Mechanisms of viral interference with MHC class I antigen processing and presentation

Annual Review of Cell and Developmental Biology

Volumn 15, Issue , 1999, Pages 579-606

  Yewdell, J W ^a   Bennink, J R ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Antigen processing; CTL; MHC; Virus

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS VECTOR;

ANTIGEN PRESENTATION; AUTOIMMUNITY; CELL FUNCTION; CELL SURFACE; CELL TRANSPORT; GENE THERAPY; IMMUNOREGULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

ANIMALS; ANTIGEN PRESENTATION; FORECASTING; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; VIRAL PHYSIOLOGY; VIRUSES;

VERTEBRATA;

EID: 0033280323     PISSN: 10810706     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.cellbio.15.1.579     Document Type: Review

References (87)

1. Human cytomegalovirus inhibits antigen presentation by a sequential multistep process
2. The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP
3. Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus protein ICP47
4. Reduced allorecognition of adenovirus-2 infected cells
5. Impaired intracellular transport of class I MHC antigens as a possible means for adenovirus to evade immune surveillance
6. Introduction of a glycosylation site into a secreted protein provides evidence for a novel antigen processing pathway: Transport of precursors of MHC class I resistricted-peptides from the endoplasmic reticulum to the cytosol
7. The proteasome: Paradigm of a self-compartmentalizing protease
8. Association of human class I MHC alleles with the adenovirus E3/19k protein
9. Structure of the viral TAP-inhibitor ICP47 induced by membrane association
10. Adenovirus E19 has two mechanisms for affecting class I MHC expression
11. Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing
12. Ubiquitin and the control of protein fate in the secretory and endocytic pathways
13. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens
14. The E3/19K protein of adenovirus type 2 binds to the domains of histocompatibility antigens required for CTL recognition
15. New COP1-binding motifs involved in ER retrieval
16. Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation
17. Antigen presentation requires transport of MHC class I molecules from the endoplasmic reticulum
18. Ligand recognition by alpha beta T cell receptors
19. Early region 3 of adenovirus type. 19 (subgroup D) encodes an HLA-binding protein distinct from that of subgroups B and C
20. Modulation of antigen processing and presentation by persistent virus infections and in tumors
21. Transporter associated with antigen processing
22. Novel proteins associated with MHC class I antigens in cells expressing the adenovirus protein E3/19k
23. Identification of class I MHC regions which bind to the adenovirus E3-19k protein
24. A viral inhibitor of peptide transporters for antigen presentation
25. Rapid degradation of CD4 in cells expressing HIV-1 Env and Vpu is blocked by proteasome inhibitors
26. 2-terminal 35 residues
27. Selective interference with class I major histocompatibility complex presentation of the major immediate-early protein following infection with human cytomegalovirus
28. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product
29. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
30. A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter
31. Herpes simplex virus turns off the TAP to evade host immunity
32. The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex
33. Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum
34. Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains
35. Inhibition of major histocompatibility complex class I antigen presentation in pig and primate cells by herpes simplex virus type 1 and 2 ICP47
36. Complex formation of class I transplantation antigens and a viral glycoprotein
37. The human immuno-deficiency virus type-1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of MHC class I molecules
38. Development and selection of T cells: Facts and puzzles
39. A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface
40. Herpes simplex virus inhibitor ICP47 destabilizes the transporter associated with antigen processing (TAP) heterodimer
41. NK cell receptors
42. Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules
43. The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation
44. Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1
45. Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1
46. 1991. Co-expression of the human HLA-B27 class I antigen and the E3/19K protein of adenovirus-2 in insect cells using a baculovirus vector
47. ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly
48. Interactions between HIV 1 Nef and vacuolar ATPase facilitate the internalization of CD4
49. The HCMV gene products US11 and US2 differ in their ability to attack allelic forms of murine major histocompatibilty complex (MHC) class I heavy chains
50. The three-dimensional structure of peptide-MHC complexes
51. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
52. Virus-encoded receptors for cytokines and chemokines
53. Escape of human immunodeficiency virus from immune control
54. Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules
55. Receptors for HLA class-I molecules in human natural killer cells
56. A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules
57. The class I antigen-processing pathway for the membrane protein tyrosinase involves translation in the endoplasmic reticulum and processing in the cytosol
58. Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum
59. Nef-an adaptor adaptor?
60. The association with class-I transplantation antigens and an adenovirus membrane protein
61. Association between transplantation antigens and a viral membrane protein synthesized from a mammalian expression vector
62. Structural and functional dissection of an MHC class I antigen-binding adenovirus glycoprotein
63. Mechanisms of MHC class I-restricted antigen processing
64. HIV nef: The mother of all evil?
65. MHC ligands and peptide motifs: First listing
66. A cytomegalovirus glycoprotein re-routes MHC class I complexes to lysosomes for degradation
67. Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression
68. CD4 glycoprotein degradation induced by human immunodeficiency virus type 1 Vpu protein requires the function of proteasomes and the ubiquitin-conjugating pathway
69. The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains
70. Trophoblast class I major histocompatibility complex (MHC) products are resistant to rapid degradation imposed by the human cytomegalovirus (HCMV) gene products US2 and US11
71. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 nef protein
72. Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens
73. Abrogation of cell surface expression of human class I transplantation antigens by an adenovirus protein in Xenopus laevis oocytes
74. An adenovirus glycoprotein binds heavy chains of class I transplantation antigens from man and mouse
75. Suppression of MHC class I antigen presentation by human adenoviruses
76. One step ahead of the game: Viral immunoregulatory molecules
77. T lymphocyte tolerance: From thymic deletion to peripheral control mechanisms
78. The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression
79. Intracellular location, complex formation, function of the transporter associated with antigen processing in yeast
80. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
81. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
82. Cell biology of antigen processing and presentation to MHC class I molecule-restricted T lymphocytes
83. Immunodominance in MHC Class I restricted responses
84. + T cell responses to infectious agents, tumors, transplants, vaccines
85. Antigen processing and presentation by the class I major histocompatibility complex
86. A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes
87. A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments