Efficient enzymatic regioselective benzoylation of 5-fluorouridine catalysed by Novozym 435

Journal of Chemical Technology and Biotechnology

Volumn 83, Issue 6, 2008, Pages 814-820

  Wu, Jian ^a,b   Zong, Min Hua ^a   Wu, Hong ^a   Lou, Wen Yong ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

5 O benzoyl 5 fluorouridine; 5 fluorouridine; Co solvent; Novozym 435; Regioselective acylation; Vinyl benzoate

Indexed keywords

DRUG PRODUCTS; FLUORINE COMPOUNDS; HEXANE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLVENTS; SYNTHESIS (CHEMICAL);

REGIOSELECTIVE BENZOYLATION; REGIOSELECTIVE ENZYMATIC; TETRAHYDROFURAN (THF);

ENZYME ACTIVITY;

5' O BENZOYL 5 FLUOROURIDINE; ANTINEOPLASTIC AGENT; BENZOIC ACID; FLUOROURIDINE; HEXANE; IMMOBILIZED ENZYME; IMMOBILIZED LIPASE; TETRAHYDROFURAN; TRIACYLGLYCEROL LIPASE; VINYL DERIVATIVE; WATER;

DRUG PRODUCTS; ENZYME ACTIVITY; FLUORINE COMPOUNDS; HEXANE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLVENTS; SYNTHESIS (CHEMICAL);

ACYLATION; ARTICLE; BIOMASS CONVERSION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; DRUG FORMULATION; DRUG STABILITY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; FERMENTATION MEDIUM; REACTION OPTIMIZATION; REACTION TIME; SOLVENT EFFECT; TEMPERATURE MEASUREMENT;

EID: 44649115279     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.1874     Document Type: Article

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