Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis

Journal of Neurochemistry

Volumn 79, Issue 3, 2001, Pages 531-538

  Ferri, Alberto ^a   Gabbianelli, Roberta ^a,d   Casciati, Arianna ^c   Celsi, Fulvio ^b   Rotilio, Giuseppe ^b   Carrì, Maria Teresa ^b,c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c Centro di Neurobiologia Sperimentale 'Mondino Tor Vergata S Lucia'   (Italy)

^d ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Calcineurin; Familial amyotrophic lateral sclerosis; Neurodegeneration; Reactive oxygen species, redox regulation; Superoxide dismutase

Indexed keywords

CALCINEURIN; COPPER ZINC SUPEROXIDE DISMUTASE; PROTEIN SERINE THREONINE KINASE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME MECHANISM; FAMILIAL DISEASE; IN VITRO STUDY; NERVE DEGENERATION; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; OXIDATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION;

AEROBIOSIS; AMYOTROPHIC LATERAL SCLEROSIS; ANTIOXIDANTS; ASCORBIC ACID; CALCINEURIN; CALCIUM; COPPER; DITHIOTHREITOL; ENZYME ACTIVATION; HUMANS; NERVE DEGENERATION; OXIDATION-REDUCTION; POINT MUTATION; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 0034763797     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00558.x     Document Type: Article

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