Stimulatory effects of a melatonin receptor agonist, ramelteon, on BDNF in mouse cerebellar granule cells

Neuroscience Letters

Volumn 439, Issue 1, 2008, Pages 34-36

  Imbesi, Marta ^a   Uz, Tolga ^a   Dzitoyeva, Svetlana ^a   Manev, Hari ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Brain derived neurotrophic factor (BDNF); Cerebellar granule cells; Melatonin receptor; MT1; MT2; Ramelteon; Rozerem

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLOHEXIMIDE; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MESSENGER RNA; RAMELTEON;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GRANULE CELL; IN VITRO STUDY; KNOCKOUT MOUSE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSLATION REGULATION; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CEREBELLUM; CYCLOHEXIMIDE; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; INDENES; MICE; MICE, KNOCKOUT; NEURONS; PROTEIN SYNTHESIS INHIBITORS; RECEPTOR, MELATONIN, MT1; RECEPTOR, MELATONIN, MT2; RNA, MESSENGER; TIME FACTORS;

EID: 44649165647     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.04.099     Document Type: Article

References (26)

1. Al-Ghoul W.M., Herman M.D., and Dubocovich M.L. Melatonin receptor subtype expression in human cerebellum. Neuroreport 9 (1998) 4063-4068
2. Brunner P., Sozer-Topcular N., Jockers R., Ravid R., Angeloni D., Fraschini F., Eckert A., Muller-Spahn F., and Savaskan E. Pineal and cortical melatonin receptors MT1 and MT2 are decreased in Alzheimer's disease. Eur. J. Histochem. 50 (2006) 311-316
3. Dubocovich M.L., Rivera-Bermudez M.A., Gerdin M.J., and Masana M.I. Molecular pharmacology, regulation and function of mammalian melatonin receptors. Front. Biosci. 8 (2003) d1093-d1108
4. S. Dzitoyeva, M. Imbesi, T. Uz, N. Dimitrijevic, H. Manev, R. Manev, Caffeic acid attenuates the decrease of cortical BDNF transcript IV mRNA induced by swim stress in wild type but not in 5-lipoxygenase-deficient mice, J. Neural Transm. (2008) (Epub ahead of print).
5. Favaron M., Manev R.M., Rimland J.M., Candeo P., Beccaro M., and Manev H. NMDA-stimulated expression of BDNF mRNA in cultured cerebellar granule neurons. Neuroreport 4 (1993) 1171-1174
6. Greisen M.H., Altar C.A., Bolwig T.G., Whitehead R., and Wortwein G. Increased adult hippocampal brain-derived neurotrophic factor and normal levels of neurogenesis in maternal separation rats. J. Neurosci. Res. 79 (2005) 772-778
7. Jacobsen J.P., and Mork A. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain Res. 1024 (2004) 183-192
8. Jimenez-Jorge S., Guerrero J.M., Jimenez-Caliani J., Naranjo M.C., Lardone P.J., Carrillo-Vico A., Osuna C., and Molinero P. Evidence for melatonin synthesis in the rat brain during development. J. Pineal Res. 42 (2007) 240-246
9. Jin X., von Gall C., Pieschl R.L., Gribkoff V.K., Stehle J.H., Reppert S.M., and Weaver D.R. Targeted disruption of the mouse Mel (1b) melatonin receptor. Mol. Cell. Biol. 23 (2003) 1054-1060
10. Johnson M.W., Suess P.E., and Griffiths R.R. Ramelteon: a novel hypnotic lacking abuse liability and sedative effects. Arch. Gen. Psychiatry 63 (2006) 1149-1157
11. Kato K., Hirai K., Nishiyama K., Uchikawa O., Fukatsu K., Ohkawa S., Kawamata Y., Hinuma S., and Miyamoto M. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology 48 (2005) 301-310
12. Kong X., Li X., Cai Z., Yang N., Liu Y., Shu J., Pan L., and Zuo P. Melatonin regulates the viability and differentiation of rat midbrain neural stem cells. Cell Mol. Neurobiol. 28 (2008) 569-579
13. Lindholm D., Dechant G., Heisenberg C.P., and Thoenen H. Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity. Eur. J. Neurosci. 5 (1993) 1455-1464
14. Liu C., Weaver D.R., Jin X., Shearman L.P., Pieschl R.L., Gribkoff V.K., and Reppert S.M. Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19 (1997) 91-102
15. Liu Q.R., Lu L., Zhu X.G., Gong J.P., Shaham Y., and Uhl G.R. Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res. 1067 (2006) 1-12
16. Nawa H., Carnahan J., and Gall C. BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels. Eur. J. Neurosci. 7 (1995) 1527-1535
17. Niles L.P., Armstrong K.J., Castro L.M.R., Dao C.V., Sharma R., McMillan C.R., Doering L.C., and Kirkham D.L. Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers. BMC Neurosci. 5 (2004) 41
18. Radio N.M., Doctor J.S., and Witt-Enderby P.A. Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade. J. Pineal Res. 40 (2006) 332-342
19. Savaskan E., Olivieri G., Meier F., Brydon L., Jockers R., Ravid R., Wirz-Justice A., and Muller-Spahn F. Increased melatonin 1a-receptor immunoreactivity in the hippocampus of Alzheimer's disease patients. J. Pineal Res. 32 (2002) 59-62
20. Savaskan E., Ayoub M.A., Ravid R., Angeloni D., Fraschini F., Meier F., Eckert A., Muller-Spahn F., and Jockers R. Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. J. Pineal Res. 38 (2005) 10-16
21. Sutton M.A., and Schuman E.M. Local translational control in dendrites and its role in long-term synaptic plasticity. J. Neurobiol. 64 (2005) 116-131
22. Thomas L., Purvis C.C., Drew J.E., Abramovich D.R., and Williams L.M. Melatonin receptors in human fetal brain: 2-[(125)I]iodomelatonin binding and MT1 gene expression. J. Pineal Res. 33 (2002) 218-224
23. Uz T., Manev R., and Manev H. 5-Lipoxygenase is required for proliferation of immature cerebellar granule neurons in vitro. Eur. J. Pharmacol. 418 (2001) 15-22
24. Uz T., Arslan A.D., Kurtuncu M., Imbesi M., Akhisaroglu M., Dwivedi Y., Pandey G.N., and Manev H. The regional and cellular expression profile of the melatonin receptor MT1 in the central dopaminergic system. Brain. Res. Mol. Brain Res. 136 (2005) 45-53
25. Wu Y.H., Zhou J.N., Balesar R., Unmehopa U., Bao A., Jockers R., Van Heerikhuize J., and Swaab D.F. Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: colocalization of MT1 with vasopressin, oxytocin, and corticotrophin-releasing hormone. J. Comp. Neurol. 499 (2006) 897-910
26. Wu Y.H., Zhou J.N., Van Heerikhuize J., Jockers R., and Swaab D.F. Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol. Aging 28 (2007) 1239-1247