responses to the rhoptry-associated membrane antigen of Plasmodium falciparum and immunity to malaria infection
    • Topolska A.E., Richie T.L., Nhan D.H., and Coppel R.L. Associations between responses to the rhoptry-associated membrane antigen of Plasmodium falciparum and immunity to malaria infection. Infect Immunol 72 June (6) (2004) 3325-3330
    • (2004) Infect Immunol , vol.72 , Issue.June 6 , pp. 3325-3330
    • Topolska, A.E.1    Richie, T.L.2    Nhan, D.H.3    Coppel, R.L.4
  • 17
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager W., and Jensen J.B. Human malaria parasites in continuous culture. Science 193 August 20 (4254) (1976) 673-675
    • (1976) Science , vol.193 , Issue.August 20 4254 , pp. 673-675
    • Trager, W.1    Jensen, J.B.2
  • 18
    • 0035908009 scopus 로고    scopus 로고
    • Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria
    • O'Donnell R.A., de Koning-Ward T.F., Burt R.A., Bockarie M., Reeder J.C., Cowman A.F., et al. Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria. J Exp Med 193 June 18 (12) (2001) 1403-1412
    • (2001) J Exp Med , vol.193 , Issue.June 18 12 , pp. 1403-1412
    • O'Donnell, R.A.1    de Koning-Ward, T.F.2    Burt, R.A.3    Bockarie, M.4    Reeder, J.C.5    Cowman, A.F.6
  • 19
    • 0034655621 scopus 로고    scopus 로고
    • Optimisation of flow cytometric measurement of parasitemia in Plasmodium-infected mice
    • Barkan D., Ginsburg H., and Golenser J. Optimisation of flow cytometric measurement of parasitemia in Plasmodium-infected mice. Int J Parasitol 30 April 24 (5) (2000) 649-653
    • (2000) Int J Parasitol , vol.30 , Issue.April 24 5 , pp. 649-653
    • Barkan, D.1    Ginsburg, H.2    Golenser, J.3
  • 20
    • 0033796852 scopus 로고    scopus 로고
    • Immunization with recombinant Plasmodium yoelii merozoite surface protein 4/5 protects mice against lethal challenge
    • Kedzierski L., Black C.G., and Coppel R.L. Immunization with recombinant Plasmodium yoelii merozoite surface protein 4/5 protects mice against lethal challenge. Infect Immunol 68 October (10) (2000) 6034-6037
    • (2000) Infect Immunol , vol.68 , Issue.October 10 , pp. 6034-6037
    • Kedzierski, L.1    Black, C.G.2    Coppel, R.L.3
  • 21
    • 0037407806 scopus 로고    scopus 로고
    • Oral immunization with a recombinant malaria protein induces conformational antibodies and protects mice against lethal malaria
    • Wang L., Kedzierski L., Wesselingh S.L., and Coppel R.L. Oral immunization with a recombinant malaria protein induces conformational antibodies and protects mice against lethal malaria. Infect Immunol 71 May (5) (2003) 2356-2364
    • (2003) Infect Immunol , vol.71 , Issue.May 5 , pp. 2356-2364
    • Wang, L.1    Kedzierski, L.2    Wesselingh, S.L.3    Coppel, R.L.4
  • 22
    • 4644254980 scopus 로고    scopus 로고
    • Oral immunization with a combination of Plasmodium yoelii merozoite surface proteins 1 and 4/5 enhances protection against lethal malaria challenge
    • Wang L., Goschnick M.W., and Coppel R.L. Oral immunization with a combination of Plasmodium yoelii merozoite surface proteins 1 and 4/5 enhances protection against lethal malaria challenge. Infect Immunol 72 October (10) (2004) 6172-6175
    • (2004) Infect Immunol , vol.72 , Issue.October 10 , pp. 6172-6175
    • Wang, L.1    Goschnick, M.W.2    Coppel, R.L.3
  • 23
    • 0035860623 scopus 로고    scopus 로고
    • Comparison of the protective efficacy of yeast-derived and Escherichia coli-derived recombinant merozoite surface protein 4/5 against lethal challenge by Plasmodium yoelii
    • Kedzierski L., Black C.G., Stowers A.W., Goschnick M.W., Kaslow D.C., and Coppel R.L. Comparison of the protective efficacy of yeast-derived and Escherichia coli-derived recombinant merozoite surface protein 4/5 against lethal challenge by Plasmodium yoelii. Vaccine 19 September 14 (32) (2001) 4661-4668
    • (2001) Vaccine , vol.19 , Issue.September 14 32 , pp. 4661-4668
    • Kedzierski, L.1    Black, C.G.2    Stowers, A.W.3    Goschnick, M.W.4    Kaslow, D.C.5    Coppel, R.L.6
  • 24
    • 0036892169 scopus 로고    scopus 로고
    • Immunization with a combination of merozoite surface proteins 4/5 and 1 enhances protection against lethal challenge with Plasmodium yoelii
    • Kedzierski L., Black C.G., Goschnick M.W., Stowers A.W., and Coppel R.L. Immunization with a combination of merozoite surface proteins 4/5 and 1 enhances protection against lethal challenge with Plasmodium yoelii. Infect Immunol 70 December (12) (2002) 6606-6613
    • (2002) Infect Immunol , vol.70 , Issue.December 12 , pp. 6606-6613
    • Kedzierski, L.1    Black, C.G.2    Goschnick, M.W.3    Stowers, A.W.4    Coppel, R.L.5
  • 25
    • 4644240199 scopus 로고    scopus 로고
    • Merozoite surface protein 4/5 provides protection against lethal challenge with a heterologous malaria parasite strain
    • Goschnick M.W., Black C.G., Kedzierski L., Holder A.A., and Coppel R.L. Merozoite surface protein 4/5 provides protection against lethal challenge with a heterologous malaria parasite strain. Infect Immunol 72 October (10) (2004) 5840-5849
    • (2004) Infect Immunol , vol.72 , Issue.October 10 , pp. 5840-5849
    • Goschnick, M.W.1    Black, C.G.2    Kedzierski, L.3    Holder, A.A.4    Coppel, R.L.5
  • 26
    • 0033621745 scopus 로고    scopus 로고
    • Characterization of the merozoite surface protein 4/5 gene of Plasmodium berghei and Plasmodium yoelii
    • Kedzierski L., Black C.G., and Coppel R.L. Characterization of the merozoite surface protein 4/5 gene of Plasmodium berghei and Plasmodium yoelii. Mol Biochem Parasitol 105 January 5 (1) (2000) 137-147
    • (2000) Mol Biochem Parasitol , vol.105 , Issue.January 5 1 , pp. 137-147
    • Kedzierski, L.1    Black, C.G.2    Coppel, R.L.3
  • 27
    • 33746273843 scopus 로고    scopus 로고
    • Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargeant T, Speed TP, et al. Identification and stoichiometry of GPI-anchored membrane proteins of the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics 2006; (April 7).
    • Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargeant T, Speed TP, et al. Identification and stoichiometry of GPI-anchored membrane proteins of the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics 2006; (April 7).
  • 28
    • 0032929401 scopus 로고    scopus 로고
    • Identification of the Plasmodium chabaudi homologue of merozoite surface proteins 4 and 5 of Plasmodium falciparum
    • Black C.G., Wang L., Hibbs A.R., Werner E., and Coppel R.L. Identification of the Plasmodium chabaudi homologue of merozoite surface proteins 4 and 5 of Plasmodium falciparum. Infect Immunol 67 May (5) (1999) 2075-2081
    • (1999) Infect Immunol , vol.67 , Issue.May 5 , pp. 2075-2081
    • Black, C.G.1    Wang, L.2    Hibbs, A.R.3    Werner, E.4    Coppel, R.L.5
  • 29
    • 0031984944 scopus 로고    scopus 로고
    • Analysis of inhibitory epitopes in the Plasmodium falciparum rhoptry protein RAP-1 including identification of a second inhibitory epitope
    • Howard R.F., Jacobson K.C., Rickel E., and Thurman J. Analysis of inhibitory epitopes in the Plasmodium falciparum rhoptry protein RAP-1 including identification of a second inhibitory epitope. Infect Immunol 66 January (1) (1998) 380-386
    • (1998) Infect Immunol , vol.66 , Issue.January 1 , pp. 380-386
    • Howard, R.F.1    Jacobson, K.C.2    Rickel, E.3    Thurman, J.4
  • 30
    • 0025151477 scopus 로고
    • A rhoptry antigen of Plasmodium falciparum is protective in Saimiri monkeys
    • Ridley R.G., Takacs B., Etlinger H., and Scaife J.G. A rhoptry antigen of Plasmodium falciparum is protective in Saimiri monkeys. Parasitology 101 October (Pt 2) (1990) 187-192
    • (1990) Parasitology , vol.101 , Issue.October PART 2 , pp. 187-192
    • Ridley, R.G.1    Takacs, B.2    Etlinger, H.3    Scaife, J.G.4
  • 31
    • 0021680399 scopus 로고
    • The Fab fragments of monoclonal IgG to a merozoite surface antigen inhibit Plasmodium knowlesi invasion of erythrocytes
    • Thomas A.W., Deans J.A., Mitchell G.H., Alderson T., and Cohen S. The Fab fragments of monoclonal IgG to a merozoite surface antigen inhibit Plasmodium knowlesi invasion of erythrocytes. Mol Biochem Parasitol 13 October (2) (1984) 187-199
    • (1984) Mol Biochem Parasitol , vol.13 , Issue.October 2 , pp. 187-199
    • Thomas, A.W.1    Deans, J.A.2    Mitchell, G.H.3    Alderson, T.4    Cohen, S.5
  • 32
    • 0019975873 scopus 로고
    • Rat monoclonal antibodies which inhibit the in vitro multiplication of Plasmodium knowlesi
    • Deans J.A., Alderson T., Thomas A.W., Mitchell G.H., Lennox E.S., and Cohen S. Rat monoclonal antibodies which inhibit the in vitro multiplication of Plasmodium knowlesi. Clin Exp Immunol 49 August (2) (1982) 297-309
    • (1982) Clin Exp Immunol , vol.49 , Issue.August 2 , pp. 297-309
    • Deans, J.A.1    Alderson, T.2    Thomas, A.W.3    Mitchell, G.H.4    Lennox, E.S.5    Cohen, S.6
  • 33
    • 0031986201 scopus 로고    scopus 로고
    • Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi
    • Anders R.F., Crewther P.E., Edwards S., Margetts M., Matthew M.L., Pollock B., et al. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi. Vaccine 16 January-February (2-3) (1998) 240-247
    • (1998) Vaccine , vol.16 , Issue.January-February 2-3 , pp. 240-247
    • Anders, R.F.1    Crewther, P.E.2    Edwards, S.3    Margetts, M.4    Matthew, M.L.5    Pollock, B.6
  • 34
    • 0020383019 scopus 로고
    • Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody
    • Holder A.A., and Freeman R.R. Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody. J Exp Med 156 November 1 (5) (1982) 1528-1538
    • (1982) J Exp Med , vol.156 , Issue.November 1 5 , pp. 1528-1538
    • Holder, A.A.1    Freeman, R.R.2
  • 35
    • 0021222163 scopus 로고
    • The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor
    • Holder A.A., and Freeman R.R. The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor. J Exp Med 160 August 1 (2) (1984) 624-629
    • (1984) J Exp Med , vol.160 , Issue.August 1 2 , pp. 624-629
    • Holder, A.A.1    Freeman, R.R.2
  • 36
    • 0028145547 scopus 로고
    • Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites
    • Narum D.L., and Thomas A.W. Differential localization of full-length and processed forms of PF83/AMA-1 an apical membrane antigen of Plasmodium falciparum merozoites. Mol Biochem Parasitol 67 September (1) (1994) 59-68
    • (1994) Mol Biochem Parasitol , vol.67 , Issue.September 1 , pp. 59-68
    • Narum, D.L.1    Thomas, A.W.2
  • 37
    • 0036784706 scopus 로고    scopus 로고
    • Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites
    • Healer J., Crawford S., Ralph S., McFadden G., and Cowman A.F. Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites. Infect Immunol 70 October (10) (2002) 5751-5758
    • (2002) Infect Immunol , vol.70 , Issue.October 10 , pp. 5751-5758
    • Healer, J.1    Crawford, S.2    Ralph, S.3    McFadden, G.4    Cowman, A.F.5
  • 38
    • 33846837329 scopus 로고    scopus 로고
    • High road, low road? Choices and challenges on the pathway to a malaria vaccine
    • Richie T. High road, low road? Choices and challenges on the pathway to a malaria vaccine. Parasitology 133 October (Suppl.) (2006) S113-S144
    • (2006) Parasitology , vol.133 , Issue.October SUPPL.
    • Richie, T.1
  • 39
    • 0023143240 scopus 로고
    • Kinetic constraints on the development of a malaria vaccine
    • Saul A. Kinetic constraints on the development of a malaria vaccine. Parasite Immunol 9 January (1) (1987) 1-9
    • (1987) Parasite Immunol , vol.9 , Issue.January 1 , pp. 1-9
    • Saul, A.1
  • 40
    • 0344717267 scopus 로고    scopus 로고
    • Antibodies that inhibit malaria merozoite surface protein-1 processing and erythrocyte invasion are blocked by naturally acquired human antibodies
    • Guevara Patino J.A., Holder A.A., McBride J.S., and Blackman M.J. Antibodies that inhibit malaria merozoite surface protein-1 processing and erythrocyte invasion are blocked by naturally acquired human antibodies. J Exp Med 186 November 17 (10) (1997) 1689-1699
    • (1997) J Exp Med , vol.186 , Issue.November 17 10 , pp. 1689-1699
    • Guevara Patino, J.A.1    Holder, A.A.2    McBride, J.S.3    Blackman, M.J.4
  • 41
    • 0036716487 scopus 로고    scopus 로고
    • The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies
    • Nwuba R.I., Sodeinde O., Anumudu C.I., Omosun Y.O., Odaibo A.B., Holder A.A., et al. The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies. Infect Immunol 70 September (9) (2002) 5328-5331
    • (2002) Infect Immunol , vol.70 , Issue.September 9 , pp. 5328-5331
    • Nwuba, R.I.1    Sodeinde, O.2    Anumudu, C.I.3    Omosun, Y.O.4    Odaibo, A.B.5    Holder, A.A.6
  • 42
    • 20444456247 scopus 로고    scopus 로고
    • Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5
    • Wang L., Kedzierski L., Schofield L., and Coppel R.L. Influence of glycosylphosphatidylinositol anchorage on the efficacy of DNA vaccines encoding Plasmodium yoelii merozoite surface protein 4/5. Vaccine 23 July 14 (432) (2005) 4120-4127
    • (2005) Vaccine , vol.23 , Issue.July 14 432 , pp. 4120-4127
    • Wang, L.1    Kedzierski, L.2    Schofield, L.3    Coppel, R.L.4
  • 43
    • 33845576104 scopus 로고    scopus 로고
    • AAV vectors encoding malarial antigens stimulate antigen-specific immunity but do not protect from parasite infection
    • Logan G.J., Wang L., Zheng M., Cunningham S.C., Coppel R.L., and Alexander I.E. AAV vectors encoding malarial antigens stimulate antigen-specific immunity but do not protect from parasite infection. Vaccine 25 January 22 (26) (2007) 1014-1022
    • (2007) Vaccine , vol.25 , Issue.January 22 26 , pp. 1014-1022
    • Logan, G.J.1    Wang, L.2    Zheng, M.3    Cunningham, S.C.4    Coppel, R.L.5    Alexander, I.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.