Expression of cellular prion protein (PrPc) in schizophrenia, bipolar disorder, and depression

Journal of Neural Transmission

Volumn 115, Issue 5, 2008, Pages 761-771

  Weis, Serge ^a,b   Haybaeck, Johannes ^c   Dulay, Jeannette R ^a   Llenos, Ida C ^a,b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b State Neuropsychiatric Hopsital Wagner Jauregg   (Austria)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Bipolar disorder; Cellular prion protein; Major depression; Schizophrenia

Indexed keywords

PRION PROTEIN;

ADULT; AGED; ARTICLE; BIPOLAR DISORDER; CINGULATE GYRUS; CLINICAL ARTICLE; DEPRESSION; FEMALE; GLIA CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHIZOPHRENIA; WHITE MATTER;

ADULT; AGED; BIPOLAR DISORDER; BRAIN; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROGLIA; NEURONS; POSTMORTEM CHANGES; PRPC PROTEINS; SCHIZOPHRENIA; STATISTICS, NONPARAMETRIC;

EID: 44749086792     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0013-4     Document Type: Article

References (63)

1. Aguzzi A, Polymenidou M (2004) Mammalian prion biology: one century of evolving concepts. Cell 116:313-327
2. Arnold SE, Trojanowski JQ, Parchi P (1999) Protease resistant prion proteins are not present in sporadic "poor outcome" schizophrenia. J Neurol Neurosurg Psychiatr 66:90-92
3. Brown DR, Schmidt B, Kretzschmar HA (1997a) Effects of oxidative stress on prion protein expression in PC12 cells. Int J Dev Neurosci 15:961-972
4. Brown DR, Schulz-Schaeffer WJ, Schmidt B, Kretzschmar HA (1997b) Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol 146:104-112
5. Brown DR, Besinger A, Herms JW, Kretzschmar HA (1998) Microglial expression of the prion protein. Neuroreport 9:1425-1429
6. Brown DR, Wong BS, Hafiz F, Clive C, Haswell SJ, Jones IM (1999) Normal prion protein has an activity like that of superoxide dismutase. Biochem J 344:1-5
7. Brown DR (2001) Prion and prejudice: normal protein and the synapse. Trends Neurosci 24:85-90
8. Brown DR (2004) Role of the prion protein in copper turnover in astrocytes. Neurobiol Dis 15:534-543
9. Butowt R, Abdelraheim S, Brown DR, von Bartheld CS (2005) Anterograde axonal transport of the exogenous cellular isoform of prion protein in the chick visual system. Mol Cell Neurosci 31:97-108
10. Carter CJ (2006) Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability. Schizophr Res 86:1-14
11. Cashman NR, Loertscher R, Nalbantoglu J, Shaw I, Kascsak RJ, Bolton DC, Bendheim PE (1990) Cellular isoform of the scrapie agent protein participates in lymphocyte activation, Cell 61:185-192
12. Caughey B, Race RE, Chesebro B (1988) Detection of prion protein mRNA in normal and scrapie-infected tissues and cell lines. J Gen Virol 69:711-716
13. Caughey B, Baron GS (2006) Prions and their partners in crime. Nature 443:803-810
14. Chesebro B, Race R, Wehrly K (1985) Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brains. Nature 315:331-333
15. Chong ZZ, Li F, Maiese K (2005) Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Progr Neurobiol 75:207-246
16. DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB (1987) Changes in the localization of brain prion proteins during scrapie infection. Neurology 37:1271-1280
17. Dodelet VC, Cashman NR (1998) Prion protein expression in human leukocyte differentiation. Blood 91:1556-1561
18. Fendri C, Mechri A, Khiari G, Othman A, Kerkeni A, Gaha L (2006) Oxidative stress involvement in schizophrenia pathophysiology: a review. Encephale 32:244-252
19. Ferrer I, Blanco R, Carmona M, Puig B, Ribera R, Rey MJ, Ribalta T (2001) Prion protein expression in senile plaques in Alzheimer's disease. Acta Neuropathol 101:49-56
20. Forman HJ (1997) Oxidative stress and signal transduction. Springer, Heidelberg
21. Gundersen HJG (1977) Notes on the estimation of the numerical density of arbitrary profiles: the edge effects. J Microsc 111:219-223
22. Harrison PJ, Roberts GW (eds) (2000) The neuropathology of schizophrenia. Oxford University Press, Oxford
23. Haug H (1986) History of neuromorphometry. J Neurosci Methods 18:1-17
24. Haug H, Kühl S, Mecke E, Sass N, Wasner K (1984) The significance of morphometric procedures in the investigation of age changes in cytoarchtectonic structures of human brain. J Hirnforsch 25:353-374
25. Kitamoto T, Muramoto T, Mohri S, Doh-Ura K, Tateishi J (1991) Abnormal isoform of prion protein accumulates in follicular dendritic cells in mice with Creutzfeldt-Jakob disease. J Virol 65:6292-6295
26. Kretzschmar HA, Prusiner SB, Stowring LE, DeArmond SJ (1986) Scrapie prion proteins are synthesized in neurons. Am J Pathol 122:1-5
27. Langley B, Ratan RV (2004) Oxidative stress-induced death in the nervous system: cell cycle dependent or independent? J Neurosci Res 77:621-629
28. Mahadik SP, Scheffer RE (1996) Oxidative injury and potential use of antioxidants in schizophrenia. Prostaglandins Leukot Essent Fatty Acids 55:45-54
29. Mahadik SP, Evans D, Lal H (2001) Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 25:463-493
30. Mahadik SP, Pillai A, Joshi S, Foster A (2006) Prevention of oxidative stress-mediated neuropathology and improved clinical outcome by adjunctive use of a combination of antioxidants and omega-3 fatty acids in schizophrenia. Int Rev Psychiatry 18:119-131
31. Manson J, West JD, Thomson V, McBride P, Kaufman MH, Hope J (1992) The prion protein gene: a role in mouse embryogenesis. Development 115:117-122
32. Martins VR, Linden R, Prado MAM, Walz R, Sakamoto AC, Izquierdo I, Brentani RR (2002) Cellular prion protein: on the road for functions. FEBS Lett 512:25-28
33. Martins VR, Brentani RR (2002) The biology of the cellular prion protein. Neurochem Int 41:353-355
34. Mastrangelo P, Westaway D (2001) Biology of the prion gene complex. Biochem Cell Biol 79:613-628
35. Mead S, Stumpf MPH, Whitfield J, Beck JA, Poulter M, Campbell T, Uphill JB, Goldstein D, Alpers M, Fisher EMC, Collinge J (2003) Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics. Science 300:640-643
36. Miele G., Blanco ARA, Baybutt H, Horvat S, Manson J, Clinton M (2003) Embryonic activation and developmental expression of the murine prion protein gene. Gene Expr 11:1-12
37. Moya KL, Hässig R, Créminon C, Laffont I, Di Giamberardino L (2004) Enhanced detection and retrograde axonal transport of PrPc in peripheral nerve. J Neurochem 88:155-160
38. Moya KL, Hassig R, Breen KC, Volland H, Di Giamberardino L (2005) Axonal transport of the cellular prion protein is increased during axon regeneration. J Neurochem 92:1044-1053
39. Nakabeppu Y, Tsuchimoto D, Yamaguchi H, Sakumi K (2007) Oxidative damage in nucleic acids and Parkinson's disease. J Neurosci Res 85:919-934
40. Pammer J, Weninger W, Tschachler E (1998) Human keratinocytes express cellular prion-related protein in vitro and during inflammatory skin diseases. Am J Pathol 153:1353-1358
41. Pauly PC, Harris DA (1998) Copper stimulates endocytosis of the prion protein. J Biol Chem 273:33107-33110
42. c on the road: trafficking of the cellular prion protein. J Neurochem 88:769-781
43. Prusiner SB (1998) Prions. Proc Natl Acad Sci USA 95:13363-13383
44. Qureshi GA, Parvez SH (2007) Oxidative stress and neurodegenerative disorders. Elsevier, Amsterdam
45. Reddy RD, Yao JK (1996) Free radical pathology in schizophrenia: a review. Prostaglandins Leukot Essent Fatty Acids 55:33-43
46. Riek R, Hornemann S, Wider G, Billeter M, Glockshuber R, Wüthrich K (1996) NMR structure of the mouse prion protein domain Prp (121-231). Nature 382:180-182
47. Riek R, Hornemann S, Wider G, Glockshuber R, Wüthrich K (1997) NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231). FEBS Lett 413:282-288
48. Rivera-Milla E, Stuermer CAO, Malaga-Trillo E (2003) An evolutionary basis for scrapie disease: identification of a fish prion mRNA. Trends Genet 19:72-75
49. Roucou X, LeBlanc AC (2005) Cellular prion protein neuroprotective function: implications in prion diseases. J Mol Med 83:3-11
50. Rujescu D, Meisenzahl EM, Giegling I, Kirner A, Leinsinger G, Hegerl U, Hahn K, Moller HJ (2002) Methionine homozygosity at codon 129 in the prion protein is associated with white matter reduction and enlargement of CSF compartments in healthy volunteers and schizophrenic patients. Neuroimage 15:200-206
51. Simonic T, Duga S, Strumbo B, Asselta R, Ceciliani F, Ronchi S (2000) cDNA cloning of turtle prion protein. FEBS Lett 469:33-38
52. Singh KK (ed) (2006) Oxidative stress, disease and cancer. Imperial College, London
53. Soares JC, Gershon S (2000) Bipolar disorders. Marcel Dekker, New York
54. Steele AD, Emsley JG, Ozdinler PH, Lindquist S, Macklis JD (2006) Prion protein PrPc positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis. Proc Natl Acad Sci USA 103:3416-3421
55. Strumbo B, Ronchi S, Bolis LC, Simonic T (2001) Molecular cloning of the cDNA coding for Xenopus laevis prion protein. FEBS Lett 508:170-174
56. Tsai MT, Su YC, Chen YH, Chen CH (2001) Lack of evidence to support the association of the human prion gene with schizophrenia. Mol Psychiatry 6:74-78
57. Verghese-Nikolakaki S, Michaloudi H, Polymenidou M, Groschup MH, Papadopoulos GC, Sklaviadis T (1999): Expression of the prion protein in the rat forbrain-an immunihistochemical study. Neurosci Lett 279:9-12
58. Voigtlander T, Kloppel S, Birner P, Jarius C, Flicker H, Verghese-Nikolakaki S, Sklaviadis T, Guentchev M, Budka H (2001): Marked increase of neuronal prion protein immunoreactivity in Alzheimer's disease and human prion diaseases. Acta Neuropathol 101:417-423
59. Weis S (1991) Morphometry in the neurosciences. In: Wenger E, Dimitrov L (eds) Image processing and computer graphics: theory and applications. OCG Schriftenreihe, vol 58. Oldenburg Verlag, Oldenburg, pp 306-326
60. Weissmann C (2004): The state of the prion. Nat Rev Microbiol 2:861-871
61. Yao JK, van Kammen DP (2004) Membrane phospholipids and cytokine interaction in schizophrenia. Int Rev Neurobiol 59:297-326
62. Yao JK, Reddy RD, van Kammen DP (2001) Oxidative damage and schizophrenia: an overview of the evidence and its therapeutic implications. CNS Drugs 15:287-310
63. Zhang CC, Steele AD, Lindquist S, Lodish HF (2006) Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal. Proc Natl Acad Sci USA 103:2184-2189