Atherosclerosis - New targets and therapeutics

Current Medicinal Chemistry: Cardiovascular and Hematological Agents

Volumn 2, Issue 4, 2004, Pages 327-334

  Pillarisetti, Sivaram ^a   Alexander, Christopher W ^a   Saxena, Uday ^a  

^a Reddy US Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4,6 DI TERT BUTYL 2,3 DIHYDRO 5 HYDROXY 2,2 DIPENTYLBENZOFURAN; ANTILIPEMIC AGENT; ANTIOXIDANT; AVASIMIBE; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLESTEROL ESTER TRANSFER PROTEIN; DARAPLADIB; EFLUCIMIBE; ETC 216; EVEROLIMUS; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PACLITAXEL; PACTIMIBE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PRACTIMIBE; PROBUCOL SUCCINATE; PROTEOHEPARAN SULFATE; RAPAMYCIN; TORCETRAPIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ATHEROSCLEROSIS; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CLINICAL TRIAL; DRUG INDICATION; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; HUMAN; LIPID METABOLISM; NONHUMAN; OXIDATIVE STRESS; RESTENOSIS; REVIEW; RISK FACTOR; SMOOTH MUSCLE FIBER;

ARTERIOSCLEROSIS; DRUG DESIGN; HUMANS; LIPIDS; RISK FACTORS;

EID: 4444384223     PISSN: 15680169     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568016043356246     Document Type: Review

References (54)

1. Kannel, W.B. Clin. Ther., 1998, 20, B2.
2. Ross, R. N. Engl. J. Med., 1999, 340, 115.
3. Libby, P. Nature, 2002, 26, 868.
4. Williams, K.J.; Tabas, I. Arterioscler. Thromb. Vasc. Biol., 1995, 15, 551.
5. Fuster, V.; Gotto, A.M. Jr. Circulation, 2000, 102, IV94.
6. Rosenberg, R.D.; Shworak, N.W.; Liu, J.; Schwartz, J.J.; Zhang, L. J. Clin. Invest., 1997, 99, 2062.
7. Pillarisetti, S. Trends Cardiovas. Med., 2000, 10, 60.
8. Ganesh, S.K.; Nass, C.M.; Blumenthal, R.S. J. Cardiovasc. Risk, 2003, 10, 155.
9. Ballantyne, C.M. Curr. Atheroscler. Rep., 1999, 1, 6.
10. Rader, D. J. Am. J. Cardiol., 2002, 90, 62i.
11. Assmann, G.; Nofer, J.R. Annu. Rev. Med., 2003, 54, 321.
12. Barter, P; Kastelein, J.; Nunn, A.; Hobbs, R.; Future Forum Editorial Board, Atherosclerosis, 2003, 168, 195.
13. Newton, R.S.; Krause, B.R. Atheroscler. Suppl., 2002, 3, 31.
14. Barter, P.J.; Brewer, H.B.Jr.; Chapman, M.J.; Hennekens, C.H.; Rader, D.J.; Tal, A.R. Arterioscler. Thromb. Vasc. Biol., 2003, 23, 160.
15. Oram, J.F. Arterioscler. Thromb. Vasc. Biol., 2003, 23, 720.
16. Chawla, A.; Boisvert, W.A.; Lee, C.H.; Laffitte, B.A.; Barak, Y.; Joseph, S.B.; Liao, D.; Nagy, L.; Edwards, P.A.; Curtiss, L.K.; Evans, R.M.; Tontonoz, P.A. Mol. Cell, 2001, 7, 161.
17. Joseph, S.B.; McKilligin, E.; Pei, L; Watson, M.A.; Collins, A.R.; Laffitte, B.A.; Chen, M.; Noh, G.; Goodman, J.; Hagger, G.N.; Tran, J.; Tippin, T.K.; Wang, X.; Lusis, A.J.; Hsueh, W.A.; Law, R.E.; Collins, J.L.; Willson, T.M.; Tontonoz, P. Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 7604.
18. Grefhorst, A.; Elzinga, B.M.; Voshol, P.J.; Plosch, T.; Kok, T.; Bloks, V.W.; van der Sluijs, F.H.; Havekes, L.M.; Romijn, J.A.; Verkade, H.J.; Kuipers, F. J. Biol. Chem., 2002, 277, 34182.
19. Rudel, L.L.; Lee, R.G.; Cockman, T.L. Curr. Opin. Lipidol., 2001, 12, 121.
20. Llaverias, G.; Laguna, J.C.; Alegret, M. Pharmacology Cardiovasc. Drug Rev., 2003, 21, 33.
21. Burnett, J.R.; Fabre, P. Curr. Opin. Investig. Drugs, 2003, 4, 347.
22. Ridker, P.M. Circulation, 2003, 107, 363.
23. Rifai, N.; Ridker, P.M. Curr. Opin. Lipidol., 2002, 13, 383.
24. Gotto, A.M.Jr. Prev. Cardiol., 2002, 5, 200.
25. Verma, S.; Li, S.H.; Badiwala, M.V.; Weisel, R.D.; Fedak, P.W.; Li, R.K.; Dhillon, B.; Mickle, D.A. Circulation, 2002, 105, 1890.
26. Pasceri, V.; Willerson, J.T.; Yeh, E.T. Circulation, 2000, 102, 2165.
27. Heinecke, J.W. Am. J. Cardiol., 2003, 91, 12A.
28. Harrison, D.; Griendling, K.K.; Landmesser, U.; Hornig, B.; Drexler, H. Am. J. Cardiol., 2003, 91, 7A.
29. Abe, J.; Berk, B.C. Trends Cardiovasc. Med., 1998, 8, 59.
30. Esposito, K.; Nappo, F.; Marfella, R.; Giugliano, G.; Giugliano, F.; Ciotola, M.; Quagliaro, L.; Ceriello, A.; Giugliano, D. Circulation, 2002, 106, 2067.
31. Steinberg, D.; Witztum, J.L. Circulation, 2002, 105, 2107.
32. Parthasarathy, S.; Khan-Merchant, N.; Penumetcha, M.; Khan, B. V.; Santanam, N. Curr. Atheroscler. Rep., 2001, 392.
33. Wasserman, M.A.; Sundell, C.L.; Kunsch, C.; Edwards, D.; Meng, C.Q.; Medford, R.M. Am. J. Cardiol., 2003, 91, 34A.
34. Tardif, J.C. Am. J. Cardiol., 2003, 91, 41A.
35. Tamura, K.; Kato, Y.; Ishikawa, A.; Kato, Y.; Himori, M; Yoshida, M.; Takashima, Y.; Suzuki, T.; Kawabe, Y.; Cynshi, O.; Kodama, T.; Niki, E.; Shimizu, M. J. Med. Chem., 2003, 46, 3083.
36. Meng, C.Q. Curr. Opin. Investi.g Drugs, 2003, 4, 342.
37. Macphee, C. H. Curr. Opin. Pharmacol., 2001, 121.
38. Caslake, M.J.; Packard, C.J.; Suckling, K.E.; Holmes, S.D.; Chamberlain, P.; Macphee, C.H. Atherosclerosis, 2000, 150, 413.
39. Dzau, V.J.; Braun-Dullaeus, R.C.; Sedding, D.G. Nat. Med., 2002, 8, 1249.
40. Geng, Y.J.; Libby, P. Arterioscler. Thromb. Vasc. Biol., 2002, 22, 1370.
41. De Feyter, P.J.; Smits, P.C.; Rensing, B.J.; Vos, J.; Van der Giessen, W.J.; Sianos, G.; Serruys, P.W. J. Interv. Cardiol., 2002, 15, 467.
42. Grube, E.; Bullesfeld, L. J. Interv. Cardiol., 2002, 15, 471.
43. Fattori, R.; Piva, T. Lancet, 2003, 361, 247.
44. Virmani, R.; Kolodgie, F.D.; Farb, A.; Lafont, A. Heart, 2003, 89, 133.
45. Nugent, M.A.; Nugent, H.M.; Iozzo R.V.; Sanchack, K.; Edelman, E.R. Proc. Natl. Acad. Sci. U.S.A., 2000, 97, 6722.
46. Engelberg, H. Atherosclerosis, 2001, 159, 253.
47. Hollman, J.A.; Schmidt, von Bassewit, D.; Buddecke, E. Arteiosclerosis, 1989, 9, 154.
48. Kruse, R.; Merten, M.; Yoshida, K.; Schmidt, A.; Volker, W.; Buddecke, E. Basic Res. Cardiol., 1996, 91, 344.
49. Ramasamy, S.; Lipke, D.W.; McClain, C.J.; Hennig, B. J. Cell Physiol., 1995 162, 119.
50. Fuji, N.; Kaji, T.; Akai, T.; Koizumi, F. Thromb. Res., 1997, 88, 299.
51. Ramasamy, S.; Lipke, D.W.; Boissonneault, G.A.; Guo, H.; Hennig, B. Atherosclerosis, 1996, 120, 199.
52. Pillarisetti, S.; Obunike, J.C.; Goldberg, I.J. J. Biol. Chem., 1995, 270, 29760.
53. Pillarisetti, S.; Paka, L.; Obunike, J.C.; Berglund, L.; Goldberg, I.J. J. Clin. Invest., 1997, 100, 867.
54. Ballantyne, C.M. Clin. Cardiol., 2001, 8 Suppl. III, 13.