Design and synthesis of 3′-ureidoadenosine-5′-uronamides: Effects of the 3′-ureido group on binding to the A 3 adenosine receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 19, 2004, Pages 4851-4854

  Jeong, Lak Shin ^a   Kim, Myong Jung ^b   Kim, Hea Ok ^a,c   Gao, Zhan Guo ^c   Kim, Soo Kyung ^c   Jacobson, Kenneth A ^c   Chun, Moon Woo ^b  

^a University of Seoul   (South Korea)

^b Seoul National University   (South Korea)

^c Natl Inst Diabet Digest K   (United States)

Author keywords

3 Ureidoadenosine derivatives; A 3 adenosine receptor; Binding affinity; Hydrogen bonding donor; Steric effects

Indexed keywords

ADENOSINE A3 RECEPTOR; ADENOSINE DERIVATIVE; NUCLEOSIDE DERIVATIVE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYDROGEN BOND; NONHUMAN;

ADENOSINE; BINDING SITES; DRUG DESIGN; HYDROGEN BONDING; RECEPTOR, ADENOSINE A3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4444254918     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.07.042     Document Type: Article

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