Toxin-resistant sodium channels: Parallel adaptive evolution across a complete gene family

Molecular Biology and Evolution

Volumn 25, Issue 6, 2008, Pages 1016-1024

  Jost, Manda Clair ^a   Hillis, David M ^a   Lu, Ying ^a   Kyle, John W ^b   Fozzard, Harry A ^b   Zakon, Harold H ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Adaptation; Gene families; Parallel evolution; Saxitoxin; Sodium channels; Tetrodotoxin

Indexed keywords

SAXITOXIN; SODIUM CHANNEL; TETRODOTOXIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; EVOLUTIONARY ADAPTATION; GENE DUPLICATION; GENE SEQUENCE; GENETIC RESISTANCE; MOLECULAR CLONING; MOLECULAR EVOLUTION; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PUFFER FISH; SITE DIRECTED MUTAGENESIS; SPECIES DIVERSITY; ADAPTATION; ANIMAL; CLASSIFICATION; DRUG EFFECT; GENETICS; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; POROSITY; PROTEIN TERTIARY STRUCTURE; TETRAODONTIFORMES;

ANIMALIA; TELEOSTEI; TETRAODONTIDAE; VERTEBRATA;

ADAPTATION, BIOLOGICAL; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; EVOLUTION, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHYLOGENY; POROSITY; PROTEIN STRUCTURE, TERTIARY; SAXITOXIN; SODIUM CHANNELS; TETRAODONTIFORMES; TETRODOTOXIN;

EID: 44649109665     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msn025     Document Type: Article

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