Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP

Nature

Volumn 434, Issue 7034, 2005, Pages 763-767

  Bricelj, V Monica ^a   Connell, Laurie ^b   Konoki, Keiichi ^c   MacQuarrie, Scott P ^a   Scheuer, Todd ^c   Catterall, William A ^c   Trainer, Vera L ^d  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF MAINE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d NORTHWEST FISHERIES SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; COASTAL ZONES; ECOSYSTEMS; HUMAN ENGINEERING; SODIUM; TOXIC MATERIALS;

BIVALVE MOLLUSCS; MOLECULAR BASIS; PARALYTIC SHELLFISH POISONING (PSP); SAXITOXIN RESISTANCE; SODIUM CHANNEL MUTATION;

GENETIC ENGINEERING;

SAXITOXIN; SODIUM CHANNEL; SODIUM; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN;

ARTICLE; BINDING SITE; CLAM; CONTROLLED STUDY; ECOSYSTEM; EVOLUTIONARY ADAPTATION; EXPOSURE; FATALITY; GENE MUTATION; HUMAN; MOLLUSC; MORTALITY; NERVE FIBER; NONHUMAN; ORGANISM COMMUNITY; PRIORITY JOURNAL; RISK ASSESSMENT; SEASHORE; SHELLFISH POISONING; SODIUM CONDUCTANCE; SPECIES DIFFERENTIATION; AMINO ACID SEQUENCE; ANIMAL; BIVALVE; CELL LINE; CHEMISTRY; CIGUATERA; DRUG RESISTANCE; ELECTRIC CONDUCTIVITY; GENETIC SELECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PARALYSIS; RISK;

BIVALVIA; MOLLUSCA; MYA ARENARIA;

AMINO ACID SEQUENCE; ANIMALS; BIVALVIA; CELL LINE; CIGUATERA POISONING; DRUG RESISTANCE; ELECTRIC CONDUCTIVITY; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PARALYSIS; RISK; SAXITOXIN; SELECTION (GENETICS); SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; TETRODOTOXIN;

EID: 17144418482     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature03415     Document Type: Article

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