Neuroimaging of declarative memory in schizophrenia

Scandinavian Journal of Psychology

Volumn 42, Issue 3, 2001, Pages 239-250

  Weiss, Anthony P ^a   Heckers, Stephan ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Memory; Neuroimaging; Schizophrenia

Indexed keywords

CEREBELLUM; HIPPOCAMPUS; HUMAN; MEMORY; MEMORY DISORDER; METHODOLOGY; NERVE CELL NETWORK; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PSYCHOLOGY; REVIEW; SCHIZOPHRENIA; SCINTISCANNING; THALAMUS;

CEREBELLUM; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MEMORY; MEMORY DISORDERS; NERVE NET; NEUROPSYCHOLOGICAL TESTS; PREFRONTAL CORTEX; RADIONUCLIDE IMAGING; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; THALAMUS;

EID: 0035407942     PISSN: 00365564     EISSN: None     Source Type: Journal    
DOI: 10.1111/1467-9450.00234     Document Type: Article

References (109)

1. Aggleton, J. P. (1997). The relationships between temporal lobe and diencephalic structures implicated in anterograde amnesia. Memory, 5, 49-71.
2. Aleman, A., Hijman, R., de Haan, E. H. F. & Kahn, R. S. (1999). Memory impairment in schizophrenia: a meta-analysis. American Journal of Psychiatry, 156, 1358-1366.
3. Andreasen, N., Nasrallah, H. A., Dunn, V., Olson, S. C., Grove, W. M. & Ehrhardt, J. C. (1986). Structural abnormalities in the frontal system in schizophrenia. Archives of General Psychiatry, 43, 136-144.
4. Andreasen, N. C., Nopoulos, P., O'Leary, D. S., Miller, D. D., Wassink, T. & Flaum, M. (1999). Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms. Biological Psychiatry, 46, 908-920.
5. Andreasen, N. C., O'Leary, D. S., Cizadlo, T., Arndt, S., Rezai, K., Ponto, L. L. B., Watkins, G. L. & Hichwa, R. D. (1996). Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry. Proceedings of the National Association of Science USA, 93, 9985-9990.
6. Baare, W. F. C., Pol, H. E. H., Hijman, R., Mali, W. P. T., Viergever, M. A. & Kahn, R. S. (1999). Volumetric analysis of frontal lobe regions in schizophrenia: relation to cognitive function and symptomatology. Biological Psychiatry, 45, 1597-1605.
7. Bilder, R. M., Bogerts, B., Ashtari, M., Wu, H., Alvir, J. M., Jody, D., Reiter, G., Bell, L. & Lieberman, J. A. (1995). Anterior hippocampal volume reductions predict frontal lobe dysfunction in first episode schizophrenia. Schizophrenia Research, 17,47-58.
8. Blackwood, D. H. R., Glabus, M. F., Dunan, J., O'Carroll, R. E., Muir, W. J. & Ebmeier, K. P. (1999). Altered cerebral perfusion measured by SPECT in relatives of patients with schizophrenia. British Journal of Psychiatry, 175, 357-366.
9. Brebion, G., Amador, X., Smith, M. J. & Gorman, J. M. (1997). Mechanisms underlying memory impairment in schizophrenia. Psychological Medicine, 27, 383-393.
10. Buckner, R. L. & Koutsaal, W. (1998). Functional neuroimaging studies of encoding, priming, and explicit memory retrieval. Proceedings of the National Association of Science USA, 95, 891-898.
11. 99mTc-HMPAO single photon emission tomography (SPET) study. Psychological Medicine, 24, 463-472.
12. Busatto, G. F., David, A. S., Costa, D. C., Ell, P. J., Pilowsky, L. S., Lucey, J. V. & Kerwin, R. W. (1995). Schizophrenic auditory hallucinations are associated with increased regional cerebral blood flow during verbal memory activation in a study using single photon emission computed tomography. Psychiatry Research: Neuroimaging, 61, 255-264.
13. Carpenter, W. T., Arango, C., Buchanan, R. W. & Kirkpatrick, B. (1999). Deficit psychopathology and a paradigm shift in schizophrenia research. Biological Psychiatry, 46, 352-360.
14. Carpenter, W. T., Heinrichs, D. W. & Wagman, A. M. I. (1988). Deficit and nondeficit forms of schizophrenia: the concept. American Journal of Psychiatry, 145, 578-583.
15. Chua, S. E. & McKenna, P. J. (1995). Schizophrenia - a brain disease? A critical review of structural and functional cerebral abnormality in the disorder. British Journal of Psychiatry, 166, 563-582.
16. Clare, L., McKenna, P. J., Mortimer, A. M. & Baddeley, A. D. (1993). Memory in schizophrenia: what is impaired and what is preserved? Neuropsychologia, 31, 1225-1241.
17. Colombo, C., Abbruzzese, M., Livian, S., Scotti, G., Locatelli, M., Bonfanti, A. & Scarone, S. (1993). Memory functions and temporal-limbic morphology in schizophrenia. Psychiatry Research-Neuroimaging, 50, 45-56.
18. Crespo-Facorro, B., Paradiso, S., Andreasen, N. C., O'Leary, D. S., Watkins, G. L., Ponto, L. L. B. & Hichwa, R. D. (1999). Recalling word lists reveals " cognitive dysmetria" in schizophrenia: a positron emission tomography study. American Journal of Psychiatry, 156, 386-392.
19. DeLisi, L. E., Hoff, A. L., Schwartz, J. E., Shields, G. W., Halthore, S. N., Gupta, S. M., Henn, F. A. & Anand, A. K. (1991). Brain morphology in first-episode schizophrenia-like psychotic patients: a quantitative magnetic resonance imaging study. Biological Psychiatry, 29, 159-175.
20. Dusoir, H., Kapur, N., Byrnes, D. P., McKinstry, S. & Hoare, R. D. (1990). The role of diencephalic pathology in human memory disorder. Evidence from a penetrating paranasal brain injury. Brain 113, 1695-706.
21. Fleteher, P. C. (1998). The missing link: a failure of frontohippocampal integration in schizophrenia. Nature Neuroscience, 1, 266-267.
22. Fleteher, P. C., Frith, C. D. & Rugg, M. D. (1997). The functional neuroanatomy of episodic memory. Trends in Neuroscience, 20, 213-218.
23. Fletcher, P. C., McKenna, P. J., Frith, C. D., Grasby, P. M., Friston, K. J. & Dolan, R. J. (1998). Brain activations in schizophrenia during a graded memory task studied with functional neuroimaging. Archives of General Psychiatry, 55, 1001-1008.
24. Gabrielli, J. D. E., Poldrack, R. A. & Desmond, J. E. (1998). The role of the left prefrontal cortex in language and memory. Proceedings of the National Association of Science USA, 95, 906-913.
25. Ganguli, R., Carter, C., Mintun, M., Brar, J., Becker, J., Sarma, R., Nichols, T. & Bennington E. (1997). PET brain mapping study of auditory verbal supraspan memory versus visual fixation in schizophrenia. Biological Psychiatry, 41, 33-42.
26. Ganguli, R., Mintun, M. A., Becker, J. T., Brar, J. S., Diehl, D., Deleo, M., Madoff, D. & Martidis A. (1994). Effects of hydrocortisone infusion on rCBF in schizophrenic patients during a memory task. Annals of the NY Academy of Science, 746, 385-387.
27. Goldberg, T. E., Ragland, D., Torrey, E. F., Gold, J. M., Bigelow, L. B. & Weinberger, D. R. (1990). Neuropsychological assessment of monozygotic twins discordant for schizophrenia. Archives of General Psychiatry, 47, 1066-1072.
28. Goldberg, T. E., Torrey, E. F., Gold, J. M., Ragland, J. D., Bigelow, L. B. & Weinberger, D. R. (1993). Learning and memory in monozygotic twins discordant for schizophrenia. Psychological Medicine, 23, 71-85.
29. Goldberg, T. E. & Weinberger, D. R. (1996). Effects of neuroleptic medication on the cognition of patients with schizophrenia: a review of recent studies. Journal of Clinical Psychiatry, 57(S9), 62-65.
30. Goldman-Rakic, P. S. (1999). The physiological approach: functional architecture of working memory and disordered cognition in schizophrenia. Biological Psychiatry, 46, 650-61.
31. Goldstein, G. (1991). Comprehensive neuropsychological test batteries and research in schizophrenia. In S. R. Steinhauer, J. H. Gruzelier, & J. Zubin (Eds.), Handbook of Schizophrenia. Vol. 5. Neuropsychology, psychophysiology and information processing (pp. 525-552). Elsevier.
32. Graff-Radford, N. R., Tranel, D., Van Hoesen, G. W. & Brandt, J. P. (1990). Diencephalic amnesia. Brain, 113, 1-25.
33. Gras-Vincendon, A., Danion, J-M., Grange, D., Bilik, M., Willard-Schroeder, D., Sichel, J-P. & Singer, L. (1994). Explicit priming, repetition priming and cognitive skill learning in schizophrenia. Schizophrenia Research, 13, 117-126.
34. Green, M. F. (1996). What are the functional consequences of neurocognitive deficits in schizophrenia? American Journal of Psychiatry, 153, 321-330.
35. Green, M. F. & Neuchterlein, K. H. (1999). Should schizophrenia be treated as a neurocognitive disorder? Schizophrenia Bulletin, 25, 309-318.
36. Gur, R. E., Jaggi, J. L., Shtasel, D. L., Ragland, J. D. & Gur, R. C. (1994). Cerebral blood flow in schizophrenia: effects of memory processing on regional activation. Biological Psychiatry, 35, 3-15.
37. Harrison, P. J. (1999). The neuropathology of schizophrenia: a critical review of the data and their interpretation. Brain, 122, 593-624.
38. Haug, J. O. (1962). Pneumoencephalographic studies in mental disease. Acta Psychiatrica Scandinavica, 38 (S165), 1-114.
39. Hazlett, E. A., Buchsbaum, M. S., Byne, W., Wei, T-C., Spiegel-Cohen, J, Geneve, C., Kinderlehrer, R., Haznedar, M. M., Shihabuddin, L. & Siever, L. J. (1999). Three-dimensional analysis with MRI and PET of the size, shape, and function of the thalamus in the schizophrenic spectrum. American Journal of Psychiatry, 156, 1190-1199.
40. Hazlett, E. A., Buchsbaum, M. S., Jeu, L. A., Nenadic, I., Fleischman, M. B., Shihabuddin, L., Haznedar, M. M. & Harvey P. D. (2000). Hypofrontality in unmedicated schizophrenia patients studied with PET during performance of a serial verbal learning task. Schizophrenia Research, 43, 33-46.
41. Heckers, S., Curran, T., Goff, D., Rauch, S. L., Fischman, A. J., Alpert, N. M. & Schacter, D. L. (2000). Abnormalities in the thalamus and prefrontal cortex during episodic object recognition in schizophrenia. Biological Psychiatry, 48, 651-657.
42. Heckers, S., Goff, D., Schacter, D. L., Savage, C. R., Fischman, A. J., Alpert, N. M. & Rauch, S. L. (1999). Functional imaging of memory retrieval in deficit vs. nondeficit schizophrenia. Archives of General Psychiatry, 56, 1117-1123.
43. Heckers, S., Rauch, S. L., Goff, D., Savage, C. R., Schacter, D. L., Fischman, A. J. & Alpert, N. M. (1998). Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nature Neuroscience, 1, 318-323.
44. Hoff, A. L., Riordan, H., O'Donnell, D. W., Morris, L. & DeLisi, L. E. (1992). Neuropsychological functioning of first episode schizophreniform patients. American Journal of Psychiatry, 149, 898-903.
45. Hoff, A. L., Riordan, H., O'Donnell, D., Stritzke, P., Neale, C., Boccio, A., Anand, A. K. & DeLisi, L. E. (1992). Anomalous lateral sulcus asymmetry and cognitive function in first-episode schizophrenia. Schizophrenia Bulletin, 18, 257-269.
46. Hopkins, R. & Lewis, S. (2000). Structural imaging findings and macroscopic pathology. In P. J. Harrison & G. W. Roberts (Eds.), The neuropathology of schizophrenia (pp. 5-56). Oxford: Oxford University Press.
47. Hull, C. L. (1917). The formation and retention of associations among the insane. American Journal of Psychology, 28, 419-435.
48. Hutton, S. B., Puri, B. K., Duncan, L. J., Robbing, T. W., Barnes, T. R. E. & Joyce, E. M. (1998). Executive function in first-episode schizophrenia. Psychological Medicine, 28, 463-473.
49. Janowsky, J. S., Shimamura, A. P. & Squire, L. R. (1989). Source memory impairment in patients with frontal lobe lesions. Neuropsychologia, 27, 1043-1056.
50. Jennings, J. M., McIntosh A. R., Kapur, S., Zipursky, R. B. & Houle, S. (1998). Functional network differences in schizophrenia: a rCBF study of semantic processing. NeuroReport, 9, 1697-1700.
51. Johnson, J. H., Klingler, D. E. & Williams, T. A. (1977). Recognition in episodic long-term memory in schizophrenia. Journal of Clinical Psychology, 33, 643-647.
52. Johnson, M. K., Hashtroudi, S. & Lindsay, D. S. (1993). Source monitoring. Psychological Bulletin, 114, 3-28.
53. Johnstone, E. C., Crow, T. J., Frith, C. D., Husband, J. & Kreely, L. (1976). Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924-926.
54. Kastrup, A., Li, T-Q., Kruger, G., Glover, G. H. & Mosely, M. E. (1999). Neurophysiology: Relationship between cerebral blood flow changes during visual stimulation and baseline flow levels investigated with functional MRI. NeuroReport, 10, 1751-1756.
55. Kazes, M., Danion, J-M., Robert, P., Berthet, L., Amado, I., Willard, D. & Poirier, M-F. (1999). Impairment of consciously controlled use of memory in schizophrenia, Neuropsychology, 13, 54-61.
56. Kenny, J. T. & Meltzer, H. Y. (1991). Attention and higher cortical functions in schizophrenia. Journal of Neuropsychiatry and Clinical Neurosciences, 3, 269-275.
57. Koh, S. D. & Kayton, L. (1974). Memorization of " unrelated" word strings by young nonpsychotic schizophrenics. Journal of Abnormal Psychology, 83, 14-22.
58. Korsakoff, S. S. (1889). Psychic disorder in conjunction with peripheral neuritis. (M. Victor and P. I. Yakovlev, Trans.). Neurology (1955) 5, 394-406.
59. Kraepelin, E. (1896). Psychiatrie. Ein Lehrbuch für Studirende und Aertze (5te vollständig umgearbeitete Auflage). Leipzig: Johann Ambrosius Barth.
60. Landrø, N. I. (1994). Memory function in schizophrenia. Acta Psychiatrica Scandinavica, 90(5384), 87-94.
61. Lawrie, S. M. & Abukmeil, S. S. (1998). Brain abnormality in schizophrenia: a systematic and quantitative review of volumetric magnetic resonance imaging studies. British Journal of Psychiatry, 172, 110-120.
62. Lepage, M., Ghaffar, O., Nyberg, L. & Tulving, E. (2000). Prefrontal cortex and episodic memory retrieval mode. Proceedings of the National Association of Science USA, 97, 506-511.
63. Lewis, D. & Lieberman, J. A. (2000). Catching up on schizophrenia: natural history and neurobiology. Neuron, 28, 325-334.
64. rd ed.). New York: Oxford University Press.
65. Maher, B. A., Manschreck, T. C., Woods, B. T., Yurgelun-Todd, D. & Tsuang, M. T. (1995). Frontal brain volume and context effects in short-term recall in schizophrenia. Biological Psychiatry, 37, 144-150.
66. McCarley, R. W., Wible, C. G., Frumin, M., Hirayasu, Y., Levitt, J. J., Fischer, I. A. & Shenton, M. E. (1999). MRI anatomy of schizophrenia. Biological Psychiatry, 45, 1099-1119.
67. McCarley, R. W., Shenton, M. E., O'Donnell, B. F. & Nestor, P. G. (1993). Uniting Kraepelin and Bleuler: the psychology of schizophrenia and the biology of temporal lobe abnormalities. Harvard Review of Psychiatry, 1, 36-56.
68. McClain, L. (1983). Encoding and retrieval in schizophrenic's free recall. The Journal of Nervous and Mental Disease, 777, 471-479.
69. McKenna, P. J., Tamlyn, D., Lund, C. E., Mortimer, A. M., Hammond, S. & Baddeley, A. D. (1990). Amnesic syndrome in schizophrenia. Psychological Medicine, 20, 967-972.
70. Morel, B. A. (1860). Traité de maladies mentales. Paris: Masson.
71. Morrison, A. P. & Haddock, G. (1997). Cognitive factors in source monitoring and auditory hallucinations. Psychological Medicine, 27, 669-679.
72. Mozley, L. H., Gur, R. C., Gur, R. E., Mozley, D. & Alavi, A. (1996). Relationships between verbal memory performance and the cerebral distribution of fluorodeoxyglucose in patients with schizophrenia. Biological Psychiatry, 40, 443-451.
73. Nacmani, G. & Cohen. B. D. (1969). Recall and recognition free learning in schizophrenics. Journal of Abnormal Psychology, 74, 511-516.
74. Nelson, M. D., Saykin, A. J., Flashman, L. A. & Riordan, H. J. (1998). Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging. Archives of General Psychiatry, 55, 433-440.
75. Nestor, P. G., Shenton, M. E., McCarley, R. W., Haimson. J., Smith, S., O'Donnell, B., Kimble, M., Kikinis, R. & Jolesz, F. A. (1993). Neuropsychological correlates of MRI temporal lobe abnormalities in schizophrenia. American Journal of Psychiatry, 150, 1849-1855.
76. 99mTc-ethyl-cysteinate dimmer during a verbal learning task. Schizophrenia Research, 42, 209-222.
77. Nyberg, L. & Cabeza, R. (2000). Brain imaging of memory. In E. Tulving & F. I. M. Craik (Eds.), The Oxford handbook of memory. Oxford: Oxford University Press.
78. Nyberg, L., McIntosh, A. R., Houle, S., Nilson, L.-G. & Tulving, E. (1996). Activation of medial temporal structures during episodic memory retrieval. Nature, 380, 715-717.
79. Ober, B. A., Vinogradov, S. & Shenaut, G. K. (1997). Automatic versus controlled semantic priming in schizophrenia. Neuropsychology, 11, 506-513.
80. Park, S. & Holzman, P. S. (1992). Schizophrenics show spatial working memory deficits. Archives of General Psychiatry, 49, 975-982.
81. Paulman, R. G., Devous, M. D., Gregory R. R., Herman, J. H., Jennings, L., Bonte, F. J., Nasrallah, H. A. & Raese, J. D. (1990). Hypofrontality and cognitive impairment in schizophrenia: dynamic single-photon tomography and neuropsychological assessment of schizophrenic brain function. Biological Psychiatry, 27, 377-399.
82. Ragland, J. D., Gur, R. C., Glahn, D. C., Censits, D. M., Smith, R., Lazarev, M. G., Alavi, A. & Gur, R. E. (1998). Frontotemporal cerebral blood flow change during executive and declarative memory tasks in schizophrenia: a positron emission tomography study. Neuropsychology, 12, 399-413.
83. Raichle, M. E., Fiez, J. A., Videen, T. O., MacLeod, A. M. K., Pardo, J. V., Fox, P. T., et al. (1994). Practice-related changes in the human brain functional anatomy during nonmotor learning. Cerebral Cortex, 4, 8-26.
84. Russell, P. N. & Beekhuis, M. E. (1976). Organization in memory: a comparison of psycholics and normals. Journal of Abnormal Psychology, 83, 527-534.
85. Saykin, A. J., Gur, R. C., Gur, R. E., Mozley, D., Mozley, L. H., Resnick, S. M., Kester, D. B. & Stafiniak, P. (1991). Neuropsychological function in schizophrenia: selective impairment in memory and learning. Archives of General Psychiatry, 48, 618-624.
86. Saykin, A. J., Shtasel, D. L., Gur, R. E., Kester, D. B., Mozley, L. H., Stafiniak, P. & Gur, R. C. (1994). Neuropsychological deficits in neuroleptic naïve patients with first episode schizophrenia. Archives of General Psychiatry, 51, 124-131.
87. Schacter, D. L., Norman, K. A. & Koutsaal, W. (1998). The cognitive neuroscience of constructive memory. Annual Review of Psychology, 49, 289-318.
88. Schmahmann, J. D. (1991). An emerging concept: The cerebellar contribution to higher function. Archives of Neurology, 45, 333-356.
89. Scoville, W. B. & Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology. Neurosurgery. and Psychiatry, 20, 11-21.
90. Seidman, L. J., Yurgelun-Todd, D., Kremen, W. S., Woods, B. T., Goldstein, J. M., Faraone, S. V. & Tsaung, M. T. (1994). Relationship of prefrontal and temporal lobe MRI measures to neuropsychological performance in chronic schizophrenia. Biological Psychiatry, 35, 235-246.
91. Squire, L. R., Amaral, D. G., Zola-Morgan, S., Kritchevsky, M. & Press, G. (1989). Description of brain injury in the amnesic patient N. A. based on magnetic resonance imaging. Experimental Neurology, 105, 23-35.
92. Squire, L. R. & Zola-Morgan, S. (1991). The medial temporal lobe memory system. Science, 253, 1380-1386.
93. Stip, E. & Lussier, I. (1996). The heterogeneity of memory dysfunction in schizophrenia. Canadian Journal of Psychiatry, 41(S1), 14S-20S.
94. Stuss, D. T. & Benson, D. F. (1987). The frontal lobes and control of cognition and memory. In E. Perecman (Ed.), The frontal lobes revisited. New York: IRBN.
95. Sullivan, E. V., Shear, P. K., Lim, K. O., Zipursky, R. B. & Pfefferbaum, A. (1996). Cognitive and motor impairments are related to gray matter volume deficits in schizophrenia. Biological Psychiatry, 39, 234-240.
96. Torres, I. J., Flashman, L. A., O'Leary, D. S., Swayze, V. & Andreasen, N. C. (1997). Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biological Psychiatry, 42, 1087-1096.
97. Traupmann, K. L. (1975). Effects of categorization and imagery on recognition and recall by process and reactive schizophrenics. Journal of Abnormal Psychology, 84, 307-314.
98. Traupmann, K. L., Berzofsky, M. & Kesselman, M. (1976). Encoding of taxonomic word categories by schizophrenics. Journal of Abnormal Psychology, 85, 350-355.
99. Tulving, E., Markowitsch, H. J., Craik, F. I. M., Habib, R. & Houle, S. (1996). Novelty and familiarity activations in PET studies of memory encoding and retrieval. Cerebral Cortex, 6, 71-79.
100. nd ed.). Philadelphia: F. A. Davis Company.
101. Wagner, A. D. (1999). Working memory contributions to human learning and remembering. Neuron, 22, 19-22.
102. Weinberger, D. R. (1993). A connectionist approach to the prefrontal cortex. Journal of Neuropsychiatry and Clinical Neurosciences, 5, 241-253.
103. Weinberger, D. R., Berman, K. F., Suddath, R. & Torrey, E. F. (1992). Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: a magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. American Journal of Psychiatry, 149, 890-897.
104. Weiss, A. P. & Heckers, S. (1999). Neuroimaging of hallucinations: a review of the literature. Psychiatry Research: Neuroimaging, 92, 61-74.
105. Wiser, A. K., Andreasen, N. C., O'Leary, D. S., Watkins, G. L., Ponto, L. L. B. & Hichwa, R. D. (1998). Dysfunctional corticocerebellar circuits cause cognitive dysmetria in schizophrenia. NeuroReport, 9, 1895-1899.
106. Wood, F. B. & Flowers, D. L. (1990). Hypofrontal vs. hypo-sylvian blood flow in schizophrenia. Schizophrenia Bulletin, 16, 413-424.
107. Yener, G. G. & Zaffos, A. (1999). Memory and the frontal lobes. In B. L. Miller & J. L. Cummings (Eds.), The human frontal lobes. New York: Guilford Press.
108. Zee, R. F. & Weinberger, D. R. (1986). Relationship between CT scan findings and neuropsychological performance in chronic schizophrenia. Psychiatric Clinics of North America, 9, 49-61.
109. Zola-Morgan, S. & Squire, L. R. (1985). Amnesia in monkeys after lesions of the mediodorsal nucleus of the thalamus. Annals of Neurology, 17, 558-64.