Matrix metalloproteinase-26 (Matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer

Gynecologic Oncology

Volumn 94, Issue 3, 2004, Pages 661-670

  Pilka, R ^a,b   Norata, G D ^c   Domanski, H ^a   Andersson, C ^a   Hansson, S ^a   Eriksson, P ^c   Casslen B ^a,d  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d Biomedical Centre C 14   (Sweden)

Author keywords

Endometrial carcinoma; Estrogen receptor; mRNA; Proteinase; Regulation

Indexed keywords

ESTROGEN RECEPTOR ALPHA; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 26; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SEQUENCE; ARTICLE; BLOOD VESSEL WALL; CANCER STAGING; CONTROLLED STUDY; DOWN REGULATION; ENDOMETRIUM; ENDOMETRIUM CANCER; ENDOMETRIUM HYPERPLASIA; EPITHELIUM; ESTROGEN RESPONSIVE ELEMENT; FEMALE; GENE CONTROL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MENSTRUAL CYCLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; STROMA; TUMOR CELL; TUMOR DIFFERENTIATION;

ADULT; AGED; AGED, 80 AND OVER; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; ENDOMETRIAL HYPERPLASIA; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; IN SITU HYBRIDIZATION; MATRIX METALLOPROTEINASES; MATRIX METALLOPROTEINASES, SECRETED; MIDDLE AGED; PRECANCEROUS CONDITIONS; RNA, MESSENGER;

EID: 4444276289     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ygyno.2004.05.024     Document Type: Article

References (53)

1. McCawley L.J., Matrisian L.M. Matrix metalloproteinases: they're not just for matrix anymore! Curr. Opin. Cell Biol. 13(5):2001;534-540
2. Egeblad M., Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev., Cancer. 2(3):2002;161-174
3. Liotta L.A., Tryggvason K., Garbisa S., Hart I., Foltz C.M., Shafie S. Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature. 284(5751):1980;67-68
4. Nabeshima K., Lane W.S., Biswas C. Partial sequencing and characterization of the tumor cell-derived collagenase stimulatory factor. Arch. Biochem. Biophys. 285(1):1991;90-96
5. Sternlicht M.D., Lochter A., Sympson C.J., Huey B., Rougier J.P., Gray J.W., et al. The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell. 98(2):1999;137-146
6. Overall C.M., Lopez-Otin C. Strategies for MMP inhibition in cancer: innovations for the post-trial era. Nat. Rev., Cancer. 2(9):2002;657-672
7. Chambers A.F., Matrisian L.M. Changing views of the role of matrix metalloproteinases in metastasis. J. Natl. Cancer Inst. 89(17):1997;1260-1270
8. Noe V., Fingleton B., Jacobs K., Crawford H.C., Vermeulen S., Steelant W., et al. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1. J. Cell Sci. 114(Pt. 1):2001;111-118
9. Basset P., Bellocq J.P., Wolf C., Stoll I., Hutin P., Limacher J.M., et al. A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature. 348(6303):1990;699-704
10. Nelson A.R., Fingleton B., Rothenberg M.L., Matrisian L.M. Matrix metalloproteinases: biologic activity and clinical implications. J. Clin. Oncol. 18(5):2000;1135-1149
11. Knox J.D., Wolf C., McDaniel K., Clark V., Loriot M., Bowden G.T., et al. Matrilysin expression in human prostate carcinoma. Mol. Carcinog. 15(1):1996;57-63
12. McDonnell S., Navre M., Coffey R.J. Jr., Matrisian L.M. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol. Carcinog. 4(6):1991;527-533
13. Rodgers W.H., Osteen K.G., Matrisian L.M., Navre M., Giudice L.C., Gorstein F. Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle. Am. J. Obstet. Gynecol. 168(1 Pt. 1):1993;253-260
14. Ueno H., Yamashita K., Azumano I., Inoue M., Okada Y. Enhanced production and activation of matrix metalloproteinase-7 (matrilysin) in human endometrial carcinomas. Int. J. Cancer. 84(5):1999;470-477
15. Yamashita K., Azumano I., Mai M., Okada Y. Expression and tissue localization of matrix metalloproteinase 7 (matrilysin) in human gastric carcinomas. Implications for vessel invasion and metastasis. Int. J. Cancer. 79(2):1998;187-194
16. Silverberg S.G., Kurman R.J. Endometrial polyps and hyperplasia. Third ed.:1992;AFIP, Washington (DC)
17. Mencaglia L. Hysteroscopy and adenocarcinoma. Obstet. Gynecol. Clin. North Am. 22(3):1995;573-579
18. Wikland M., Granberg S., Karlsson B. Replacing diagnostic curettage by vaginal ultrasound. Eur. J. Obstet. Gynecol. Reprod. Biol. 49(1-2):1993;35-38
19. American Cancer Society Cancer facts figures, 1995. 1995;American Cancer Society, Atlanta
20. Creasman W.T. New gynecologic cancer staging. Obstet. Gynecol. 75(2):1990;287-288
21. de Coignac A.B., Elson G., Delneste Y., Magistrelli G., Jeannin P., Aubry J.P., et al. Cloning of MMP-26. A novel matrilysin-like proteinase. Eur. J. Biochem. 267(11):2000;3323-3329
22. Marchenko G.N., Ratnikov B.I., Rozanov D.V., Godzik A., Deryugina E.I., Strongin A.Y. Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin. Biochem. J. 356(Pt. 3):2001;705-718
23. Park H.I., Ni J., Gerkema F.E., Liu D., Belozerov V.E., Sang Q.X. Identification and characterization of human endometase (Matrix metalloproteinase-26) from endometrial tumor. J. Biol. Chem. 275(27):2000;20540-20544
24. Uria J.A., Lopez-Otin C. Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity. Cancer Res. 60(17):2000;4745-4751
25. Pilka R., Whatling C., Domanski H., Hansson S., Eriksson P., Casslen B. Epithelial expression of matrix metalloproteinase-26 (MMP-26) is elevated at midcycle in the human endometrium. Mol. Hum. Reprod. 9(5):2003;271-277
26. Hendrickson M.R., Kempson R.L. Surgical pathology of the uterine corpus. 1980;Saunders, Philadelphia
27. Noyes R.W., Hertig A.T., Rock J. Dating the endometrial biopsy. Fertil. Steril. 1:1950;3-25
28. Young W.S. In situ hybridization histochemistry. Björklund A., Hökfelt T., Wouterlood F.G., van den Pol A.N. Handbook of chemical neuroanatomy: analysis of neuronal microcircuits and synaptic interactions. 1990;481-512 Elsevier Science Publishers B.V., Amsterdam
29. Cox K.H., DeLeon D.V., Angerer L.M., Angerer R.C. Detection of mRNA in sea urchin embryos by in situ hybridization using asymmetric RNA probes. Dev. Biol. 101:1984;485-502
30. Whitfield H.J., Brady L.S., Smith M.A., Mamalaki E., Fox R.J., Herkenham M. Optimization of cRNA probe in situ hybridization methodology for localization of glucocorticoid receptor mRNA in rat brain: a detailed protocol. Cell. Mol. Neurobiol. 10:1990;145-157
31. Shi S.R., Key M.E., Kalra K.L. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J. Histochem. Cytochem. 39(6):1991;741-748
32. Zhang J., Cao Y.J., Zhao Y.G., Sang Q.X., Duan E.K. Expression of matrix metalloproteinase-26 and tissue inhibitor of metalloproteinase-4 in human normal cytotrophoblast cells and a choriocarcinoma cell line, JEG-3. Mol. Hum. Reprod. 8(7):2002;659-666
33. Isaka K., Nishi H., Nakai H., Nakada T., Feng Li Y., Ebihara Y., et al. Matrix metalloproteinase-26 is expressed in human endometrium but not in endometrial carcinoma. Cancer. 97(1):2003;79-89
34. Tunuguntla R., Ripley D., Sang Q.X., Chegini N. Expression of matrix metalloproteinase-26 and tissue inhibitors of metalloproteinases TIMP-3 and-4 in benign endometrium and endometrial cancer small star, filled. Gynecol. Oncol. 89(3):2003;453-459
35. Di Nezza L.A., Misajon A., Zhang J., Jobling T., Quinn M.A., Ostor A.G., et al. Presence of active gelatinases in endometrial carcinoma and correlation of matrix metalloproteinase expression with increasing tumor grade and invasion. Cancer. 94(5):2002;1466-1475
36. Iurlaro M., Loverro G., Vacca A., Cormio G., Ribatti D., Minischetti M., et al. Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with upgrading and myometrial invasion in endometrial carcinoma. Eur. J. Clin. Invest. 29(9):1999;793-801
37. Maatta M., Soini Y., Liakka A., Autio-Harmainen H. Localization of MT1-MMP, TIMP-1, TIMP-2, and TIMP-3 messenger RNA in normal, hyperplastic, and neoplastic endometrium. Enhanced expression by endometrial adenocarcinomas is associated with low differentiation. Am. J. Clin. Pathol. 114(3):2000;402-411
38. Sakamoto H., Kinoshita K., Nakayama Y., Takami T., Ohtani K., Izuka S., et al. Gene expression in primary, metastatic and recurrent lesions of endometrial cancer. Gynecol. Obstet. Invest. 48(3):1999;215-220
39. Gompel C., Silverberg S.G. Endometrial hyperplasia. Fourth ed.:1994;J.B. Lippincott, Philadelphia
40. Mertens H.J., Heineman M.J., Theunissen P.H., de Jong F.H., Evers J.L. Androgen, estrogen and progesterone receptor expression in the human uterus during the menstrual cycle. Eur. J. Obstet. Gynecol. Reprod. Biol. 98(1):2001;58-65
41. Lecce G., Meduri G., Ancelin M., Bergeron C., Perrot-Applanat M. Presence of estrogen receptor beta in the human endometrium through the cycle: expression in glandular, stromal, and vascular cells. J. Clin. Endocrinol. Metab. 86(3):2001;1379-1386
42. Utsunomiya H., Suzuki T., Harada N., Ito K., Matsuzaki S., Konno R., et al. Analysis of estrogen receptor alpha and beta in endometrial carcinomas: correlation with ER beta and clinicopathologic findings in 45 cases. Int. J. Gynecol. Pathol. 19(4):2000;335-341
43. Punnonen R., Mattila J., Kuoppala T., Koivula T. DNA ploidy, cell proliferation and steroid hormone receptors in endometrial hyperplasia and early adenocarcinoma. J. Cancer Res. Clin. Oncol. 119(7):1993;426-429
44. Kounelis S., Kapranos N., Kouri E., Coppola D., Papadaki H., Jones M.W. Immunohistochemical profile of endometrial adenocarcinoma: a study of 61 cases and review of the literature. Mod. Pathol. 13(4):2000;379-388
45. Kato K., Horiuchi S., Terao Y., Ueoka Y., Nishida J., Mori D., et al. Relevance of ER to the development of endometrial hyperplasia and adenocarcinoma. Breast Cancer. 6(4):1999;312-319
46. Driscoll M.D., Sathya G., Muyan M., Klinge C.M., Hilf R., Bambara R.A. Sequence requirements for estrogen receptor binding to estrogen response elements. J. Biol. Chem. 273(45):1998;29321-29330
47. Marchenko G.N., Marchenko N.D., Leng J., Strongin A.Y. Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin. Biochem. J. 363(Pt. 2):2002;253-262
48. Slater E.P., Redeuihl G., Theis K., Suske G., Beato M. The uteroglobin promoter contains a noncanonical estrogen responsive element. Mol. Endocrinol. 4(4):1990;604-610
49. Shaulian E., Karin M. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4(5):2002;E131-E136
50. Salmi A., Heikkila P., Lintula S., Rutanen E.M. Cellular localization of c-jun messenger ribonucleic acid and protein and their relation to the proliferation marker Ki-67 in the human endometrium. J. Clin. Endocrinol. Metab. 83(5):1998;1788-1796
51. Sang Q.X., Birkedal-Hansen H., Van Wart H.E. Proteolytic and non-proteolytic activation of human neutrophil progelatinase B. Biochim. Biophys. Acta. 1251(2):1995;99-108
52. Zhao Y.G., Xiao A.Z., Newcomer R.G., Park H.I., Kang T., Chung L.W., et al. Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells. J. Biol. Chem. 278(17):2003;15056-15064
53. Ramos-DeSimone N., Hahn-Dantona E., Sipley J., Nagase H., French D.L., Quigley J.P. Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. J. Biol. Chem. 274(19):1999;13066-13076