Characterization of the mechanism of zidovudine uptake by rat conditionally immortalized syncytiotrophoblast cell line TR-TBT

Pharmaceutical Research

Volumn 25, Issue 7, 2008, Pages 1647-1653

  Sai, Y ^a   Nishimura, T ^a   Shimpo, S ^a   Chishu, T ^a   Sato, K ^a   Kose, N ^a   Terasaki, T ^b,c   Mukai, C ^d   Kitagaki, S ^d   Miyakoshi, N ^d   Kang, Y S ^e   Nakashima, E ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

^e Sookmyung Women's University   (South Korea)

Author keywords

AZT; Blood placenta barrier; Syncytiotrophoblast; TR TBT; Transporter

Indexed keywords

CIMETIDINE; CYCLOSPORIN A; DEOXYURIDINE DERIVATIVE; NITROBENZYLTHIOINOSINE; NUCLEOSIDE TRANSPORTER; ORGANIC ANION TRANSPORTER 2; ORGANIC CATION TRANSPORTER; PROBENECID; THYMIDINE; ZIDOVUDINE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL IMMORTALIZATION; CELL LINE; DRUG ACCUMULATION; DRUG INHIBITION; DRUG UPTAKE; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; RAT; STEADY STATE; SYNCYTIOTROPHOBLAST;

ALGORITHMS; ANIMALS; ANTI-HIV AGENTS; CELL LINE; CELL MEMBRANE; DATA INTERPRETATION, STATISTICAL; DRUG INTERACTIONS; GIANT CELLS; NUCLEOSIDE TRANSPORT PROTEINS; ORGANIC ANION TRANSPORTERS; ORGANIC CATION TRANSPORT PROTEINS; RATS; TROPHOBLASTS; ZIDOVUDINE;

EID: 44749089831     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9564-9     Document Type: Article

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