Long-term cadmium exposure accelerates age-related mitochondrial changes in renal epithelial cells

Toxicology

Volumn 203, Issue 1-3, 2004, Pages 145-154

  Takaki, Aya ^a   Jimi, Shiro ^a   Segawa, Masaru ^a   Hisano, Satoshi ^a   Takebayashi, Shigeo ^b   Iwasaki, Hiroshi ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b NONE

Author keywords

Chronic cadmium intoxication; Itai Itai disease; Mitochondrial DNA deletion; Proximal tubule

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; CYTOCHROME C; DNA; PHOSPHATIDYLCHOLINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CELL FRACTIONATION; ENZYME ACTIVITY; FEMALE; KIDNEY CELL; KIDNEY CORTEX; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PRIORITY JOURNAL; RAT; TIME;

ADENOSINE TRIPHOSPHATE; AGING; ANIMALS; CADMIUM POISONING; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; KIDNEY CORTEX; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIA; OXIDATION-REDUCTION; PHOSPHATIDYLCHOLINES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 4444363857     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.06.005     Document Type: Article

References (41)

1. Adams R.G., Harrison J.F., Scott P. The development of cadmium-induced proteinuria, impaired renal function, and osteomalacia in alkaline battery workers. Q. J. Med. 38:1969;425-443
2. Barazzoni R., Short K.R., Nair K.S. Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J. Biol. Chem. 275:2000;3343-3347
3. Britton R.S. Metal-induced hepatotoxicity. Semin. Liver Dis. 16:1996;3-12
4. Buchet J.P., Lauwerys R., Roels H., Bernard A., Bruaux P., Claeys F., Ducoffre G., de Plaen P., Staessen J., Amery A., et al. Renal effects of cadmium body burden of the general population. Lancet. 336:1990;699-702
5. Corral-Debrinski M., Horton T., Lott M.T., Shoffner J.M., Beal M.F., Wallace D.C. Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age. Nat. Genet. 2:1992;324-329
6. Edris W., Burgett B., Stine O.C., Filburn C.R. Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA. Mutat. Res. 316:1994;69-78
7. Filburn C.R., Edris W., Tamatani M., Hogue B., Kudryashova I., Hansford R.G. Mitochondrial electron transport chain activities and DNA deletions in regions of the rat brain. Mech. Ageing Dev. 87:1996;35-46
8. Filser N., Margue C., Richter C. Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs. Biochem. Biophys. Res. Commun. 233:1997;102-107
9. Friberg L. Cadmium and the kidney. Environ. Health Persp. 54:1984;1-11
10. Gadaleta M.N., Rainaldi G., Lezza A.M., Milella F., Fracasso F., Cantatore P. Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats. Mutat. Res. 275:1992;181-193
11. Hayakawa M., Hattori K., Sugiyama S., Ozawa T. Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem. Biophys. Res. Commun. 189:1992;979-985
12. Holt I.J., Harding A.E., Morgan-Hughes J.A. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature. 331:1988;717-719
13. Itabe H., Yamamoto H., Suzuki M., Kawai Y., Nakagawa Y., Suzuki A., Imanaka T., Takano T. Oxidized phosphatidylcholines that modify proteins. Analysis by monoclonal antibody against oxidized low density lipoprotein. J. Biol. Chem. 271:1996;33208-33217
14. Itokawa Y., Abe T., Tabei R., Tanaka S. Renal and skeletal lesions in experimental cadmium poisoning: histological and biochemical approaches. Arch. Environ. Health. 28:1974;149-154
15. Jimi S., Uesugi N., Saku K., Itabe H., Zhang B., Arakawa K., Takebayashi S. Possible induction of renal dysfunction in patients with lecithin:cholesterol acyltransferase deficiency by oxidized phosphatidylcholine in glomeruli. Arterioscler. Thromb. Vasc. Biol. 19:1999;794-801
16. Johns D.R., Rutledge S.L., Stine O.C., Hurko O. Directly repeated sequences associated with pathogenic mitochondrial DNA deletions. Proc. Natl. Acad. Sci. U.S.A. 86:1989;8059-8062
17. Kajikawa K., Nakanishi I., Kuroda K. Morphological changes of the kidney and bone of rats in chronic cadmium poisoning. Exp. Mol. Pathol. 34:1981;9-24
18. Kakimoto M., Inoguchi T., Sonta T., Yu H.Y., Imamura M., Etoh T., Hashimoto T., Nawata H. Accumulation of 8-hydroxy-2′-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats. Diabetes. 51:2002;1588-1595
19. Lauwerys R.R., Bernard A.M. Cadmium and the kidney. Brit. J. Ind. Med. 43:1986;433-435
20. Lee H.C., Pang C.Y., Hsu H.S., Wei Y.H. Differential accumulations of 4977 bp deletion in mitochondrial DNA of various tissues in human ageing. Biochim. Biophys. Acta. 1226:1994;37-43
21. Liu S., Kawai K., Tyurin V.A., Tyurina Y.Y., Borisenko G.G., Fabisiak J.P., Quinn P.J., Pitt B.R., Kagan V.E. Nitric oxide-dependent pro-oxidant and pro-apoptotic effect of metallothioneins in HL-60 cells challenged with cupric nitrilotriacetate. Biochem. J. 354:2001;397-406
22. Mecocci P., MacGarvey U., Kaufman A.E., Koontz D., Shoffner J.M., Wallace D.C., Beal M.F. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann. Neurol. 34:1993;609-616
23. Mitsumori K., Shibutani M., Sato S., Onodera H., Nakagawa J., Hayashi Y., Ando M. Relationship between the development of hepato-renal toxicity and cadmium accumulation in rats given minimum to large amounts of cadmium chloride in the long-term: preliminary study. Arch. Toxicol. 72:1998;545-552
24. Moraczewski A., Anderson R.C. The determination by quantitative histochemistry of the effect of phenothiazines on brain cytochrome c oxidase activity. J. Histochem. Cytochem. 14:1966;64-76
25. Munscher C., Rieger T., Muller-Hocker J., Kadenbach B. The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages. FEBS Lett. 317:1993;27-30
26. Naganuma A., Miura K., Tanaka-Kagawa T., Kitahara J., Seko Y., Toyoda H., Imura N. Overexpression of manganese-superoxide dismutase prevents methylmercury toxicity in HeLa cells. Life Sci. 62:1998;PL157-PL161
27. Nakada K., Inoue K., Ono T., Isobe K., Ogura A., Goto Y.I., Nonaka I., Hayashi J.I. Inter-mitochondrial complementation: mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat. Med. 7:2001;934-940
28. Niaudet P., Heidet L., Munnich A., Schmitz J., Bouissou F., Gubler M.C., Rotig A. Deletion of the mitochondrial DNA in a case of de Toni-Debre-Fanconi syndrome and Pearson syndrome. Pediatr. Nephrol. 8:1994;164-168
29. Nickander K.K., Schmelzer J.D., Low P.A. Assessment of the "common" 4.8-kb mitochondrial DNA deletion and identification of several closely related deletions in the dorsal root ganglion of aging and streptozotocin rats. J. Peripher. Nerv. Syst. 7:2002;96-103
30. Papa S., Skulachev V.P. Reactive oxygen species, mitochondria, apoptosis and aging. Mol. Cell. Biochem. 174:1997;305-319
31. Schon E.A., Rizzuto R., Moraes C.T., Nakase H., Zeviani M., DiMauro S. A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA. Science. 244:1989;346-349
32. Seaton T.A., Jenner P., Marsden C.D. Mitochondrial respiratory enzyme function and superoxide dismutase activity following brain glutathione depletion in the rat. Biochem. Pharmacol. 52:1996;1657-1663
33. Shigenaga M.K., Hagen T.M., Ames B.N. Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. U.S.A. 91:1994;10771-10778
34. Szabolcs M.J., Seigle R., Shanske S., Bonilla E., DiMauro S., D'Agati V. Mitochondrial DNA deletion: a cause of chronic tubulointerstitial nephropathy. Kidney Int. 45:1994;1388-1396
35. Takebayashi S., Jimi S., Segawa M., Kiyoshi Y. Cadmium induces osteomalacia mediated by proximal tubular atrophy and disturbances of phosphate reabsorption. A study of 11 autopsies. Pathol. Res. Pract. 196:2000;653-663
36. Tritschler H.J., Medori R. Mitochondrial DNA alterations as a source of human disorders. Neurology. 43:1993;280-288
37. Wallace D.C. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science. 256:1992;628-632
38. Yoshiki S., Yanagisawa T., Kimura M., Otaki N., Suzuki M. Bone and kidney lesions in experimental cadmium intoxication. Arch. Environ. Health. 30:1975;559-562
39. Yowe D.L., Ames B.N. Quantitation of age-related mitochondrial DNA deletions in rat tissues shows that their pattern of accumulation differs from that of humans. Gene. 209:1998;23-30
40. Zeviani M., Moraes C.T., DiMauro S., Nakase H., Bonilla E., Schon E.A., Rowland L.P. Deletions of mitochondrial DNA in Kearns-Sayre syndrome. Neurology. 38:1988;1339-1346
41. Zhang C., Bills M., Quigley A., Maxwell R.J., Linnane A.W., Nagley P. Varied prevalence of age-associated mitochondrial DNA deletions in different species and tissues: a comparison between human and rat. Biochem. Biophys. Res. Commun. 230:1997;630-635