-
1
-
-
0033934734
-
Mitochondria and the pathogenesis of ALS
-
Beal M. F. (2000) Mitochondria and the pathogenesis of ALS. Brain. 123, 1291-1292.
-
(2000)
Brain
, vol.123
, pp. 1291-1292
-
-
Beal, M.F.1
-
2
-
-
0033803718
-
Neurotoxicity of calcineurin inhibitors: Impact and clinical management
-
Bechstein W. O. (2000) Neurotoxicity of calcineurin inhibitors: impact and clinical management. Transpl. Int. 13, 313-326.
-
(2000)
Transpl. Int.
, vol.13
, pp. 313-326
-
-
Bechstein, W.O.1
-
3
-
-
0033807443
-
Increased oxidative damage to DNA in ALS patients
-
Bogdanov M., Brown H. R. Jr, Matson W., Smart R., Hayden D., O'Donnell H., Beal M. F. and Cudkowicz M. (2000) Increased oxidative damage to DNA in ALS patients. Free Radic. Biol. Med. 29, 652-658.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 652-658
-
-
Bogdanov, M.1
Brown Jr., H.R.2
Matson, W.3
Smart, R.4
Hayden, D.5
O'Donnell, H.6
Beal, M.F.7
Cudkowicz, M.8
-
4
-
-
0034283331
-
Blood oxidative stress in amyotrophic lateral sclerosis
-
Bonnefont-Rousselot D., Lacomblez L., Jaudon M., Lepage S., Salachas F., Bensimon G., Bizard C., Doppler V., Delattre J. and Meininger V. (2000) Blood oxidative stress in amyotrophic lateral sclerosis. J. Neurol. Sci. 178, 57-62.
-
(2000)
J. Neurol. Sci.
, vol.178
, pp. 57-62
-
-
Bonnefont-Rousselot, D.1
Lacomblez, L.2
Jaudon, M.3
Lepage, S.4
Salachas, F.5
Bensimon, G.6
Bizard, C.7
Doppler, V.8
Delattre, J.9
Meininger, V.10
-
5
-
-
0344178211
-
Characterization of calcineurin in human neutrophils. Inhibitory effect of hydrogen peroxide on its enzyme activity and on NF-kappaB DNA binding
-
Carballo M., Marquez G., Conde M., Martin-Nieto J., Monteseirin J., Conde J., Pintado E. and Sobrino F. (1999) Characterization of calcineurin in human neutrophils. Inhibitory effect of hydrogen peroxide on its enzyme activity and on NF-kappaB DNA binding. J. Biol. Chem. 274, 93-100.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 93-100
-
-
Carballo, M.1
Marquez, G.2
Conde, M.3
Martin-Nieto, J.4
Monteseirin, J.5
Conde, J.6
Pintado, E.7
Sobrino, F.8
-
6
-
-
0031559896
-
2+ concentration in transfected neuroblastoma SH-SY5Y cells
-
2+ concentration in transfected neuroblastoma SH-SY5Y cells. FEBS Lett. 414, 365-368.
-
(1997)
FEBS Lett.
, vol.414
, pp. 365-368
-
-
Carrì, M.T.1
Ferri, A.2
Battistoni, A.3
Famhy, L.4
Gabbianelli, R.5
Poccia, F.6
Rotilio, G.7
-
7
-
-
0042165931
-
Neurodegeneration in amyotrophic lateral sclerosis: The role of oxidative stress and altered homeostasis of metals
-
Carrì M. T., Ferri A., Cozzolino M., Calabrese L. and Rotilio G. (2003) Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals. Brain Res. Bull. 61, 365-374.
-
(2003)
Brain Res. Bull.
, vol.61
, pp. 365-374
-
-
Carrì, M.T.1
Ferri, A.2
Cozzolino, M.3
Calabrese, L.4
Rotilio, G.5
-
8
-
-
0037293061
-
Drug therapy for amyotrophic lateral sclerosis: Where are we now?
-
Carter G. T., Krivickas L. S., Weydt P., Weiss M. D. and Miller R. G. (2003) Drug therapy for amyotrophic lateral sclerosis: Where are we now? Idrugs 6, 147-153.
-
(2003)
Idrugs
, vol.6
, pp. 147-153
-
-
Carter, G.T.1
Krivickas, L.S.2
Weydt, P.3
Weiss, M.D.4
Miller, R.G.5
-
9
-
-
0036892743
-
Oxidative modulation of NF-κB in human cells expressing mutant FALS-typical superoxide dismutases
-
Casciati A., Ferri A., Cozzolino M., Celsi F., Nencini M., Rotilio G. and Carrì M. T. (2002) Oxidative modulation of NF-κB in human cells expressing mutant FALS-typical superoxide dismutases. J. Neurochem. 83, 1019-1029.
-
(2002)
J. Neurochem.
, vol.83
, pp. 1019-1029
-
-
Casciati, A.1
Ferri, A.2
Cozzolino, M.3
Celsi, F.4
Nencini, M.5
Rotilio, G.6
Carrì, M.T.7
-
10
-
-
0029809528
-
Amyotrophic lateral sclerosis: Oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes
-
Curti D., Malaspina A., Facchetti G., Camana C., Mazzini L., Tosca P., Zerbi F. and Ceroni M. (1996) Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes. Neurology 47, 1060-1064.
-
(1996)
Neurology
, vol.47
, pp. 1060-1064
-
-
Curti, D.1
Malaspina, A.2
Facchetti, G.3
Camana, C.4
Mazzini, L.5
Tosca, P.6
Zerbi, F.7
Ceroni, M.8
-
11
-
-
0027453536
-
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
-
Dawson T. M., Steiner J. P., Dawson V. L., Dinerman J. L., Uhl G. R. and Snyder S. H. (1993) Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc. Natl. Acad. Sci. USA 90, 9808-9812.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9808-9812
-
-
Dawson, T.M.1
Steiner, J.P.2
Dawson, V.L.3
Dinerman, J.L.4
Uhl, G.R.5
Snyder, S.H.6
-
12
-
-
0034078320
-
FK506, an immunosuppressant targeting calcineurin function
-
Dumont F. J. (2000) FK506, an immunosuppressant targeting calcineurin function. Curr. Med. 7, 731-748.
-
(2000)
Curr. Med.
, vol.7
, pp. 731-748
-
-
Dumont, F.J.1
-
13
-
-
0030813067
-
Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis
-
Ferrante R. J., Browne S. E., Shinobu L. A., Bowling A. C., Baik M. J., MacGarvey U., Kowall N. W., Brown R. H. Jr and Beal M. F. (1997) Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J. Neurochem. 69, 2064-2074.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2064-2074
-
-
Ferrante, R.J.1
Browne, S.E.2
Shinobu, L.A.3
Bowling, A.C.4
Baik, M.J.5
MacGarvey, U.6
Kowall, N.W.7
Brown Jr., R.H.8
Beal, M.F.9
-
14
-
-
0033914937
-
Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase
-
Ferri A., Gabbianelli R., Casciati A., Paolucci E., Rotilio G. and Carrì M. T. (2000) Calcineurin activity is regulated both by redox compounds and by mutant familial amyotrophic lateral sclerosis-superoxide dismutase. J. Neurochem. 75, 606-613.
-
(2000)
J. Neurochem.
, vol.75
, pp. 606-613
-
-
Ferri, A.1
Gabbianelli, R.2
Casciati, A.3
Paolucci, E.4
Rotilio, G.5
Carrì, M.T.6
-
15
-
-
0034763797
-
Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis
-
Ferri A., Casciati A., Celsi F., Rotilio G. and Carrì M. T. (2001) Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis. J. Neurochem. 79, 531-538.
-
(2001)
J. Neurochem.
, vol.79
, pp. 531-538
-
-
Ferri, A.1
Casciati, A.2
Celsi, F.3
Rotilio, G.4
Carrì, M.T.5
-
16
-
-
0345700751
-
Protein kinase and protein phosphatase expression in the central nervous system of G93A mSOD over-expressing mice
-
Hu J. H., Chernoff K., Pelech S. and Krieger C. (2003a) Protein kinase and protein phosphatase expression in the central nervous system of G93A mSOD over-expressing mice. J. Neurochem. 85, 422-431.
-
(2003)
J. Neurochem.
, vol.85
, pp. 422-431
-
-
Hu, J.H.1
Chernoff, K.2
Pelech, S.3
Krieger, C.4
-
17
-
-
0345184327
-
Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord
-
Hu J. H., Zhang H., Wagey R., Krieger C. and Pelech S. L. (2003b) Protein kinase and protein phosphatase expression in amyotrophic lateral sclerosis spinal cord. J. Neurochem. 85, 432-442.
-
(2003)
J. Neurochem.
, vol.85
, pp. 432-442
-
-
Hu, J.H.1
Zhang, H.2
Wagey, R.3
Krieger, C.4
Pelech, S.L.5
-
18
-
-
0020565637
-
Protein phosphatases: Properties and role in cellular regulation
-
Ingebritsen T. S. and Cohen P. (1983) Protein phosphatases: properties and role in cellular regulation. Science 221, 331-337.
-
(1983)
Science
, vol.221
, pp. 331-337
-
-
Ingebritsen, T.S.1
Cohen, P.2
-
19
-
-
0032926745
-
Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons
-
Koh J. Y., Kim D. K., Hwang J. Y., Kim Y. H. and Seo J. H. (1999) Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons. J. Neurochem. 72, 716-723.
-
(1999)
J. Neurochem.
, vol.72
, pp. 716-723
-
-
Koh, J.Y.1
Kim, D.K.2
Hwang, J.Y.3
Kim, Y.H.4
Seo, J.H.5
-
20
-
-
0029798880
-
Reduction of calcineurin enzymatic activity in Alzheimer's disease: Correlation with neuropathologic changes
-
Ladner C. J., Czech J., Maurice J., Lorens S. A. and Lee J. M. (1996) Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes. J. Neuropathol. Exp. Neurol. 55, 924-931.
-
(1996)
J. Neuropathol. Exp. Neurol.
, vol.55
, pp. 924-931
-
-
Ladner, C.J.1
Czech, J.2
Maurice, J.3
Lorens, S.A.4
Lee, J.M.5
-
21
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
23
-
-
0030825472
-
Therapeutic advances in amyotrophic lateral sclerosis
-
Louvel E., Hugon J. and Doble A. (1997) Therapeutic advances in amyotrophic lateral sclerosis. Trends Pharmacol. Sci. 18, 196-203.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 196-203
-
-
Louvel, E.1
Hugon, J.2
Doble, A.3
-
24
-
-
0030961492
-
Evidence for colocalization of calcineurin and calcium channels in dorsal root ganglion neurons
-
Lukyanetz E. A. (1997) Evidence for colocalization of calcineurin and calcium channels in dorsal root ganglion neurons. Neurosci. 78, 625-628.
-
(1997)
Neurosci.
, vol.78
, pp. 625-628
-
-
Lukyanetz, E.A.1
-
25
-
-
0032941253
-
Potential role of calcineurin for brain ischemia and traumatic injury
-
Morioka M., Hamada J.-I., Ushio Y. and Miyamoto E. (1999) Potential role of calcineurin for brain ischemia and traumatic injury. Prog. Neurobiol. 58, 1-30.
-
(1999)
Prog. Neurobiol.
, vol.58
, pp. 1-30
-
-
Morioka, M.1
Hamada, J.-I.2
Ushio, Y.3
Miyamoto, E.4
-
26
-
-
0037332066
-
The efficacy of trientine or ascorbate alone compared to that of the combined treatment with these two agents in familial amyotrophic lateral sclerosis model mice
-
Nagano S., Fujii Y., Yamamoto T., Taniyama M., Fukada K., Yanagihara T. and Sakoda S. (2003) The efficacy of trientine or ascorbate alone compared to that of the combined treatment with these two agents in familial amyotrophic lateral sclerosis model mice. Exp Neurol. 179, 176-180.
-
(2003)
Exp. Neurol.
, vol.179
, pp. 176-180
-
-
Nagano, S.1
Fujii, Y.2
Yamamoto, T.3
Taniyama, M.4
Fukada, K.5
Yanagihara, T.6
Sakoda, S.7
-
27
-
-
0037155226
-
Redox control of calcineurin by targeting the binuclear Fe (2+)-Zn (2+) center at the enzyme active site
-
Namgaladze D., Hofer H. W. and Ullrich V. (2002) Redox control of calcineurin by targeting the binuclear Fe (2+)-Zn (2+) center at the enzyme active site. J. Biol. Chem. 277, 5962-5969.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5962-5969
-
-
Namgaladze, D.1
Hofer, H.W.2
Ullrich, V.3
-
28
-
-
0027934706
-
Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate
-
Nicols R. A., Suplick G. R. and Brown J. M. (1994) Calcineurin-mediated protein dephosphorylation in brain nerve terminals regulates the release of glutamate. J. Biol. Chem. 269, 23817-23823.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23817-23823
-
-
Nicols, R.A.1
Suplick, G.R.2
Brown, J.M.3
-
29
-
-
0030069916
-
Postsynaptic mechanisms for bidirectional control of MAP2 phosphorylation by gluthamate receptors
-
Quinland E. M. and Halpain S. (1996) Postsynaptic mechanisms for bidirectional control of MAP2 phosphorylation by gluthamate receptors. Neuron 16, 357-368.
-
(1996)
Neuron
, vol.16
, pp. 357-368
-
-
Quinland, E.M.1
Halpain, S.2
-
30
-
-
0032827346
-
Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
Reinholz M. M., Merkle C. M. and Poduslo J. F. (1999) Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis. Exp Neurol. 159, 204-216.
-
(1999)
Exp. Neurol.
, vol.159
, pp. 204-216
-
-
Reinholz, M.M.1
Merkle, C.M.2
Poduslo, J.F.3
-
31
-
-
0035171622
-
A novel calcineurin splice variant that modifies calcineurin activity
-
Reuter A., Mi J., Sehrsam I., Ludolph A. C. and Volkel H. (2001) A novel calcineurin splice variant that modifies calcineurin activity. Eur. J. Biochem. 268, 5955-5960.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 5955-5960
-
-
Reuter, A.1
Mi, J.2
Sehrsam, I.3
Ludolph, A.C.4
Volkel, H.5
-
32
-
-
0033779701
-
Calcineurin: Form and function
-
Rusnak F. and Mertz P. (2000) Calcineurin: form and function. Physiol. Rev. 80, 1483-1521.
-
(2000)
Physiol. Rev.
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
33
-
-
0028971035
-
2+-activated cell death in mammalian cells
-
2+-activated cell death in mammalian cells. J. Cell Biol. 131, 735-743.
-
(1995)
J. Cell Biol.
, vol.131
, pp. 735-743
-
-
Shibasaki, F.1
McKeon, F.2
-
34
-
-
0033588530
-
Calcium-containing endosomes at oculomotor terminals in animal models of ALS
-
Siklos L., Engelhardt J. I., Adalbert R. and Appel S. H. (1999) Calcium-containing endosomes at oculomotor terminals in animal models of ALS. Neuroreport. 10, 2539-2545.
-
(1999)
Neuroreport
, vol.10
, pp. 2539-2545
-
-
Siklos, L.1
Engelhardt, J.I.2
Adalbert, R.3
Appel, S.H.4
-
35
-
-
0033777816
-
Protective effects of riluzole on dopamine neurons: Involvement of oxidative stress and cellular energy metabolism
-
Storch A., Burkhardt K., Ludolph A. C. and Schwarz J. (2000) Protective effects of riluzole on dopamine neurons: involvement of oxidative stress and cellular energy metabolism. J. Neurochem. 75, 2259-2269.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2259-2269
-
-
Storch, A.1
Burkhardt, K.2
Ludolph, A.C.3
Schwarz, J.4
-
36
-
-
0028929331
-
Synaptic desensitization of NMDA receptors by calcineurin
-
Tong G., Shepherd D. and Jahr C. E. (1995) Synaptic desensitization of NMDA receptors by calcineurin. Science 267, 1510-1512.
-
(1995)
Science
, vol.267
, pp. 1510-1512
-
-
Tong, G.1
Shepherd, D.2
Jahr, C.E.3
-
37
-
-
0037111503
-
Do oxidatively modified proteins cause ALS?
-
Valentine J. S. (2002) Do oxidatively modified proteins cause ALS? Free Radic. Biol. Med. 33, 1314-1320.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1314-1320
-
-
Valentine, J.S.1
-
38
-
-
0035902968
-
Superoxide dismutase mutations of familial amyotrophic lateral sclerosis and the oxidative inactivation of calcineurin
-
Volkel H., Scholz M., Link J., Selzle M., Werner P., Tunnemann R., Jung G., Ludolph A. C. and Reuter A. (2001) Superoxide dismutase mutations of familial amyotrophic lateral sclerosis and the oxidative inactivation of calcineurin. FEBS Lett. 503, 201-205.
-
(2001)
FEBS Lett.
, vol.503
, pp. 201-205
-
-
Volkel, H.1
Scholz, M.2
Link, J.3
Selzle, M.4
Werner, P.5
Tunnemann, R.6
Jung, G.7
Ludolph, A.C.8
Reuter, A.9
-
39
-
-
0029759409
-
Superoxide dismutase protects calcineurin from inactivation
-
Wang X., Culotta V. C. and Klee C. B. (1996) Superoxide dismutase protects calcineurin from inactivation. Nature 383, 434-437.
-
(1996)
Nature
, vol.383
, pp. 434-437
-
-
Wang, X.1
Culotta, V.C.2
Klee, C.B.3
-
40
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang H. G., Pathan N., Ethell I. M., Krajewski S., Yamaguchi Y., Shibasaki F., McKeon F., Bobo T., Franke T. F. and Reed J. C. (1999) Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science 284, 339-343.
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
41
-
-
0030887172
-
Calcineurin regulation of synaptic function: From ion channels to transmitter release and gene transcription
-
Yakel J. L. (1997) Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription. Trends Pharmacol. Sci. 18, 124-134.
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 124-134
-
-
Yakel, J.L.1
-
42
-
-
0030764597
-
Calcineurin modulates G protein-mediated inhibition of N-type calcium channels in rat sympthatetic neurons
-
Zhu Y. and Yakel J. L. (1997) Calcineurin modulates G protein-mediated inhibition of N-type calcium channels in rat sympthatetic neurons. J. Neurophisiol. 78, 1161-1165.
-
(1997)
J. Neurophisiol.
, vol.78
, pp. 1161-1165
-
-
Zhu, Y.1
Yakel, J.L.2
|