Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate

ChemBioChem

Volumn 9, Issue 7, 2008, Pages 1024-1028

  Barends, Thomas R M ^a   Domratcheva, Tatiana ^a   Kulik, Victor ^a   Blumenstein, Lars ^a   Niks, Dimitri ^b   Dunn, Michael F ^b   Schlichting, Ilme ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allosterism; Enzyme catalysis; Protein structures; Reactive intermediates; Structure activity relationships

Indexed keywords

ACRYLIC ACID; ALPHA AMINOACRYLATE; DIHYDROPTERIDINE REDUCTASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYDROXYL GROUP; INDOLE; METAL; TRYPTOPHAN SYNTHASE; UNCLASSIFIED DRUG; PYRIDOXAL 5 PHOSPHATE;

ALPHA CHAIN; ARTICLE; BIOMIMETICS; CHEMICAL STRUCTURE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTON TRANSPORT; ALLOSTERISM; BINDING SITE; CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM;

ALLOSTERIC REGULATION; BINDING SITES; CATALYTIC DOMAIN; MODELS, MOLECULAR; PYRIDOXAL PHOSPHATE; TRYPTOPHAN SYNTHASE;

EID: 44749089973     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700703     Document Type: Article

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