Copper (Cu2+) induces degeneration of dopaminergic neurons in the nigrostriatal system of rats

Neuroscience Bulletin

Volumn 24, Issue 2, 2008, Pages 73-78

  Yu, Wen Ran ^a   Jiang, Hong ^a   Wang, Jun ^a   Xie, Jun Xia ^a  

^a QINGDAO UNIVERSITY   (China)

Author keywords

Copper; Dopamine; Rats; Substantia nigra

Indexed keywords

ANTIOXIDANT; CASPASE 3; COPPER; MESSENGER RNA; TYROSINE 3 MONOOXYGENASE; COPPER ZINC SUPEROXIDE DISMUTASE; DOPAMINE; NEUROTOXIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DAMAGE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MESENCEPHALON; METABOLITE; METHODOLOGY; NERVE DEGENERATION; NERVE FIBER; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; STAINING; SUBSTANTIA NIGRA; WISTAR RAT; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; GENETICS; METABOLISM; NERVE CELL; NERVE TRACT; OXIDATIVE STRESS; PARKINSONISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; AXONS; CASPASE 3; COPPER; CORPUS STRIATUM; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NERVE DEGENERATION; NEURAL PATHWAYS; NEURONS; NEUROTOXINS; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; RATS; RATS, WISTAR; RNA, MESSENGER; SUBSTANTIA NIGRA; SUPEROXIDE DISMUTASE; TYROSINE 3-MONOOXYGENASE; WALLERIAN DEGENERATION;

EID: 44349129732     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-008-0073-y     Document Type: Article

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