Synthesis and biological activities of a series of 4,5-diaryl-3-hydroxy-2(5H)-furanones

European Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2008, Pages 1222-1229

  Bailly, Fabrice ^a   Queffélec, Clémence ^a   Mbemba, Gladys ^b   Mouscadet, Jean François ^b   Pommery, Nicole ^c   Pommery, Jean ^c   Hénichart, Jean Pierre ^c   Cotelle, Philippe ^a  

^a UNIV LILLE   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

Author keywords

3 Hydroxy 2 (5H) furanones; 5 Lipoxygenase; Antioxidant; Cyclooxygenases; HIV 1 integrase; PC3 proliferation

Indexed keywords

3 HYDROXY 4 (4 HYDROXYPHENYL) 5 (4 HYDROXYPHENYL) 2(5H) FURANONE; 3 HYDROXY 4 (4 HYDROXYPHENYL) 5 PHENYL 2(5H) FURANONE; 4 (4 FLUOROPHENYL) 3 HYDROXY 5 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (3,4 DIBENZYLOXYPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (3,4 DIBENZYLOXYPHENYL) 4 (4 FLUOROPHENYL) 3 HYDROXY 2(5H) FURANONE; 5 (3,4 DIHYDROXYPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (3,5 DIBENZYLOXYPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (3,5 DIBENZYLOXYPHENYL) 4 (4 FLUOROPHENYL) 3 HYDROXY 2(5H) FURANONE; 5 (3,5 DIHYDROXYPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (3,5 DIHYDROXYPHENYL) 4 (4 FLUOROPHENYL) 3 HYDROXY 2(5H) FURANONE; 5 (4 BENZYLOXYPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; 5 (4 BENZYLOXYPHENYL) 4 (4 FLUOROPHENYL) 3 HYDROXY 2(5H) FURANONE; 5 (4 FLUOROPHENYL) 3 HYDROXY 4 (4 HYDROXYPHENYL) 2(5H) FURANONE; ANTIOXIDANT; ARACHIDONATE 5 LIPOXYGENASE; CELECOXIB; FURANONE DERIVATIVE; INTEGRASE; PROSTAGLANDIN SYNTHASE;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION;

BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; FURANS; HIV INTEGRASE INHIBITORS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY;

EID: 44349164437     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.08.005     Document Type: Article

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