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Volumn 5, Issue 5, 2008, Pages 0805-0821

A novel tumor-promoting function residing in the 5′ non-coding region of vascular endothelial growth factor mRNA

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYCLOHEXIMIDE; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; PROTEIN SYNTHESIS INHIBITOR; SIGNAL PEPTIDE; SMALL INTERFERING RNA; STAT1 PROTEIN; VASCULOTROPIN; VASCULOTROPIN 165; ANTINEOPLASTIC AGENT; STAT1 PROTEIN, HUMAN; VASCULOTROPIN A;

EID: 44449097601     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0050094     Document Type: Article
Times cited : (18)

References (59)
  • 1
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis-Smyth T (1997) The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25.
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 2
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF (2002) Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20: 4368-4380.
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 3
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM (2005) Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23: 1011-1027.
    • (2005) J Clin Oncol , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 4
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE (2003) Tumorigenesis and the angiogenic switch. Nat Rev Cancer 3: 401-410.
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 5
    • 0032713925 scopus 로고    scopus 로고
    • Vascular endothelial growth factor levels and induction of permeability in malignant pleural effusions
    • Zebrowski BK, Yano S, Liu W, Shaheen RM, Hicklin DJ, et al. (1999) Vascular endothelial growth factor levels and induction of permeability in malignant pleural effusions. Clin Cancer Res 5: 3364-3368.
    • (1999) Clin Cancer Res , vol.5 , pp. 3364-3368
    • Zebrowski, B.K.1    Yano, S.2    Liu, W.3    Shaheen, R.M.4    Hicklin, D.J.5
  • 6
    • 0033050656 scopus 로고    scopus 로고
    • Markedly elevated levels of vascular endothelial growth factor in malignant ascites
    • Zebrowski BK, Liu W, Ramirez K, Akagi Y, Mills GB, et al. (1999) Markedly elevated levels of vascular endothelial growth factor in malignant ascites. Ann Surg Oncol 6: 373-378.
    • (1999) Ann Surg Oncol , vol.6 , pp. 373-378
    • Zebrowski, B.K.1    Liu, W.2    Ramirez, K.3    Akagi, Y.4    Mills, G.B.5
  • 7
    • 0032951394 scopus 로고    scopus 로고
    • Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy
    • Hazelton D, Nicosia RF, Nicosia SV (1999) Vascular endothelial growth factor levels in ovarian cyst fluid correlate with malignancy. Clin Cancer Res 5: 823-829.
    • (1999) Clin Cancer Res , vol.5 , pp. 823-829
    • Hazelton, D.1    Nicosia, R.F.2    Nicosia, S.V.3
  • 8
    • 0036765665 scopus 로고    scopus 로고
    • Correlation of plasma level and immunohistochemical expression of vascular endothelial growth factor in patients with advanced colorectal cancer
    • Minagawa N, Nakayama Y, Hirata K, Onitsuka K, Inoue Y, et al. (2002) Correlation of plasma level and immunohistochemical expression of vascular endothelial growth factor in patients with advanced colorectal cancer. Anticancer Res 22: 2957-2963.
    • (2002) Anticancer Res , vol.22 , pp. 2957-2963
    • Minagawa, N.1    Nakayama, Y.2    Hirata, K.3    Onitsuka, K.4    Inoue, Y.5
  • 9
    • 0035074474 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and soft tissue sarcomas: Tumor expression correlates with grade
    • Chao C, Al-Saleem T, Brooks JJ, Rogatko A, Kraybill WG, et al. (2001) Vascular endothelial growth factor and soft tissue sarcomas: tumor expression correlates with grade. Ann Surg Oncol 8: 260-267.
    • (2001) Ann Surg Oncol , vol.8 , pp. 260-267
    • Chao, C.1    Al-Saleem, T.2    Brooks, J.J.3    Rogatko, A.4    Kraybill, W.G.5
  • 10
    • 0034077964 scopus 로고    scopus 로고
    • Vascular endothelial growth factor, hepatocyte growth factor/scatter factor, basic fibroblast growth factor, and placenta growth factor in human meningiomas and their relation to angiogenesis and malignancy
    • discussion 947-948
    • Lamszus K, Lengler U, Schmidt NO, Stavrou D, Ergun S, et al. (2000) Vascular endothelial growth factor, hepatocyte growth factor/scatter factor, basic fibroblast growth factor, and placenta growth factor in human meningiomas and their relation to angiogenesis and malignancy. Neurosurgery 46: 938-947; discussion 947-948.
    • (2000) Neurosurgery , vol.46 , pp. 938-947
    • Lamszus, K.1    Lengler, U.2    Schmidt, N.O.3    Stavrou, D.4    Ergun, S.5
  • 11
    • 0041698508 scopus 로고    scopus 로고
    • Changes in circulating VEGF levels in relation to clinical response during chemotherapy for metastatic cancer
    • Lissoni P, Rovelli F, Malugani F, Brivio F, Fumagalli L, et al. (2003) Changes in circulating VEGF levels in relation to clinical response during chemotherapy for metastatic cancer. Int J Biol Markers 18: 152-155.
    • (2003) Int J Biol Markers , vol.18 , pp. 152-155
    • Lissoni, P.1    Rovelli, F.2    Malugani, F.3    Brivio, F.4    Fumagalli, L.5
  • 12
    • 34247170045 scopus 로고    scopus 로고
    • Circulating VEGF reduction, response and outcome in advanced colorectal cancer patients treated with cetuximab plus irinotecan
    • Vincenzi B, Santini D, Russo A, Gavasci M, Battistoni F, et al. (2007) Circulating VEGF reduction, response and outcome in advanced colorectal cancer patients treated with cetuximab plus irinotecan. Pharmacogenomics 8: 319-327.
    • (2007) Pharmacogenomics , vol.8 , pp. 319-327
    • Vincenzi, B.1    Santini, D.2    Russo, A.3    Gavasci, M.4    Battistoni, F.5
  • 13
    • 30944440262 scopus 로고    scopus 로고
    • Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF)
    • Byrne AM, Bouchier-Hayes DJ, Harmey JH (2005) Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med 9: 777-794.
    • (2005) J Cell Mol Med , vol.9 , pp. 777-794
    • Byrne, A.M.1    Bouchier-Hayes, D.J.2    Harmey, J.H.3
  • 14
    • 30944446883 scopus 로고    scopus 로고
    • Lessons from phase III clinical trials on anti-VEGF therapy for cancer
    • Jain RK, Duda DG, Clark JW, Loeffler JS (2006) Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 3: 24-40.
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 24-40
    • Jain, R.K.1    Duda, D.G.2    Clark, J.W.3    Loeffler, J.S.4
  • 15
    • 3042538425 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer
    • Sandler AB, Johnson DH, Herbst RS (2004) Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer. Clin Cancer Res 10: 4258s-4262s.
    • (2004) Clin Cancer Res , vol.10
    • Sandler, A.B.1    Johnson, D.H.2    Herbst, R.S.3
  • 16
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • doi: 10.1371/journal.pmed.0040186
    • Lee TH, Seng S, Sekine M, Hinton C, Fu Y, et al. (2007) Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 4: e186. doi: 10.1371/journal.pmed.0040186
    • (2007) PLoS Med , vol.4
    • Lee, T.H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5
  • 17
    • 24744440117 scopus 로고    scopus 로고
    • Non-coding RNAs: New players in eukaryotic biology
    • Costa FF (2005) Non-coding RNAs: new players in eukaryotic biology. Gene 357: 83-94.
    • (2005) Gene , vol.357 , pp. 83-94
    • Costa, F.F.1
  • 18
    • 0027140480 scopus 로고
    • Tumor suppression by RNA from the 3′ untranslated region of alpha-tropomyosin
    • Rastinejad F, Conboy MJ, Rando TA, Blau HM (1993) Tumor suppression by RNA from the 3′ untranslated region of alpha-tropomyosin. Cell 75: 1107-1117.
    • (1993) Cell , vol.75 , pp. 1107-1117
    • Rastinejad, F.1    Conboy, M.J.2    Rando, T.A.3    Blau, H.M.4
  • 19
    • 0141816859 scopus 로고    scopus 로고
    • Tumor suppression by the prohibitin gene 39untranslated region RNA in human breast cancer
    • Manjeshwar S, Branam DE, Lerner MR, Brackett DJ, Jupe ER (2003) Tumor suppression by the prohibitin gene 39untranslated region RNA in human breast cancer. Cancer Res 63: 5251-5256.
    • (2003) Cancer Res , vol.63 , pp. 5251-5256
    • Manjeshwar, S.1    Branam, D.E.2    Lerner, M.R.3    Brackett, D.J.4    Jupe, E.R.5
  • 20
    • 0029776812 scopus 로고    scopus 로고
    • Suppression of malignancy by the 3′ untranslated regions of ribonucleotide reductase R1 and R2 messenger RNAs
    • Fan H, Villegas C, Huang A, Wright JA (1996) Suppression of malignancy by the 3′ untranslated regions of ribonucleotide reductase R1 and R2 messenger RNAs. Cancer Res 56: 4366-4369.
    • (1996) Cancer Res , vol.56 , pp. 4366-4369
    • Fan, H.1    Villegas, C.2    Huang, A.3    Wright, J.A.4
  • 21
    • 0037811247 scopus 로고    scopus 로고
    • Inhibition of tumorigenicity by the 5′-untranslated RNA of the human c-myc P0 transcript
    • Blume SW, Miller DM, Guarcello V, Shrestha K, Meng Z, et al. (2003) Inhibition of tumorigenicity by the 5′-untranslated RNA of the human c-myc P0 transcript. Exp Cell Res 288: 131-142.
    • (2003) Exp Cell Res , vol.288 , pp. 131-142
    • Blume, S.W.1    Miller, D.M.2    Guarcello, V.3    Shrestha, K.4    Meng, Z.5
  • 22
    • 0031741862 scopus 로고    scopus 로고
    • Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA
    • Huez I, Creancier L, Audigier S, Gensac MC, Prats AC, et al. (1998) Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol Cell Biol 18: 6178-6190.
    • (1998) Mol Cell Biol , vol.18 , pp. 6178-6190
    • Huez, I.1    Creancier, L.2    Audigier, S.3    Gensac, M.C.4    Prats, A.C.5
  • 23
    • 0032537757 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription
    • Akiri G, Nahari D, Finkelstein Y, Le SY, Elroy-Stein O, et al. (1998) Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription. Oncogene 17: 227-236.
    • (1998) Oncogene , vol.17 , pp. 227-236
    • Akiri, G.1    Nahari, D.2    Finkelstein, Y.3    Le, S.Y.4    Elroy-Stein, O.5
  • 24
    • 0035208145 scopus 로고    scopus 로고
    • New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation
    • Huez I, Bornes S, Bresson D, Creancier L, Prats H (2001) New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation. Mol Endocrinol 15: 2197-2210.
    • (2001) Mol Endocrinol , vol.15 , pp. 2197-2210
    • Huez, I.1    Bornes, S.2    Bresson, D.3    Creancier, L.4    Prats, H.5
  • 25
    • 9444255136 scopus 로고    scopus 로고
    • Hyperglycemia upregulates translation of the fibroblast growth factor 2 mRNA in mouse aorta via internal ribosome entry site
    • Teshima-Kondo S, Kondo K, Prado-Lourenco L, Gonzalez-Herrera IG, Rokutan K, et al. (2004) Hyperglycemia upregulates translation of the fibroblast growth factor 2 mRNA in mouse aorta via internal ribosome entry site. FASEB J: 03-1118fje.
    • (2004) FASEB J
    • Teshima-Kondo, S.1    Kondo, K.2    Prado-Lourenco, L.3    Gonzalez-Herrera, I.G.4    Rokutan, K.5
  • 26
    • 2442559239 scopus 로고    scopus 로고
    • Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences
    • Bornes S, Boulard M, Hieblot C, Zanibellato C, Iacovoni JS, et al. (2004) Control of the vascular endothelial growth factor internal ribosome entry site (IRES) activity and translation initiation by alternatively spliced coding sequences. J Biol Chem 279: 18717-18726.
    • (2004) J Biol Chem , vol.279 , pp. 18717-18726
    • Bornes, S.1    Boulard, M.2    Hieblot, C.3    Zanibellato, C.4    Iacovoni, J.S.5
  • 27
    • 4344604206 scopus 로고    scopus 로고
    • Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs
    • Martineau Y, Le Bec C, Monbrun L, Allo V, Chiu IM, et al. (2004) Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol 24: 7622-7635.
    • (2004) Mol Cell Biol , vol.24 , pp. 7622-7635
    • Martineau, Y.1    Le Bec, C.2    Monbrun, L.3    Allo, V.4    Chiu, I.M.5
  • 28
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • Zuker M (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucl Acids Res 31: 3406-3415.
    • (2003) Nucl Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 29
    • 1342324604 scopus 로고    scopus 로고
    • Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells
    • Kawahara T, Kuwano Y, Teshima-Kondo S, Takeya R, Sumimoto H, et al. (2004) Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells. J Immunol 172: 3051-3058.
    • (2004) J Immunol , vol.172 , pp. 3051-3058
    • Kawahara, T.1    Kuwano, Y.2    Teshima-Kondo, S.3    Takeya, R.4    Sumimoto, H.5
  • 31
    • 0345306600 scopus 로고    scopus 로고
    • Tight control of platelet-derived growth factor B/c-sis expression by interplay between the 5′-untranslated region sequence and the major upstream promoter
    • Han B, Dong Z, Zhang JT (2003) Tight control of platelet-derived growth factor B/c-sis expression by interplay between the 5′-untranslated region sequence and the major upstream promoter. J Biol Chem 278: 46983-46993.
    • (2003) J Biol Chem , vol.278 , pp. 46983-46993
    • Han, B.1    Dong, Z.2    Zhang, J.T.3
  • 32
    • 0036043689 scopus 로고    scopus 로고
    • Translational control of gene expression: Role of IRESs and consequences for cell transformation and angiogenesis
    • Prats AC, Prats H (2002) Translational control of gene expression: role of IRESs and consequences for cell transformation and angiogenesis. Prog Nucleic Acid Res Mol Biol 72: 367-413.
    • (2002) Prog Nucleic Acid Res Mol Biol , vol.72 , pp. 367-413
    • Prats, A.C.1    Prats, H.2
  • 33
    • 0036625960 scopus 로고    scopus 로고
    • The role of STATs in apoptosis
    • Battle TE, Frank DA (2002) The role of STATs in apoptosis. Curr Mol Med 2: 381-392.
    • (2002) Curr Mol Med , vol.2 , pp. 381-392
    • Battle, T.E.1    Frank, D.A.2
  • 35
    • 0025293764 scopus 로고
    • Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: A review
    • Wadler S, Schwartz EL (1990) Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review. Cancer Res 50: 3473-3486.
    • (1990) Cancer Res , vol.50 , pp. 3473-3486
    • Wadler, S.1    Schwartz, E.L.2
  • 36
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan GI, Vousden KH (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411: 342-348.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 37
    • 10944257459 scopus 로고    scopus 로고
    • Molecular signaling regulating anchorage-independent growth of cancer cells
    • Wang LH (2004) Molecular signaling regulating anchorage-independent growth of cancer cells. Mt Sinai J Med 71: 361-367.
    • (2004) Mt Sinai J Med , vol.71 , pp. 361-367
    • Wang, L.H.1
  • 38
    • 34548799176 scopus 로고    scopus 로고
    • Translational control of the interferon regulatory factor 2 mRNA by IRES element
    • Dhar D, Roy S, Das S (2007) Translational control of the interferon regulatory factor 2 mRNA by IRES element. Nucleic Acids Res 35: 5409-5421.
    • (2007) Nucleic Acids Res , vol.35 , pp. 5409-5421
    • Dhar, D.1    Roy, S.2    Das, S.3
  • 39
    • 0032560475 scopus 로고    scopus 로고
    • Demonstration of an interferon gamma -dependent tumor surveillance system in immunocompetent mice
    • Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, et al. (1998) Demonstration of an interferon gamma -dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A 95: 7556-7561.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7556-7561
    • Kaplan, D.H.1    Shankaran, V.2    Dighe, A.S.3    Stockert, E.4    Aguet, M.5
  • 40
    • 0041662272 scopus 로고    scopus 로고
    • Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence
    • Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, et al. (2003) Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 424: 516-523.
    • (2003) Nature , vol.424 , pp. 516-523
    • Takaoka, A.1    Hayakawa, S.2    Yanai, H.3    Stoiber, D.4    Negishi, H.5
  • 41
    • 0037061736 scopus 로고    scopus 로고
    • Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells
    • Huang S, Bucana CD, Van Arsdall M, Fidler IJ (2002) Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene 21: 2504-2512.
    • (2002) Oncogene , vol.21 , pp. 2504-2512
    • Huang, S.1    Bucana, C.D.2    Van Arsdall, M.3    Fidler, I.J.4
  • 42
    • 0030712998 scopus 로고    scopus 로고
    • Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma
    • Wong LH, Krauer KG, Hatzinisiriou I, Estcourt MJ, Hersey P, et al. (1997) Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma. J Biol Chem 272: 28779-28785.
    • (1997) J Biol Chem , vol.272 , pp. 28779-28785
    • Wong, L.H.1    Krauer, K.G.2    Hatzinisiriou, I.3    Estcourt, M.J.4    Hersey, P.5
  • 43
    • 0031659236 scopus 로고    scopus 로고
    • Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line
    • Abril E, Real LM, Serrano A, Jimenez P, Garcia A, et al. (1998) Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line. Cancer Immunol Immunother 47: 113-120.
    • (1998) Cancer Immunol Immunother , vol.47 , pp. 113-120
    • Abril, E.1    Real, L.M.2    Serrano, A.3    Jimenez, P.4    Garcia, A.5
  • 44
    • 0037454239 scopus 로고    scopus 로고
    • Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis
    • von Marschall Z, Scholz A, Cramer T, Schafer G, Schirner M, et al. (2003) Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis. J Natl Cancer Inst 95: 437-448.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 437-448
    • von Marschall, Z.1    Scholz, A.2    Cramer, T.3    Schafer, G.4    Schirner, M.5
  • 45
    • 6044276873 scopus 로고    scopus 로고
    • Interferon-alpha: Regulatory effects on cell cycle and angiogenesis
    • Rosewicz S, Detjen K, Scholz A, von Marschall Z (2004) Interferon-alpha: regulatory effects on cell cycle and angiogenesis. Neuroendocrinology 80 Suppl 1: 85-93.
    • (2004) Neuroendocrinology , vol.80 , Issue.SUPPL. 1 , pp. 85-93
    • Rosewicz, S.1    Detjen, K.2    Scholz, A.3    von Marschall, Z.4
  • 46
    • 33645731313 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis
    • Battle TE, Lynch RA, Frank DA (2006) Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. Cancer Res 66: 3649-3657.
    • (2006) Cancer Res , vol.66 , pp. 3649-3657
    • Battle, T.E.1    Lynch, R.A.2    Frank, D.A.3
  • 47
    • 1042301419 scopus 로고    scopus 로고
    • STAT1-induced apoptosis is mediated by Caspases 2, 3, and 7
    • Sironi JJ, Ouchi T (2004) STAT1-induced apoptosis is mediated by Caspases 2, 3, and 7. J Biol Chem 279: 4066-4074.
    • (2004) J Biol Chem , vol.279 , pp. 4066-4074
    • Sironi, J.J.1    Ouchi, T.2
  • 48
    • 0031868650 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma
    • Chan AS, Leung SY, Wong MP, Yuen ST, Cheung N, et al. (1998) Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma. Am J Surg Pathol 22: 816-826.
    • (1998) Am J Surg Pathol , vol.22 , pp. 816-826
    • Chan, A.S.1    Leung, S.Y.2    Wong, M.P.3    Yuen, S.T.4    Cheung, N.5
  • 49
    • 0027482251 scopus 로고
    • Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract
    • Brown LF, Berse B, Jackman RW, Tognazzi K, Manseau EJ, et al. (1993) Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 53: 4727-4735.
    • (1993) Cancer Res , vol.53 , pp. 4727-4735
    • Brown, L.F.1    Berse, B.2    Jackman, R.W.3    Tognazzi, K.4    Manseau, E.J.5
  • 50
    • 0037169360 scopus 로고    scopus 로고
    • Human interferon-gamma mRNA autoregulates its translation through a pseudo-knot that activates the interferon-inducible protein kinase PKR
    • Ben-Asouli Y, Banai Y, Pel-Or Y, Shir A, Kaempfer R (2002) Human interferon-gamma mRNA autoregulates its translation through a pseudo-knot that activates the interferon-inducible protein kinase PKR. Cell 108: 221-232.
    • (2002) Cell , vol.108 , pp. 221-232
    • Ben-Asouli, Y.1    Banai, Y.2    Pel-Or, Y.3    Shir, A.4    Kaempfer, R.5
  • 51
    • 0030033398 scopus 로고    scopus 로고
    • In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3′ untranslated regions of human alpha -tropomyosin
    • Davis S, Watson JC (1996) In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3′ untranslated regions of human alpha -tropomyosin. Proc Natl Acad Sci U S A 93: 508-513.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 508-513
    • Davis, S.1    Watson, J.C.2
  • 52
    • 0033572827 scopus 로고    scopus 로고
    • A cis-acting element in the 3′-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR
    • Osman F, Jarrous N, Ben-Asouli Y, Kaempfer R (1999) A cis-acting element in the 3′-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR. Genes Dev 13: 3280-3293.
    • (1999) Genes Dev , vol.13 , pp. 3280-3293
    • Osman, F.1    Jarrous, N.2    Ben-Asouli, Y.3    Kaempfer, R.4
  • 53
    • 33845627785 scopus 로고    scopus 로고
    • Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action
    • Garcia MA, Gil J, Ventoso I, Guerra S, Domingo E, et al. (2006) Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol Mol Biol Rev 70: 1032-1060.
    • (2006) Microbiol Mol Biol Rev , vol.70 , pp. 1032-1060
    • Garcia, M.A.1    Gil, J.2    Ventoso, I.3    Guerra, S.4    Domingo, E.5
  • 54
    • 0027457944 scopus 로고
    • Genetic complementation reveals a novel regulatory role for 3′ untranslated regions in growth and differentiation
    • Rastinejad F, Blau HM (1993) Genetic complementation reveals a novel regulatory role for 3′ untranslated regions in growth and differentiation. Cell 72: 903-917.
    • (1993) Cell , vol.72 , pp. 903-917
    • Rastinejad, F.1    Blau, H.M.2
  • 55
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • Gerber HP, Ferrara N (2005) Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 65: 671-680.
    • (2005) Cancer Res , vol.65 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 56
    • 0030856731 scopus 로고    scopus 로고
    • Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
    • Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, et al. (1997) Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 57: 4593-4599.
    • (1997) Cancer Res , vol.57 , pp. 4593-4599
    • Presta, L.G.1    Chen, H.2    O'Connor, S.J.3    Chisholm, V.4    Meng, Y.G.5
  • 57
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, et al. (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350: 2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3    Cartwright, T.4    Hainsworth, J.5
  • 58
    • 20044364346 scopus 로고    scopus 로고
    • Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
    • Miller KD, Chap LI, Holmes FA, Cobleigh MA, Marcom PK, et al. (2005) Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 23: 792-799.
    • (2005) J Clin Oncol , vol.23 , pp. 792-799
    • Miller, K.D.1    Chap, L.I.2    Holmes, F.A.3    Cobleigh, M.A.4    Marcom, P.K.5
  • 59
    • 34247849335 scopus 로고    scopus 로고
    • Target practice: Lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer
    • Los M, Roodhart JML, Voest EE (2007) Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer. Oncologist 12: 443-450.
    • (2007) Oncologist , vol.12 , pp. 443-450
    • Los, M.1    Roodhart, J.M.L.2    Voest, E.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.