Inhibition of MMP-dependent chemotaxis and amelioration of experimental autoimmune uveitis with a selective metalloproteinase-2 and -9 inhibitor

Journal of Neuroimmunology

Volumn 155, Issue 1-2, 2004, Pages 13-20

  El Shabrawi, Yosuf ^a   Walch, Astrid ^a   Hermann, Josef ^a   Egger, Gerhard ^a   Foster, C Stephen ^a,b  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Autoimmunity; Cell trafficking; EAU; MMP; Rodent; T lymphocytes; Uveitis

Indexed keywords

COLLAGEN; CYSTEINYLARGINYLALANYLVALYLARGINYLALANYLLEUCYLTRYPTOPHYLARGINYLCYSTEINE; CYSTEINYLTHREONYLTHREONYLHISTIDYLTRYPTOPHYLGLYCYLPHENYLALANYLTHREONYL LEUCYLCYSTEINE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE; UVEITIS;

AMINO ACID MOTIFS; ANIMALS; AUTOIMMUNE DISEASES; BASEMENT MEMBRANE; BIOLOGICAL MARKERS; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FEMALE; MACROPHAGES; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MONOCYTES; PEPTIDE FRAGMENTS; RETINA; T-LYMPHOCYTES; TREATMENT OUTCOME; UVEITIS;

EID: 4444226050     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.05.010     Document Type: Article

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