Impact of ambiguity and risk on decision making in mild Alzheimer's disease

Neuropsychologia

Volumn 46, Issue 7, 2008, Pages 2043-2055

  Sinz, H ^a   Zamarian, L ^a   Benke, T ^a   Wenning, G K ^a   Delazer, M ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Ambiguity; DAT; Decision; Risk

Indexed keywords

ALZHEIMER DISEASE; AMBIGUITY; ARTICLE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONFLICT; DAILY LIFE ACTIVITY; DECISION MAKING; EMOTION; FEMALE; HUMAN; INFORMATION; MALE; RISK ASSESSMENT; TASK PERFORMANCE;

AGED; ALZHEIMER DISEASE; AWARENESS; CHOICE BEHAVIOR; COGNITION DISORDERS; CONFLICT (PSYCHOLOGY); CONTROL GROUPS; DECISION MAKING; FEMALE; GAMBLING; HUMANS; IMPULSE CONTROL DISORDERS; JUDGMENT; MALE; NEUROPSYCHOLOGICAL TESTS; PROBABILITY; PROBLEM SOLVING; REACTION TIME; RISK-TAKING;

EID: 44349120142     PISSN: 00283932     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropsychologia.2008.02.002     Document Type: Article

References (105)

1. Almeida O.P., Burton E.J., McKeith I., Gholkar A., Burn D., and O'Brien J.T. MRI study of caudate nucleus volume in Parkinson's disease with and without dementia with Lewy bodies and Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 16 2 (2003) 57-63
2. Beach T.G., Kuo Y.M., Spiegel K., Emmerling M.R., Sue L.I., Kokjohn K., et al. The cholinergic deficit coincides with a beta deposition at the earliest histopathologic stages of Alzheimer disease. Journal of Neuropathology and Experimental Neurology 59 4 (2000) 308-313
3. Bechara A., Damasio A.R., Damasio H., and Anderson S.W. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50 (1994) 7-15
4. Bechara A., Tranel D., Damasio H., and Damasio A.R. Failure to respond autonomically to anticipated future outcomes following damage to prefrontal cortex. Cerebral Cortex 6 (1996) 215-225
5. Bechara A., Damasio H., Tranel D., and Anderson S.W. Dissociation of working memory from decision-making within the human prefrontal cortex. Journal of Neuroscience 18 (1998) 428-437
6. Bechara A., Damasio H., Damasio A.R., and Lee G.P. Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making. Journal of Neuroscience 19 13 (1999) 5473-5481
7. Bechara A., Tranel D., and Damasio H. Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions. Brain 123 11 (2000) 2189-2202
8. Bechara A., Dolan S., Denburg N., Hindes A., Anderson S.W., and Nathan P.E. Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. Neuropsychologia 39 (2001) 376-389
9. Berres M., Monsch A.U., Bernasconi F., Thalmann B., and Stahelin H.B. Normal ranges of neuropsychological tests for the diagnosis of Alzheimer's disease. Studies in Health Technology and Informatics 77 (2000) 195-199
10. Bolla K.I., Eldreth D.A., Matochik J.A., and Cadet J.L. Sex related differences in a gambling task and its neurological correlates. Cerebral Cortex 14 (2004) 1226-1232
11. Boller F., El Massioui F., Devouche E., Traykov L., Pomati S., and Starkstein S.E. Processing emotional information in Alzheimer's disease: Effects on memory performance and neurophysiological correlates. Dementia and Geriatric Cognitive Disorders 14 2 (2002) 104-112
12. Braak H., and Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica (Berl) 82 (1991) 239-259
13. Brand M., Fujiwara E., Kalbe E., Steingass H.P., Kessler J., and Markowitsch H.J. Cognitive estimation and affective judgments in alcoholic Korsakoff patients. Journal of Clinical and Experimental Neuropsychology 25 3 (2003) 324-334
14. Brand M., Kalbe E., Fujiwara E., Huber M., and Markowitsch H.J. Cognitive estimation in patients with probable Alzheimer's disease and alcoholic Korsakoff patients. Neuropsychologia 41 5 (2003) 575-584
15. Brand M., Labudda K., Kalbe E., Hilker R., Emmans D., Fuchs G., Kessler J., et al. Decision-making impairments in patients with Parkinson's disease. Behavioural Neurology 15 (2004) 77-85
16. Brand M., Fujiwara E., Borsutzky S., Kalbe E., Kessler J., and Markowitsch H.J. Decision-making deficits of korsakoff patients in a new gambling task with explicit rules: Associations with executive functions. Neuropsychology 19 (2005) 267-277
17. Brand M., Kalbe E., Labudda K., Fujiwara E., Kessler J., and Markowitsch H.J. Decision-making impairments in patients with pathological gambling. Psychiatry Research 133 (2005) 91-99
18. Brand M., Labudda K., and Markowitsch H.J. Neuropsychological correlates of decision-making in ambiguous and risky situations. Neural Networks 19 8 (2006) 1266-1276
19. Brand M., Grabenhorst F., Starcke K., Vandekerckhove M.M.P., and Markowitsch H.J. Role of the amygdala in decisions under ambiguity and decisions under risk. Evidence from patients with Urbach Wiethe disease. Neuropsychologia 45 6 (2007) 1305-1317
20. Brand M., Recknor E.C., Grabenhorst F., and Bechara A. Decisions under ambiguity and decisions under risk: Correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules. Journal of Clinical and Experimental Neuropsychology 29 1 (2007) 86-99
21. Bucks R.S., and Radford S.A. Emotion processing in Alzheimer's disease. Aging and Mental Health 8 3 (2004) 222-232
22. Busemeyer J.R., and Stout J.C. A contribution of cognitive decision models to clinical assessment: Decomposing performance on the Bechara gambling task. Psychological Assessment 14 (2002) 253-262
23. Campbell M.C., Stout J.C., and Finn P.R. Reduced autonomic responsiveness to gambling task losses in Huntington's disease. Journal of the International Neuropsychological Society 10 (2004) 239-245
24. Carlomagno S., Iavarone A., Nolfe G., Bourene G., Martin C., and Deloche G. Dyscalculia in the early stages of Alzheimer's disease. Acta Neurologica Scandinavica 99 (1999) 166-174
25. Carstensen L.L., and Mikels J.L. At the intersection of emotion and cognition: Aging and positivity effect. Current Directions in Psychological Science 14 3 (2005) 117-121
26. Carstensen L.L., Isaacowitz D.M., and Charles S.T. Taking time seriously: A theory of socioemotional selectivity. The American Psychologist 54 (1999) 165-181
27. Cavedini P., Riboldi G., D'Annucci A., Belotti P., Cisima M., and Bellodi L. Decision-making heterogeneity in obsessive-compulsive disorder: Ventromedial prefrontal cortex function predicts different treatment outcomes. Neuropsychologia 40 (2002) 205-211
28. Cavedini P., Riboldi G., Keller R., D'Annucci A., and Bellodi L. Frontal lobe dysfunction in pathological gambling patients. Biological Psychiatry 51 (2002) 334-341
29. Chu C.C., Tranel D., Damasio A.R., and Van Hoesen G.W. The autonomic-related cortex: Pathology in Alzheimer's disease. Cerebral Cortex 7 (1997) 86-95
30. Cools R., Barker R.A., Sahakian B.J., and Robbins T.W. L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. Neuropsychologia 41 (2003) 1431-1441
31. Crone E.A., and van der Molen M.W. Developmental changes in real life decision making: Performance on a gambling task previously shown to depend on the ventromedial prefrontal cortex. Developmental Neuropsychology 25 3 (2004) 251-279
32. Czernecki V., Pillon B., Houeto J.L., Pochon J.B., Levy R., and Dubois B. Motivation, reward, and Parkinson's disease: Influence of dopatherapy. Neuropsychologia 40 (2002) 2257-2267
33. Damasio A.R. Descartes error: Emotion, reason and the human brain (1994), Avon, New York
34. Damasio A.R. The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 351 (1996) 1413-1420
35. Damasio A.R., Tranel D., and Damasio H. Somatic markers and the guidance of behaviour: Theory and preliminary testing. In: Levin H.S., Eisenberg H.M., and Benton A.L. (Eds). Frontal lobe function and dysfunction (1991), Oxford University Press, New York
36. Delazer M., and Benke T. Arithmetic facts without meaning. Cortex 33 4 (1997) 697-710
37. Delazer M., Karner E., Proell S., and Benke T. Counting complex dot patterns in Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology 28 5 (2006) 721-731
38. Delazer M., Karner E., Zamarian L., Donnemiller E., and Benke T. Number processing in posterior cortical atrophy-a neuropsycholgical case study. Neuropsychologia 44 1 (2006) 36-51
39. Delazer M., Sinz H., Zamarian L., and Benke T. Decision-making with explicit and stable rules in mild Alzheimer's disease. Neuropsychologia 45 8 (2007) 1632-1641
40. Della Sala S., MacPherson S.E., Phillips L.H., Sacco L., and Spinnler H. The role of semantic knowledge on the cognitive estimation task-evidence from Alzheimer's disease and healthy adult aging. Journal of Neurology 251 2 (2004) 156-164
41. Deloche G., Hannequin D., Carlomagno S., Agniel A., Dordain M., Pasquier F., et al. Calculation and number processing in mild Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology 17 (1995) 634-639
42. Denburg N.L., Tranel D., Bechara A., and Damasio A.R. Normal ageing may compromise the ability to decide advantageously. Brain and Cognition 47 (2001) 156-159
43. Denburg N.L., Tranel D., and Bechara A. The ability to decide advantageously declines prematurely in some normal older persons. Neuropsychologia 43 (2005) 1099-1106
44. Dubois B., Slachevsky A., Litvan I., and Pillon B. The FAB: A frontal assessment battery at bedside. Neurology 55 11 (2000) 1601-1602
45. Dunn B.D., Dalgleish T., and Lawrence A.D. The somatic marker hypothesis: A critical evaluation. Neuroscience and Biobehavioural Reviews 30 (2006) 239-271
46. Fein G., McGillivray S., and Finn P. Older adults make less advantageous decisions than younger adults: Cognitive and psychological correlates. Journal of the International Neuropsychological Society 13 3 (2007) 480-489
47. Flowers K.A., and Robertson C. The effect of Parkinson's disease on the ability to maintain a mental set. Journal of Neurology, Neurosurgery and Psychiatry 48 6 (1985) 517-529
48. Folstein M.F., Folstein S.E., and McHugh P.R. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research 12 (1975) 189-198
49. Garon N., and Moore C. Complex decision-making in early childhood. Brain & Cognition 55 (2004) 158-170
50. Gutbrod K., Krouzel C., Hofer H., Muri R., Perrig W., and Ptak R. Decision-making in amnesia: Do advantageous decisions require conscious knowledge of previous behavioural choices?. Neuropsychologia 44 (2006) 1315-1324
51. Hachinski V.C., Iliff L.D., Zilhka E., Du Boulay G.H., McAllister V.L., Marshall J., et al. Cerebral blood flow in dementia. Archives of Neurology 32 (1975) 632-637
52. Hamann S., Monarch E.S., and Goldstein F.C. Impaired fear conditioning in Alzheimer's disease. Neuropsychologia 40 (2002) 1187-1195
53. Herholz K., Salmon E., Perani D., et al. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage 17 1 (2002) 302-316
54. Herrmann C., Buss U., and Snaith R.P. Hospital anxiety and depression scale-German Version (HADS-D). Manual (1995), Hans Huber, Bern
55. Hinson J.M., Jameson T.L., and Whitney P. Somatic markers, working memory and decision making. Cognitive Affective and Behavioural Neuroscience 2 4 (2002) 341-353
56. Hooper C.J., Luciana M., Conklin H.M., and Yarger R.S. Adolescents performance on the Iowa Gambling Task: Implications for the development of decision making and ventromedial prefrontal cortex. Developmental Psychology 40 6 (2004) 1148-1158
57. Hsu M., Bhatt M., Adolphs M., Tranel D., and Camerer C.F. Neural systems responding to degrees of uncertainty in human decision-making. Science 310 5754 (2005) 1680-1683
58. Huettel S.A., Stowe C.J., Gordon E.M., Warner B.T., and Platt M.L. Neural signatures of economic preferences for risk and ambiguity. Neuron 49 5 (2006) 765-775
59. Jackson M., and Warrington E.K. Arithmetic skills in patients with unilateral cerebral lesions. Cortex 22 (1986) 611-620
60. Kerr A., and Zelazo P.D. Development of "hot" executive function: The children's gambling task. Brain and Cognition 55 1 (2004) 148-157
61. Kessler J., and Kalbe E. Written numeral transcoding in patients with Alzheimer's disease. Cortex 32 4 (1996) 755-761
62. Lafleche G., and Albert M.S. Executive function deficits in mild Alzheimer's disease. Neuropsychology 9 (1995) 313-320
63. Lamar M., and Resnick S.M. Aging and prefrontal functions: Dissociating orbitofrontal and dorsolateral abilities. Neurobiology of Aging 25 (2004) 553-558
64. Levin I.P., and Hart S.S. Risk preferences in young children: Early evidence of individual differences in reaction to potential gains and losses. Journal of Behavioural decision making 16 5 (2003) 397-413
65. Levinoff E.J., Phillips N.A., Verret L., Babins L., Kelner N., Akerib V., et al. Cognitive estimation impairment in Alzheimer disease and mild cognitive impairment. Neuropsychology 20 1 (2006) 123-132
66. Lezak M.D. Neuropsychological Assessment (1998), Oxford University Press, New York
67. Loewenstein G., and Lerner J.S. The role of affect in decision making. In: Davidson R.J., Scherer K.R., and Goldsmith H.H. (Eds). Handbook of affective sciences (2003), Oxford University Press, Oxford 619-642
68. Mantovan M.C., Delazer M., Ermani M., and Denes G. The breakdown of calculation procedures in Alzheimer's disease. Cortex 35 (1999) 21-38
69. Martini L., Domahs F., Benke T., and Delazer M. Everyday numerical abilities in Alzheimer's disease. Journal of the International Neuropsychological Society 9 6 (2003) 871-878
70. Mather M. Aging and emotional memory. In: Reisberg D., and Hertel P. (Eds). Memory and emotion (2004), Oxford University Press, London 272-307
71. Mather M. A review of decision making processes: Weighing the risks and benefits of aging. In: Carstensen L.L., and Hartel C.R. (Eds). When I'm 64. Committee on aging frontiers in social psychology, personality, and adult developmental psychology (2006), The National Academies Press, Washington, DC 145-173
72. Mather M., and Carstensen L.L. Aging and motivated cognition: The positivity effect in attention and memory. Trends in Cognitive Sciences 9 (2005) 496-502
73. Mather M., and Johnson M.K. Choice-supportive source monitoring: Do our decisions seem better to us as we age?. Psychology and Aging 15 (2000) 596-606
74. Mather M., Knight M., and McCaffrey M. The allure of the alignable: False memories of choice features. Journal of Experimental Psychology 134 1 (2005) 38-51
75. McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34 (1984) 939-944
76. Mori E., Ikeda M., Hirono N., Kitagaki H., Imamura T., and Shimomura T. Amygdalar volume and emotional memory in Alzheimer's disease. The American Journal of Psychiatry 156 (1999) 216-222
77. Morris R.G. Working memory in Alzheimer-type dementia. Neuropsychology 8 (1994) 544-554
78. Naggara O., Oppenheim C., Rieu D., Raoux N., Rodrigo S., Dalla Barba G., et al. Diffusion tensor imaging in early Alzheimer's disease. Psychiatry Research 146 3 (2006) 243-249
79. Oswald W.D., and Fleischmann U.M. Nürnberger-Alters-Inventar (NAI) (1997), Hogrefe Verlag für Psychologie, Göttingen
80. Overman W.H. Sex differences in early childhood, adolescence, and adulthood on cognitive tasks that rely on orbital prefrontal cortex. Brain & Cognition 55 (2004) 134-147
81. Overman W.H., Frassrand K., Ansel S., Trawalter S., Bies B., and Redmond A. Performance on the IOWA Card task by adolescents and adults. Neuropsychologia 42 13 (2004) 1838-1851
82. Perretta J.G., Pari G., and Beninger R.J. Effects of Parkinson disease on two putative nondeclarative learning tasks: Probabilistic classification and gambling. Cognitive and Behavioural Neurology 18 (2005) 185-192
83. Perry R.J., and Hodges J.R. Attention and executive deficits in Alzheimer's disease. A critical review. Brain 122 Pt 3 (1999) 383-404
84. Rogers R.D., Owen A.M., Middleton H.C., Williams E.J., Pickard J.D., Sahakian B.J., et al. Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex. Journal of Neuroscience 19 20 (1999) 9029-9038
85. Royall D.R., Cordes J.A., and Polk M. CLOX: An executive clock drawing task. Journal of Neurology, Neurosurgery and Psychiatry 64 (1998) 588-594
86. Salmon D.P., and Bondi M.W. Neuropsychology of Alzheimer's disease. In: Terry R.D., Katzmann R., Bick K.L., and Sisodia S.S. (Eds). Alzheimer disease (1999), Lippincott Williams & Wilkins, Philadelphia 39-56
87. Seron X., Deloche G., Ferrand I., Cornet J.A., Frederix M., and Hirsbrunner T. Dot counting by brain damaged subjects. Brain and Cognition 17 (1991) 116-137
88. Stout J.C., Rodawalt W.C., and Siemers E.R. Risky decision-making in Huntington's disease. Journal of the International Neuropsychological Society 7 (2001) 92-101
89. Stout J.C., Busemeyer J.R., Lin A., Grant S.J., and Bonson K.R. Cognitive modeling analysis of decision-making processes in cocaine abusers. Psychonomic Bulletin and Review 11 (2004) 742-747
90. Tegner R., and Nyback H. To hundred and twenty four: A study of transcoding in dementia. Acta Neurologica Scandinavica 81 (1990) 177-178
91. Thiel A., Hilker R., Kessler J., Habedank B., Herholz K., and Heiss W.D. Activation of basal ganglia loops in idiopathic Parkinson's disease: A PET study. Journal of Neural Transmission 110 (2003) 1289-1301
92. Torralva T., Kipps C.M., Hodges J.R., Clark L., Bekinschtein T., Roca M., et al. The relationship between affective decision-making and theory of mind in the frontal variant of fronto-temporal dementia. Neuropsychologia 45 2 (2007) 342-349
93. Trepel C., Fox C.R., and Poldrack R.A. Prospect theory on the brain? Toward a cognitive neuroscience of decision under risk. Brain Research. Cognitive Brain Research 23 1 (2005) 34-50
94. Turnbull O.H., and Evans C.E. Preserved complex emotion-based learning in amnesia. Neuropsychologia 44 (2006) 300-306
95. Von Gunten A., Bouras C., Kovari E., Giannakopoulos P., and Hof P.R. Neural substrates of cognitive and behavioral deficits in atypical Alzheimer's disease. Brain Research Reviews 51 2 (2006) 176-211
96. Welsh K.A., Butters N., Hughes J.P., Mohs R.C., and Heymann A. Detection and staging of dementia in Alzheimer's disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer's Disease. Archives of Neurology 49 5 (1992) 448-452
97. West R.L. An application of prefrontal cortex function theory to cognitive aging. Psychological Bulletin 120 (1996) 272-292
98. West R.L. In defense of the frontal lobe hypothesis of cognitive aging. Journal of the International Neuropsychological Society 6 (2000) 727-729
99. Whitehouse P.J., Price D.L., Struble R.G., Clark A.W., Coyle J.T., and DeLong M.R. Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain. Science 215 (1982) 1237-1239
100. Whitney K.A., Fastenau P.S., Evans J.D., and Lysaker P.H. Comparative neuropsychological function in obsessive compulsive disorder and schizophrenia with and without obsessive-compulsive symptoms. Schizophrenia Research 69 (2004) 75-83
101. Winstanley C.A., Theobald D.E.H., Cardinal R.N., and Robbins T.W. Contrasting roles of basolateral amygdala orbitofrontal cortex in impulsive choice. Journal of Neuroscience 24 20 (2004) 4718-4722
102. Wood S., Busemeyer J., Koling A., Cox C.R., and Davis H. Older adults as adaptive decision makers: Evidence from the Iowa Gambling Task. Psychology of Aging 20 (2005) 220-225
103. Wynne, H. J., & Smith, G. J. (2002). Measuring gambling and problem gambling in Alberta with the Canadian Problem Gambling Index (CPGI). Final report. Edmonton (AB): Alberta Gaming Research Institute.
104. Zamarian L., Semenza C., Domahs F., Benke T., and Delazer M. Alzheimer's disease and mild cognitive impairment: Effects of shifting and interference in simple arithmetic. Journal of the Neurological Sciences 263 1-2 (2007) 79-88
105. Zamarian, L., Sinz, H., Bonatti, E., Gamboz, N., Delazer, M. (submitted for publication). Normal aging affects decisions under ambiguity, but not decisions under risk.