Novel inhibitors for murine and human leukemia inhibitory factor based on fused soluble receptors

Journal of Biological Chemistry

Volumn 283, Issue 10, 2008, Pages 5985-5995

  Metz, Silke ^a   Naeth, Gudrun ^a   Heinrich, Peter C ^a   Müller Newen, Gerhard ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL REACTIONS; ELECTRIC LOAD MANAGEMENT; GENE EXPRESSION; PHOSPHORYLATION;

ANALYSIS OF VARIOUS; BINDING MODULES; CYTOKINE; CYTOKINE INHIBITORS; CYTOKINE RECEPTORS; CYTOKINE TRAPS; CYTOKINES; DO-MAINS; EXTRACELLULAR; EXTRACELLULAR DOMAINS; FUSION PROTEINS; GENE INDUCTIONS; LEUKEMIA INHIBITORY FACTORS; LIF SIGNALS; MALIGNANT DISEASES; POTENT INHIBITORS; SIGNALING RECEPTORS; SOLUBLE RECEPTORS; TARGET GENE EXPRESSIONS; TYROSINE PHOSPHORYLATIONS;

LASER PRODUCED PLASMAS;

GLYCOPROTEIN GP 130; HYBRID PROTEIN; INTERLEUKIN 27; INTERLEUKIN 31; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR INHIBITOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR; ONCOSTATIN M; RECEPTOR BLOCKING AGENT; STAT3 PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; IL6ST PROTEIN, HUMAN; LIF PROTEIN, HUMAN; LIF PROTEIN, MOUSE; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DESIGN; HUMAN; HUMAN CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; DRUG ANTAGONISM; GENETICS; INFLAMMATION; METABOLISM; MOUSE; NEOPLASM; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

MURINAE;

ANIMALS; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOKINE RECEPTOR GP130; CYTOKINES; HUMANS; INFLAMMATION; LEUKEMIA INHIBITORY FACTOR; MICE; NEOPLASMS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, OSM-LIF; RECOMBINANT FUSION PROTEINS; STAT3 TRANSCRIPTION FACTOR;

EID: 44449165636     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706610200     Document Type: Article

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