Modulation of catecholamine release by α2-adrenoceptors and I1-imidazoline receptors in rat brain

Brain Research

Volumn 744, Issue 2, 1997, Pages 216-226

  Meana, J Javier ^a,b   Herrera Marschitz, Mario ^a   Goiny, Michel ^a   Silveira, Rodolfo ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

2 adrenoceptor; cloni dine; dopamine; imidazoline receptor; microdialysis; norepinephrine; rat

Indexed keywords

2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; ALPHA 2 ADRENERGIC RECEPTOR; CIRAZOLINE; CLONIDINE; DESIPRAMINE; DIHYDROXYPHENYLACETIC ACID; DOPAMINE; GUANABENZ; HOMOVANILLIC ACID; IDAZOXAN; IMIDAZOLINE RECEPTOR; MOXONIDINE; NORADRENALIN;

ANIMAL EXPERIMENT; ARTICLE; CATECHOLAMINE RELEASE; CINGULATE GYRUS; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; BRAIN; CATECHOLAMINES; CLONIDINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DRUG;

EID: 0031016238     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01080-3     Document Type: Article

References (74)

1. Abercrombie, E.D., Keller, R.W. and Zigmond, M.J., Characterization of hippocampal norepinephrine release as measured by micro-dialysis perfusion: pharmacological and behavioral studies, Neuroscience, 27 (1988) 897-904.
2. 2-adrenoceptor binding and function after irreversible inactivation by N-ethoxycarbony1-2-ethoxy-1,2-dihydroquinoline (EEDQ), Eur. J. Pharmacol., 116 (1985) 175-178.
3. Andén, N.E. and Grabowska, M., Pharmacological evidence for a stimulation of dopamine neurons by noradrenaline neurons in the brain, Eur. J. Pharmacol., 39 (1976) 275-282.
4. Andén, N.E. and Grabowska-Andén, M., Formation of deaminated metabolites of dopamine in noradrenaline neurons, Naunyn-Schmiedeberg's Arch. Pharmacol., 324 (1983) 1-6.
5. Aston-Jones, G., Ennis, M., Pieribone, V.A., Nickell, W.T. and Shipley, M.T., The brain nucleus locus coeruleus: restricted afferent control of a broad efferent network. Science, 234 (1986) 734-737.
6. Atlas, D., Clonidine-displacing substance (CDS) and its putative imidazoline receptor, Biochem. Pharmacol., 41 (1991) 1541-1549.
7. 2-adrenoceptors in the rat brain, Mol. Pharmacol., 42 (1992) 846-855.
8. Bousquet, P., Feldman, J. and Schwartz, J., Central cardiovascular effects of alpha adrenergic drugs. Differences between catecholamines and imidazolines, J. Pharmacol. Exp. Ther., 230 (1984) 232-236.
9. Bousquet, P., Feldman, J. and Atlas, D., An endogenous non catecholamine clonidine antagonist increases mean arterial blood pressure, Eur. J. Pharmacol., 124 (1986) 167-170.
10. Bricca, G., Dontenwill, M., Molines, A., Feldman, J., Belcourt, A. and Bousquet, P., The imidazoline preferring receptor: binding studies in bovine, rat and human brainstem, Eur. J. Pharmacol., 162 (1989) 1-9.
11. 3H]clonidine to identify imidazoline receptors in the rabbit brainstem, Br. J. Pharmacol., 110 (1993) 1537-1543.
12. 2-adrenergic receptors in the antihypertensive responses evoked by central administration of clonidine analogs in conscious spontaneously hypertensive rats, J. Pharmacol. Exp. Ther., 273 (1995) 1162-1171.
13. Carboni, E., Tanda, G.L., Frau, R. and Di Chiara, G., Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: Evidence that dopamine is taken up in vivo by noradrenergic terminals, J. Neurochem., 55 (1990) 1067-1070.
14. Cedarbaum, J.M. and Aghajanian, G.K., Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane, Brain Res., 112 (1976) 413-419.
15. 2 -adrenoceptor agonists, medetomidine, clonidine and UK 14,304 on extraneuronal levels of noradrenaline in the rat frontal cortex: evaluation using in vivo microdialysis and synaptosomal uptake studies, Br. J. Pharmacol., 114 (1995) 1717-1723.
16. 2 -adrenoceptors in the human central nervous system, Neuroscience, 59 (1994) 589-598.
17. Ennis, M. and Aston-Jones, G., Activation of locus coeruleus from nucleus paragigantocellularis: a new excitatory amino acid pathway in brain, J. Neurosci., 8 (1988) 3644-3657.
18. 2 -adrenoceptors in the ventrolateral medulla, Eur. J. Pharmacol., 134 (1987) 1-13.
19. Ernsberger, P., Meeley, M.P. and Reis, D.J., An endogenous substance with clonidine-like properties: selective binding to imidazole sites in the ventrolateral medulla, Brain Res., 441 (1988) 309-318.
20. 1-imidazoline receptors, J. Cardiovasc. Pharmacol., 20 (Suppl. 4) (1992) S1-S10.
21. 1 -imidazoline sites, J. Pharmacol. Exp. Ther., 264 (1993) 172-182.
22. Feldman, J., Tibiriça, E., Bricca, G., Dontenwill, M., Belcourt, A. and Bousquet, P., Evidence for the involvement of imidazoline receptors in the central hypotensive effect of rilmenidine in the rabbit, Br. J. Pharmacol., 100 (1990) 600-604.
23. Gomez, R.E., Ernsberger, P., Feinland, G. and Reis, D.J., Rilmenidine lowers arterial pressure via imidazole receptors in brainstem C1 area, Eur. J. Pharmacol., 195 (1991) 181-191.
24. Göthert, M., Schlicker, E. and Köstermann, F., Relationship between transmitter uptake inhibition and effects of α-adrenoceptor agonists on serotonin and noradrenaline release in the rat brain cortex, Naunyn-Schmiedberg's Arch. Pharmacol., 322 (1983) 121-128.
25. 2-adrenoceptor-independent inhibition of noradrenaline release by imidazoline derivatives, Naunyn-Schmiedberg's Arch. Pharmacol., 343 (1991) 271-282.
26. 2-Adrenoceptor-independent inhibition by imidazolines and guanidines of noradrenaline release from peripheral, but not central noradrenergic neurons, Ann. NY Acad. Sci., 763 (1995) 405-419.
27. Gresch, P.J., Sved, A.F., Zigmond, M.J. and Finlay, J.M., Local influence of endogenous norepinephrine on extracellular dopamine in rat medial prefrontal cortex, J. Neurochem., 65 (1995) 111-116.
28. Herrera-Marschitz, M., Goiny, M., Utsumi, H. and Ungerstedt, U., Mesencephalic dopamine innervation of the frontoparietal (sensorimotor) cortex of the rat: a microdialysis study, Neurosci. Lett., 97 (1989) 266-270.
29. 2 -adrenoceptors, Br. J. Pharmacol., 110 (1993) 1635-1639.
30. 2 -adrenoceptors in the rat brain, Mol. Neuropharmacol., 1 (1992) 219-229.
31. Itoh, Y., Oishi, R., Nishibori, M. and Saeki, K., In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism, J. Pharmacol. Exp. Ther., 255 (1990) 1090-1097.
32. Langer, S.Z., Presynaptic regulation of the release of catecholamines, Pharmacol. Rev., 32 (1981) 337-362.
33. L'Heureux, R., Dennis, T., Curet, O. and Scatton, B., Measurement of endogenous noradrenaline release in the rat cerebral cortex in vivo by transcortical dialysis: effects of drugs affecting noradrenergic transmission, J. Neurochem., 46 (1986) 1794-1801.
34. Li, G., Regunathan, S., Barrow, C.J., Eshraghi, J., Cooper, R. and Reis, D.J., Agmatine: an endogenous clonidine-displacing substance in the brain, Science, 263 (1994) 966-969.
35. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
36. Maissonneuve, I.M., Keller, R.W. and Glick, S.D., Similar effects of D-amphetamine and cocaine on extracellular dopamine levels in medial prefrontal cortex of rats, Brain Res., 535 (1990) 221-226.
37. Mallard, N.J., Hudson, A.L. and Nutt, D.J., Characterization and autoradiographical localization of non-adrenoceptor idazoxan binding sites in the rat brain, Br. J. Pharmacol., 106 (1992) 1019-1027.
38. Meeley, M.P., Ernsberger, P.R., Granata, A.R. and Reis, D.J., An endogenous clonidine displacing substance from bovine brain: receptor binding and hypotensive actions in the ventrolateral medulla, Life Sci., 38 (1986) 1119-1126.
39. 2 dopamine receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline in vivo: Selective protection by neuroleptics, J. Pharmacol. Exp. Ther., 233 (1985) 656-662.
40. 2-adrenergic drugs also bind with high affinity to a nonadrenergic site, Mol. Pharmacol., 35 (1989) 324-330.
41. 2A -adrenoceptor subtype mediates antinociception in mice, Eur. J. Pharmacol., 215 (1992) 355-356.
42. 3H]RX821002 (2-methoxy idazoxan) in the human and rat brains, J. Pharmacol. Exp. Ther., 264 (1993) 1187-1197.
43. 2-imidazoline sites in vitro and in vivo, J. Neurochem., 61 (1993) 1602-1610.
44. Moghaddam, B. and Bunney, B.S., Differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: comparison to amphetamine, Synapse, 4 (1989) 156-161.
45. Molderings, G.J., Hentrich, F. and Göthert, M., Pharmacological characterization of the imidazoline receptor which mediates inhibition of noradrenaline release in the rabbit pulmonary artery, Naunyn-Schmiedeberg's Arch. Pharmacol., 344 (1991) 630-638.
46. 2-imidazoline binding sites, Naunyn-Schmiedeberg's Arch. Pharmacol., 351 (1995) 507-516.
47. Munson, P.J. and Rodbard, D., Ligand: a versatile computerized approach for the characterization of ligand binding system, Anal. Biochem., 107 (1980) 220-239.
48. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982, pp. 1-145.
49. 2 adrenergic receptors, J. Pharmacol. Exp. Ther., 272 (1995) 581-587.
50. Pineda, J., Ugedo, L. and García-Sevilla, J.A., Stimulatory effects of clonidine, cirazoline and rilmenidine on locus coeruleus noradrenergic neurones: possible involvement of imidazoline-preferring receptors, Naunyn-Schmiedeberg's Arch. Pharmacol., 348 (1993) 134-140.
51. 2 -adrenoceptors, Naunyn-Schmiedeberg's Arch. Pharmacol., 351 (1995) 10-16.
52. Pozzi, L., Invernizzi, R., Cervo, L., Vallebuona, F. and Samanin, R., Evidence that extracellular concentrations of dopamine are regulated by noradrenergic neurons in the frontal cortex of rats, J. Neurochem., 63 (1994) 195-200.
53. Reis, D.J., Bousquet, P. and Parini, A. (Eds.), Annals of the New York Academy of Sciences, Vol. 763, The imidazoline receptor. Pharmacology, Functions, Ligands, and Relevance to Biology and Medicine, Ann. NY Acad. Sci., 1995, 707 pp.
54. 2-type receptors: pharmacological characterization and relationship to monoamine oxidase, Br. J. Pharmacol., 109 (1993) 625-631.
55. 2-dopamine receptors modulating noradrenaline release in the rat frontal cortex, Ear. J. Pharmacol., 163 (1989) 393-395.
56. Ruiz-Ortega, J.A., Ugedo, L., Pineda, J. and García-Sevilla, J.A., The stimulatory effect of clonidine through imidazoline receptors on locus coeruleus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotoni, Naunyn-Schmiedberg's Arch. Pharmacol., 352 (1995) 121-126.
57. Sharp, T., Zetterström, T. and Ungerstedt, U., An in vivo study of dopamine release and metabolism in rat brain regions using intracerebral dialysis, J. Neurochem., 47 (1986) 113-122.
58. Starke, K., Göthert, M. and Kilbinger, H., Modulation of neurotransmitter release by presynaptic autoreceptors, Physiol. Rev., 69 (1989) 895-989.
59. Stillings, M.R., Chapleo, C.B., Butler, R.C.M., Davis, J.A., England, C.D., Meyers, M., Meyers, P.L., Tweddle, N., Welbourn, A.P., Doxey, J.C. and Smith, C.F.C., α-Adrenoceptor reagents. 3. Synthesis of some 2-substituted 1,4-benzodioxans as selective presynaptic α-adrenoceptor antagonists, J. Med. Chem., 28 (1985) 1054-1062.
60. 2 -adrenoceptors modulating noradrenaline release? Eur. J. Pharmacol., 213 (1992) 305-307.
61. Szabo, B., Urban, R., Limberger, N. and Starke, K., Cardiovascular effects of agmatine, a 'clonidine-displacing substance', in conscious rabbits, Naunyn-Schmiedeberg's Arch. Pharmacol., 351 (1995) 268-273.
62. Szabo, B., Fröhlich, R. and Illes, P., No evidence for functional imidazoline receptors on locus coeruleus neurons, Naunyn-Schmiedeberg's Arch. Pharmacol., 353 (1996) 557-563.
63. 2 -adrenergic receptors by benextramine, Mol. Pharmacol., 31 (1987) 89-96.
64. 2-imidazoline binding sites on monoamine oxidases, J. Biol. Chem., 270 (1995) 9856-9861.
65. Tibiriça, E., Mermet, C., Feldman, J., Gonon, F. and Bousquet, P., Correlation between the inhibitory effect on catecholaminergic ventrolateral medullary neurons and the hypotension evoked by clonidine: a voltammetric approach, J. Pharmacol. Exp. Ther., 250 (1989) 642-647.
66. Tibiriça, E., Feldman, J., Mermet, C., Gonon, F. and Bousquet, P., An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan, J. Pharmacol. Exp. Ther., 256 (1991) 606-613.
67. Ungerstedt, U., Stereotaxic mapping of the monoamine pathways in the rat brain, Acta Physiol. Scand., Suppl. 367 (1971) 1-48.
68. Ungerstedt, U., Herrera-Marschitz, M., Jungnelius, U., Ståhle, L., Tossman, U. and Zetterström, T., Dopamine synaptic mechanisms reflected in studies combining behavioural recordings and brain dialysis. Adv. Biosci., 37 (1982) 219-231.
69. Van Veldhuizen, M.J.A., Feenstra, M.G.P., Heinsbroek, R.P.W. and Boer, G.J., In vivo microdialysis of noradrenaline overflow: effects of α-adrenoceptor agonists and antagonists measured by accumulative concentration-response curves. Br. J. Pharmacol., 109 (1993) 655-660.
70. Van Veldhuizen, M.J.A., Feenstra, M.G.P and Boer, G.J., Regional differences in the in vivo regulation of the extracellular levels of noradrenaline and its metabolites in rat brain, Brain Res., 635 (1994) 238-248.
71. 3H]idazoxan, Neurochem. Int., 17 (1990) 537-546.
72. 2 -adrenoceptors in rat cerebral cortical membranes, Eur. J. Pharmacol., 258 (1994) 67-76.
73. 2 -adrenoceptor antagonists, J. Med. Chem., 29 (1986) 2000-2003.
74. Xu, K., Näveri, L, Frerichs, K.U., Hallenbeck, J.M., Feurstein, G., Davis, J.N. and Sirén, A.L., Extracellular catecholamine levels in rat hippocampus after a selective alpha-2 adrenoceptor antagonist or a selective dopamine uptake inhibitor: evidence for dopamine release from local dopaminergic nerve terminals, J. Pharmacol. Exp. Ther., 267 (1993) 211-217.