Immunization with recombinant Plasmodium yoelii merozoite surface protein 4/5 protects mice against lethal challenge

Infection and Immunity

Volumn 68, Issue 10, 2000, Pages 6034-6037

  Kedzierski, L ^a   Black, C G ^a   Coppel, R L ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MEROZOITE SURFACE PROTEIN 4/5; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNIZATION; INFECTION PREVENTION; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM YOELII; PRIORITY JOURNAL; PROTOZOAL INFECTION;

ANIMAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; FEMALE; MALARIA; MALARIA VACCINES; MICE; MICE, INBRED BALB C; PARASITEMIA; PLASMODIUM YOELII; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; VACCINATION;

EID: 0033796852     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.10.6034-6037.2000     Document Type: Article

References (26)

1. Immunoglobulin G2a isotype may have a protective role in Plasmodium berghei NK65 infection in immunised mice
2. Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi
3. Candidate antigens for an asexual blood stage vaccine against falciparum malaria
4. Identification of the Plasmodium chabaudi homologue of merozoite surface proteins 4 and 5 of Plasmodium falciparum
5. Plasmodium yoelii: The role of the individual epidermal growth factor-like domains of the merozoite surface protein-1 in protection from malaria
6. Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes
7. Humoral response to a carboxyl-terminal region of the merozoite surface protein-1 plays a predominant role in controlling blood-stage infection in rodent malaria
8. A recombinant 15-kilodalton carboxyl-terminal fragment of Plasmodium yoelii yoelii 17XL merozoite surface protein 1 induces a protective immune response in mice
9. Immune effector mechanisms in malaria
10. Involvement of T cells in malaria immunity: Implications for vaccine development
11. Characterization of the merozoite surface protein 4/5 gene of Plasmodium berghei and Plasmodium yoelii
12. The immune response to the blood stages of Plasmodium in animal models
13. The combined epidermal growth factor-like modules of Plasmodium yoelii merozoite surface protein-1 are required for a protective immune response to the parasite
14. Immunization against malaria with a recombinant protein
15. A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factor-like domain
16. Close linkage of three merozoite surface protein genes on chromosome 2 of Plasmodium falciparum
17. Immunization with a recombinant C-terminal fragment of Plasmodium yoelii merozoite surface protein 1 protects mice against homologous but not heterologous P. yoelii sporozoite challenge
18. Plasmodium: Immunization with carboxyl-terminal regions of MSP-1 protects against homologous but not heterologous blood-stage parasite challenge
19. Role of natural killer cells in innate resistance to protozoan infections
20. γδ T cells contribute to control of chronic parasitemia in Plasmodium chabaudi infections in mice
21. The spleen, IgG antibody subsets and immunity to Plasmodium berghei in rats
22. Passive immunization with antibodies against three distinct epitopes on Plasmodium yoelii merozoite surface protein 1 suppresses parasitemia
23. Comparison of protection induced by immunization with recombinant proteins from different regions of merozoite surface protein 1 of Plasmodium yoelii
24. Structural and antigenic properties of merozoite surface protein 4 of Plasmodium falciparum
25. Heat-labile IgG2a antibodies affect cure of Trypanosoma musculi infection in C57BL/6 mice
26. Antimalarial aritibodies of the immunoglobulin G2a isotype modulate parasitemias in mice infected with Plasmodium yoelii