Increased melatonin 1a-receptor immunoreactivity in the hippocampus of Alzheimer's disease patients

Journal of Pineal Research

Volumn 32, Issue 1, 2002, Pages 59-62

  Savaskan, Egemen ^a   Olivieri, Gianfranco ^a   Meier, Fides ^a   Brydon, Lena ^b   Jockers, Ralf ^b   Ravid, Rivka ^c   Wirz Justice, Anna ^d   Müller Spahn, Franz ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b INSTITUT COCHIN   (France)

^c NETHERLANDS BRAIN BANK   (Netherlands)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Alzheimer's disease; Hippocampus; Immunohistochemistry; Melatonin 1a receptor (MT1)

Indexed keywords

MELATONIN RECEPTOR;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CIRCADIAN RHYTHM; CLINICAL ARTICLE; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NERVE DEGENERATION; NEUROPROTECTION; PYRAMIDAL NERVE CELL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; RETINA; STAINING;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CASE-CONTROL STUDIES; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MELATONIN; MIDDLE AGED; NEUROPROTECTIVE AGENTS; PYRAMIDAL CELLS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN;

EID: 0036161698     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079x.2002.00841.x     Document Type: Article

References (20)

1. Nitrosation of melatonin by nitric oxide and peroxynitrite
2. Neuropathological stageing of Alzheimer-related changes
3. Monozygotic twins with Alzheimer's disease treated with melatonin: Case report
4. q/11 proteins
5. Molecular pharmacology and function of melatonin receptor subtypes
6. Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia
7. Alzheimer's disease: Cell specific pathology isolates the hippocampal formation
8. The melatonin receptor in the human brain: Cloning experiments and distribution studies
9. Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles
10. The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer's disease
11. Immunohistochemical localization of EphA5 in the adult human central nervous system
12. Melatonin prevents death of neuroblastoma cells exposed to Alzheimer's amyloid peptide
13. An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease
14. Oxidative damage in the central nervous system: Protection by melatonin
15. Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and Parkinsonism
16. Hippocampal efferents reach widespread areas of cerebral cortex and amygdala in rhesus monkey
17. Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
18. Melatonin induces gamma-glutamylcysteine synthetase mediated activator protein-1 in human vascular endothelial cells
19. β-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE