QSAR study of β-lactam antibiotic efflux by the bacterial multidrug resistance pump AcrB

Journal of Chemometrics

Volumn 18, Issue 5, 2004, Pages 242-252

  Ferreira, Márcia M C ^a   Kiralj, R ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

AcrB multidrug resistance efflux pump; PLS; QSAR; lactam antibiotics

Indexed keywords

AMIDES; BACTERIA; BINDING ENERGY; COMPUTATIONAL CHEMISTRY; HYDROGEN; HYDROGEN BONDS; REGRESSION ANALYSIS;

ACRB MULTIDRUG RESISTANCE EFFLUX PUMP; EFFLUX PUMPS; LIPOPHILICITY; LIPOPHILICITY PARAMETERS; MULTIDRUG RESISTANCE; PLS; PROPERTY; QSAR; QSAR STUDIES; Β-LACTAM ANTIBIOTICS;

ANTIBIOTICS;

ACRAB TOLC EFFLUX PUMP; ADICILLIN; AMPHOPHILE; BETA LACTAM ANTIBIOTIC; CARBENICILLIN; CEFALORIDINE; CEFALOTIN; CEFAZOLIN; CEFMETAZOLE; CEFOTAXIME; CEFOXITIN; CEFSULODIN; CEFTRIAXONE; CEPHALOSPORIN C; CLOXACILLIN; DRUG CARRIER; ERYTHROMYCIN; HEXANE; LATAMOXEF; NAFCILLIN; NITROGEN; PENICILLIN G; RIFAMPICIN; SULBENICILLIN; SULFUR; TOLC PROTEIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; CALCULATION; CLASSIFICATION; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; DIPOLE; DRUG TRANSPORT; GRAM NEGATIVE BACTERIUM; HYDROGEN BOND; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; QUANTITATIVE DIAGNOSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; STEREOCHEMISTRY; STRAIN DIFFERENCE; STRAIN IDENTIFICATION;

EID: 4444223842     PISSN: 08869383     EISSN: None     Source Type: Journal    
DOI: 10.1002/cem.867     Document Type: Conference Paper

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