Selectivity of verbal memory deficit in schizophrenic patients and their relatives

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 116 B, Issue 1, 2003, Pages 1-7

  Toulopoulou, Timothea ^a   Morris, Robin G ^a   Rabe Hesketh, Sophia ^a   Murray, Robin M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cognitive impairment; Executive processes; Genetic liability; Relatives; Schizophrenia; Selective deficits; Verbal memory; Visual memory

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; COGNITION; FEMALE; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; MENTAL FUNCTION; PRIORITY JOURNAL; RECALL; RELATIVE; RISK FACTOR; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; VERBAL MEMORY; VISUAL MEMORY;

EID: 0042827441     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.10027     Document Type: Article

References (52)

1. Albus M, Hubmann W, Ehrenberg Ch, Forcht U, Mohr F, Sobizack N, Wahlheim Ch, Hecht S. 1996. Neuropsychological impairment in first-episode and chronic schizophrenic patients. Eur Arch Psychiatry Clin Neurosci 246:249-255.
2. Army Individual Test Battery. 1944. Manual of directions and scoring. Washington, DC: War Department, Adjutant General's Office.
3. Baron M, Asnis L, Gruen R. 1981. The schedule for schizotypal personalities (SSP): a diagnostic interview for schizotypal features. Psychiatry Res 4:213-228.
4. Blanchard JJ, Neale JM. 1994. The neuropsychological signature of schizophrenia: generalized or differential deficit?. Am J Psychiatry 151:40-48.
5. Braff D, Heaton R, Kuck J, Cullum M, Moranville J, Grant I, Zisook S. 1991. The generalised pattern of neuropsychological deficits in outpatients with chronic schizophrenia with heterogeneous Wisconsin Card Sorting Test results. Arch Gen Psychiatry 48:894-898.
6. Byrne M, Cosway P, Hodges A, Grant E, Clafferty B, Cunningham Owens D, Johnstone EC. 2000. Neuropsychological assessment in the Edinburgh high risk for schizophrenia study. Schizophr Res 41:271.
7. Cannon TD, Zorrilla LE, Shtasel D, Gur RE, Gur RC, Marco EJ, Moberg P, Price A. 1994. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. Arch Gen Psychiatry 51:651-661.
8. Cannon TD, van Erp TGM, Huttenen M, Lohnqvist J, Salonen O, Valanne L, Poutanen V-P, Standertskjold-Nordenstam C-G, Gur RE, Yan M. 1998. Regional grey matter, white matter, and cerebrospinal fluid distributions in schizophrenic patients, their siblings, and controls. Arch Gen Psychiatry 55:1084-1091.
9. Cannon TD, Huttunen MO, Lonnqvist J, Tuulio-Henriksson A, Pirkola T, Glahn D, Finkelstein J, Hietanen M, Kaprio J, Koskenvuo M. 2000. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. Am J Hum Genet 67:369-382.
10. Censits DM, Ragland JD, Gur RC, Gur RE. 1997. Neuropsychological evidence supporting a neurodevelopmental model of schizophrenia: a longitudinal study. Schizophr Res 24:289-298.
11. Chapman LJ, Chapman JP. 1989. Strategies for resolving the heterogeneity of schizophrenics and their relatives using cognitive measures. J Abnorm Psychol 4:357-366.
12. Clementz BA, Geyer MA, Braff DL. 1998. Poor P50 Suppression among schizophrenia patients and their first-degree biological relatives. Am J Psychiatry 155:1691-1694.
13. Cornblatt B, Obuchowski M. 1997. Update of high-risk research: 1987-97. Int Rev Psychiatry 9:437-447.
14. David AS, Malmberg A, Lewis G, Brandt L, Allebeck P. 1995. Premorbid neuropsychological performance as a risk factor for schizophrenia: 13-year follow-up of 50,000 conscripts. Schizophr Res 15:114.
15. Elliott R, McKenna PJ, Robbins TW, Sahakian BI. 1998. Specific neuropsychological deficits in schizophrenic patients with preserved intellectual function. Cognitive Neuropsychiatry 3:45-70.
16. Endicott J, Spitzer R. 1978. A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 35:837-844.
17. Endicott J, Andreasen NC, Spitzer RL. 1975. Family history research diagnostic criteria. New York: New York State Psychiatric Institute, Biometrics Research Division.
18. Faraone SV, Seidman LJ, Kremen WS, Pepple JR, Lyons MJ, Tsuang MT. 1995. Neuropsychological functioning amongthe nonpsychotic relatives of schizophrenic patients: a diagnostic efficiency analysis. J Abnorm Psychol 104:286-304.
19. Faraone SV, Seidman LJ, Kremen W, Toomey R, Pepple JR, Tsuang MT. 1999. Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a 4-year follow-up study. J Abnorm Psychol 108:176-181.
20. Faraone SV, Seidman LJ, Kremen WS, Toomey R, Pepple JR, Tsuang MT. 2000. Neuropsychologic functioning among the nonpsychotic relatives of schizophrenic patients: the effect of genetic loading. Biol Psychiatry 48:120-126.
21. Frangou S, Sharma T, Alarcon G, Sigmudsson T, Takei N, Binnie C, Murray RM. 1997a. The Maudsley Family Study 2. Endogenous event-related potentials in familial schizophrenia. Schizophr Res 23:45-53.
22. Frangou S, Sharma T, Sigmudsson T, Barta P, Pearlson G, Murray RM. 1997b. The Maudsley Family Study 4. Normal planum temporale asymmetry in familial schizophrenia. Br J Psychiatry 170:328-333.
23. Friedman D, Squires-Wheeler E. 1994. Event-related potentials (ERPs) as indicators of risk for schizophrenia. Schizophr Bull 20:63-74.
24. Goldberg TE, Torrey EF, Gold JM, Ragland JD, Bigelow LB, Weinberger DR. 1993. Learning and memory in monozygotic twins discordant for schizophrenia. Psychol Med 23:71-85.
25. Goldberg TE, Torrey EF, Gold JM, Bigelow LB, Ragland RD, Taylor E, Weinberger DR. 1995. Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder. Schizophr Res 17:77-84.
26. Goldstein LH, Canavan AGM, Polkey CE. 1988. Verbal and abstract designs paired associate learning after unilateral and temporal lobectomy, Cortex 24:41-52.
27. Griffiths TD, Sigmundsson T, Takei N, Rowe D, Murray RM. 1998. Neurological abnormalities in familial and sporadic schizophrenia. Brain 121:191-203.
28. Hawkins KA, Sullivan TE, Choi EJ. 1997. Memory deficits in schizophrenia: inadequate assimilation or true amnesia? Findings from the Wechsler Memory Scale-revised. J Psychiatry Neurosci 22:169-179.
29. Jones P. 1995. Childhood motor milestones and IQ prior to adult schizophrenia: results from a 43-year-old British birth cohort. Psychiatria Fennica 26:63-80.
30. Keefe RSE, Silverman JM, Lees Roitman SE, Harvey PD, Duncan MA, Alroy D, Siever LJ, Davis KL, Mohs RC. 1994. Performance of nonpsychotic relatives of schizophrenic patients on cognitive tests. Psychiatry Res 53:1-12.
31. Krabbendam L, Marcelis M, Delespaul P, Jolles J, Van Os J. 2001. Single or multiple familial cognitive risk factors in schizophrenia? Am J Med Genet 105:183-188.
32. Kremen WS, Seidman LJ, Pepple JR, Lyons MJ, Tsuang MT, Faraone SV. 1994. Neuropsychological risk indicators for schizophrenia: a review of family studies. Schizophr Bull 20:103-119.
33. Laurent A, Moreaud O, Bosson JL, Naëgelé B, Boucharlat J, Saoud M, Dalery J, d'Amato T. 1999. Neuropsychological functioning among non-psychotic siblings and parents of schizophrenic patients. Psychiatry Res 87:147-157.
34. Lawrie SM, Whalley H, Kestelman JN, Abukmeil SS, Byrne M, Hodges A, Rimmington JE, Best JJK, Owens DGC, Johnstone EC. 1999. Magnetic resonance imaging of brain in people at high risk of developing schizophrenia. Lancet 353:30-33.
35. Lezak MD. 1995. Neuropsychological assessment. New York: Oxford University Press.
36. Lyons MJ, Toomey R, Seidman LJ, Kremen WS, Faraone SV, Tsuang MT. 1995. Verbal learning and memory in relatives of schizophrenics: preliminary findings. Biol Psychiatry 37:750-753.
37. Miotto EC, Bullock P, Polkey CE, Morris RG. 1996. Spatial working memory and strategy formation in patients with frontal lobe excisions. Cortex 32:613-630.
38. Morris RG, Rushe T, Woodruffe PWR, Murray RM. 1995. Problem solving in schizophrenia: a specific deficit in planning ability. Schizophr Res 14: 235-246.
39. Nopoulos P, Flashman L, Flaum M, Arndt S, Andreasen N. 1994. Stability of cognitive functioning early in the course of schizophrenia. Schizophr Res 14:29-37.
40. Nurnberger JI, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T. 1994. Diagnostic interview for genetic studies. Rationale, unique features and training. NIMH Genetics Initiative. Arch Gen Psychiatry 51:849-859.
41. Park S, Holzman PS, Goldman-Rakic PS. 1995. Spatial working memory deficits in the relatives of schizophrenic patients. Arch Gen Psychiatry 52:821-828.
42. Rabe-Hesketh S, Toulopoulou T, Murray R. 2001. Multilevel modelling of cognitive function in schizophrenic patients and their first degree relatives. Special issue of Multivariate Behavioral Research on multilevel modelling. Multivariate Behav Res 36:279-298.
43. Rund BR. 1998. A review of longitudinal studies of cognitive functions in schizophrenia patients. Schizophr Bull 24:425-435.
44. Saykin AJ, Gur RC, Gur RE, Mozley PD, Mozley LH, Resnick SM, Kester DB, Stafiniak P. 1991. Neuropsychological function in schizophrenia. Selective impairment in memory and learning. Arch Gen Psychiatry 48:618-624.
45. Saykin AJ, Shtasel DL, Gur RE, Kester DB, Mozley LH, Stafiniak P, Gur RC. 1994. Neuropsychological deficits in neuroleptic naive patients with first episode schizophrenia. Arch Gen Psychiatry 51:124-131.
46. Seidman LJ, Faraone SV, Goldstein JM, Goodman JM, Kremen WS, Matsuda G, Hoge EA, Kenndey D, Makris N, Caviness VS, Tsuang MT. 1997. Reduced subcortical brain volumes in nonpsychotic siblings of schizophrenic patients: a pilot magnetic resonance imaging study. Am J Med Genet 74:507-514.
47. Sharma T, Lancaster E, Lee D, Lewis S, Sigmundsson T, Takei N, Gurling H, Barta P, Pearlson G, Murray R. 1998. Brain changes in schizophrenia. Volumetric MRI study of families multiply affected with schizophrenia. The Maudsley Family Study 5. Br J Psychiatry 173:132-138.
48. Sharma T, Lancaster E, Sigmundsson T, Lewis S, Takei N, Gurling H, Barta P, Pearlson G, Murray R. 1999. Lack of normal pattern of cerebral asymmetry in familial schizophrenic patients and their relatives. The Maudsley Family Study. Schizophr Res 40:111-120.
49. Sullivan EV, Shear PK, Zipursky RB, Sagar HJ, Pfefferbaum A. 1994. A deficit profile of executive, memory, and motor functions in schizophrenia. Biol Psychiatry 36:641-653.
50. Toomey R, Faraone SV, Seidman LJ, Kremen WS, Pepple JR, Tsuang MT. 1998. Association of neuropsychological vulnerability markers in relatives of schizophrenic patients. Schizophr Res 31:89-98.
51. Wechsler D. 1981. Wechsler Adult Intelligence Scale-revised manual. New York: Psychological Corporation.
52. Wechsler D, Stone CP. 1945. Manual for the Wechsler Memory Scale. New York: Psychological Corporation.