5-Lipoxygenase is required for proliferation of immature cerebellar granule neurons in vitro

European Journal of Pharmacology

Volumn 418, Issue 1-2, 2001, Pages 15-22

  Uz, Tolga ^b   Manev, Radmila ^b   Manev, Hari ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NONE

Author keywords

5 Lipoxygenase; AA 861; Antisense; L 655,238; MK 886; Neurogenesis

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; BETA TUBULIN; BROXURIDINE; DOCEBENONE; LIPOXYGENASE INHIBITOR; THYMIDINE;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CELL PROLIFERATION; CEREBELLUM; GENE EXPRESSION; GRANULE CELL; INFLAMMATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CEREBELLUM; DNA; IMMUNOHISTOCHEMISTRY; NEURONS; OLIGONUCLEOTIDES, ANTISENSE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS;

EID: 0035917638     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00924-4     Document Type: Article

References (40)

1. Peripheral infusion of IGF-I selectively induces neurogenesis in the adult rat hippocampus
2. 5-Lipoxygenase inhibitors reduce PC-3 cell proliferation and initiate non-necrotic cell death
3. Do lipoxygenases modulate normal or aberrant lympho-hematopoiesis?
4. Isolation and characterization of a cDNA clone encoding rat 5-lipoxygenase
5. Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat
6. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
7. Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain
8. 5-Lipoxygenase deficiency-induced cell growth arrest and apoptosis in mouse mast cells
9. The 5-lipoxygenase-activating protein (FLAP) inhibitor MK 886, induces apoptosis independently of FLAP
10. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells
11. Opiates inhibit neurogenesis in the adult rat hipppocampus
12. Neurogenesis in the adult human hippocampus
13. GABA induces proliferation of immature cerebellar granule cells grown in vitro
14. Arachidonic acid stimulates prostate cancer cell growth: Critical role of 5-lipoxygenase
15. Neurogenesis in the neocortex of adult primates
16. Genetic factors determine the contribution of leukotrienes to acute inflammatory responses
17. Opioids intrinsically inhibit the genesis of mouse cerebellar granule neuron precursors in vitro: Differential impact of and mgr; and delta receptor activation on proliferation and neurite elongation
18. Chronic fluoxetine treatment increases hippocampal neurogenesis in rats: A novel theory of depression
19. Transforming growth factor-β2 both stimulates and inhibits neurogenesis of rat cerebellar granule cells in culture
20. 5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins
21. Inhibition of mitogen-activated protein kinase blocks activation and redistribution of 5-lipoxygenase in HL-60 cells
22. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
23. Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells
24. Chronic antidepressant administration increases granule cell genesis in the hippocampus of the adult male rat
25. Primary cultures of rat cerebellar granule cells as a model to study neuronal 5-lipoxygenase and FLAP gene expression
26. Delayed increase of calcium influx elicited by glutamate: Role in neuronal death
27. Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells
28. Putative role of neuronal 5-lipoxygenase in an aging brain
29. Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro
30. Leukotriene C4 synthesis deficiency: A member of a probably underdiagnosed new group of neurometabolic diseases
31. Leukotriene C4-synthesis deficiency: A new inborn error of metabolism linked to a fatal developmental syndrome
32. Zileuton
33. Lipoxygenase inhibition in prostate cancer
34. 12-Lipoxygenase mRNA expression by cultured neurons
35. Anti-inflammatory properties of mizolastine after oral administration on arachidonic acid-induced cutaneous reaction in the rat
36. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus
37. Increased hippocampal 5-lipoxygenase mRNA content in melatonin-deficient, pinealectomized rats
38. Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain
39. Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
40. Cerebellar granule cells elaborate neurites before mitosis