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Volumn 72, Issue 3, 2008, Pages 278-286

Neurohormonal and metabolic effects of medetomidine compared with xylazine in healthy cats

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ALPHA 2 ADRENERGIC RECEPTOR; CATECHOLAMINE; FATTY ACID; GLUCAGON; GLUCOSE; HYDROCORTISONE; INSULIN; MEDETOMIDINE; NEUROHORMONE; NORADRENALIN; SODIUM CHLORIDE; XYLAZINE;

EID: 44649123676     PISSN: 08309000     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (40)
  • 1
    • 0033071206 scopus 로고    scopus 로고
    • Pros and cons of using alpha-2 agonists in small animal anesthesia practice
    • Greene SA. Pros and cons of using alpha-2 agonists in small animal anesthesia practice. Clin Tech Small Anim Pract 1999;14: 10-14.
    • (1999) Clin Tech Small Anim Pract , vol.14 , pp. 10-14
    • Greene, S.A.1
  • 2
    • 0026729168 scopus 로고
    • Alpha adrenoceptor subtypes involved in the emetic action in dogs
    • Hikasa Y, Ogasawara S, Takase K. Alpha adrenoceptor subtypes involved in the emetic action in dogs. J Pharmacol Exp Ther 1992;261:746-754.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 746-754
    • Hikasa, Y.1    Ogasawara, S.2    Takase, K.3
  • 3
    • 0025648196 scopus 로고
    • Synergistic effect of growth hormone-releasing hormone (GHRH) and clonidine in stimulating GH release in young and old dogs
    • Arce V, Cella SG, Loche S, Ghigo E, Devesa J, Müller EE. Synergistic effect of growth hormone-releasing hormone (GHRH) and clonidine in stimulating GH release in young and old dogs. Brain Res 1990;537:359-362.
    • (1990) Brain Res , vol.537 , pp. 359-362
    • Arce, V.1    Cella, S.G.2    Loche, S.3    Ghigo, E.4    Devesa, J.5    Müller, E.E.6
  • 4
    • 0024345047 scopus 로고
    • Pharmacological profiles of medetomidine and its antagonist, atipamezole
    • Virtanen R. Pharmacological profiles of medetomidine and its antagonist, atipamezole. Acta Vet Scand Suppl 1989;85: 29-37.
    • (1989) Acta Vet Scand Suppl , vol.85 , pp. 29-37
    • Virtanen, R.1
  • 5
    • 17544380177 scopus 로고    scopus 로고
    • Influence of medetomidine on stress-related neurohormonal and metabolic effects caused by butorphanol, fentanyl, and ketamine administration in dogs
    • Ambrisko TD, Hikasa Y, Sato K. Influence of medetomidine on stress-related neurohormonal and metabolic effects caused by butorphanol, fentanyl, and ketamine administration in dogs. Am J Vet Res 2005;66:406-412.
    • (2005) Am J Vet Res , vol.66 , pp. 406-412
    • Ambrisko, T.D.1    Hikasa, Y.2    Sato, K.3
  • 6
    • 0036182557 scopus 로고    scopus 로고
    • Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs
    • Ambrisko TD, Hikasa Y. Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs. Can J Vet Res 2002;66:42-49.
    • (2002) Can J Vet Res , vol.66 , pp. 42-49
    • Ambrisko, T.D.1    Hikasa, Y.2
  • 8
    • 0002904351 scopus 로고
    • The cat: Normal hematology with comments on response to disease
    • Jain NC, ed, 4th ed. Philadelphia: Lea & Febiger
    • Jain NC. The cat: normal hematology with comments on response to disease. In: Jain NC, ed. Schalm's Veterinary Hematology. 4th ed. Philadelphia: Lea & Febiger, 1986:126-139
    • (1986) Schalm's Veterinary Hematology , pp. 126-139
    • Jain, N.C.1
  • 9
    • 0021981802 scopus 로고
    • Methodological considerations in the determination of plasma catecholamines by high-performance liquid chromatography with electrochemical detection
    • Bouloux P, Perrett D, Besser GM. Methodological considerations in the determination of plasma catecholamines by high-performance liquid chromatography with electrochemical detection. Ann Clin Biochem 1985;22:194-203.
    • (1985) Ann Clin Biochem , vol.22 , pp. 194-203
    • Bouloux, P.1    Perrett, D.2    Besser, G.M.3
  • 10
    • 0019473437 scopus 로고
    • Effect of xylazine on plasma glucose, glucagon and insulin concentrations in sheep
    • Brockman RP. Effect of xylazine on plasma glucose, glucagon and insulin concentrations in sheep. Res Vet Sci 1981;30:383-384.
    • (1981) Res Vet Sci , vol.30 , pp. 383-384
    • Brockman, R.P.1
  • 11
    • 0034485907 scopus 로고    scopus 로고
    • The effects of medetomidine and its reversal with atipamezole on plasma glucose, cortisol and noradrenaline in cattle and sheep
    • Ranheim B, Horsberg TE, Søli NE, Ryeng KA, Arnemo JM. The effects of medetomidine and its reversal with atipamezole on plasma glucose, cortisol and noradrenaline in cattle and sheep. J Vet Pharmacol Ther 2000;23:379-387.
    • (2000) J Vet Pharmacol Ther , vol.23 , pp. 379-387
    • Ranheim, B.1    Horsberg, T.E.2    Søli, N.E.3    Ryeng, K.A.4    Arnemo, J.M.5
  • 12
    • 0036512526 scopus 로고    scopus 로고
    • Acute stress hyperglycemia in cats is associated with struggling and increased concentrations of lactate and norepinephrine
    • Rand JS, Kinnaird E, Baglioni A, Blackshaw J, Priest J. Acute stress hyperglycemia in cats is associated with struggling and increased concentrations of lactate and norepinephrine. J Vet Intern Med 2002;16:123-132.
    • (2002) J Vet Intern Med , vol.16 , pp. 123-132
    • Rand, J.S.1    Kinnaird, E.2    Baglioni, A.3    Blackshaw, J.4    Priest, J.5
  • 13
    • 0022399060 scopus 로고
    • Effects of alpha-adrenoceptor agonists and antagonists on insulin secreting cells and pancreatic blood vessels: Comparative study
    • Hillaire-Buys D, Gross K, Blayac JP, Ribes G, Loubatières-Mariani MM. Effects of alpha-adrenoceptor agonists and antagonists on insulin secreting cells and pancreatic blood vessels: comparative study. Eur J Pharmacol 1985;117:253-257.
    • (1985) Eur J Pharmacol , vol.117 , pp. 253-257
    • Hillaire-Buys, D.1    Gross, K.2    Blayac, J.P.3    Ribes, G.4    Loubatières-Mariani, M.M.5
  • 14
    • 0020032686 scopus 로고
    • Alpha 2-adrenergic inhibition of insulin secretion via interference with cyclic AMP generation in rat pancreatic islets
    • Yamazaki S, Katada T, Ui M. Alpha 2-adrenergic inhibition of insulin secretion via interference with cyclic AMP generation in rat pancreatic islets. Mol Pharmacol 1982;21:648-653.
    • (1982) Mol Pharmacol , vol.21 , pp. 648-653
    • Yamazaki, S.1    Katada, T.2    Ui, M.3
  • 15
    • 0019225585 scopus 로고
    • Effects of clonidine on glucose production and insulin secretion of cattle
    • Gorewit RC. Effects of clonidine on glucose production and insulin secretion of cattle. Am J Vet Res 1980;41:1769-1772.
    • (1980) Am J Vet Res , vol.41 , pp. 1769-1772
    • Gorewit, R.C.1
  • 16
    • 0019466005 scopus 로고
    • Xylazine-induced hyperglycemia in cattle: A possible involvement of alpha 2-adrenergic receptors regulating insulin release
    • Hsu WH, Hummel SK. Xylazine-induced hyperglycemia in cattle: a possible involvement of alpha 2-adrenergic receptors regulating insulin release. Endocrinology 1981;109:825-829.
    • (1981) Endocrinology , vol.109 , pp. 825-829
    • Hsu, W.H.1    Hummel, S.K.2
  • 17
    • 0021350526 scopus 로고
    • Mechanisms involved in the hyperglycemic response induced by clonidine and other alpha-2 adrenoceptor agonists
    • DiTullio NW, Cieslinski L, Matthews WD, Storer B. Mechanisms involved in the hyperglycemic response induced by clonidine and other alpha-2 adrenoceptor agonists. J Pharmacol Exp Ther 1984;228:168-173.
    • (1984) J Pharmacol Exp Ther , vol.228 , pp. 168-173
    • DiTullio, N.W.1    Cieslinski, L.2    Matthews, W.D.3    Storer, B.4
  • 18
    • 0023848761 scopus 로고
    • Central versus peripheral effect of clonidine on hepatic venous plasma glucose concentrations in fasted rats
    • Gotoh M, Iguchi A, Sakamoto N. Central versus peripheral effect of clonidine on hepatic venous plasma glucose concentrations in fasted rats. Diabetes 1988;37:44-49.
    • (1988) Diabetes , vol.37 , pp. 44-49
    • Gotoh, M.1    Iguchi, A.2    Sakamoto, N.3
  • 19
    • 0021124875 scopus 로고
    • Effect of xylazine hydrochloride upon plasma glucose and serum insulin concentrations in adult pointer dogs
    • Benson GJ, Thurmon JC, Neff CA. Effect of xylazine hydrochloride upon plasma glucose and serum insulin concentrations in adult pointer dogs J Am Anim Hosp Assoc 1984;20:791-794.
    • (1984) J Am Anim Hosp Assoc , vol.20 , pp. 791-794
    • Benson, G.J.1    Thurmon, J.C.2    Neff, C.A.3
  • 20
    • 0030817781 scopus 로고    scopus 로고
    • Effects of medetomidine on serum insulin and plasma glucose concentrations in clinically normal dogs
    • Burton SA, Lemke KA, Ihle SL, Mackenzie AL. Effects of medetomidine on serum insulin and plasma glucose concentrations in clinically normal dogs. Am J Vet Res 1997;58:1440-1442.
    • (1997) Am J Vet Res , vol.58 , pp. 1440-1442
    • Burton, S.A.1    Lemke, K.A.2    Ihle, S.L.3    Mackenzie, A.L.4
  • 21
    • 0033209660 scopus 로고    scopus 로고
    • Comparison of the activities of enzymes related to glycolysis and gluconeogenesis in the liver of dogs and cats
    • Washizu T, Tanaka A, Sako T, Washizu M, Arai T. Comparison of the activities of enzymes related to glycolysis and gluconeogenesis in the liver of dogs and cats. Res Vet Sci 1999;67:205-206.
    • (1999) Res Vet Sci , vol.67 , pp. 205-206
    • Washizu, T.1    Tanaka, A.2    Sako, T.3    Washizu, M.4    Arai, T.5
  • 22
    • 0026781242 scopus 로고
    • Alpha- and beta-adrenoceptor cross-talk in the regulation of glycogenolysis in dog and guinea-pig liver
    • Maroto R, Calvo S, Sancho C, Esquerro E. Alpha- and beta-adrenoceptor cross-talk in the regulation of glycogenolysis in dog and guinea-pig liver. Arch Int Pharmacodyn Ther 1992; 317:35-46.
    • (1992) Arch Int Pharmacodyn Ther , vol.317 , pp. 35-46
    • Maroto, R.1    Calvo, S.2    Sancho, C.3    Esquerro, E.4
  • 23
    • 0030882284 scopus 로고    scopus 로고
    • Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells
    • Hirose H, Seto Y, Maruyama H, Dan K, Nakamura K, Saruta T. Effects of alpha 2-adrenergic agonism, imidazolines, and G-protein on insulin secretion in beta cells. Metabolism 1997;46:17146-71149.
    • (1997) Metabolism , vol.46 , pp. 17146-71149
    • Hirose, H.1    Seto, Y.2    Maruyama, H.3    Dan, K.4    Nakamura, K.5    Saruta, T.6
  • 25
    • 0023125251 scopus 로고
    • Alpha 2-adrenoceptor agonists stimulate growth hormone secretion but have no acute effects on plasma cortisol under basal conditions
    • Grossman A, Weerasuriya K, Al-Damluji S, Turner P, Besser GM. Alpha 2-adrenoceptor agonists stimulate growth hormone secretion but have no acute effects on plasma cortisol under basal conditions. Horm Res 1987;25:65-71.
    • (1987) Horm Res , vol.25 , pp. 65-71
    • Grossman, A.1    Weerasuriya, K.2    Al-Damluji, S.3    Turner, P.4    Besser, G.M.5
  • 26
    • 0033629726 scopus 로고    scopus 로고
    • Perioperative stress response in the dog: Effect of pre-emptive administration of medetomidine
    • Benson GJ, Grubb TL, Neff-Davis C, et al. Perioperative stress response in the dog: effect of pre-emptive administration of medetomidine. Vet Surg 2000;29:85-91.
    • (2000) Vet Surg , vol.29 , pp. 85-91
    • Benson, G.J.1    Grubb, T.L.2    Neff-Davis, C.3
  • 27
    • 0027119676 scopus 로고
    • Comparison of serum cortisol concentration before and after intradermal testing in sedated and nonsedated dogs
    • Frank LA, Kunkle GA, Beale KM. Comparison of serum cortisol concentration before and after intradermal testing in sedated and nonsedated dogs. J Am Vet Med Assoc 1992;200:507-510.
    • (1992) J Am Vet Med Assoc , vol.200 , pp. 507-510
    • Frank, L.A.1    Kunkle, G.A.2    Beale, K.M.3
  • 28
    • 0032478680 scopus 로고    scopus 로고
    • Effects of atipamezole, detomidine and medetomidine on release of steroid hormones by porcine adrenocortical cells in vitro
    • Jager LP, De Graaf GJ, Widjaja-Greefkes HC. Effects of atipamezole, detomidine and medetomidine on release of steroid hormones by porcine adrenocortical cells in vitro. Eur J Pharmacol 1998;346:71-76.
    • (1998) Eur J Pharmacol , vol.346 , pp. 71-76
    • Jager, L.P.1    De Graaf, G.J.2    Widjaja-Greefkes, H.C.3
  • 29
    • 0025813418 scopus 로고
    • Effects of dexmedetomidine, a novel imidazole sedative-anesthetic agent, on adrenal steroidogenesis: In vivo and in vitro studies
    • Maze M, Virtanen R, Daunt D, Banks SJ, Stover EP, Feldman D. Effects of dexmedetomidine, a novel imidazole sedative-anesthetic agent, on adrenal steroidogenesis: in vivo and in vitro studies. Anesth Analg 1991;73:204-208.
    • (1991) Anesth Analg , vol.73 , pp. 204-208
    • Maze, M.1    Virtanen, R.2    Daunt, D.3    Banks, S.J.4    Stover, E.P.5    Feldman, D.6
  • 31
    • 0031668941 scopus 로고    scopus 로고
    • Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole: A pharmacodynamic and kinetic study in healthy volunteers
    • Scheinin H, Aantaa R, Anttila M, Hakola P, Helminen A, Karhuvaara S. Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole: a pharmacodynamic and kinetic study in healthy volunteers. Anesthesiology 1998;89:574-584.
    • (1998) Anesthesiology , vol.89 , pp. 574-584
    • Scheinin, H.1    Aantaa, R.2    Anttila, M.3    Hakola, P.4    Helminen, A.5    Karhuvaara, S.6
  • 32
    • 0025761216 scopus 로고
    • Detomidine reduces the plasma catecholamine, but not cortisol concentrations in horses
    • Raekallio M, Vainio O, Scheinin M. Detomidine reduces the plasma catecholamine, but not cortisol concentrations in horses. Zentralbl Veterinarmed A 1991;38:153-156.
    • (1991) Zentralbl Veterinarmed A , vol.38 , pp. 153-156
    • Raekallio, M.1    Vainio, O.2    Scheinin, M.3
  • 33
    • 0030639264 scopus 로고    scopus 로고
    • The effect of detomidine and its antagonism with tolazoline on stress-related hormones, metabolites, physiologic responses, and behavior in awake ponies
    • Carroll GL, Matthews NS, Hartsfield SM, Slater MR, Champney TH, Erickson SW. The effect of detomidine and its antagonism with tolazoline on stress-related hormones, metabolites, physiologic responses, and behavior in awake ponies. Vet Surg 1997;26:69-77.
    • (1997) Vet Surg , vol.26 , pp. 69-77
    • Carroll, G.L.1    Matthews, N.S.2    Hartsfield, S.M.3    Slater, M.R.4    Champney, T.H.5    Erickson, S.W.6
  • 34
    • 20844462386 scopus 로고    scopus 로고
    • Effect of medetomidine and its antagonism with atipamezole on stress-related hormones, metabolites, physiologic responses, sedation, and mechanical threshold in goats
    • Carroll GL, Hartsfield SM, Champney TH, Geller SC, Martinez EA, Haley EL. Effect of medetomidine and its antagonism with atipamezole on stress-related hormones, metabolites, physiologic responses, sedation, and mechanical threshold in goats. Vet Anaesth Analg 2005;32:147-157.
    • (2005) Vet Anaesth Analg , vol.32 , pp. 147-157
    • Carroll, G.L.1    Hartsfield, S.M.2    Champney, T.H.3    Geller, S.C.4    Martinez, E.A.5    Haley, E.L.6
  • 35
    • 0031016238 scopus 로고    scopus 로고
    • Modulation of catecholamine release by alpha 2-adrenoceptors and I1-imidazoline receptors in rat brain
    • Meana JJ, Herrera-Marschitz M, Goiny M, Silveira R. Modulation of catecholamine release by alpha 2-adrenoceptors and I1-imidazoline receptors in rat brain. Brain Res 1997;744: 216-226.
    • (1997) Brain Res , vol.744 , pp. 216-226
    • Meana, J.J.1    Herrera-Marschitz, M.2    Goiny, M.3    Silveira, R.4
  • 36
    • 0023802852 scopus 로고
    • Analysis of the baroreflex activation of the sympathetic system in waking cats induced by urapidil and sodium nitroprusside]
    • Medvedev OS, Kuz'min AI, Iashina LP, Rozin BD, Maǐorov DN. [Analysis of the baroreflex activation of the sympathetic system in waking cats induced by urapidil and sodium nitroprusside]. Farmakol Toksikol 1988;51:53-56.
    • (1988) Farmakol Toksikol , vol.51 , pp. 53-56
    • Medvedev, O.S.1    Kuz'min, A.I.2    Iashina, L.P.3    Rozin, B.D.4    Maǐorov, D.N.5
  • 38
    • 0032217164 scopus 로고    scopus 로고
    • The alpha2-adrenoceptor agonists xylazine and guanfacine exert different central nervous system, but comparable peripheral effects in calves
    • Scholtysik G, Regli F, Bruckmaier RM, Blum JW. The alpha2-adrenoceptor agonists xylazine and guanfacine exert different central nervous system, but comparable peripheral effects in calves. J Vet Pharmacol Ther 1998;21:477-484.
    • (1998) J Vet Pharmacol Ther , vol.21 , pp. 477-484
    • Scholtysik, G.1    Regli, F.2    Bruckmaier, R.M.3    Blum, J.W.4
  • 39
    • 0024261888 scopus 로고
    • Mechanism of the lipid-mobilizing effect of alpha-2 adrenergic antagonists in the dog
    • Taouis M, Berlan M, Montastruc P, Lafontan M. Mechanism of the lipid-mobilizing effect of alpha-2 adrenergic antagonists in the dog. J Pharmacol Exp Ther 1988;247:1172-1180.
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 1172-1180
    • Taouis, M.1    Berlan, M.2    Montastruc, P.3    Lafontan, M.4
  • 40
    • 0030071648 scopus 로고    scopus 로고
    • Alpha 2A-adrenergic regulation of cyclic AMP accumulation and lipolysis in human omental and subcutaneous adipocytes
    • Vikman HL, Savola JM, Raasmaja A, Ohisalo JJ. Alpha 2A-adrenergic regulation of cyclic AMP accumulation and lipolysis in human omental and subcutaneous adipocytes. Int J Obes Relat Metab Disord 1996;20:185-189.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 185-189
    • Vikman, H.L.1    Savola, J.M.2    Raasmaja, A.3    Ohisalo, J.J.4


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