A highly sensitive and reproducible HCV RNA hybridization method valuable for antiviral drug discovery

Journal of Virological Methods

Volumn 151, Issue 1, 2008, Pages 154-157

  Zhao, Yongsen ^a   Sanchez, Amy ^a   Nie, Xingtie ^a   Liu, Dongmei ^a   Hou, Xiaohong ^a   Fabrycki, Joanne ^a   Phadke, Avinash ^a   Deshpande, Milind ^a   Huang, Mingjun ^a   Yang, Wengang ^a  

^a Achillion Pharmaceuticals   (United States)

Author keywords

Antiviral drug discovery; HCV; Hybridization; Replicon

Indexed keywords

2' C METHYLADENOSINE; 5 CYCLOPROPYL 2 (4 FLUOROPHENYL) 6 [N (2 HYDROXYETHYL)METHANESULFONAMIDO] N METHYLBENZOFURAN 3 CARBOXAMIDE; ALPHA2B INTERFERON; ANTIVIRUS AGENT; LAMIVUDINE; LUCIFERASE; TELAPREVIR; VIRUS RNA;

ARTICLE; ASSAY; CELL DENSITY; CELL LYSATE; CONTROLLED STUDY; CROSS LINKING; DOSE RESPONSE; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPLICON; RNA HYBRIDIZATION; RNA PURIFICATION; ULTRAVIOLET RADIATION;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPACIVIRUS; HUMANS; LIVER; MICROBIAL SENSITIVITY TESTS; NUCLEIC ACID HYBRIDIZATION; REPLICON; REPRODUCIBILITY OF RESULTS; RNA, VIRAL; SENSITIVITY AND SPECIFICITY; VIRUS REPLICATION;

HEPATITIS B VIRUS; HEPATITIS C VIRUS;

EID: 44649141240     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2008.03.027     Document Type: Article

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