Transient silencing of Plasmodium falciparum Tudor Staphylococcal Nuclease suggests an essential role for the protein

Biochemical and Biophysical Research Communications

Volumn 372, Issue 2, 2008, Pages 373-378

  Sunil, Sujatha ^a   Hossain, Manzar J ^a   Ramasamy, Gowthaman ^a   Malhotra, Pawan ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

Malaria; Plasmodium; RNAi; Tudor Staphylococcal Nuclease

Indexed keywords

3',5' DEOXYTHYMIDINE BIPHOSPHATE; MESSENGER RNA; NUCLEASE; PHOSPHATE; RNA; SMALL INTERFERING RNA;

ARTICLE; BACTERIAL GROWTH; GENE SEQUENCE; GENE SILENCING; GIEMSA STAIN; MORPHOLOGY; NONHUMAN; PARASITE CULTIVATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA INTERFERENCE; STAPHYLOCOCCUS; TROPHOZOITE;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; ENZYME INHIBITORS; HUMANS; MICROCOCCAL NUCLEASE; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; THYMINE NUCLEOTIDES;

PLASMODIUM FALCIPARUM; VERTEBRATA;

EID: 44649147680     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.05.033     Document Type: Article

References (29)

1. Hemingway J., and Craig A. New ways to control malaria. Science 303 (2007) 1984-1985
2. Sutherland C. A challenge for the development of malaria vaccines: polymorphic target antigens. PLoS Med. 4 (2007) 413-414
3. Ridley R.G. Medical need, scientific opportunity and the drive for antimalarial drugs. Nature 415 (2002) 686-693
4. Hossain M.J., Korde R., Singh S., Mohmmed A., Dasaradhi P.V.N., Chauhan V.S., and Malhotra P. Tudor domain proteins in protozoan parasites and characterization of Plasmodium falciparum tudor-Staphylococcal Nuclease. Int. J. Parasitol. 38 (2008) 513-526
5. Pointing C.P. P100, a transcriptional co-activator, is a human homologue of Staphylococcal Nuclease. Protein Sci. 6 (1997) 459-463
6. Yang J., Aittomski S., Pesu M., Carter K., Sarrinsen J., Kalkkinen N., Kieff E., and Silvennoinen O. Identification of p100 as a coactivator for STAT6 that bridges STAT6 and RNA polymerase II. EMBO J. 21 (2002) 4950-4958
7. Tong X., Drapkin R.Y., Moaialos G., and Kieff E. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular co-activator that interacts with TFIIE. Mol. Cell. Biol. 15 (1995) 735-744
8. Porta A., Colonna-Romano S., Callibaut I., Franco A., Marzullo L., Kobayashi G.S., and Maresca B. A homologue of the human 100 kDa protein (p100) is differentially expressed by Histoplasma capsulatum during infection of murine macrophages. Biochem. Biophys. Res. Commun. 254 (1999) 605-613
9. Schroder H.C., Rotman M., Bachmann M., Muller W.E., McDonald A.R., and Aguter P.S. Proteins from rat liver cytosol which stimulates mRNA transport. Eur. J. Biochem. 59 (1986) 51-59
10. Abe S., Sakai M., Yagi K., Hagino T., Ochi K., Shibata K., and Davies E. A Tudor protein with multiple SNc domains from pea seedlings: cellular localization, partial characterization, sequence analysis and phylogenetic relationships. J. Exp. Bot. 54 (2003) 971-983
11. C. Wang, H. Washida, A.J. Crofts, S. Hamada, T. Katsube-Tanaka, D. Kim, S.B. Choi, M. Modi, S. Singh, T.W. Okita, The cytoplasmic-localized, cytoskeletal-associated RNA binding protein OsTudor-SN: evidence for an essential role in storage protein RNA transport and localization, Plant J. (2008), in press.
12. Caudy A.A., Ketting R.F., Hammond S.M., Denli A.M., Bathoorn A.M.P., Tops B.B.J., Silva M.J., myers M.M., Hannon G.J., and Plasterk R.H.A. A micrococcal nuclease homologue in RNAi effector complexes. Nature 425 (2003) 411-414
13. Scadden A.D.J. The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage. Nat. Struc. Mol. Biol. 6 (2005) 489-496
14. McRobert L., and McConkey G. RNA interference (RNAi) inhibits growth of Plasmodium falciparum. Mol. Biochem. Parasitol. 119 (2002) 273-278
15. Malhotra P., Dasaradhi P.V.N., Kumar A., Mohmmed A., Agrawal N., Bhatnagar R.K., and Chauhan V.S. Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum. Mol. Microbiol. 45 (2002) 1245-1254
16. Gissot M., Briquet S., Refour P., Boschet C., and Vaquero C. PfMyb1, a Plasmodium falciparum transcription factor, is required for intra-erythrocytic growth and controls key genes for cell cycle regulation. J. Mol. Biol. 346 (2005) 29-42
17. Ullu U., Tschudi C., and Chakraborthy T. RNA interference in protozoan parasites. Cell Microbiol. 6 (2004) 509-514
18. Pradhan A., and Tuteja R. Bipolar, dual Plasmodium falciparum helicase 45 expressed in the erythrocytic development cycle is required for parasite growth. J. Mol. Biol. 273 (2007) 268-281
19. Basagoudanavar S.H., Feng X., Krishnegowda G., Muthusamy A., and Channe Gowde D. Plasmodium falciparum GPI manosyltransferase-III has a novel signature sequence and is functional. Biochem. Biophys. Res. Commun. 364 (2007) 748-754
20. Schwarz D.S., Hutvagner G., Du T., Xu Z., Aronin N., and Zamore P.D. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115 (2003) 199-206
21. Khvorova A., Reynolds A., and Jayasena S.D. Functional siRNAs and miRNAs exhibit strand Bias. Cell 115 (2003) 209-216
22. 2+-dependent endonuclease. Curr. Biol. 14 (2004) 787-791
23. Trager W., and Jenson J.B. Human malaria parasite in continuous culture. Science 193 (1976) 673-675
24. Blair P.L., Witney A., Haynes J.D., Moch J.K., Carucci D.J., and Adams J.H. Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT-PCR. Nucleic Acid Res. 10 (2002) 2224-2231
25. Gardiner D.L., Skinner-Adams T.S., Spielmann T., and Trenholme K.R. Malaria transfection and transfection vectors. Trends Parasitol. 19 (2003) 381-384
26. Janse C.L., Franke-Fayard B., Mair G.R., Ramesar J., Thiel C., Engelmann S., Matuschewski K., van Gemart G.J., Sauierwein R.W., and Waters A.P. High efficiency transfection of Plasmodium berghei facilitates novel selection procedures. Mol. Biochem. Parasitol. 145 (2006) 60-70
27. Pukku K., Yang J., and Silvennoinen O. Tudor and nuclease like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5. Mol. Endocrinol. 17 (2003) 1805-1814
28. Dash A.B., Oriko F.C., and Ness S.A. The EVES motif mediates both intermolecular and intramolecular regulation of c-Myb activity. Genes Dev. 10 (1996) 1858-1869
29. Leverson J.D., Koskinen P.J., Orrico F.C., Rainio E.M., Jalkanen K.J., Dash A.B., Elsenman R.N., and Ness S.A. Pim-1 kinase and p100 cooperate to enhance c-Myb activity. Mol. Cell 2 (1998) 417-425