Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides

PLoS ONE

Volumn 3, Issue 4, 2008, Pages

  Dan, Jennifer M ^a,b   Wang, Jennifer P ^b   Lee, Chrono K ^b   Levitz, Stuart M ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD206 ANTIGEN; CELL RECEPTOR; CHEMOKINE; CPG OLIGODEOXYNUCLEOTIDE; CRYPTOCOCCUS NEOFORMANS MANNOPROTEIN; CYTOKINE; FUNGAL PROTEIN; IMIQUIMOD; LIGAND; LIPOPEPTIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNOPROTEIN; MANNOSE RECEPTOR; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR LIGAND; AUTACOID; CELL SURFACE RECEPTOR; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; LECTIN; MANNOPROTEINS; MANNOSE BINDING LECTIN; MEMBRANE PROTEIN; OLIGODEOXYRIBONUCLEOTIDE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL STIMULATION; CRYPTOCOCCUS NEOFORMANS; CYTOKINE PRODUCTION; DENDRITIC CELL; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL COMPARTMENTALIZATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; HYBRIDOMA; IMMUNOLOGY; INTRACELLULAR SPACE; METABOLISM; T LYMPHOCYTE;

FILOBASIDIELLA NEOFORMANS; MURINAE;

ANIMALS; CELL COMPARTMENTATION; CHEMOKINES; CRYPTOCOCCUS NEOFORMANS; DENDRITIC CELLS; HYBRIDOMAS; INFLAMMATION MEDIATORS; INTRACELLULAR SPACE; LECTINS, C-TYPE; LIGANDS; MANNOSE-BINDING LECTINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, CELL SURFACE; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 44349125049     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002046     Document Type: Article

References (40)

1. Trinchieri G, Sher A (2007) Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 7: 179-190.
2. Kawai T, Akira S (2007) TLR signaling. Semin Immunol 19: 24-32.
3. Krieg AM (2006) Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 5: 471-484.
4. Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, et al. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 5: 190-198.
5. Hacker H, Vabulas RM, Takeuchi O, Hoshino K, Akira S, et al. (2000) Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and turner necrosis factor receptor-associated factor (TRAF)6. J Exp Med 192: 595-600.
6. Honda K, Yanai H, Negishi H, Asagiri M, Sato M, et al. (2005) IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434: 772-777.
7. Cambi A, Figdor CG (2003) Dual function of C-type lectin-like receptors in the immune system. Curr Opin Cell Biol 15: 539-546.
8. Robinson MJ, Sancho D, Slack EC, LeibundGut-Landmann S, Reis e Sousa C (2006) Myeloid C-type lectins in innate immunity. Nat Immunol 7: 1258-1265.
9. Bicanic T, Harrison TS (2004) Cryptococcal meningitis. Br Med Bull 72: 99-118.
10. Levitz SM, Specht CA (2006) The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins. FEMS Yeast Res 6: 513-524.
11. Mansour MK, Schlesinger LS, Levitz SM (2002) Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors. J Immunol 168: 2872-2879.
12. Levitz, SM, Nong S, Mansour MK, Huang C, Specht CA (2001) Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans. Proc Natl Acad Sci U S A 98: 10422-10427.
13. Mansour MK, Latz E, Levitz SM (2006) Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells. J Immunol 176: 3053-3061.
14. Mansour MK, Yauch LE, Rottman JB, Levitz SM (2004) Protective efficacy of antigenic fractions in mouse models of cryptococcosis. Infect Immun 72: 1746-1754.
15. Murphy JW, Mosley RL, Cherniak R, Reyes GH, Kozel TR, et al. (1988) Serological, electrophoretic, and biological properties of Cryptococcus neoformans antigens. Infect Immun 56: 424-431.
16. Guy B (2007) The perfect mix: recent progress in adjuvant research. Nat Rev Microbiol 5: 505-517.
17. Edwards L, Williams AE, Krieg AM, Rae AJ, Snelgrove RJ, et al. (2005) Stimulation via Toll-like receptor 9 reduces Cryptococcus nenformans-induced pulmonary inflammation in an IL-12-dependent manner. Eur J Immunol 35: 273-281.
18. Miyagi K, Kawakami K, Kirjo Y, Uezu K, Kinjo T, et al. (2005) CpG oligodeoxynucleotides promote the host protective response against infection with Cryptococcus neoformans through induction of interferon-gamma production by CD4-+ T cells. Clin Exp Immunol 140: 220-229.
19. Kinjo T, Miyagi K, Nakamura K, Higa F, Gang X, et al. (2007) Adjuvant Effect of CpG-Oligodeoxynucleotide in Anti-Fungal Chemotherapy against Fatal Infection with Cryptococcus nenformans in Mice. Microbiol Immunol 51: 741-746.
20. Herring AC, Lee J, McDonald RA, Toews GB, Huffnagle GB (2002) Induction of Interleukin-12 and Gamma Interferon Requires Tumor Necrosis Factor Alpha for Protective T1-Cell-Mediated Immunity to Pulmonary Cryptococcus neoformans Infection. Infect Immun 70: 2959-2964.
21. Specht CA, Nong S, Dan JM, Lee CK, Levitz SM (2007) Contribution of Glycosylation to T Cell Responses Stimulated by Recombinant Cryptococcus neoformans Mannoprotein. J Infect Dis 196: 796-800.
22. Hochrein H, O'Keeffe M, Wagner H (2002) Human and mouse plasmacytoid dendritic cells. Hum Immunol 63: 1103-1110.
23. Park CG, Takahara K, Umemoto E, Yashima Y, Matsubara K, et al. (2001) Five mouse homologues ofthe human dendritic cell C-type lectin, DC-SIGN. Int Immunol 13: 1283-1290.
24. Pictrella D, Corbucci C, Perito S, Bistoni G, Vecchiarelli A (2005) Mannoproteins from Cryptococcus neoformans promote dendritic cell maturation and activation. Infect Immun 73: 820-827.
25. Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 197: 1107-1117.
26. Taylor PR, Tsoni SV, Willment JA, Dennehy KM, Rosas M, et al. (2007) Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat Immunol 8: 31-38.
27. Saijo S, Fujikado N, Furuta T, Chung SH, Kotaki H, et al. (2007) Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat Immunol 8: 39-46.
28. Netea MG, Gow NA, Munro CA, Bates S, Collins C, et al. (2006) Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors. J Clin Invest 116: 1642-1650.
29. Shoham S, Levitz SM (2005) The immune response to fungal infections. Br J Haematol 129: 569-582.
30. Rogers NC, Slack EC, Edwards AD, Nolte MA, Schulz O, et al. (2005) Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity 22: 507-517.
31. Taylor PR, Gordon S, Martinez-Pomares L (2005) The mannose receptor: linking homeostasis and immunity through sugar recognition. Trends Immunol 26: 104-110.
32. Chieppa M, Bianchi G, Doni A, Del Prete A, Sironi M, et al. (2003) Cross-linking of the mannose receptor on monocyte-derived dendritic cells activates an anti-inflammatory immunosuppressive program. J Immunol 171: 4552-4560.
33. Zhang J, Zhu J, Imrich A, Cushion M, Kinane TB, et al. (2004) Pneumocystis activates human alveolar macrophage NF-kappaB signaling through mannose receptors. Infect Immun 72: 3147-3160.
34. Lee SJ, Even S, Roeder D, Parlow AF, Risteli J, et al. (2002) Mannose receptor- mediated regulation of serum glycoprotein homeostasis. Science 295: 1898-1901.
35. Hazcki K, Nigorikawa K, Hazeki O (2007) Role of phosphoinositide 3-kinase in innate immunity. Biol Pharm Bull 30: 1617-1623.
36. Blander JM, Medzhitov R (2006) On regulation of phagosome maturation and antigen presentation. Nat Immunol 7: 1029-1035.
37. Blander JM, Medzhitov R (2006) Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440: 808-812.
38. Ramakrishna V, Vasilakos JP, Tario JD Jr, Berger MA, Wallace PK, et al. (2007) Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells. J Transl Med 5: 5.
39. Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ (2000) Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 165: 618-622.
40. Lutz MB, Kukutsch N, Ogilvie AL, Rossner S, Koch F, et al. (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223: 77-92.